DERMA SCIENCES INC
S-3, 1998-02-10
PHARMACEUTICAL PREPARATIONS
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    AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON FEBRUARY 10, 1998
                                                   REGISTRATION NO. 333-
================================================================================


                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                    FORM S-3

                             REGISTRATION STATEMENT
                                      UNDER
                           THE SECURITIES ACT OF 1933

                              DERMA SCIENCES, INC.
             (Exact name of Registrant as specified in its charter)

          Pennsylvania                                   23-2328753
  (State or other jurisdiction              (I.R.S. Employer Identification No.)
of incorporation or organization)

                         214 Carnegie Center, Suite 100
                               Princeton, NJ 08540
                                 (609) 514-4744
                   (Address, including zip code, and telephone
             number, including area code, of Registrant's principal
                               executive offices)

                           Edward J. Quilty, Chairman
                         214 Carnegie Center, Suite 100
                               Princeton, NJ 08540
                                 (609) 514-4744
            (Name, address, including zip code, and telephone number,
                   including area code, of agent for service)

                  Copies of all communications and notices to:
                          Raymond C. Hedger, Jr., Esq.
                                 Hedger & Hedger
                        1800 Linglestown Road, Suite 206
                              Harrisburg, PA 17110
                                 (717) 238-1800

         Approximate date of commencement of proposed sale to public:  From time
to time after this Registration Statement becomes effective.

         If the only securities  being registered on this Form are being offered
pursuant to dividend or interest  reinvestment plans, please check the following
box. [ ]

         If any of the  securities  being  registered  on  this  Form  are to be
offered  on a  delayed  or  continuous  basis  pursuant  to Rule 415  under  the
Securities Act of 1933,  other than  securities  offered only in connection with
dividend or interest reinvestment plans, check the following box [X]

         If this Form is filed to register additional securities for an offering
pursuant to rule 462(b) under the Securities Act, please check the following box
and list  the  Securities  Act  registration  statement  number  of the  earlier
effective registration statement for the same offering. [ ]

         If this  Form is a  post-effective  amendment  filed  pursuant  to rule
462(c) under the  Securities  Act,  please check the  following box and list the
Securities  Act  registration   statement   number  of  the  earlier   effective
registration statement for the same offering. [ ]

         If delivery of the  prospectus  is expected to be made pursuant to Rule
434, please check the following box. [ ]



<PAGE>


<TABLE>
<CAPTION>

                         CALCULATION OF REGISTRATION FEE
============================= ================== ====================== ====================== ======================
                                                   Proposed maximum       Proposed maximum
   Title of each class of       Amount to be      offering price per     aggregate offering          Amount of
securities to be registered      registered              unit                   price            registration fee
============================= ================== ====================== ====================== ======================
<S>                           <C>                <C>                    <C>                    <C>
Common Stock, $.01 par
value per share (1)               1,750,000            $1.19(2)               $2,082,500              $   706
- ----------------------------- ------------------ ---------------------- ---------------------- ----------------------
Common Stock, $.01 par
value per share (3)               1,750,000            $1.19(2)               $2,082,500              $   706
- ----------------------------- ------------------ ---------------------- ---------------------- ----------------------
Common Stock, $.01 par
value per share (4)                 250,000            $1.19(2)              $   297,500              $   101
- ----------------------------- ------------------ ---------------------- ---------------------- ----------------------

Totals                            3,750,000                                   $4,462,500               $1,513
============================= ================== ====================== ====================== ======================
</TABLE>

(1)  To be offered and sold by Selling  Shareholders upon conversion of Series A
     Preferred Stock (the "Preferred  Stock") into Common Stock,  $.01 par value
     per share (the "Common  Stock").  Pursuant to Rule 416 under the Securities
     Act, this registration statement also relates to an indeterminate number of
     additional  shares of Common Stock which may be issuable upon conversion of
     the Preferred Stock to prevent dilution resulting from stock splits,  stock
     dividends and similar transactions.
(2)  Estimated   solely  for  the  purpose  of  computing   the  amount  of  the
     registration fee in accordance with Rule 457(c) under the Securities Act of
     1933, as amended (the "Securities  Act"),  based on the average of the high
     and low sale  price  for the  Common  Stock  as  reported  by the  National
     Association of Securities Dealers Automated Quotation System-Small Cap
     Market on Feburary 6, 1998.
(3)  To be offered and sold by Selling Shareholders upon exercise of outstanding
     Warrants (the  "Warrants").  Pursuant to Rule 416 under the Securities Act,
     this  registration  statement  also relates to an  indeterminate  number of
     additional  shares of Common Stock which may be issuable  upon  exercise of
     the  Warrants  to  prevent  dilution  resulting  from stock  splits,  stock
     dividends and similar transactions.

(4)  To be offered and sold by Selling Shareholders.

         THE REGISTRANT HEREBY AMENDS THIS  REGISTRATION  STATEMENT ON SUCH DATE
OR DATES AS MAY BE NECESSARY TO DELAY ITS  EFFECTIVE  DATE UNTIL THE  REGISTRANT
SHALL FILE A FURTHER AMENDMENT WHICH SPECIFICALLY  STATES THAT THIS REGISTRATION
SHALL  THEREAFTER  BECOME  EFFECTIVE  IN  ACCORDANCE  WITH  SECTION  8(a) OF THE
SECURITIES  ACT OF  1933 OR  UNTIL  THIS  REGISTRATION  SHATEMENT  SHALL  BECOME
EFFECTIVE  ON SUCH  DATE  AS THE  SECURITIES  AND  EXCHANGE  COMMISSION,  ACTING
PURSUANT TO SAID SECTION 8(a), MAY DETERMINE.


<PAGE>

PROSPECTUS


                              DERMA SCIENCES, INC.

