BIOSPECIFICS TECHNOLOGIES CORP
S-8, 1997-09-26
PHARMACEUTICAL PREPARATIONS
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   As filed with the Securities and Exchange Commission on September 26, 1997
                           Registration No. 333-______


                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549
                                 --------------

                                    FORM S-8
                             REGISTRATION STATEMENT
                                      UNDER
                           THE SECURITIES ACT OF 1933


                         BioSpecifics Technologies Corp.
               (Exact Name of issuer as specified in its charter)

            Delaware                                          11-3054851
(State or Other Jurisdiction of                            (I.R.S. Employer
 incorporation or organization)                           Identification No.)


                                35 Wilbur Street
                            Lynbrook, New York 11563
                                 (516) 593-7000
                    (Address of principal executive offices)
                                 --------------

                         BIOSPECIFICS TECHNOLOGIES CORP.
                             1997 STOCK OPTION PLAN
                            (Full title of the plan)
                                 --------------

                            ALBERT HORCHER, Secretary
                         BioSpecifics Technologies Corp.
                                35 Wilbur Street
                            Lynbrook, New York 11563
                     (Name and address of agent for service)

   Telephone number, including area code, of agent for service: (516) 593-7000
<TABLE>
<CAPTION>

                         CALCULATION OF REGISTRATION FEE
================================================================================================================================
                                                           Proposed                  Proposed
                                                            Maximum                   Maximum                 Amount of
    Title of Shares            Amount to be             Offering Price               Aggregate               Registration
   to be Registered             Registered               Per Share(1)            Offering Price(1)               Fee
- --------------------------------------------------------------------------------------------------------------------------------
<S>                           <C>                      <C>                      <C>                        <C>
Common Stock (par
value $.001 per              
share).........................500,000 shares           $4.625                   $2,312,500                 $701
================================================================================================================================

(1)       Estimated solely for the purpose of calculating the registration fee pursuant to Rule 457 of the Securities Act of 1933,
using the average of the high and low sale prices reported on the National  Association of Securities Dealers Automated  Quotation
System on September 22, 1997.

          There are also registered  hereunder such additional  indeterminate number of shares as may be issued as a result of the
antidilution provisions of the BioSpecifics Technologies Corp. 1997 Stock Option Plan.
</TABLE>

<PAGE>



                                     PART I

Item 1.   PLAN INFORMATION.

          Not included pursuant to Form S-8 instructions.

Item 2.   REGISTRANT INFORMATION AND EMPLOYEE PLAN ANNUAL INFORMATION.

          Not included pursuant to Form S-8 instructions.

                                     PART II

Item 3.   INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE.

          BioSpecifics  Technologies  Corp. (the "Company") hereby  incorporates
herein by reference the following documents:

          (1)  The  Company's  annual  report on Form  10-KSB for the year ended
               January 31, 1997;

          (2)  All  reports  filed  pursuant  to  Section  13(a) or 15(d) of the
               Securities Exchange Act of 1934, as amended (the "Exchange Act"),
               on or after January 31, 1997, including the Company's Form 10-QSB
               for the period ended July 31, 1997; and

          (3)  The  description of the Company's  Common Stock  contained in the
               Company's  Registration  Statement  on Form  8-A  filed  with the
               Securities and Exchange Commission (the "Commission") on February
               21, 1992,  including any amendments thereto and any reports filed
               for the purpose of updating such description  (the  "Registration
               Statement").

          In addition,  all documents filed by the Company  pursuant to Sections
13(a),  13(c),  14 and 15(d) of the Exchange Act  subsequent to the date of this
registration  statement  and prior to the filing of a  post-effective  amendment
which  indicates  that all  securities  offered  herein  have been sold or which
deregisters  all  securities  then  remaining  unsold  shall  be  deemed  to  be
incorporated  herein by  reference  and to be a part hereof from the  respective
date of filing of each such document.

Item 4.   DESCRIPTION OF SECURITIES.

          Not applicable.

Item 5.   INTERESTS OF NAMED EXPERTS AND COUNSEL.

          Not applicable.

Item 6.   INDEMNIFICATION OF DIRECTORS AND OFFICERS.

