OXIGENE INC
4, 1999-03-10
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
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   FORM 4
__ Check this box if no
   longer subject to
   Section 16. Form 4
   or Form 5 obligations
   may continue. See
   Instruction 1(b).
   (Print or type Responses)
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                UNITED STATES SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549
                  STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

    Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934.
Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(f)
                     of the Investment Company Act of 1940.



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           OMB Approval
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   OMB Number:  3235-0287
   Expires:     September 30, 1998
   Estimated average burden
   hours per response...0.5
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<TABLE>
<CAPTION>
- --------------------------------------------------- ------------------------------------------------------ -------------------------
1.  Name and Address of        2. Issuer Name and Ticker or Trading Symbol  6. Relationship of Reporting Person(s) to Issuer
    Reporting Person*                                                                             (Check all applicable)
                                                                            [X]Director                    __  10% Owner
                                                                            [X] Officer (give title below)  __ Other (specify below)
                                                                            Chief Executive Officer & President
NORDENVALL, Bjorn                       OXiGENE, Inc. (OXGN)                         
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(Last)        (First)   (Middle)               3. IRS or Social        4. Statement for    7. Individual or Joint/Group Reporting
                                                  Security Number of      Month/Year                 (check applicable line)
                                                  Reporting Person                         [X]Form Filed by One Reporting Person
                                                  (Voluntary)             02/99            __ Form Filed by More than One Reporting
c/o OXiGENE, Inc.                                                                             Person
One Copley Place, Suite 602
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                  (Street)                                             5. If Amendment,
                                                                          Date of Original
                                                                          (Month/Year)

Boston, MA  02116                                                         
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(City)         (State)       (Zip)         Table 1 -- Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
<S>                       <C>         <C>              <C>                         <C>                <C>             <C>
- ------------------------------------------ ------------- ----------------- ---------------------------------------------------------
1. Title of Security      2. Trans-   3. Transaction    4. Securities Acquired (A)  5. Amount of      6. Ownership    7. Nature of
   (Instr. 3)                action      Code (Instr.      or Disposed of (D)          Securities        Form:           Indirect
                             Date        8)                (Instr. 3, 4 and 5)         Beneficially      Direct (D)      Beneficial
                             (Month/                                                   Owned at End      or Indirect     Ownership
                             Day/                                                      of Month          (I)             (Instr. 4)
                             Year)                                                     (Instr. 3         (Instr. 4)
                                                                                        and 4
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                                         Code   V          Amount  (A) or (D)  Price
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Common Stock                 02/01/99     P                 70         A        $8.75        70            I                 (1)
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                                                                                        215,500            I                 (2)
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                                                                                         22,000            I                 (3)
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Reminder:  Report on a separate line for each class of securities beneficially owned directly or indirectly.
*  If the form is filed by more than one reporting person, See Instruction 4(b)(v).
</TABLE>

<PAGE>

<TABLE>
FORM 4 (continued)                  Table II -- Derivative Securities Acquired, Disposed of, or Beneficially Owned
                                             (e.g., puts, calls, warrants, options, convertible securities)

<S>       <C>         <C>        <C>       <C>            <C>           <C>           <C>      <C>        <C>         <C> 


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1. Title  2. Conver-  3. Trans-  4. Trans- 5. Number of   6. Date       7. Title      8. Price 9. Number  10. Owner-  11. Nature of
   of        sion or     action     action    Derivative     Exer-         and           of       of          ship        Indirect
   Deri-     Exercise    Date       Code      Securities     cisable       Amount        Deri-    Deri-       Form        Beneficial
   vative    Price of               (Instr.   Acquired (A)   and Expi-     of            vative   vative      of Deri-    Ownership
   Secu-     Deri-       (Month/     8)       or Disposed    ration        Under-        Secu-    Secu-       vative      (Instr. 4)
   rity      vative      Day/                 of (D)         Date          Lying         rity     rities      Security:   
   (Instr.   Security    Year)                (Instr. 3,     (Month/       Securi-       (Instr.  Benefi-     Direct 
   3)                                         4, and 5)      Day/          ties           5)      cially      (D) or 
                                                             Year)         (Instr.                Owned       Indirect
                                                                           3 and 4)                at End      (I)
                                                                                                  of          (Instr.
                                                                                                  Month        4)
                                                                                                  (Instr.
                                                                                                   4)
                                    --------------------------------------------------
                                    Code V    (A)   (D)    Date    Expir- Title Amount
                                                           Exerci- ation        or
                                                           sable   Date         Number
                                                                                of
                                                                                Shares
                                   ---------------------------------------------------
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Explanation of Responses:
(1) Shares are held by daughter.
(2) Shares are held by a corporation organized under the laws of Sweden of which the reporting person is the sole stockholder.
(3) Shares are held through capital insurance placed by the reporting person.