                               3,750,000 SHARES OF
                                  COMMON STOCK


         This  Prospectus  relates to 3,750,000  shares (the "Shares") of Common
Stock,  $.01 par value per share,  (the "Common Stock") of Derma Sciences,  Inc.
(the "Company") to be sold by certain  shareholders of the Company (the "Selling
Shareholders")  from  time to time.  In  addition,  pursuant  to Rule 416 of the
Securities Act of 1933, as amended,  (the "Securities Act") this Prospectus also
relates  to such  additional  number of shares  of  Common  Stock as may  become
issuable upon  conversion of the Company's  Series A Preferred  Stock,  $.01 par
value per share,  (the  "Preferred  Stock") or  exercise of warrants to purchase
shares of Common Stock (the  "Warrants")  as a result of,  among other  reasons,
stock splits, stock dividends and anti-dilution adjustments.

         The  Selling  Shareholders  may  sell  the  Shares  from  time  to time
directly,  through  agents,  broker-dealers  or  underwriters,  publicly  or  in
privately negotiated transactions, in one or more transactions,  including block
transactions,  on the Nasdaq Small Cap Market,  the Boston Stock  Exchange,  the
Pacific  Stock  Exchange or on any other  market or stock  exchange on which the
Shares may be listed in the future.  The  selling  price of the Shares may be at
market  prices  prevailing  at the  time of  sale,  at  prices  related  to such
prevailing market prices or at negotiated prices. See "Selling Shareholders" and
"Plan of Distribution."

         The Company will  receive no proceeds  from the resale of the Shares by
the  Selling  Shareholders.  However,  the  Company  will  receive  proceeds  of
$1,575,000  upon  the  exercise  of the  Warrants  if all  of the  Warrants  are
exercised.   The  Company  will  bear  all  expenses  in  connection   with  the
registration  of the  Shares  herein.  The  Selling  Shareholders  will  pay any
brokerage  compensation in connection  with its sale of the Shares.  The Company
has agreed to  indemnify  certain of the Selling  Shareholders  against  certain
civil liabilities,  including liabilities under the Securities Act. See "Selling
Shareholders" and "Plan of Distribution."

                              -------------------

         THE PURCHASE OF THESE  SECURITIES  INVOLVES A HIGH DEGREE OF RISK.  SEE
"RISK FACTORS" COMMENCING ON PAGE 4.

         THESE   SECURITIES  HAVE  NOT  BEEN  APPROVED  OR  DISAPPROVED  BY  THE
SECURITIES  AND  EXCHANGE  COMMISSION  NOR HAS THE  COMMISSION  PASSED  UPON THE
ACCURACY OR ADEQUACY OF THIS PROSPECTUS. ANY REPRESENTATION TO THE CONTRARY IS A
CRIMINAL OFFENSE.

         NO ONE HAS  BEEN  AUTHORIZED  TO GIVE  ANY  INFORMATION  OR TO MAKE ANY
REPRESENTATION  NOT CONTAINED OR INCORPORATED BY REFERENCE ON THIS PROSPECTUS IN
CONNECTION WITH THIS OFFERING.  ANY INFORMATION OR REPRESENTATION  NOT CONTAINED
OR  INCORPORATED  BY  REFERENCE  HEREIN  MUST NOT BE RELIED  ON AS  HAVING  BEEN
AUTHORIZED BY THE COMPANY OR ANY SELLING  SHAREHOLDER.  THIS PROSPECTUS DOES NOT
CONSTITUTE  AN  OFFER  TO  SELL  OR THE  SOLICITATION  OF AN  OFFER  TO BUY  THE
SECURITIES  OFFERED  HEREBY IN ANY STATE TO ANY PERSON TO WHOM IT IS UNLAWFUL TO
MAKE  SUCH  OFFER  OR  SOLICITATION.  EXCEPT  WHERE  OTHERWISE  INDICATED,  THIS
PROSPECTUS SPEAKS AS OF ITS DATE AND NEITHER THE DELIVERY OF THIS PROSPECTUS NOR
ANY SALE MADE HEREUNDER SHALL,  UNDER ANY  CIRCUMSTANCES,  CREATE AN IMPLICATION
THAT  THERE HAS BEEN NO  CHANGE IN THE  AFFAIRS  OF THE  COMPANY  SINCE THE DATE
HEREOF.

                              -------------------

         The  Company's  Common Stock is traded on the National  Association  of
Securities Dealers Automated Quotation System - SmallCap Market under the symbol
"DSCI".  On  February  9, 1998 the  closing  bid price for the  Common  Stock as
reported by Nasdaq SmallCap Market was $1.25.

                THE DATE OF THIS PROSPECTUS IS FEBRUARY 10, 1998.



<PAGE>



                             ADDITIONAL INFORMATION

         The Company has been subject to the  informational  requirements of the
Securities  Exchange Act of 1934, as amended,  (the  "Exchange  Act") since May,
1994,  and in accordance  therewith  files reports,  proxy  statements and other
information  with the Securities  and Exchange  Commission  (the  "Commission").
These  reports,  proxy  statements  and other  information  may be inspected and
copied at the  public  reference  facilities  maintained  by the  Commission  at
Judiciary Plaza, 450 Fifth Street, NW, Washington, DC 20549 and at the following
Regional Offices of the Commission:  7 World Trade Center, Suite 1300, New York,
New York 10048:  and  Citicorp  Center,  500 West  Madison  Street,  Suite 1400,
Chicago,  Illinois  60661-2511.  Reports  filed  since  April,  1996 can also be
inspected via the internet at http://www.sec.gov in the EDGAR archives.

         The Company has filed with the Commission a  registration  statement on
Form S-3 (the "Registration Statement") under the Securities Act with respect to
the  Shares  offered  hereby.  This  Prospectus  does  not  contain  all  of the
information  set  forth  in the  Registration  Statement  and the  exhibits  and
schedules thereto.  For further  information with respect to the Company and the
Shares offered hereby,  reference is hereby made to the Registration  Statement,
exhibits and schedules.

                 INCORPORATION OF CERTAIN DOCUMENTS BY REFERENCE

         The  documents  listed  below have been filed by the  Company  with the
Commission under the Exchange Act and are incorporated herein by reference:

         (a)      The Company's  Annual Report on Form 10-KSB for the year ended
                  December 31, 1996 (the "Form 10-KSB").