          Section 145 of the Delaware General Corporation Law provides generally
that a person sued as a director,  officer,  employee or agent of a  corporation


                                        2

<PAGE>


may be  indemnified  by the  corporation  in  nonderivative  suits for  expenses
(including attorneys' fees), judgments,  fines and amounts paid in settlement if
such person acted in good faith and in a manner he or she reasonably believed to
be in the best interest of the corporation.  In the case of criminal actions and
proceedings,  such person must also have had no reasonable  cause to believe his
or her conduct was  unlawful.  Indemnification  of  expenses  is  authorized  in
stockholder  derivative suits where such person in good faith and in a manner he
or she reasonably believed to be in the best interests of the corporation and so
long as he had not  been  found  liable  for  negligence  or  misconduct  in the
performance of his duty to the corporation.  Even in this latter  instance,  the
court  may  determine  that  in view of all the  circumstances  such  person  is
entitled to indemnification for such expenses as the court deems proper.

          The  Company's   By-laws  authorize   indemnification   of  directors,
officers,  employees and agents on the terms and conditions set forth in Section
145 of the Delaware General Corporation Law.

          Insofar  as   indemnification   for  liabilities   arising  under  the
Securities  Act of 1933, as amended (the "Act"),  may be permitted to directors,
officers  and  controlling  persons of the  Company  pursuant  to the  foregoing
provisions,  or  otherwise,  the Company has been advised that in the opinion of
the Commission such indemnification is against public policy as expressed in the
Act  and  is,  therefore,   unenforceable.   In  the  event  that  a  claim  for
indemnification  against such liabilities (other than the payment by the Company
of expenses incurred or paid by a director, officer or controlling person of the
Company in the successful defense of any action, suit or proceeding) is asserted
by  such  director,  officer  or  controlling  person  in  connection  with  the
securities  being  registered,  the Company  will,  unless in the opinion of its
counsel the matter has been settled by controlling precedent,  submit to a court
of appropriate  jurisdiction the question whether such  indemnification by it is
against  public policy as expressed in the Act and will be governed by the final
adjudication of such issue.

Item 7.   EXEMPTION FROM REGISTRATION CLAIMED.

          Not applicable.

Item 8.  EXHIBITS.

Exhibit No.                             Exhibit
- -----------                             -------

     3.1                 Certificate    of   Amendment   of    Certificate    of
                         Incorporation of the Company (incorporated by reference
                         from the Company's Registration Statement on Form S-18,
                         filed  with  the   Commission   on  November  14,  1991
                         (Registration No.  33-40850-NY (the "1991  Registration
                         Statement")).

     3.2                 By-Laws of the  Company,  as amended  (incorporated  by
                         reference from the 1991 Registration Statement).

     4.1                 BioSpecifics Technologies Corp. 1997 Stock Option Plan.

     23.1                Consent   of  KPMG  Peat   Marwick   LLP,   independent
                         accountants.

     24.1                Power of Attorney  (included on signature  page of this
                         Form S-8).


                                        3

<PAGE>



Item 9.   UNDERTAKINGS.

          (a)  The undersigned hereby undertakes:

          (1)  to file, during  any  period  in which  offers or sales are being
made, a post-effective amendment to this registration statement:

               (i)  To include any  prospectus  required by Section  10(a)(3) of
               the Act;

               (ii) To reflect  in the  prospectus  any facts or events  arising
               after the effective date of this  registration  statement (or the
               most recent post-effective amendment thereof) which, individually
               or in  the  aggregate,  represent  a  fundamental  change  in the
               information set forth in this registration statement; and

               (iii)To include  any  material  information  with  respect to the
               plan  of   distribution   not   previously   disclosed   in  this
               registration statement or any material change to such information
               in this registration statement;

provided,  however, that paragraphs (a)(1)(i) and (a)(1)(ii) do not apply if the
- --------   -------
information to be included in a post-effective  amendment by those paragraphs is
contained  in periodic  reports  filed by the Company  pursuant to Section 13 or
Section  15(d) of the  Exchange Act that are  incorporated  by reference in this
registration statement.

