METRA BIOSYSTEMS INC
8-A12G/A, 1997-01-27
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                                                        Total Number of Pages __
                                                    Index to Exhibits at Page 10


                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549
                                   -----------

                                   FORM 8-A/A

                FOR REGISTRATION OF CERTAIN CLASSES OF SECURITIES
                    PURSUANT TO SECTION 12 (b) OR (g) OF THE
                         SECURITIES EXCHANGE ACT OF 1934

                             METRA BIOSYSTEMS, INC.
                             ----------------------
             (Exact name of registrant as specified in its charter)

          California                                         33-0408436  
- -----------------------------------                        --------------
(State of incorporation or organization)                   (IRS Employer 
                                                           Identification No.)


265 North Whisman Road, Mountain View, CA                    94043     
- -----------------------------------------                ------------
(Address of principal executive offices)                  (Zip Code)

Securities to be registered pursuant to Section 12(b) of the Act:

     Title of each class                          Name of each exchange on which
     to be so registered                          each class is to be registered
     -------------------                          ------------------------------

        None                                           None

        Securities to be registered pursuant to Section 12(g) of the Act:


                         Preferred Share Purchase Rights
                         -------------------------------
                                (Title of Class)

<PAGE>

Item 1.   DESCRIPTION OF SECURITIES TO BE REGISTERED.

     On August 21, 1996, the Board of Directors of Metra Biosystems, Inc. 
(the "Company") declared a dividend of one preferred share purchase right (a 
"Right") for each outstanding share of Common Stock, $0.001 par value (the 
"Common Shares"), of the Company. The dividend is payable on September 5, 
1996 (the "Record Date") to shareholders of record as of the close of 
business on that date. Each Right entitles the registered holder to purchase 
from the Company one one-thousandth of a share of Series A Participating 
Preferred Stock, $0.001 par value, of the Company (the "Preferred Shares"), 
subject to adjustment, at a price of $50.00 per share, subject to adjustment 
(the "Purchase Price"). The description and terms of the Rights are set 
forth in a Preferred Shares Rights Agreement (as amended, the "Rights 
Agreement") dated as of August 21, 1996 and as amended January 17, 1997 
between the Company and The First National Bank of Boston as Rights Agent 
(the "Rights Agent").

     The following is a general description only and is subject to the 
detailed terms and conditions of the Rights Agreement. A copy of the Rights 
Agreement, including the Certificate of Determination, the form of Rights 
Certificate and the Summary of Rights to be provided to shareholders of the 
Company, is attached as Exhibit 1 to this Registration Statement and is 
incorporated herein by reference. A copy of Amendment No. 1 to the Rights 
Agreement is attached as Exhibit 2 to this Registration Statement and is 
incorporated herein by reference.

RIGHTS EVIDENCED BY COMMON SHARE CERTIFICATES

     The Rights will not be exercisable until the Distribution Date (defined 
below). Accordingly, Common Share certificates outstanding on the Record 
Date will evidence the Rights related thereto, and Common Share certificates 
issued after the Record Date will contain a notation incorporating the Rights 
Agreement by reference. Until the Distribution Date (or earlier redemption, 
exchange or expiration of the Rights), the surrender or transfer of any 
certificates for Common Shares, even without notation or a copy of the 
Summary of Rights being attached thereto, will also constitute the transfer 
of the Rights associated with the Common Shares represented by such 
certificate.

                                       -2-

<PAGE>

DISTRIBUTION DATE

     The Rights will separate from the Common Shares, certificates for the 
Rights ("Rights Certificates") will be issued and the Rights will become 
exercisable upon the earlier of:  (i) the close of business on the tenth day 
(or such later date as may be determined by a majority of the Board of 
Directors, excluding directors affiliated with the Acquiring Person, as 
defined below (the "Continuing Directors")) following a public announcement 
that a person or group of affiliated or associated persons has acquired, or 
obtained the right to acquire, beneficial ownership of 20% or more of the 
outstanding Common Shares (an "Acquiring Person") or (ii) the close of 
business on the tenth day (or such later date as may be determined by a 
majority of the Continuing Directors) following the commencement of a tender 
offer or exchange offer, the consummation of which would result in the 
beneficial ownership by a person or group of 30% or more of the outstanding 
Common Shares. The earlier of such dates is referred to as the "Distribution 
Date".