         (b)      The  Company's  Quarterly  Reports  on  Forms  10-QSB  for the
                  quarters  ended March,  31, 1997,  June 30, 1997 and September
                  30, 1997.

         (c)      The Company's  Current Reports on Forms 8-K filed May 6, 1997,
                  July 1, 1997 and November 24, 1997.

         (d)      The  Company's  definitive  Proxy  Statement  for the  Special
                  Meeting  of  Shareholders  held  January  7, 1998 (the  "Proxy
                  Statement").

         (e)      The description of the Company's Common Stock contained in the
                  Company's registration statement on Form 8-A effective May 13,
                  1994.

         (f)      The description of the Company's  Preferred Stock contained in
                  the Proxy Statement.

         All documents filed by the Company  pursuant to Sections 13(a),  13(c),
14 and 15(d) of the Exchange Act, subsequent to the date hereof and prior to the
filing  of a  post-effective  amendment  to  the  Registration  Statement  which
indicates  that all shares of Common  Stock  offered  hereby have been sold,  or
which  deregisters  all shares of Common Stock then remaining  unsold,  shall be
deemed to be  incorporated  by reference  into this  Prospectus and to be a part
hereof from the date of filing of such documents. Any statement contained herein
or in a document  incorporated or deemed to be incorporated by reference  herein
shall be deemed to be modified or superseded  for purposes of the  Prospectus to
the extent that such  statement  is modified or  superseded  by a statement in a
subsequently  filed  document which also is or is deemed to be  incorporated  by
reference  herein.  Any such  statement so modified or  superseded  shall not be
deemed,  except as so  modified  or  superseded,  to  constitute  a part of this
Prospectus.

         The Company will provide, without charge, to each person (including any
beneficial  owner) to whom this  Prospectus is  delivered,  upon written or oral
request by such person,  a copy of any and all of the information  that has been
incorporated  by reference in this  Prospectus  (not including  exhibits to such
information unless such exhibits are specifically incorporated by reference into
such  information).  Such requests should be directed to Richard S. Mink,  Chief
Operating Officer,  at the Company's principal executive offices at 214 Carnegie
Center, Suite 100, Princeton, New Jersey 08540, telephone (609) 514-4744.


                                       2

<PAGE>



                               PROSPECTUS SUMMARY

         The following summary is qualified in its entirety by the more detailed
information contained or incorporated by reference in this Prospectus.  Purchase
of  the  Shares   involves  a  high   degree  of  risk.   See  "Risk   Factors."


                                   THE COMPANY

         Derma  Sciences,  Inc. was  incorporated  under the laws of Colorado on
September 10, 1984. On June 3, 1996 the Company changed its state of domicile to
Pennsylvania. Its principal office is located at 214 Carnegie Center, Suite 100,
Princeton,  New Jersey,  08540.  Its  telephone  number is (609)  514-4744.  The
Company engages in the development,  marketing and sale of primarily proprietary
sprays,   ointments  and  dressings  for  the  management  of  certain   chronic
non-healing  skin  ulcerations  such as pressure,  diabetic  and venous  ulcers,
surgical incisions and burns. The Company markets its products, both directly to
customers  and through  independent  distributors,  primarily  to the  geriatric
community such as nursing homes, similar extended care facilities, hospitals and
home  healthcare  agencies  throughout  the  United  States.  In  addition,  the
Company's  products  are  available  in selected  markets  throughout  the world
through strategic alliances with local companies.


                                  THE OFFERING

         Securities Offered. This Prospectus relates to the offer and sale of up
to 3,750,000 shares of Common Stock of the Company (the "Shares") by the Selling
Shareholders.  The  Shares  are  held  by,  or  are  issuable  to,  the  Selling
Shareholders as follows: (i) 1,750,000 of the Shares are issuable to the Selling
Shareholders  upon  conversion  of the Preferred  Stock into Common Stock;  (ii)
1,750,000 of the Shares are issuable to the Selling  Shareholders  upon exercise
of the Warrants; and (iii) 250,000 of the Shares are currently held by the Galen
Partners III partnerships. See "Selling Shareholders."
 
         Securities  Outstanding.  The  Company  has  the  following  securities
outstanding:

         Common Stock  (1).................................   4,567,635 shares
         Series A Convertible Preferred Stock (2) .........   1,750,000 shares
         Warrants to purchase Common Stock (3).............   1,750,000
         Warrants to purchase Common Stock (4).............      50,000
         Options to purchase Common Stock (5)..............   1,171,000
                    
(1)      Common Stock, $.01 par value per share, authorized: 15,000,000 shares.
(2)      Series A  Convertible  Preferred  Stock,  $.01  par  value  per  share,
         authorized:  1,750,000  shares.  Each  share of  Series  A  Convertible
         Preferred  Stock is  convertible  into Common  Stock,  on a one for one
         basis and without limitation, at the option of the holder thereof.
(3)      Each  Warrant  entitles  the holder  thereof to  purchase  one share of
         Common Stock,  at a price of $.90 per share,  at any time prior to 3:30
         p.m. EST November 15, 2001.
(4)      Each  Warrant  entitles  the holder  thereof to  purchase  one share of
         Common  Stock,  at a price of $3.125  per  share,  at any time prior to
         August 2, 2001.
(5)      These Options entitle the holders thereof to purchase a total 1,171,000
         shares of Common Stock at prices  ranging from $.80 to $2.50 per share.
         These  options vest at varying rates and expire at various dates during
         the period January 1, 2007 through January 29, 2008.

         Use of Proceeds.  The Company  will not receive any  proceeds  from the
sale  of the  Common  Stock  sold  by the  Selling  Shareholders.  If all of the
Warrants are  exercised,  the Company will receive gross proceeds of $1,575,000.
The Company  intends to utilize any proceeds  received  from the exercise of the
Warrants for general corporate purposes.

         Risk Factors. See "Risk Factors" for a discussion of certain risks that
should be considered by prospective  investors in connection  with an investment
in the Shares.