          (2) that, for the purpose of determining  any liability under the Act,
each such  post-effective  amendment  shall be  deemed to be a new  registration
statement relating to the securities  offered therein,  and the offering of such
securities  at that time shall be deemed to be the  initial  bona fide  offering
thereof; and

          (3) to remove from registration by means of a post-effective amendment
any of the securities being registered which remain unsold at the termination of
the offering.

          (b)  The undersigned  Company hereby  undertakes that, for purposes of
               determining  any  liability  under  the Act,  each  filing of the
               Company's  Annual  Report  pursuant  to Section  13(a) or Section
               15(d) of the Exchange Act (and, where applicable,  each filing of
               an employee  benefit  plan's  Annual  Report  pursuant to Section
               15(d) of the Exchange Act) that is  incorporated  by reference in
               this  registration   statement  shall  be  deemed  to  be  a  new
               registration   statement   relating  to  the  securities  offered
               therein,  and the offering of such  securities at that time shall
               be deemed to be the initial bona fide offering thereof.

          (c)  Insofar as indemnification  for liabilities arising under the Act
               may be permitted to directors,  officers and controlling  persons
               of  the  Company  pursuant  to  the  foregoing   provisions,   or
               otherwise,  the Company has been  advised  that in the opinion of
               the Commission such  indemnification  is against public policy as
               expressed  in the Act and is,  therefore,  unenforceable.  In the
               event that a claim for  indemnification  against such liabilities
               (other than the  payment by the  Company of expenses  incurred or
               paid by a director,  officer or controlling person of the Company
               in the successful  defense of any action,  suit or proceeding) is


                                        4

<PAGE>


               asserted  by such  director,  officer  or  controlling  person in
               connection  with the  securities  being  registered,  the Company
               will,  unless in the  opinion of its  counsel the matter has been
               settled  by   controlling   precedent,   submit  to  a  court  of
               appropriate    jurisdiction    the    question    whether    such
               indemnification  by it is against  public  policy as expressed in
               the Act and will be  governed by the final  adjudication  of such
               issue.


                                        5

<PAGE>




                                   SIGNATURES

          Pursuant  to the  requirements  of the  Securities  Act of  1933,  the
Registrant  has duly  caused  this  Registration  Statement  to be signed on its
behalf by the undersigned,  thereunto duly authorized,  in the City of Lynbrook,
State of New York on this day of September 26, 1997.

                                        BIOSPECIFICS TECHNOLOGIES CORP.


                                        /S/ EDWIN H. WEGMAN
                                        ---------------------------------------
                                        By: Edwin H. Wegman
                                            Chairman and President



                                POWER OF ATTORNEY

          Each  of  the  undersigned  officers  and  directors  of  BioSpecifics
Technologies Corp. hereby severally  constitutes and appoints Albert Horcher and
Thomas  L.  Wegman,  and each of them  severally,  as  attorney-in-fact  for the
undersigned, in any and all capacities, with full power of substitution, to sign
this Registration  Statement and any amendments to this  Registration  Statement
(including  post-effective  amendments),  and to file  the  same  with  exhibits
thereto and other  documents in connection  therewith,  with the  Securities and
Exchange  Commission,   granting  unto  said  attorney-in-fact  full  power  and
authority to do and perform  each and every act  requisite  and  necessary to be
done in and about the  premises,  as fully to all intents and  purposes as he or
she might or could do in person,  hereby  ratifying and confirming all that said
attorney-in-fact may lawfully do or cause to be done by virtue hereof.

          Pursuant  to the  requirements  of the  Securities  Act of 1933,  this
Registration  Statement  has been signed below by the  following  persons in the
capacities and on the dates indicated.

<TABLE>
<CAPTION>
<S>                                         <C>                                                       <C>

/S/ EDWIN H. WEGMAN                          Chairman of the Board, President and                      September 26, 1997
- -----------------------                      Director (Principal Executive Officer)  
  Edwin H. Wegman                         

/S/ ALBERT HORCHER                           Secretary and Treasurer, Principal                        September 26, 1997
- -----------------------                      Financial and Chief Accounting Officer
  Albert Horcher                

/S/ THOMAS L. WEGMAN                         Executive Vice President and Director                     September 26, 1997
- -----------------------
  Thomas L. Wegman

/S/ PAUL A. GITMAN                           Director                                                  September 26, 1997
- -----------------------
  Paul A. Gitman, M.D.