** Intentional misstatements or omissions of       By:  /s/ M. A. Kunst                               March 10, 1999                
   facts constitute Federal Criminal                    ---------------------------------------       ------------------------------
   Violations.                                          M. A. Kunst                                   Date                          
   See 18 U.S.C. and 15 U.S.C. 78ff(a).                 Attorney-in-Fact, pursuant to power                                         
                                                        of attorney filed herewith                                                  
Note:    File three copies of this Form, one       
         of which must be manually signed.
         If space provided is insufficient,
         see Instruction 6 for procedure.

Potential persons who are to respond to the collection of information contained in this form are not required to respond unless form
displays a currently valid OMB number.


</TABLE>



                                POWER OF ATTORNEY

         Know all by these presents, that the undersigned hereby constitutes and
appoints M. Andica Kunst the undersigned's true and lawful attorney-in-fact to:

         (1) execute for and on behalf of the undersigned,  in the undersigned's
         capacity  as  an  officer  and/or   director  of  OXiGENE,   Inc.  (the
         "Company"),  Forms 3, 4, and 5 in accordance  with Section 16(a) of the
         Securities Exchange Act of 1934 and the rules thereunder;

         (2) do  and  perform  any  and  all  acts  for  and  on  behalf  of the
         undersigned which may be necessary or desirable to complete and execute
         any such Form 3, 4, or 5 and  timely  file  such  form with the  United
         States  Securities  and Exchange  Commission  and any stock exchange or
         similar authority; and

         (3) take any other action of any type whatsoever in connection with the
         foregoing  which,  in the opinion of such  attorney-in-fact,  may be of
         benefit  to, in the best  interest  of, or  legally  required  by,  the
         undersigned,  it being  understood that the documents  executed by such
         attorney-in-fact on behalf of the undersigned pursuant to this Power of
         Attorney  shall be in such  form  and  shall  contain  such  terms  and
         conditions   as   such    attorney-in-fact    may   approve   in   such
         attorney-in-fact's discretion.

         The undersigned hereby grants to each such  attorney-in-fact full power
and  authority  to do and  perform  any  and  every  act  and  thing  whatsoever
requisite,  necessary, or proper to be done in the exercise of any of the rights
and  powers  herein  granted,  as  fully  to all  intents  and  purposes  as the
undersigned  might  or  could  do if  personally  present,  with  full  power of
substitution  or  revocation,  hereby  ratifying  and  confirming  all that such
attorney-in-fact,  or such attorney-in-fact's  substitute or substitutes,  shall
lawfully  do or cause to be done by virtue  of this  power of  attorney  and the
rights  and  powers  hereby  granted.  The  undersigned  acknowledges  that  the
foregoing  attorney-in-fact,  in serving in such  capacity at the request of the
undersigned,  are  not  assuming,  nor  is  the  Company  assuming,  any  of the
undersigned's  responsibilities  to comply  with  Section  16 of the  Securities
Exchange Act of 1934.

         This Power of Attorney  shall remain in full force and effect until the
undersigned is no longer  required to file Forms 3, 4, and 5 with respect to the
undersigned's  holdings of and transactions in securities issued by the Company,
unless earlier revoked by the  undersigned in a signed writing  delivered to the
foregoing attorneys-in-fact.

         IN WITNESS  WHEREOF,  the undersigned has caused this Power of Attorney
to be executed as of this 9th day of September, 1998.


                                                /s/ Bjorn Nordenvall
                                             -----------------------------------
                                                Bjorn Nordenvall



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