                                       3

<PAGE>


                           FORWARD LOOKING STATEMENTS

         Statements  contained in this  Prospectus,  including  the  information
incorporated herein by reference, that are not statements of historical fact may
be deemed to be forward-looking  statements.  Without limiting the generality of
the foregoing,  words such as "may," "will," "expect," "believe,"  "anticipate,"
"intend,"   "could,"   "estimate"  or   "continue"   are  intended  to  identify
forward-looking  statements. The Company cautions readers that certain important
factors may affect the Company's  actual results and could cause such results to
differ materially from any forward-looking  statements which may be made in this
Prospectus or which are otherwise  made by or on behalf of the Company.  Factors
which may affect the Company's results include,  but are not limited to, product
demand,  market acceptance,  impact of competitive products and prices,  product
development,  commercialization or technological  difficulties and trade, legal,
social and economic risks.  The Company is also subject to other risks discussed
in the  Company's  Commission  filings.  Additional  factors that could cause or
contribute  to  differences  between the  Company's  actual  results and forward
looking  statements  include,  but are not limited to, those  discussed in "Risk
Factors"  below as well as elsewhere  in this  Prospectus  and in the  Company's
filings with the Commission.

                                  RISK FACTORS

         AN  INVESTMENT  IN THE  SECURITIES  OFFERED  HEREBY IS  SPECULATIVE  IN
NATURE,  INVOLVES  A HIGH  DEGREE  OF RISK  AND  SHOULD  ONLY BE  CONSIDERED  BY
INVESTORS  WHO CAN AFFORD TO LOSE THEIR  ENTIRE  INVESTMENT.  IN ADDITION TO THE
OTHER  INFORMATION  CONTAINED IN THIS  PROSPECTUS,  THE  FOLLOWING  RISK FACTORS
SHOULD BE CONSIDERED CAREFULLY IN EVALUATING WHETHER TO MAKE AN INVESTMENT.

         No Dividends. The Company has not paid any cash dividends on its Common
Stock to date. Payment of dividends on the Common Stock is within the discretion
of the Board of  Directors  and will depend  upon the  Company's  earnings,  its
capital  requirements and financial  condition,  and other relevant factors. The
Company  does  not  intend  to  declare  dividends  on its  Common  Stock in the
foreseeable future.

         Outstanding  Options.  The Company has issued  options to purchase  its
Common Stock to current and former  members of its board of  directors,  current
and former  executive  officers  and  certain  outside  consultants.  Presently,
options to purchase  1,171,000  shares of Common  Stock,  at per share  exercise
prices  ranging  from $.80 to $2.50,  are  outstanding.  The  exercise  of these
options  could  have a  dilutive  effect  on  ownership  interests  of  existing
shareholders as well as investors in this Offering.

         Possible  Volatility  of  Securities  Prices.  The market  price of the
Common  Stock  has in the  past  been,  and may in the  future  continue  to be,
volatile.  A variety of events,  including  quarter  to  quarter  variations  in
operating results, news announcements or the introduction of new products by the
Company  or its  competitors,  as well as market  conditions  in the wound  care
industry or changes in earnings estimates by securities analysts,  may cause the
market price of the Common Stock to fluctuate  significantly.  In addition,  the
stock  market  in recent  years has  experienced  significant  price and  volume
fluctuations  which have  affected  market  prices of equity  securities of many
companies and which often have been  unrelated to the operating  performance  of
such companies.  These market fluctuations may adversely affect the price of the
Common Stock.

         Absence  of  Historical  Profitability;   Recent  Losses;   Accumulated
Deficit.  The Company had limited  profitability in the years ended December 31,
1994  and 1995  and  incurred  a loss in the year  ended  December  31,  1996 of
$1,436,265. The Company anticipates a loss in excess of $2.4 million (unaudited)
with an accumulated deficit of in excess of $4.0 million (unaudited) in the year
ended December 31, 1997. The Company's revenues are derived solely from sales of
its wound care  products.  Inasmuch as the Company will  continue to have a high
level  of  operating   expense,   the  Company's   ability  to  achieve   future
profitability will depend upon its ability to attain corresponding  increases in
revenues.

         Quarterly Fluctuations.  The Company's quarterly revenues and operating
results have varied  significantly  in the past and may continue to do so in the
future.  In  particular,  the  Company's  distributors  and other  customers may
purchase several months of inventory at one time which may cause fluctuations in
quarterly  revenues.  Future  revenues and operating  results may also fluctuate
significantly from quarter to quarter and will depend upon, among other factors:
(i) demand for the  Company's  products  and new  product  introductions  by the


                                       4
<PAGE>


Company or its  competitors or  transitions to new products,  (ii) the timing of
orders and shipments, (iii) the mix of sales between products, (iv) competition,
including  pricing  pressures,  (v) the  timing of  regulatory  and  third-party
reimbursement  approvals,  and (vi)  the  timing  of  research  and  development
expenditures.   Accordingly,   period-to-period  comparisons  of  the  Company's
revenues and  operating  results  should not be relied upon as an  indication of
future performance and the results of any quarterly period may not be indicative
or results to be expected for a full year.

         Restructuring  of  Distribution  System.  The Company is engaged in the
restructuring  of its product  distribution  system pursuant to which certain of
the Company's former master  distributors  will be supplemented or replaced by a
direct sales force  employed by the Company.  There can be no assurance that the
Company will be able to continue to successfully  expand its sales and marketing
staff,  that such an expanded sales and marketing staff will be  cost-effective,
or that the  Company's  increased  direct  sales and  marketing  efforts will be
successful.   The  Company  also  sells  its  products   through   international
distributors of medical products.  There can be no assurance that the Company or
its  distributors  will be  successful  in  marketing  or selling the  Company's
products.

         Ability to Renew  Present  Financing.  The Company has a line of credit
arrangement  with PNC Bank (the "Bank") in a maximum  amount of $800,000.  As of
January 30, 1998 the Company had  borrowed  $689,000  under this line of credit.
The line of credit  matures  March 31,  1998.  Although in the past the Bank has
renewed the Company's  line of credit upon  maturity,  there can be no assurance
that it will  continue  to do so. If the Bank does not renew the line of credit,
there can be no assurance  that the Company will be able to arrange  alternative
financing on terms satisfactory to it.