ISSUANCE OF RIGHTS CERTIFICATES, EXPIRATION OF RIGHTS

     As soon as practicable following the Distribution Date, separate Rights 
Certificates will be mailed to holders of record of the Common Shares as of 
the close of business on the Distribution Date and such separate Rights 
Certificates alone will evidence the Rights from and after the Distribution 
Date. Unless otherwise determined by the Board of Directors, all Common 
Shares issued prior to the Distribution Date will be issued with Rights.
Common Shares issued after the Distribution Date may be issued with Rights if 
such shares are issued (i) upon the exercise, conversion or exchange of 
securities issued after adoption of the Rights Agreement or (ii) pursuant to 
the exercise of stock options or under any employee benefit plan or 
arrangement. Except as otherwise determined by the Board of Directors, no 
other Common Shares issued after the Distribution Date will be issued with 
Rights. In addition, no Common Shares issued after the Distribution Date 
will be issued with Rights if such issuance would result in (or create a 
significant risk) (i) of material adverse tax consequences to the Company or 
the person to whom such Rights Certificate would be issued or (ii) that such 
options or plans would not qualify for otherwise available special tax 
treatment. The Rights will expire on August 21, 2006 (the "Final 

                                       -3-

<PAGE>

Expiration Date"), unless the Final Expiration Date is extended or unless the 
Rights are earlier redeemed or exchanged by the Company or expire upon 
consummation of certain mergers, consolidations or sales of assets, as 
described below.

INITIAL EXERCISE OF THE RIGHTS

     Following the Distribution Date, and until the occurrence of one of the 
subsequent events described below, holders of the Rights will be entitled to 
receive, upon exercise and the payment of $50.00 (the "Purchase Price") per 
Right, one one-thousandth of a Preferred Share.

EXCHANGE PROVISION

     At any time after an Acquiring Person has become such and prior to the 
Acquiring Person beneficially owning 50% or more of the outstanding Common 
Shares, the Board of Directors of the Company may exchange the Rights (other 
than Rights owned by the Acquiring Person or its affiliates), in whole or in 
part, at an exchange ratio of one Common Share per Right (subject to 
adjustment). 

RIGHT TO BUY COMMON SHARES AT HALF PRICE

     Unless the Rights are earlier redeemed or exchanged, in the event that 
an Acquiring Person becomes such, other than pursuant to a tender offer which 
is made for all of the outstanding Common Shares and approved by a majority 
of the Continuing Directors after determining that the offer is both adequate 
and otherwise in the best interests of the Company and its shareholders (a 
"Permitted Offer"), then proper provision will be made so that each holder of 
a Right which has not theretofore been exercised (other than Rights 
beneficially owned by the Acquiring Person, which will thereafter be void) 
will thereafter have the right to receive, upon exercise of a Right, a number 
of Common Shares having a then current value equal to two times the Purchase 
Price. In the event that the Company does not have a sufficient number of 
Common Shares available, or the Board decides that such action is necessary 
or appropriate and not contrary to the interests of Rights holders, the 
Company may, among other things, instead substitute cash, assets or other 
securities for the Common Shares into which the Rights would have otherwise 
been exercisable. 

                                       -4-

<PAGE>

RIGHT TO BUY ACQUIRING COMPANY STOCK AT HALF PRICE

     Similarly, unless the Rights are earlier redeemed or exchanged, in the 
event that, after the Shares Acquisition Date (as defined below), (i) the 
Company consolidates with or merges into another entity, (ii) another entity 
consolidates with or merges into the Company or (iii) the Company sells or 
otherwise transfers 50% or more of its consolidated assets or earning power, 
proper provision must be made so that each holder of a Right which has not 
theretofore been exercised (other than Rights beneficially owned by the 
Acquiring Person, which will thereafter be void) will thereafter have the 
right to receive, upon exercise, a number of shares of common stock of the 
acquiring company having a then current value equal to two times the Purchase 
Price (unless the transaction satisfies certain conditions and is consummated 
with a person who acquired shares pursuant to a Permitted Offer, in which 
case the Rights will expire).

ADJUSTMENTS TO PREVENT DILUTION

     The Purchase Price payable, the number of Rights and the number of 
Preferred Shares, Common Shares or other securities or property issuable upon 
exercise of the Rights are subject to adjustment from time to time to prevent 
dilution as set forth in the Rights Agreement. With certain exceptions, no 
adjustment in the Purchase Price will be required until cumulative 
adjustments require an adjustment of at least 1% in such Purchase Price. 