/S/ HENRY MORGAN                             Director                                                  September 26, 1997
- -----------------------
  Henry Morgan

                                             Director                                                  September 26, 1997
- -----------------------
  Sherman C. Vogel

/S/ RAINER FRIEDEL                           Director                                                  September 26, 1997
- -----------------------
  Rainer Friedel

</TABLE>

<PAGE>



                                INDEX TO EXHIBITS

          The  following  is a complete  list of exhibits  filed as part of this
registration statement:

Exhibit No.                                       Exhibit
- -----------                                       -------

     3.1                 Certificate    of   Amendment   of    Certificate    of
                         Incorporation of the Company (incorporated by reference
                         from the Company's Registration Statement on Form S-18,
                         filed  with  the   Commission   on  November  14,  1991
                         (Registration No.  33-40850-NY (the "1991  Registration
                         Statement")).

     3.2                 By-Laws of the  Company,  as amended  (incorporated  by
                         reference from the 1991 Registration Statement).

     4.1                 BioSpecifics Technologies Corp. 1997 Stock Option Plan.

     23.1                Consent   of  KPMG  Peat   Marwick   LLP,   independent
                         accountants.

     24.1                Power of Attorney  (included on signature  page of this
                         Form S-8).





                         BIOSPECIFICS TECHNOLOGIES CORP.

                             1997 STOCK OPTION PLAN

          1.   Name and Purpose.  The purpose of this Plan, which shall be known
as the "BioSpecifics Technologies Corp. 1997 Stock Option Plan" (the "Plan"), is
to advance the interests of BioSpecifics  Technologies  Corp. (the "Company") by
providing  a  material  incentive  for  the  continued  services  of  those  key
employees,  independent  agents,  consultants,  attorneys  and  directors of the
Company  or its  Subsidiaries  who made  significant  contributions  toward  the
Company's   success  and  development,   by  encouraging  those  key  employees,
independent  agents,  consultants,  attorneys  and  directors to increase  their
proprietary  interest in the Company and by attracting  new, able  executives to
employment with the Company or its Subsidiaries.

          2.   Definitions. For purposes of this Plan, the following terms, when
capitalized,  shall  have the  meanings  designated  herein  unless a  different
meaning is plainly required by the context.

               (a) "Board" shall mean the Board of Directors of the Company.

               (b)  "Code"  shall mean the  Internal  Revenue  Code of 1986,  as
amended.

               (c) "Committee"  shall mean a Stock Option  Committee of not less
than two  directors of the Company,  each of whom is a  "non-employee"  director
within the meaning of Rule  16b-3(c)  under the  Exchange Act and/or an "outside
director"  within the  meaning of  Section  162(m)(4)(c)(I)  of the Code and the
Treasury Regulations issued thereunder.

               (d) "Common Shares" shall mean the shares of the Company's common
stock, par value $.001 per share.

               (e) "Consultant" shall mean any independent agent,  consultant or
attorney to or for the Company or a Subsidiary who, in the opinion of the Board,
has  demonstrated a capacity for  contributing  in a substantial  measure to the
success of the Company and its Subsidiaries.

               (f) "Effective Date" shall mean the date on which this Plan shall
have been approved by the directors and shareholders of the Company.

               (g)  "Exchange  Act" shall mean the  Securities  Exchange  Act of
1934,  as amended.  

               (h) "Fair  Market  Value" of the Common  Shares on a certain date
shall  mean,  if the Common  Shares are listed on the  National  Association  of



<PAGE>


Securities  Dealers Automated  Quotation System  ("NASDAQ"),  the average of the
closing bid and ask prices as quoted on NASDAQ on the date specified,  or if the
Common Shares are not quoted on NASDAQ on such date, on the next  preceding date
on which the Common  Shares are traded.  If the Common  Shares are not listed on
NASDAQ, then "Fair Market Value" of the Common Shares on a certain date shall be
that value which the Board or the Committee determines, in good faith, to be the
fair market value of the Common Shares on such date.