         Government   Regulation   and  Product   Approval.   The   development,
manufacturing  and marketing of the Company's  products are subject to extensive
and  rigorous  regulation  by numerous  governmental  authorities  in the United
States and other  countries.  The  marketing  and sale of products  may not take
place in the United States absent compliance with applicable  regulations of the
United  States Food and Drug  Administration  ("FDA").  The  manufacture  of the
products must be in  accordance  with  standards  set by the Good  Manufacturing
Practice ("GMP") regulations.

         In the future,  government  regulations may be promulgated  which could
delay  regulatory  approval  of the  Company's  products.  Adverse  governmental
regulation which might arise from future  legislative or  administrative  action
cannot  be  predicted.  There  can  be no  assurance  that  additional  products
developed  by the  Company,  alone  or in  collaboration  with  others,  will be
determined  to be safe  and  efficacious  or meet  other  applicable  regulatory
standards.  Even if such approvals are obtained,  post-market  evaluation of the
products,  if required,  could result in  suspension or limitation of approvals.
Delays in  obtaining  U.S.  or  foreign  approvals  could  adversely  affect the
marketing of the Company's products.

         Declining  Sales and Dependence on a Single Product Line. The Company's
revenues are  principally  derived from the sale of its wound care products.  If
the market for wound care products were to decline for any reason, the Company's
results of operations would be adversely affected.  The Company's sales declined
in 1996 by $1,166,647,  or 20%, to $4,557,931 from $5,724,578 in 1995. Sales for
1997 declined by approximately  $548,000,  or 12%, to  approximately  $4,000,000
(unaudited).

         Healthcare Reimbursement. The Company's ability to sell its products in
certain  areas  depends in part upon the  extent to which a consumer  is able to
obtain  reimbursement  for the cost of the Company's  products  from  government
health  administration  authorities,  private health coverage insurers and other
organizations.  Uncertainty  exists  as to the  future  reimbursement  status of
healthcare products such as those sold by the Company.

         Government  and other  third  party  payors are  attempting  to contain
healthcare  costs by limiting both coverage and the level of  reimbursement  for
healthcare products.  Whereas federal and state governments,  as well as private
insurers,  will  continue to pursue  programs  designed to control or reduce the
cost of health care, there can be no assurance as to whether, or to what extent,
reimbursements for the Company's products will continue to be available.

         Patents and Proprietary Technology. The Company has been awarded a U.S.
patent and several foreign patents  relative to its Dermagran  Spray,  Dermagran
Ointment,  Dermagran  II  Moisturizing  Spray and  Dermagran  II  Ointment.  The
Company's  success may  depend,  in part,  on its  ability to obtain  additional


                                       5

<PAGE>


patents,  maintain trade secret protection and operate without infringing on the
proprietary rights of third parties.  There can be no assurance that the Company
will develop  additional  proprietary  products  that are  patentable,  that any
patents issued to the Company or its licensors will provide the Company with any
competitive  advantages or will not be challenged by third parties,  or that the
patents of others will not have an adverse  effect on the ability of the Company
to do  business.  Furthermore,  there can be no  assurance  that others will not
independently develop similar products,  duplicate any of the Company's products
or design around the patented products developed by the Company.

         Dependence on Third Party Manufacturers. The Company currently does not
have the capability to manufacture  products and does not intend to develop such
capabilities  in the  foreseeable  future.  The Company  believes that there are
numerous available  manufacturers for its products.  However,  if the Company is
unable to obtain or retain third party manufacturing on commercially  acceptable
terms, it may be delayed in its ability to commercialize  products or may not be
able to commercialize  products as planned.  The Company's dependence upon third
parties for the  manufacture  of products  may  adversely  affect the  Company's
profit  margins and its ability to develop and deliver  products on a timely and
competitive basis.

         Technological Change and Competition. The Company operates in a rapidly
evolving  field and new  developments  are expected to continue at a rapid pace.
Competition from large pharmaceutical companies,  biotechnology companies, joint
ventures,  research  and  academic  institutions  and others is intense  and may
increase.  Many of these companies and institutions have  substantially  greater
capital  resources,  research and  development  staffs and  facilities  than the
Company and substantially  greater experience in obtaining  regulatory approvals
and manufacturing and marketing pharmaceutical products. The activities of these
entities  represent  significant  long-term  competition  for  the  Company.  In
addition,  the Company's competitors may succeed in developing  technologies and
products  that are more  effective  than any  that are  being  developed  by the
Company or that would  otherwise  render the Company's  technology  and products
obsolete or noncompetitive.

         Attraction  and  Retention  of  Key  Personnel.  The  Company's  future
performance  depends in  significant  measure upon the continued  service of its
senior  management  and upon its  ability to attract and retain  highly  skilled
managerial,  marketing and sales  personnel.  The Company faces  competition for
such  personnel  from other  companies  in its  industry,  research and academic
institutions,  government  entities  and other  organizations.  By virtue of the
Company's  small size and limited  resources  relative to other companies in its
industries,  there can be no assurance that the Company will continue to be able
to attract  and retain  the  personnel  required  to achieve  profitability  and
growth.

         Product  Liability;  Insurance.  The commercial sale of pharmaceuticals
may expose the Company to liability  claims  incident to alleged adverse effects
caused by these  products.  These  claims might be made  directly by  consumers,
distributors,  wholesalers,  dealers or others selling the products. The Company
has obtained $1,000,000 per occurrence,  $2,000,000 aggregate, product liability
insurance.  However, such coverage is becoming increasingly  expensive and there
is no assurance  that  liability  insurance  will  continue to be available at a
reasonable  cost or that  such  insurance  is, or will be,  sufficient  to cover
claims.

