PALATIN TECHNOLOGIES INC
4, 1997-10-10
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                     U.S. SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                     FORM 4

                  STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

    Filed  pursuant to Section  16(a) of the  Securities  Exchange  Act of 1934,
       Section 17(a) of the Public Utility Holding Company Act of 1935 or
               Section 30(f) of the Investment Company Act of 1940

[  ] Check this box if no longer subject of Section 16. Form 4 or Form 5
     obligations may continue. See Instruction 1(b).

================================================================================
1. Name and Address of Reporting Person*

Aries Domestic Fund, L.P. (1)

c/o Paramount Capital, Inc.
- --------------------------------------------------------------------------------
   (Last)                           (First)             (Middle)

787 Seventh Avenue
- --------------------------------------------------------------------------------
                                    (Street)

New York                             NY                  10019
- --------------------------------------------------------------------------------
   (City)                           (State)              (Zip)


================================================================================
2. Issuer Name and Ticker or Trading Symbol

Palatin Technologies, Inc. (PLTND)

================================================================================
3. IRS or Social Security Number of Reporting Person (Voluntary)


================================================================================
4. Statement for Month/Year

09/97
================================================================================
5. If Amendment, Date of Original (Month/Year)


================================================================================
6. Relationship of Reporting Person(s) to Issuer
   (Check all applicable)

   [   ]   Director                             [ X ]   10% Owner
   [   ]   Officer (give title below)           [   ]   Other (specify below)



================================================================================
7. Individual or Joint/Group Filing (Check applicable line)

   [ X ] Form filed by one Reporting Person   [ ] Form filed by more than one
                                                  Reporting Person


================================================================================
           Table I -- Non-Derivative Securities Acquired, Disposed of,
                             or Beneficially Owned
================================================================================
<TABLE>
<CAPTION>
                                                                                                                6.
                                                                 4.                              5.             Owner-
                                                                 Securities Acquired (A) or      Amount of      ship
                                                    3.           Disposed of (D)                 Securities     Form:     7.
                                                    Transaction  (Instr. 3, 4 and 5)             Beneficially   Direct    Nature of
                                      2.            Code         ------------------------------- Owned at End   (D) or    Indirect
1.                                    Transaction   (Instr. 8)                   (A)             of Month       Indirect  Beneficial
Title of Security                     Date          ------------     Amount      or     Price    (Instr. 3      (I)       Ownership
(Instr. 3)                            (mm/dd/yy)     Code     V                  (D)             and 4)         (Instr.4) (Instr. 4)
- ------------------------------------------------------------------------------------------------------------------------------------
<S>                                   <C>            <C>      <C>    <C>         <C>    <C>      <C>            <C>       <C>


- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

====================================================================================================================================
</TABLE>
* If the Form is  filed  by more  than one  Reporting  Person,  see  Instruction
  4(b)(v).

Reminder: Report on a separate line for each class of securities beneficially
          owned directly or indirectly.


                                  Page 1 of 2



<PAGE>


<PAGE>

FORM 4 (continued)

Table    II --  Derivative  Securities  Acquired,  Disposed of, or  Beneficially
         Owned (e.g., puts, calls, warrants, options, convertible securities)

================================================================================
<TABLE>
<CAPTION>
                                                                                                          9.        10.
                                                                                                          Number    Owner-
                                                                                                          of        ship
                    2.                                                                                    Deriv-    of
                    Conver-                    5.                              7.                         ative     Deriv-   11.
                    sion                       Number of                       Title and Amount           Secur-    ative    Nature
                    or                         Derivative    6.                of Underlying     8.       ities     Secur-   of
                    Exer-             4.       Securities    Date              Securities        Price    Bene-     ity:     In-
                    cise     3.       Trans-   Acquired (A)  Exercisable and   (Instr. 3 and 4)  of       ficially  Direct   direct
                    Price    Trans-   action   or Disposed   Expiration Date   ----------------  Deriv-   Owned     (D) or   Bene-
1.                  of       action   Code     of(D)         (Month/Day/Year)            Amount  ative    at End    In-      ficial
Title of            Deriv-   Date     (Instr.  (Instr. 3,    ----------------            or      Secur-   of        direct   Owner-
Derivative          ative    (Month/  8)       4 and 5)      Date     Expira-            Number  ity      Month     (I)      ship
Security            Secur-   Day/     ------   ------------  Exer-    tion               of      (Instr.  (Instr.   (Instr.  (Instr.
(Instr. 3)          ity      Year)    Code V    (A)   (D)    cisable  Date     Title     Shares  5)       4)        4)       4)
- ------------------------------------------------------------------------------------------------------------------------------------
<S>                 <C>      <C>      <C>  <C>  <C>   <C>    <C>      <C>      <C>       <C>     <C>      <C>       <C>      <C>

Placement Agent     $110     9/30/97  J(2)      350          11/22/97 11/22/02 Series A  350     $.001    350        D
Warrant (right                                                                 Convert-
to buy)                                                                        ible
                                                                               Preferred
                                                                               Stock (3)
- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

====================================================================================================================================
</TABLE>

Explanation of Responses:

(1)  Reporting  person,  Aries  Domestic  Fund,  L.P.:  Paramount  Capital Asset
Management,  Inc.  ("PCAMI") is the general partner of Aries Domestic Fund L.P.,
and is the investment manager for The Aries Trust, a Cayman Islands trust, which
also owns securities of the Issuer. Lindsay A. Rosenwald, M.D., is the President
and sole  shareholder  of PCAMI.  PCAMI and Dr.  Rosenwald  disclaim  beneficial
ownership  of the  securities  held by Aries  Domestic  Fund L.P.  and The Aries
Trust, except to the extent of their pecuniary interest therein.

(2)  Transaction  Code J, "other  acquisition:"  the  securities  acquired  were
assigned to the reporting person by Paramount Capital, Inc., which received them
as placement agent's compensation in connection with an offering of the issuer's
Series A Convertible  Preferred  Stock.  The assigned  securities  represent the
portion of the placement agent's warrants attributable to the reporting person's
investment  in that  offering.  Dr.  Rosenwald  is the Chairman of the Board and
President of Paramount Capital, Inc.

(3)  Each  share  of the  issuer's  Series  A  Convertible  Preferred  Stock  is
convertible into approximately 20.16 shares of the issuer's common stock.



Aries Domestic Fund, L.P.


by:  /s/ Lindsay A. Rosenwald                             October 10, 1997
- ---------------------------------------------           -----------------------
Lindsay A. Rosenwald, M.D., President of Paramount      Date
Capital Asset Management, Inc., general partner of
Aries Domestic Fund, L.P.
      **Signature of Reporting Person


**     Intentional misstatements or omissions of facts constitute Federal
       Criminal Violations.  See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

Note:  File three copies of this Form, one of which must be manually signed.
       If space provided is insufficient, see Instruction 6 for procedure.


       Alternatively,  this Form is permitted to be submitted to the  Commission
       in electronic  format at the option of the reporting  person  pursuant to
       rule 101(b)(4) of Regulation S-T.


                                  Page 2 of 2




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