               (i) "Key  Employee"  shall mean any  employee of the Company or a
Subsidiary  who, in the opinion of the Board,  has  demonstrated  a capacity for
contributing  in a  substantial  measure to the  success of the  Company and its
Subsidiaries.

               (j)  "Non-Qualified  Stock  Options"  shall  mean  those  options
granted by the Company  pursuant to this Plan which do not qualify for favorable
tax treatment under Section 422 of the Code.

               (k)  "Participant"  shall  mean  a  Key  Employee,  Participating
Director  or  Consultant  selected  by the  Board to  receive  options,  whether
Qualified Incentive Stock Options or Non-Qualified Stock Options,  granted under
this Plan.

               (l)  "Participating  Director"  shall  mean any  director  of the
Company or any Subsidiary who, in the opinion of the Board,  has  demonstrated a
capacity for contributing in a substantial measure to the success of the Company
and its Subsidiaries.

               (m) "Qualified  Incentive Stock Options" shall mean those options
granted by the Company  pursuant to this Plan which  qualify for  favorable  tax
treatment under Section 422 of the Code.

               (n)  "Retirement"  shall mean  retirement  (i) on or after age 55
with 20 or more  years of  service,  (ii) on or after  age 60 or (iii)  with the
consent of the Committee.

               (o)  "Securities  Act" shall mean the  Securities Act of 1933, as
amended.

               (p)  "Subsidiary"  shall  mean a  subsidiary  corporation  of the
Company as defined in Section 424(f) of the Code.

          3.   Administration; Selection of Participants.

               (a) This Plan shall be  administered  by the  Committee  or, with
respect  to  non-employee   directors,   the  Board,   which  shall  select  the
Participants  and shall grant to the  Participants  stock options under,  and in
accordance  with, the provisions of this Plan. If the Committee is administering


                                       2

<PAGE>


the Plan, it shall report all action taken by it to the Board which shall review
and ratify or approve  those actions which are required by law to be so reviewed
and ratified or approved by the Board.  To the extent the Committee  administers
this Plan, all references  herein to the "Board" shall mean the "Committee." The
stock options  granted under this Plan may be either  Qualified  Incentive Stock
Options or  Non-Qualified  Stock  Options,  within the  discretion of the Board.
Non-Qualified  Stock  Options may be granted to any  Participant,  including Key
Employees,  Consultants and Participating  Directors.  Qualified Incentive Stock
Options may be awarded only to Key  Employees  (including  directors who are Key
Employees).

               (b) Subject to the  express  provisions  of this Plan,  the Board
shall  have  authority  to  (i)  adopt  regulations  and  procedures  which  are
consistent  with the terms of this  Plan;  (ii)  adopt and  amend  stock  option
agreements  between the Company and a Participant  as they deem advisable and to
determine the terms and  provisions of such stock option  agreements,  including
the number of shares with respect to which options are granted to a Participant,
the option price for such shares, and the date or dates when the option or parts
of it may be exercised,  the restrictions  applicable thereto, which need not be
identical,  and which terms shall  comply with any  applicable  requirements  of
Paragraph 5 below; (iii) construe and interpret such stock option agreements and
to impose therein such  limitations and  restrictions as are deemed necessary or
advisable  by  counsel  for the  Company  so that  compliance  with the  federal
securities  laws and with  the  securities  laws of the  various  states  may be
assured;  and (iv) make all other  determinations  necessary  or  advisable  for
administering  this Plan.  All decisions and  interpretations  made by the Board
shall be binding and conclusive on all Participants, their legal representatives
and beneficiaries.

          4.   Shares Subject to the Plan.

               (a) The Shares to be issued and  delivered  by the  Company  upon
exercise of options granted under this Plan (whether  Qualified  Incentive Stock
Options or  Non-Qualified  Stock  Options) are the Common  Shares,  which may be
either  authorized but unissued shares, or treasury shares, in the discretion of
the Board.

               (b) The aggregate number of the Common Shares which may be issued
under this Plan shall be 500,000;  subject, however, to the adjustments provided
in Paragraphs 10 and 18 after the  Effective  Date.  The Board may, from time to
time, increase the number of Shares available for grant under this Plan.