         Control  by  Existing  Management  and  Shareholders.   Following  this
Offering,  and assuming  exercise of all of the Warrants,  the Company's current
shareholders, directors and executive officers will continue to have the ability
to elect all of the Company's  directors and determine corporate and shareholder
actions.


                                       6

<PAGE>


                                 USE OF PROCEEDS

         The Company will not receive any  proceeds  from the sale of the Shares
offered by the Selling Shareholders.  If all of the Warrants are exercised,  the
Company  will  receive  gross  proceeds of  $1,575,000.  The Company  intends to
utilize any  proceeds  received  from the  exercise of the  Warrants for general
corporate  purposes.  There can be no assurance that any of the Warrants will be
exercised.

                              SELLING SHAREHOLDERS

         The  following  table  sets  forth  as of the  date of this  Prospectus
certain information with respect to the Shares held by the Selling Shareholders.
The Company believes that all Selling Shareholders named herein have sole voting
and  investment  power with  respect to all  Shares  beneficially  owned by them
subject,   where   applicable,   to  community   property  laws.   Each  Selling
Shareholder's ownership is determined by assuming that all Warrants held by such
Selling Shareholder have been exercised.  Each Selling  Shareholder's  ownership
after the Offering is determined  by assuming that all of the Shares  registered
for the account for the Selling Shareholder are sold. No Selling Shareholder has
had any position, office or other material relationship with the Company, or any
of its  affiliates,  during the past three  years  other than as a holder of the
Company's Common Stock.

<TABLE>
<CAPTION>



                                                                      SHARES          SHARES      SHARES TO BE
                                                                   BENEFICIALLY       OFFERED      OWNED AFTER
                                   NAME                               OWNED           HEREBY         OFFERING
                                ----------                         ------------      ---------    ------------
<S>                                                                <C>              <C>              <C>
           The Aries Fund, a Cayman Islands Trust...............     502,500           502,500        - 0 -
           Aries Domestic Fund, L.P.............................     247,500           247,500        - 0 -
           Steven A. Elms.......................................      25,000            25,000        - 0 -
           Kristin L. Enghauser.................................      12,500            12,500        - 0 -
           Galen Employee Fund III, L.P.........................       4,549             4,549        - 0 -
           Galen Partners III, L.P..............................     888,795           888,795        - 0 -
           Galen Partners International III, L.P................     106,656           106,656        - 0 -
           David Golden.........................................      25,000            25,000        - 0 -
           Hambrecht & Quist California.........................   1,225,000         1,225,000        - 0 -
           Vivek Jain...........................................      62,500            62,500        - 0 -
           Russell L. Pollack...................................      25,000            25,000        - 0 -
           Dennis J. Purcell....................................     125,000           125,000        - 0 -
           Redwood Asset Management.............................     500,000           500,000        - 0 -
                                                                   ---------         ---------
               Total............................................   3,750,000         3,750,000
</TABLE>

                              PLAN OF DISTRIBUTION

         The Shares set forth in the "Selling Shareholders" table may be sold by
the  Selling  Shareholders,   or  by  pledgees,  donees,  transferees  or  other
successors in interest,  either pursuant to the Registration  Statement of which
this  Prospectus  forms a part  or,  if  available,  under  Section  4(1) of the
Securities Act or Rule 144 promulgated  thereunder.  To the Company's knowledge,
this Offering is not being  underwritten.  The Company believes that the Selling
Shareholders,  directly  or  through  agents  designated  from time to time,  or
through  broker-dealers  or underwriters also to be designated (who may purchase
as principal and resell for their own account), may sell the Shares from time to
time, publicly or through privately negotiated  transactions,  or in one or more
transactions,  including block transactions,  on the Nasdaq SmallCap Market, the
Boston  Stock  Exchange,  the Pacific  Stock  Exchange or on any other market or
stock exchange on which the Shares may be listed in the future.

         The selling price of the Shares may be at market  prices  prevailing at
the time of sale,  at prices  relating to such  prevailing  market  prices or at
negotiated  prices.  From time to time the  Selling  Shareholders  may engage in
short sales against the box, puts and calls and other transactions in securities
of the Company or  derivatives  thereof,  and may sell and deliver the shares in
connection therewith. Further, the Selling Shareholders are not restricted as to
the number of shares  which may be sold at any one time.  It is possible  that a
significant  number  of shares  could be sold at the same time  which may have a
depressive effect on the market price of the Company's Common Stock.


                                       7

<PAGE>



         The Selling  Shareholders  may also  pledge  shares as  collateral  for
margin  accounts,  and such shares could be resold pursuant to the terms of such
accounts.  Resales or reoffers of the Shares by the Selling Shareholders must be
accompanied  by a copy of this  Prospectus.  The  Selling  Shareholders  and any
agents,  broker-dealers  or underwriters that participate in the distribution of
the Shares may be deemed to be  underwriters,  and any profit on the sale of the
Shares by them, and any discounts,  commissions or concessions received by them,
may be deemed to be  underwriting  commissions or discounts under the Securities
Act.

                                MATERIAL CHANGES

         Amendment  of  Articles of  Incorporation.  The  Company's  articles of
incorporation were amended on February 6, 1998 pursuant to shareholder  approval
granted at a special meeting of the Company's shareholders held January 7, 1998.
The  amendment  authorizes  the Company to issue  1,750,000  shares of preferred
stock "with such  designations,  voting  rights,  preferences,  limitations  and
special rights as the board of directors may direct."  Acting in accordance with
the foregoing authority, the board of directors, by resolution dated February 9,
1998,  designated all 1,750,000  shares of the Company's  preferred stock as its
Series A Convertible Preferred Stock (the "Preferred Stock") and further defined
the rights and preferences of the Preferred Stock.  These rights and preferences
are described in the  Company's  Current  Report on Form 8-K filed  November 19,
1997 and in the Company's Proxy Statement  incorporated by reference herein. The
Shares to which this Prospectus relates include 1,750,000 Shares of Common Stock
issuable upon conversion of the Preferred Stock.