RIGHTS AND PREFERENCES OF THE PREFERRED SHARES

     Preferred Shares purchasable upon exercise of the Rights will not be 
redeemable. Each Preferred Share will be entitled to an aggregate dividend 
of 1,000 times the dividend declared per Common Share. In the event of 
liquidation, the holders of the Preferred Shares will be entitled to a 
preferential liquidation payment equal to accrued but unpaid dividends plus 
the greater of $1,000 per share and 1,000 times the aggregate per share 
amount to be distributed to the holders of Common Shares. Each Preferred 
Share will have 1,000 votes, voting together with the holders of Common 
Shares, except as required by law or the Certificate of Determination of 
Rights, Preferences and Privileges of Series A Participating Preferred Stock.
In the event of any merger, 

                                       -5-

<PAGE>

consolidation or other transaction in which Common Shares are changed or 
exchanged, each Preferred Share will be entitled to receive 1,000 times the 
amount received per Common Share. These rights are protected by customary 
anti-dilution provisions. Because of the nature of the dividend, liquidation 
and voting rights of the Preferred Shares, the value of the one 
one-thousandth interest in a Preferred Share purchasable upon exercise of 
each Right should approximate the value of one Common Share.

REDEMPTION

     At any time prior to the close of business on the earlier of (i) the 
tenth day following the date (the "Shares Acquisition Date") of public 
announcement that an Acquiring Person has become such or such later date as 
may be determined by a majority of the Continuing Directors and publicly 
announced by the Company or (ii) the Final Expiration Date of the Rights, the 
Company may redeem the Rights in whole, but not in part, at a price of $0.01 
per Right ("Redemption Price"). 

NO SHAREHOLDERS' RIGHTS PRIOR TO EXERCISE

     Until a Right is exercised, the holder thereof, as such, will have no 
rights as a shareholder of the Company (other than any rights resulting from 
such holder's ownership of Common Shares), including, without limitation, the 
right to vote or to receive dividends.

AMENDMENT OF RIGHTS AGREEMENT

     The provisions of the Rights Agreement may be supplemented or amended by 
the Board of Directors in any manner prior to the Distribution Date without 
the approval of Rights holders. After the Distribution Date, the provisions 
of the Rights Agreement may be supplemented or amended by the Board in order 
to (i) cure any ambiguity, defect or inconsistency, (ii) to make changes 
which are deemed necessary or advisable and do not adversely affect the 
interests of holders of Rights (excluding the interests of any Acquiring 
Person), or to shorten or lengthen any time period under the Rights 
Agreement; provided, however, that no amendment to lengthen (A) the time 
period governing redemption shall be made at such time as the Rights are not 

                                       -6-

<PAGE>

redeemable, or (B) any other period unless for the purpose of protecting, 
enhancing or clarifying the rights of, and/or benefits to, the holders of 
Rights.

CERTAIN ANTI-TAKEOVER EFFECTS

     The Rights approved by the Board are designed to protect and maximize 
the value of the outstanding equity interests in the Company in the event of 
an unsolicited attempt by an acquiror to take over the Company, in a manner 
or on terms not approved by the Board of Directors. Takeover attempts 
frequently include coercive tactics to deprive a corporation's Board of 
Directors and its shareholders of any real opportunity to determine the 
destiny of the corporation. The Rights have been declared by the Board in 
order to deter such tactics, including a gradual accumulation of shares in 
the open market of a 20% or greater position to be followed by a merger or a 
partial or two-tier tender offer that does not treat all shareholders 
equally. These tactics unfairly pressure shareholders, squeeze them out of 
their investment without giving them any real choice and deprive them of the 
full value of their shares.

     The Rights are not intended to prevent a takeover of the Company and 
will not do so. The Rights are not exercisable in the event of a Permitted 
Offer, as described above. The Rights may be redeemed by the Company at 
$0.01 Right within ten days (or such later date as may be determined by a 
majority of the Continuing Directors) after the accumulation of 20% or more 
of the Company's outstanding Common Shares by a single acquiror or group.
Accordingly, the Rights should not preclude any merger or business 
combination approved by the Board of Directors. Issuance of the Rights does 
not in any way weaken the financial strength of the Company or interfere with 
its business plans. The issuance of the Rights has no immediate dilutive 
effect, will not affect reported earnings per share, should not be taxable to 
the Company or to its shareholders and will not change the way in which the 
Company's shares are presently traded. The Company's Board of Directors 
believes that the Rights represent a sound and reasonable means of addressing 
the complex issues of corporate policy created by the current takeover 
environment. However, the Rights may have the effect of rendering more 
difficult or discouraging an acquisition of the Company deemed undesirable by 
the Board of Directors. The 

                                       -7-

<PAGE>

Rights may cause substantial dilution to a person or group that attempts to 
acquire the Company on terms or in a manner not approved by the Company's 
Board of Directors, except pursuant to an offer conditioned upon the 
negation, purchase or redemption of the Rights.