               (c) Shares  covered by an option  which is no longer  exercisable
with respect to such shares shall again be available  for issuance in connection
with other options granted under this Plan.

                                       3
<PAGE>


               (d) During  any  calendar  year,  no  Participant  may be granted
options  pursuant to this Plan on more than 350,000 Common Shares subject to the
adjustments provided in Paragraphs 10 and 18 after the Effective Date.


          5.   Terms of  Options.  Options  granted  under  this  Plan  shall be
evidenced by stock option  agreements  authorized by the Board and executed by a
duly  authorized  officer of the  Company.  Such stock option  agreements  shall
contain  such  terms as the Board  shall  determine,  subject  to the  following
limitations and requirements:

               (a) Option Price:  The option price per Common Share shall be not
less  than 100% of the Fair  Market  Value of the  Common  Shares on the date of
grant of such option; provided,  however, that the option price of any Qualified
Incentive  Stock Options  granted to any  stockholder of the Company who owns at
least 10% of the Common  Shares  shall not be less than 110% of such Fair Market
Value.

               (b) Period  within  which  option may be  exercised:  In general,
options  granted under this Plan will become  exercisable in four equal,  annual
installments commencing one year after the date the option is granted,  although
the Board, in its discretion,  may provide for different vesting schedules. Each
option granted under this Plan shall terminate  (become  non-exercisable)  after
the  expiration  of ten years from the date of grant of such  option;  provided,
however,  that Qualified  Incentive  Stock Options granted to any stockholder of
the Company who owns, at the time of grant,  at least 10% of the Common  Shares,
shall  terminate  after the  expiration  of five years from the date of grant of
such option.

               (c) Termination of option by reason of termination of employment,
consultancy or  directorship:  Upon  termination of a Key Employee's  employment
with the Company or a  Subsidiary,  all options  granted under this Plan to such
Participant  which are not  exercisable  on the date of such  termination  shall
immediately terminate,  and any remaining exercisable options shall terminate if
not exercised before the expiration of the applicable period specified below, or
at such earlier time as may be applicable under subparagraph 5(b) above:

                    (i)  No  later  than   thirty  (30)  days   following   such
               termination of employment if such termination was not a result of
               death or retirement of the Participant.

                    (ii) No later than six (6) months following such termination
               of  employment  if such  termination  was  because  of death,  or
               because of retirement under the provisions of any retirement plan
               of the  Company  or any  Subsidiary,  or with the  consent of the
               Company.

          Whether  time spent on leave of absence  granted by the Company or any
Subsidiary shall contribute continued employment for purposes of this Plan shall
be determined by the Board in its sole discretion.

                                       4
<PAGE>

          Notwithstanding the foregoing,  the Board may, in its sole discretion,
impose more  restrictive  conditions on the exercise of an option  granted under
this Plan,  including,  without limitation,  restrictions  relating to length of
service,  corporate  performance,  attainment of individual or group performance
objectives, resale restrictions,  federal or state securities laws and providing
for no exercise of any option after termination of a Key Employee's  employment.
Any and all such  conditions  shall be specified  in the stock option  agreement
limiting and defining such option.

          The Board may, in its sole discretion,  impose similar conditions upon
the exercise of any options granted to Consultants or to Participating Directors
(who are not Key Employees), but is not required to do so.

               (d)  Non-transferability:  No option  under  this  Plan  shall be
assignable or transferable  except,  in the event of the death of a Participant,
by his or her will or by the laws of descent and  distribution.  In the event of
the death of a Participant,  the representative or representatives of his or her
estate,  or the person or persons who acquired (by bequest or  inheritance)  the
rights to  exercise  his or her stock  options  granted  under  this  Plan,  may
exercise any of the unexercised  options or part thereof prior to the expiration
of the applicable  exercise period, as specified in sub-paragraphs 5(b) and 5(c)
above, or in the stock option agreement relating to such options. No transfer of
an option by a participant by will or by laws of descent and distribution  shall
be effective to bind the Company  unless the Company  shall have been  furnished
with written  notice  thereof and a copy of the will and such other  evidence as
the Company may deem necessary to establish the validity of the transfer and the
acceptance by the  transferee or transferees of the terms and conditions of such
option.