         Fourth  Quarter 1997  Operating  Loss.  During the fourth quarter ended
December  31,  1997 the  Company  incurred an  operating  loss of  approximately
$200,000 (unaudited).

                                  LEGAL MATTERS

         Matters relating to the legality of the securities being offered hereby
are being passed upon for the Company by Hedger & Hedger, 1800 Linglestown Road,
Suite 206, Harrisburg, Pennsylvania, 17110.

                                     EXPERTS

         The  financial  statements  of the Company  appearing in the  Company's
Annual  Report  (Form  10-KSB)  for the year ended  December  31, 1996 have been
audited by Ernst & Young LLP, independent auditors, as set forth in their report
thereon included therein and  incorporated  herein by reference.  Such financial
statements  are  incorporated  herein by reference in reliance  upon such report
given upon the authority of such firm as experts in accounting and auditing.












                                       8
<PAGE>




                                     PART II

                     INFORMATION NOT REQUIRED IN PROSPECTUS

ITEM 14.  OTHER EXPENSES OF ISSUANCE AND DISTRIBUTION.

         The  following  table sets  forth  expenses  (estimated  except for the
registration fee) in connection with the Offering  described in the Registration
Statement:

         SEC registration fee .........................       $  1,513
         Accounting fees and expenses .................          5,000
         Legal fees and expenses ......................         15,000
         Printing expenses ............................          2,500
         Miscellaneous ................................          1,000
                                                               -------

             Total ....................................        $25,013
                                                               =======


ITEM 15.  INDEMNIFICATION OF DIRECTORS AND OFFICERS.

         Sections 1741 and 1742 of the Pennsylvania  Business Corporation Law of
1988  empower the Company,  and the bylaws of the Company  provide that it shall
have the power,  to indemnify  any person who was or is a party or is threatened
to be made a party to any  threatened,  pending  or  completed  action,  suit or
proceeding by reason of the fact that he is or was a director, officer, employee
or agent of the Company, or is or was serving at the request of the Company as a
director, officer, employee or agent of another corporation,  partnership, joint
venture,  trust or other  enterprise,  against  expenses,  judgments,  fines and
amounts paid in settlement actually and reasonably incurred by him in connection
with such action,  suit or  proceeding if he acted in good faith and in a manner
he reasonably believed to be in, or in the case of actions undertaken other than
in his official capacity, not opposed to, the best interest of the Company, and,
with respect to any criminal  action or proceeding,  had no reasonable  cause to
believe his conduct was unlawful;  except that, in the case of an action or suit
by or in the right of the Company,  no indemnification may be made in respect of
any claim,  issue or matter as to which such person shall have been  adjudged to
be liable for  negligence or misconduct  in the  performance  of his duty to the
Company  unless  and only to the extent  that the court in which such  action or
suit was  brought  shall  determine  that such  person is fairly and  reasonably
entitled to indemnity for proper expenses.

ITEM 16.  EXHIBITS.

         Exhibit Number         Description
         --------------         -----------
         5 ................     Opinion of Hedger & Hedger regarding the
                                  legality of the securities being registered
         23.1 .............     Consent of Ernst & Young LLP
         23.2 .............     Consent of Hedger & Hedger (included in its
                                  opinion filed as Exhibit 5)
         24 ...............     Powers of Attorney (included in signature page
                                  forming a part hereof)


ITEM 17.  UNDERTAKINGS.

         The undersigned Registrant hereby undertakes:

         (l) To file, during any period in which offers or sales are being made,
a post-effective amendment to this Registration Statement:

                  (i) To include any prospectus  required by Section 10(a)(3) of
         the Securities Act of 1933;

                  (ii) To reflect in the  prospectus any facts or events arising
         after the  effective  date of the  Registration  Statement (or the most
         recent post-effective amendment thereof) which,  individually or in the
         aggregate,  represent a fundamental change in the information set forth
         in the  Registration  Statement;  notwithstanding  the  foregoing,  any
         increase  or  decrease  in volume of  securities  offered (if the total
         dollar value of the securities  offered would not exceed that which was
         registered) and any deviation from the low or high end of the estimated


                                      II-1
<PAGE>



         maximum offering range may be reflected in the form of prospectus filed
         with the Commission  pursuant to Rule 424(b) if, in the aggregate,  the
         changes in volume and price  represent no more than a 20 percent change
         in the maximum  aggregate  offering price set forth in the "Calculation
         of Registration Fee" table in the effective Registration Statement; and

                  (iii) To include any material  information with respect to the
         plan of  distribution  not  previously  disclosed  in the  Registration
         Statement  or  any  material   change  to  such   information   in  the
         Registration Statement;  provided,  however, that paragraphs (l)(i) and
         (l)(ii) do not apply if the  Registration  Statement  is on Form S-3 or
         Form  S-8,   and  the   information   required  to  be  included  in  a
         post-effective  amendment by those  paragraphs is contained in periodic
         reports filed by the registrant  pursuant to Section 13 or 15(d) of the
         Securities  Exchange Act of 1934 that are  incorporated by reference in
         the Registration Statement.

         (2) That,  for the  purpose  of  determining  any  liability  under the
Securities Act of 1933, each such post-effective amendment shall be deemed to be
a new Registration Statement relating to the securities offered therein, and the
offering of such  securities at that time shall be deemed to be the initial bona
fide offering thereof.

         (3) To remove from registration by means of a post-effective  amendment
any of the securities being registered which remain unsold at the termination of
the offering.

         (4)  That,  for  purposes  of  determining   any  liability  under  the
Securities  Act of 1933,  as  amended,  each filing of the  Registrant's  annual
report pursuant to Section 13(a) or 15(d) of the Securities Exchange Act of 1934
that is incorporated by reference in the Registration  Statement shall be deemed
to be a new Registration  Statement  relating to the securities offered therein,
and the  offering  of such  securities  at that  time  shall be deemed to be the
initial bona fide offering thereof.

