PALATIN TECHNOLOGIES INC
4, 1997-10-10
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
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                     U.S. SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                     FORM 4

                  STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

    Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934,
       Section 17(a) of the Public Utility Holding Company Act of 1935 or
               Section 30(f) of the Investment Company Act of 1940

[  ] Check this box if no longer subject of Section 16. Form 4 or Form 5
     obligations may continue. See Instruction 1(b).

================================================================================
1. Name and Address of Reporting Person*

The Aries Trust, a Cayman Islands trust (1)

c/o Paramount Capital, Inc.
- --------------------------------------------------------------------------------
   (Last)                           (First)             (Middle)

787 Seventh Avenue
- --------------------------------------------------------------------------------
                                    (Street)

New York                             NY                  10019
- --------------------------------------------------------------------------------
   (City)                           (State)              (Zip)


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2. Issuer Name and Ticker or Trading Symbol

Palatin Technologies, Inc. (PLTND)

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3. IRS or Social Security Number of Reporting Person (Voluntary)


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4. Statement for Month/Year

09/97
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5. If Amendment, Date of Original (Month/Year)


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6. Relationship of Reporting Person(s) to Issuer
   (Check all applicable)

   [   ]   Director                             [ X ]   10% Owner
   [   ]   Officer (give title below)           [   ]   Other (specify below)



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7. Individual or Joint/Group Filing (Check applicable line)

   [ X ] Form filed by one Reporting Person
   [   ] Form filed by more than one Reporting Person


================================================================================
           Table I -- Non-Derivative Securities Acquired, Disposed of,
                             or Beneficially Owned
================================================================================
<TABLE>
<CAPTION>
                                                                                                                6.
                                                                 4.                              5.             Owner-
                                                                 Securities Acquired (A) or      Amount of      ship
                                                    3.           Disposed of (D)                 Securities     Form:     7.
                                                    Transaction  (Instr. 3, 4 and 5)             Beneficially   Direct    Nature of
                                      2.            Code         ------------------------------- Owned at End   (D) or    Indirect
1.                                    Transaction   (Instr. 8)                   (A)             of Month       Indirect  Beneficial
Title of Security                     Date          ------------     Amount      or     Price    (Instr. 3      (I)       Ownership
(Instr. 3)                            (mm/dd/yy)     Code     V                  (D)             and 4)         (Instr.4) (Instr. 4)
- ------------------------------------------------------------------------------------------------------------------------------------
<S>                                   <C>            <C>      <C>    <C>         <C>    <C>      <C>            <C>       <C>


- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

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====================================================================================================================================
</TABLE>
* If the Form is filed by more than one Reporting Person, see Instruction 
  4(b)(v).

Reminder: Report on a separate line for each class of securities beneficially
          owned directly or indirectly.


                                  Page 1 of 2


<PAGE>

FORM 4 (continued)

Table II -- Derivative Securities Acquired, Disposed of, or Beneficially Owned
         (e.g., puts, calls, warrants, options, convertible securities)

================================================================================
<TABLE>
<CAPTION>
                                                                                                          9.        10.    
                                                                                                          Number    Owner- 
                                                                                                          of        ship   
                    2.                                                                                    Deriv-    of     
                    Conver-                    5.                              7.                         ative     Deriv-   11.    
                    sion                       Number of                       Title and Amount           Secur-    ative    Nature 
                    or                         Derivative    6.                of Underlying     8.       ities     Secur-   of     
                    Exer-             4.       Securities    Date              Securities        Price    Bene-     ity:     In-    
                    cise     3.       Trans-   Acquired (A)  Exercisable and   (Instr. 3 and 4)  of       ficially  Direct   direct 
                    Price    Trans-   action   or Disposed   Expiration Date   ----------------  Deriv-   Owned     (D) or   Bene-  
1.                  of       action   Code     of(D)         (Month/Day/Year)            Amount  ative    at End    In-      ficial 
Title of            Deriv-   Date     (Instr.  (Instr. 3,    ----------------            or      Secur-   of        direct   Owner- 
Derivative          ative    (Month/  8)       4 and 5)      Date     Expira-            Number  ity      Month     (I)      ship   
Security            Secur-   Day/     ------   ------------  Exer-    tion               of      (Instr.  (Instr.   (Instr.  (Instr.
(Instr. 3)          ity      Year)    Code V    (A)   (D)    cisable  Date     Title     Shares  5)       4)        4)       4)
- ------------------------------------------------------------------------------------------------------------------------------------
<S>                 <C>      <C>      <C>  <C>  <C>   <C>    <C>      <C>      <C>       <C>     <C>      <C>       <C>      <C>

Placement Agent     $110     9/30/97  J(2)      650          11/22/97 11/22/02 Series A  650     $.001    650        D
Warrant (right                                                                 Convert-   
to buy)                                                                        ible
                                                                               Preferred
                                                                               Stock (3)
- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

- ------------------------------------------------------------------------------------------------------------------------------------

====================================================================================================================================
</TABLE>

Explanation of Responses:

(1) Reporting person, The Aries Trust: Paramount Capital Asset Management,  Inc.
("PCAMI")  is the  investment  manager  for The Aries  Trust and is the  general
partner of Aries Domestic Fund L.P., a Delaware limited partnership,  which also
owns securities of the Issuer. Lindsay A. Rosenwald,  M.D., is the President and
sole shareholder of PCAMI. PCAMI and Dr. Rosenwald disclaim beneficial ownership
of the securities  held by The Aries Trust and Aries Domestic Fund L.P.,  except
to the extent of their pecuniary interest therein.

(2)  Transaction  Code J, "other  acquisition:"  the  securities  acquired  were
assigned to the reporting person by Paramount Capital, Inc., which received them
as placement agent's compensation in connection with an offering of the issuer's
Series A Convertible  Preferred  Stock.  The assigned  securities  represent the
portion of the placement agent's warrants attributable to the reporting person's
investment  in that  offering.  Dr.  Rosenwald  is the Chairman of the Board and
President of Paramount Capital, Inc.

(3)  Each  share  of the  issuer's  Series  A  Convertible  Preferred  Stock  is
convertible into approximately 20.16 shares of the issuer's common stock.



The Aries Trust


by:  /s/ Lindsay A. Rosenwald                                 October 10, 1997
- ---------------------------------------------            -----------------------
Lindsay A. Rosenwald, M.D., President of Paramount               Date
Capital Asset Management, Inc., investment manager
of The Aries Trust
      **Signature of Reporting Person


**     Intentional misstatements or omissions of facts constitute Federal 
       Criminal Violations.  See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

Note:  File three copies of this Form, one of which must be manually signed.
       If space provided is insufficient, see Instruction 6 for procedure.

       Alternatively,   this  Form  is  permitted  to  be  submitted  to  the
       Commission in electronic  format at the option of the reporting person
       pursuant to rule 101(b)(4) of Regulation S-T.


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