Item 2.   EXHIBITS.

          1.* Preferred Shares Rights Agreement, dated as of August 21, 1996, 
              between Metra Biosystems, Inc. and The First National Bank of 
              Boston, including the Certificate of Determination of Rights, 
              Preferences and Privileges of Series A Participating Preferred 
              Stock, the form of Rights Certificate and the Summary of Rights 
              attached thereto as Exhibits A, B and C, respectively.

          2.  Amendment No. 1 to Preferred Shares Rights Agreement, dated as of 
              January 17, 1997, between Metra Biosystems, Inc. and The First 
              National Bank of Boston.
              
- -----------------------------------
*    Previously filed with Registrant's registration statement on Form 8-A, 
     filed with the Securities and Exchange Commission on August 22, 1996.

                                       -8-

<PAGE>

                                    SIGNATURE

     Pursuant to the requirements of Section 12 of the Securities Exchange 
Act of 1934, the registrant has duly caused this registration statement to be 
signed on its behalf by the undersigned, thereto duly authorized.

                                   METRA BIOSYSTEMS, INC.
                    
                    
Date: January 23, 1997             By /s/ KURT E. AMUNDSON       
                                      ------------------------------------------
                                      Vice President and Chief Financial Officer


                                       -9-

<PAGE>

                              METRA BIOSYSTEMS, INC.

                      REGISTRATION STATEMENT ON FORM 8-A/A

                                 EXHIBIT INDEX

                                                              Page Number Under
Exhibit                                                     Sequential Numbering
  No.                               Exhibit                         System
- -------                             -------                 --------------------

   1.*         Preferred Shares Rights Agreement, dated as  
               of August 21, 1996, between Metra Biosystems, 
               Inc. and The First National Bank of Boston,  
               including the Certificate of Determination of 
               Rights, Preferences and Privileges of Series A 
               Participating Preferred Stock, the form of 
               Rights Certificate and the Summary of Rights 
               attached thereto as Exhibits A, B and C, 
               respectively. 


   2.          Amendment No. 1 to Preferred Shares Rights 
               Agreement, dated as of January 17, 1997, 
               between Metra Biosystems, Inc. and The First 
               National Bank of Boston.




- -----------------------------------

*    Previously filed with Registrant's registration statement on Form 8-A, 
     filed with the Securities and Exchange Commission on August 22, 1996.

                                       -10-



<PAGE>







                             METRA BIOSYSTEMS, INC.

                                       and

                        THE FIRST NATIONAL BANK OF BOSTON

                                  Rights Agent










                               AMENDMENT NO. 1 TO 

                        PREFERRED SHARES RIGHTS AGREEMENT


                          Dated as of January 17, 1997



<PAGE>

                                  AMENDMENT NO. 1
                                         TO
                          PREFERRED SHARES RIGHTS AGREEMENT



     This Amendment No. 1 to Preferred Shares Rights Agreement, dated January 
17, 1997, amends that certain Preferred Shares Rights Agreement (the "Rights 
Agreement"), dated as of August 21, 1996 between Metra Biosystems, Inc., a 
California corporation (the "Company"), and The First National Bank of Boston 
(the "Rights Agent").

     On January 17, 1997, the Company's Board of Directors authorized an 
amendment of the Rights Agreement to increase certain threshold percentages 
required for a Person (as defined in the Rights Agreement) to become 
Acquiring Person (as defined in the Rights Agreement).

     NOW, THEREFORE, in consideration of the promises and the mutual 
agreements herein set forth, the parties hereby agree as follows:

     1.   Section 1(a) of the Rights Agreement is hereby amended and restated 
to read in full as follows:

          (a)  "Acquiring Person" shall mean any Person who or which, 
together with all Affiliates and Associates of such Person, shall be the 
Beneficial Owner of 20% or more of the Common Shares then outstanding, but 
shall not include the Company, any Subsidiary of the Company or any employee 
benefit plan of the Company or of any Subsidiary of the Company, or any 
entity holding Common Shares for or pursuant to the terms of any such plan. 
Notwithstanding the foregoing, no Person shall be deemed to be an Acquiring 
Person either (i) as the result of an acquisition of Common Shares by the 
Company which, by reducing the number of shares outstanding, increases the 
proportionate number of shares beneficially owned by such Person to 20% or 
more of the Common Shares of the Company then outstanding; PROVIDED, HOWEVER, 
that if a Person shall become the Beneficial Owner of 20% or more of the 
Common Shares of the Company then outstanding by reason of share purchases by 
the Company and shall, after such share purchases by the Company, become the 
Beneficial Owner of any additional Common Shares of the Company, then such 
Person shall be deemed to be an Acquiring Person; or (ii) if the Board of 
Directors of the Company determines in good faith that a Person who would 
otherwise be an "Acquiring Person" as defined pursuant to the foregoing 
provisions of this paragraph (a) has become such inadvertently, and such 
Person divests as promptly as practicable of a sufficient number of Common 
Shares so that such Person would no longer be an "Acquiring Person," as 
defined pursuant to the foregoing provisions of this paragraph (a).

     2.   Section 3(c) of the Rights Agreement is hereby amended and restated 
to read in full as follows:

          (c)  Unless the Board of Directors, by resolution adopted at or 
before the time of the issuance (including pursuant to the exercise of rights 
under the Company's benefit plans) of any Common Shares, specifies to the 
contrary, Rights shall be issued in respect of all Common 

                                       -1-

<PAGE>

Shares that are issued after the Record Date but prior to the earlier of the 
Distribution Date or the Expiration Date or, in certain circumstances 
provided in Section 22 hereof, after the Distribution Date. Certificates 
representing such Common Shares shall also be deemed to be certificates for 
Rights, and shall bear the following legend:

     This certificate also evidences and entitles the holder hereof to certain 
     rights as set forth in a Rights Agreement between Metra Biosystems, Inc. 
     and The First National Bank of Boston as the Rights Agent, dated as of 
     August 21, 1996, as amended (the "Rights Agreement"), the terms of which 
     are hereby incorporated herein by reference and a copy of which is on file 
     at the principal executive offices of Metra Biosystems, Inc. Under certain 
     circumstances, as set forth in the Rights Agreement, such Rights will be 
     evidenced by separate certificates and will no longer be evidenced by this 
     certificate. Metra Biosystems, Inc. will mail to the holder of this 
     certificate a copy of the Rights Agreement without charge after receipt of 
     a written request therefor. Under certain circumstances set forth in the 
     Rights Agreement, Rights issued to, or held by, any Person who is, was or 
     becomes an Acquiring Person or any Affiliate or Associate thereof (as such 
     terms are defined in the Rights Agreement), whether currently held by or on
     behalf of such Person or by any subsequent holder, may become null and 
     void.

With respect to such certificates containing the foregoing legend, until the 
earlier of (i) the Distribution Date or (ii) the Expiration Date, the Rights 
associated with the Common Shares represented by such certificates shall be 
evidenced by such certificates alone, and the surrender for transfer of any 
such certificate shall also constitute the transfer of the Rights associated 
with the Common Shares represented thereby. In the event that the Company 
purchases or acquires any Common Shares after the Record Date but prior to 
the Distribution Date, any Rights associated with such Common Shares shall be 
deemed canceled and retired so that the Company shall not be entitled to 
exercise any Rights associated with the Common Shares which are no longer 
outstanding.

     3.   All references in the Rights Agreement to the Rights Agreement 
shall be deemed to refer to the Rights Agreement, as amended hereby.

     4.   This Amendment may be executed in any number of counterparts and 
each of such counterparts shall for all purposes be deemed to be an original, 
and all such counterparts shall together constitute but one and the same 
instrument.

                                       -2-

<PAGE>

     IN WITNESS WHEREOF, the parties hereto have caused this Amendment No. 1 
to Preferred Shares Rights Agreement to be duly executed as of the day and 
year first above written.

                            METRA BIOSYSTEMS, INC.

                            By:    /S/ KURT E. AMUNDSON
                               -------------------------------------------------
                            Name:  Kurt E. Amundson
                                 -----------------------------------------------
                            Title: Chief Financial Officer
                                  ----------------------------------------------

                            THE FIRST NATIONAL BANK OF BOSTON

                            By:    /s/ KATHERINE S. ANDERSON
                               -------------------------------------------------
                            Name:  Katherine S. Anderson
                                 -----------------------------------------------
                            Title: Admin. Manager
                                  ----------------------------------------------

                                       -3-




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