         Insofar as indemnification for liabilities arising under the Securities
Act of 1933 may be permitted to directors,  officers and controlling  persons of
the Registrant  pursuant to the  provisions  described  under Item 15 above,  or
otherwise, the Registrant has been advised that in the opinion of the Securities
and  Exchange  Commission  such  indemnification  is  against  public  policy as
expressed in the Act and is, therefore, unenforceable. In the event that a claim
for  indemnification  against  such  liabilities  (other than the payment by the
Registrant of expenses  incurred or paid by a director,  officer or  controlling
person of the  Registrant  in the  successful  defense  of any  action,  suit or
proceeding)  is  asserted by such  director,  officer or  controlling  person in
connection with the securities being registered,  the Registrant will, unless in
the opinion of its counsel the matter has been settled by controlling precedent,
submit  to a  court  of  appropriate  jurisdiction  the  question  whether  such
indemnification  by it is against public policy as expressed in the Act and will
be governed by the final adjudication of such issue.



                                      II-2

<PAGE>


                                   SIGNATURES

         Pursuant  to the  requirements  of the  Securities  Act  of  1933,  the
Registrant certifies that it has reasonable grounds to believe that it meets all
of the requirements for filing on Form S-3 and has duly caused this Registration
Statement  to be  signed  on its  behalf  by  the  undersigned,  thereunto  duly
authorized,  in the City of  Princeton,  State of New Jersey,  on the 9th day of
February 1998.

                                     DERMA SCIENCES, INC.



                                     By:  /s/ Edward J. Quilty
                                        ------------------------------------
                     Edward J. Quilty, Chairman of the Board

                                POWER OF ATTORNEY

         Know  all men by these  presents,  that  each  person  whose  signature
appears below  constitutes  and appoints Edward J. Quilty as his true and lawful
attorney-in-fact  and agent, with full power of substitution and  resubstitution
for him and in his name,  place and stead, in any and all capacities to sign any
and all amendments  (including  post-effective  amendments) to this Registration
Statement,  and to file the same, with all exhibits thereto, and other documents
in connection  therewith with the Securities and Exchange  Commission,  granting
unto said  attorney-in-fact and agent full power and authority to do and perform
each and every act and thing  requisite or necessary to be done in and about the
premises,  as  fully  to all  intents  and  purposes  as he might or could do in
person, hereby ratifying and confirming all that said attorney-in-fact and agent
or his substitute or substitutes,  may lawfully do or cause to be done by virtue
hereof.

         Pursuant  to the  requirements  of the  Securities  Act of  1933,  this
Registration  Statement  has been signed below by the  following  persons in the
capacities and on the dates indicated.

    SIGNATURE                CAPACITY IN WHICH SIGNED                DATE


/s/ Edward J. Quilty
- --------------------       Chairman of the Board and Director  February 9, 1998
Edward J. Quilty             (Principal Executive Officer)


/s/ Richard S. Mink
- --------------------       Chief Operating Officer             February 9, 1998
Richard S. Mink


/s/ Stephen T. Wills
- --------------------       Vice President and Chief Financial  February 9, 1998
Stephen T. Wills, CPA, MST   Officer (Principal Financial and
                             Accounting Officer)


/s/ John T. Borthwick
- --------------------       Director                            February 9, 1998
John T. Borthwick


/s/ Mary G. Clark
- --------------------       Director                            February 9, 1998
Mary G. Clark


/s/ Laurence F. Lane
- --------------------       Director                            February 9, 1998
Laurence F. Lane






                                      II-3





February 10, 1998




The Board of Directors
Derma Sciences, Inc.
214 Carnegie Center, Suite 100
Princeton, NJ 08540

Re:  Registration Statement on Form S-3

Gentlemen and Madam:

We are counsel to Derma  Sciences,  Inc. (the  "Company") in connection with the
Registration Statement on Form S-3 filed on February 10, 1998 (the "Registration
Statement") under the Securities Act of 1933, as amended, covering the resale by
certain of the Company's shareholders of up to 3,750,000 shares of the Company's
Common  Stock,  par value  $.01 per  share  (the  "Shares"),  which  shares  are
currently  issued or to be issued  pursuant to the  conversion  of the Company's
Series A Convertible Preferred Stock (the "Preferred Stock") and the exercise of
Warrants to purchase the Company's Common Stock (the "Warrants").

We have examined the originals, or certified,  conformed or reproduction copies,
of such  records,  agreements,  instruments  and  documents  as we  have  deemed
relevant or necessary as the basis for the opinion hereinafter expressed. In all
such examinations, we have assumed the genuineness of all signatures on original
or certified  copies and the  conformity to original or certified  copies of all
copies  submitted  to us as  conformed  or  reproduction  copies.  As to various
questions of fact relevant to our opinion,  we have relied upon, and assumed the
accuracy of,  certificates and oral or written  statements and other information
of or from  public  officials,  officers or  representatives  of the Company and
others.

Based upon the  foregoing,  we are of the  opinion  that the  Shares,  including
therein those issued and to be issued upon conversion of the Preferred Stock and
exercise of the Warrants, are, or will be, as applicable,  validly issued, fully
paid and non-assessable shares of Common Stock of the Company.



<PAGE>


Derma Sciences, Inc.
February 10, 1998
Page 2




We  hereby  consent  to  the  filing  of  this  opinion  as an  exhibit  to  the
Registration  Statement  and to the  reference  to this firm  under the  caption
"Legal Opinion" in the Prospectus forming a part of the Registration Statement.

Very truly yours,

HEDGER & HEDGER



Raymond C. Hedger, Jr.




Consent of Independent Auditors

We  consent to the  reference  to out firm under the  caption  "Experts"  in the
Registration  Statement (Form S-3 No. 333-0000) and related  Prospectus of Derma
Sciences,  Inc. for the registration of 3,750,000 shares of its common stock and
to the  incorporation by reference therein of our report dated January 17, 1997,
with respect to the financial statements of Derma Sciences, Inc. included in its
Annual Report (Form 10-KSB) for the year ended December 31, 1996, filed with the
Securities and Exchange Commission.




                                                     /s/ ERNST & YOUNG LLP

Philadelphia, Pennsylvaina
February 10, 1998




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