BIOTECHNOLOGY INVESTMENTS LTD
SC 13G, 1998-02-06
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                    SECURITIES AND EXCHANGE COMMISSION
                          Washington, D.C.  20549


                         ________________________


                               SCHEDULE 13G

          Information Statement pursuant to Rules 13d-1 and 13d-2
                 Under the Securities Exchange Act of 1934

                            (Amendment No.   )


              Vista Medical Technologies, Inc.                   
_________________________________________________________________
                             (Name of Issuer)


                  Common Stock, $.01 par value                   
_________________________________________________________________
                      (Title of Class of Securities)



                          0009283691                             
_________________________________________________________________
                              (CUSIP Number)













                         ________________________
<PAGE>
CUSIP No. 0009283691                                      Page 2 of 7 Pages

_________________________________________________________________
1)   Name of Reporting Person                 Biotechnology
     S.S. or I.R.S. Identification            Investments
     No. of Above Person                      Limited
_________________________________________________________________
2)   Check the Appropriate Box                  (a) [   ]
     if a Member of a Group                     (b) [   ]
_________________________________________________________________
3)   SEC Use Only
_________________________________________________________________
4)   Citizenship or Place                     Guernsey,
     of Organization                          Channel Islands
_________________________________________________________________
Number of                5)   Sole Voting    926,736 shares of   
Shares Beneficially           Power          Common Stock, $.01
Owned by Each                                par value ("Common
Reporting Person                             Stock")
                         ________________________________________
                         6)   Shared Voting 
                              Power               -0-
                         ________________________________________
                         7)   Sole Disposi-  926,736 shares of
                              tive Power     Common Stock
                         ________________________________________
                         8)   Shared Dis-
                              positive Power       -0-
                         ________________________________________

9)   Aggregate Amount Beneficially           926,736 shares of 
     Owned by Each Reporting Person          Common Stock
_________________________________________________________________

10)  Check if the Aggregate
     Amount in Row (9)
     Excludes Certain Shares
_________________________________________________________________
11)  Percent of Class
     Represented by                          6.9%
     Amount in Row (9)
_________________________________________________________________
12)  Type of Reporting 
     Person                                  CO
<PAGE>
CUSIP No. 0009283691                                      Page 3 of 7 Pages

                               Schedule 13G
                               ____________

Item 1(a) -    Name of Issuer:  Vista Medical Technologies, Inc.

Item 1(b) -    Address of Issuer's Principal Executive Offices:

               5451 Avenida Encinas, Suite A  
               Carlsbad, CA  92008            
               
Item 2(a) -    Name of Person Filing:

               This statement is being filed on behalf of Biotechnology
               Investments Limited ("BIL" or the "Reporting Person").  BIL
               is a Guernsey, Channel Islands corporation.

Item 2(b) -    Address of Principal Business Office:

               P.O. Box 58
               St. Julian's Court
               St. Peter Port
               Guernsey, Channel Islands  GYI 3BP

Item 2(c) -    Place of Organization:

               Guernsey, Channel Islands

Item 2(d) -    Title of Class of Securities:

               Common Stock, $.01 par value ("Common Stock")

Item 2(e) -    CUSIP Number:  0009283691

Item 3 -       Statements Filed Pursuant to Rules 13d-1(b) or 13d-2(b):

               Not applicable.

Item 4 -       Ownership.

          (a)  Amount Beneficially Owned:

               926,736 shares of Common Stock

          (b)  Percent of Class:

               6.9%
<PAGE>
CUSIP No. 0009283691                                      Page 4 of 7 Pages


          (c)  Number of shares as to which such person has:

               (i)       sole power to vote or to direct the vote:  926,736
                         shares

               (ii)      shared power to vote or to direct the vote:  -0-

               (iii)     sole power to dispose or to direct the disposition
                         of:  926,736 shares

               (iv)      shared power to dispose or to direct the
                         disposition of:  -0-

Item 5 -       Ownership of Five Percent or Less of a Class:

               Not applicable.

Item 6 -       Ownership of More than Five Percent on Behalf of Another
               Person:

               Not applicable.

Item 7 -       Identification and Classification of the Subsidiary Which
               Acquired the Security Being Reported on By the Parent
               Company:

               Not applicable.

Item 8 -       Identification and Classification of Members of the Group:

               Not applicable.

Item 9 -       Notice of Dissolution of Group:

               Not applicable.

Item 10 -      Certification:

               Not applicable.
<PAGE>
CUSIP No. 0009283691                                      Page 5 of 7 Pages


Signature:

          After reasonable inquiry and to the best of my knowledge and
belief, I certify that the information set forth in this statement is true,
complete and correct.

                              BIOTECHNOLOGY INVESTMENTS LIMITED
                              By:  Old Court Limited     
                                                   

                              By /s/ Kathleen K. Schoemaker    
                                _______________________________
                                  Attorney-in-Fact


Date: February 2, 1998
<PAGE>
CUSIP No. 0009283691                                      Page 6 of 7 Pages

                             OLD COURT LIMITED
         P.O. Box 58, St. Julian's Court, St. Peter Port,
                Guernsey, Channel Islands GYI 3BP

Our Ref: PF/domain/POA224  

 28  January 1998 
____

Domain Associates
One Palmer Square
Princeton, New Jersey  08542
USA

Dear Sirs

BIOTECHNOLOGY INVESTMENTS LIMITED

We, Old Court Limited hereby authorise you to execute on behalf of Old
Court Limited a Schedule 13G to be filed with the Securities and Exchange
Commission regarding Biotechnology Investments Limited's holdings of Vista
Medical Technologies, Inc.

Yours very truly
per pro Old Court Limited

/s/ J.J. Nicolle                        /s/ S.E. Shaw      
______________________                  ___________________
J.J. Nicolle, Director                  S.E. Shaw, Director

We confirm that we have authorised Old Court Limited to grant the above
Power of Attorney.

Yours very truly
per pro Biotechnology Investments Limited

/s/ P.A.S. Firth                   
__________________________________
P.A.S. Firth, Authorised Signatory
<PAGE>
CUSIP No. 0009283691                                      Page 7 of 7 Pages


                             OLD COURT LIMITED
         P.O. Box 58, St. Julian's Court, St. Peter Port,
                Guernsey, Channel Islands GYI 3BP

Our Ref: PF/domain/POA79  

 28  January 1998 
____

Domain Associates
One Palmer Square
Princeton, New Jersey  08542
USA

Dear Sirs

BIOTECHNOLOGY INVESTMENTS LIMITED

We, NM Rothschild & Sons (C.I.) Limited hereby authorise you to execute on
behalf of NM Rothschild & Sons (C.I.) Limited a Schedule 13G to be filed
with the Securities and Exchange Commission regarding Biotechnology
Investments Limited's holdings of Vista Medical Technologies, Inc.

Yours very truly
per pro NM Rothschild & Sons (C.I.) Limited

/s/ J.J. Nicolle                        /s/ A.J. Gallienne 
____________________                    ____________________
J.J. Nicolle                            A.J. Gallienne
Authorised Signatory                    Authorised Signatory

We confirm that we have authorised N.M Rothschild & Sons (C.I.) Limited to
grant the above Power of Attorney.

Yours very truly
per pro Biotechnology Investments Limited

/s/ P.A.S. Firth                   
__________________________________
P.A.S. Firth, Authorised Signatory



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