               (e) More than one option granted to a Participant:  More than one
option,  and more than one form of option, may be granted to a Participant under
this Plan.

               (f)  Partial  exercise:  Unless  otherwise  provided in the stock
option agreement,  any exercise of an option granted under this Plan may be made
in whole or in part.

               (g)  Limitation on Amount of Qualified  Incentive  Stock Options:
The aggregate  fair market value  (determined at the time the option is granted)
with respect to which Qualified  Incentive Stock Options become exercisable by a
Participant  for the first time during any  calendar  year  (including  all such
plans of the Company and its Subsidiaries) shall not exceed $100,000.

          6. Period of Granting  Options.  No option shall be granted under this
Plan subsequent to ten years after the Effective Date.

                                       5
<PAGE>

          7. No  Effect  Upon  Employment  Status.  The fact  that an  employee,
independent  agent,  consultant,  attorney  or director  has been  selected as a
Participant  shall  not  limit  or  otherwise  qualify  the  right of his or her
employer to terminate his or her  employment,  engagement or directorship at any
time.

          8.  Method of  Exercise.  Any  option  granted  under this Plan may be
exercised  by written  notice to the  Secretary  of the  Company,  signed by the
Participant, or by such other person as is entitled to exercise such option. The
notice of  exercise  shall  state the  number of shares in  respect of which the
option is being  exercised,  and shall be accompanied  by the payment,  in cash,
and/or,  as provided below,  in the Common Shares,  of the full option price for
such shares.  At the written request of the Participant and upon approval by the
Board, shares acquired pursuant to the exercise of any option may be paid for at
the time of  exercise  by the  surrender  of  Common  Shares  held by or for the
account of the  Participant  at the time of exercise  (for  Qualified  Incentive
Stock Options only to the extent  permitted by subsection (c) (4) of Section 422
of the Code,  without  liability to the Company).  In such case, the fair market
value of the surrendered  shares shall be determined by the Board as of the date
of exercise in the same manner as such value is determined  upon the grant of an
option. A certificate or certificates  for the Common Shares  purchased  through
the  exercise  of an  option  shall be issued in the  regular  course  after the
exercise  of the option and  payment  therefor.  The  Company  shall be afforded
reasonable  opportunity  after  exercise  of  any  option  to  comply  with  any
requirements  for stock exchange  listing,  for  registration  under  applicable
securities or other laws and for compliance with other laws and regulations,  if
any, before issuance of the shares being purchased on such exercise.  During the
option period, no person entitled to exercise any option granted under this Plan
shall have any of the rights or privileges of a shareholder  with respect to any
shares  issuable  upon exercise of such option until  certificates  representing
such shares shall have been issued and delivered.

          9. Implied Consent of Participants.  Every Participant,  by his or her
acceptance of an option under this Plan, shall be deemed to have consented to be
bound, on his or her own behalf and on behalf of his or her heirs,  assigns, and
legal representatives, by all of the terms and conditions of this Plan.

          10. Share Adjustments.  In the event there is any change in the Common
Shares resulting from stock splits, stock dividends of more than 5% in any year,
combinations  or  exchanges of shares,  or other  similar  capital  adjustments,
equitable proportionate adjustments shall be made by the Board in (1) the number
of shares available for option under this Plan, (2) the number of shares subject
to options granted under this Plan, and (3) the option price of optioned shares.

          11. Merger, Consolidation, or Sale of Assets. In the event the Company
shall  consolidate with, merge into, or transfer all or substantially all of its
assets to another corporation or corporations  (herein referred to as "successor
employer corporation"),  such successor employer corporation may obligate itself
to  continue  this  Plan and to  assume  all  obligations  under  this Plan (for
Qualified Incentive Stock Options, in a manner consistent with the provisions of
Section  424(a) of the Code,  or the  provisions  of that  Section  as it may be
hereafter  amended or as it may be replaced by any other  section or sections of
the Code of like intent or purpose).  In the event that such successor  employer
corporation  does not obligate  itself to continue this Plan as above  provided,

                                       6


<PAGE>


this Plan shall terminate upon such consolidation,  merger or transfer,  and any
option previously granted hereunder shall terminate.  If practical,  the Company
shall give each  Participant  twenty  (20) days'  prior  notice of any  possible
transaction which might terminate this Plan and the options  previously  granted
hereunder.

          12.  Conflicting  Provisions.  In case  of any  conflict  between  the
provisions of this Plan and the provisions of a stock option  agreement  entered
into pursuant to this Plan, the provisions of this Plan shall control.

          13. Company  Responsibility.  All expenses of this Plan, including the
cost of maintaining  records,  shall be borne by the Company.  The Company shall
have no  responsibility  or  liability  for any act or thing done or left undone
with respect to the price, time,  quality, or other conditions and circumstances
of the purchase of shares  under the terms of this Plan,  so long as the Company
acts in good faith.

          14. Use of  Proceeds.  The  proceeds  received by the Company from the
sale of stock under this Plan shall be added to the general funds of the Company
and shall be used for such corporate purposes as the Board shall direct.

          15. Tax Treatment.  With respect to Qualified Incentive Stock Options,
this Plan is intended to comply with the  provisions of Section 422 of the Code.
Any  provisions of this Plan which  conflict with the  provisions of Section 422
shall be deemed to be hereby amended so as to comply therewith.

          16. Law Governing.  This Plan and the rights of all persons  hereunder
shall be governed by, and construed and enforced in accordance with, the laws of
the State of Delaware.

          17. Securities Laws. The Board shall take all necessary or appropriate
actions to ensure that all option  grants and all  exercises  thereof under this
Plan are in full compliance with all federal and state securities laws.

          18.  Withholding  and  Deductions.  Notwithstanding  anything  to  the
contrary contained herein, if at any time specified herein for the making of any
payment of cash or any delivery of Option stock to any person,  by reason of the
grant of an option, the exercise thereof, or otherwise, any law or regulation of
any governmental authority having jurisdiction in the premises shall require the
Company to withhold,  or to make any  deduction  for any taxes or take any other
action in connection  with the payment or delivery then to be made, such payment
or delivery,  as the case may be, shall be deferred  until such  withholding  or
deduction shall have been adequately  provided for, in the opinion of the Board.
18. 


                                       7
 
<PAGE>

          19. Amendment and Termination. The Board may alter, amend or terminate
this Plan at any time, or from time to time,  without  obtaining any approval of
the  Company's  shareholders;  except  that this Plan may not be  amended to (a)
change the option price of optioned shares (excepting proportionate  adjustments
made under Paragraph 10); (b) change the  requirement  that the option price per
Common Share not be less than 100% of the Fair Market Value of the Common Shares
on the  date  the  option  is  granted  (or  less  than  110% in the case of 10%
stockholders being issued Qualified Incentive Stock Options);  (c) to extend the
time within  which  options  may be granted or the time  within  which a granted
option  may  be  exercised;  or  (d)  to  change,  without  the  consent  of the
Participant, any option previously granted to him or her under this Plan, except
as provided  herein.  If this Plan is terminated,  any unexercised  option shall
continue to be exercisable in accordance  with its terms,  except as provided in
paragraph 11 above.

          20.  Variations in Pronouns.  Whenever  used in this Plan,  unless the
context  otherwise  requires,  words used in the singular shall also include the
plural,  and words used in the masculine  gender shall also include the feminine
or neuter gender.

          21. Captions and Headings. The Paragraph and subparagraph headings and
captions  are for  reference  purposes  only and shall not in any way affect the
meaning or interpretation of any such Paragraph or subparagraph of this Plan.












                                       8



KPMG PEAT MARWICK LLP



                         Independent Auditors' Consent
                         -----------------------------


Board of Directors
Biospecifics Technologies Corp.:


We consent to the use of our report dated April 18, 1997 incorporated  herein by
reference.


                                             /S/ KPMG PEAT MARWICK LLP
                                             ----------------------------------
                                             KPMG PEAT MARWICK LLP

Jericho, New York
September 22, 1997



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