<PAGE>
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, DC 20549
SC 13D/A
Under the Securities Exchange Act of 1934
(Amendment No. 3)*
NeXstar Pharmaceuticals, Inc.
(Name of Issuer)
Common Stock, par value $.01 per share
(Title of Class of Securities)
65333B106
(CUSIP Number)
Stephen Distler
E.M. Warburg Pincus & Co., LLC
466 Lexington Avenue
New York, New York 10017
(212) 878-0600
(Name, Address and Telephone Number of Person Authorized to
Receive Notices and Communications)
- with a copy to -
Peter H. Jakes, Esq.
Willkie Farr & Gallagher
787 Seventh Avenue
New York, New York 10019
February 28, 1999
(Date of Event which Requires Filing of this Statement)
If the filing person has previously filed a statement on Schedule 13G to report
the acquisition which is the subject of this Schedule 13D, and is filing this
schedule because of Rule 13d-1(b)(3) or (4), check the following box |_|.
Note: Six copies of this statement, including all exhibits, should be filed with
the Commission. See Rule 13d-l(a) for other parties to whom copies are to be
sent.
*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter
disclosures provided in a prior cover page.
The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).
SEC 1746 (12-91)
<PAGE>
SCHEDULE 13D
- ---------------------
CUSIP: 65333B106
- ---------------------
- ----------- --------------------------------------------------------------------
1 NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Warburg, Pincus Investors, L.P. ID# 13-3549187
- ----------- --------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a)[ ]
(b)[X]
- ----------- --------------------------------------------------------------------
3 SEC USE ONLY
- ----------- --------------------------------------------------------------------
4 SOURCE OF FUNDS*
N/A
- ----------- --------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED PURSUANT TO
ITEMS 2(d) or 2(e) [ ]
- ----------- --------------------------------------------------------------------
6 CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
- --------------------- --------- ------------------------------------------------
7 SOLE VOTING POWER
NUMBER OF
SHARES 0
BENEFICIALLY
--------- ------------------------------------------------
OWNED BY 8 SHARED VOTING POWER
EACH
REPORTING 8,013,547
PERSON
WITH
--------- ------------------------------------------------
9 SOLE DISPOSITIVE POWER
0
--------- ------------------------------------------------
10 SHARED DISPOSITIVE POWER
8, 013,547
- ----------- --------------------------------------------------------------------
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH PERSON
8, 013,547
- ----------- --------------------------------------------------------------------
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN
SHARES* [ ]
- ----------- --------------------------------------------------------------------
13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
28.0%
- ----------- --------------------------------------------------------------------
14 TYPE OF REPORTING PERSON*
PN
- ----------- --------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
INCLUDE BOTH SIDES OF THE COVER PAGE, RESPONSES TO ITEMS 1-7
(INCLUDING EXHIBITS) OF THE SCHEDULE, AND THE SIGNATURE
ATTESTATION.
<PAGE>
SCHEDULE 13D
- ---------------------
CUSIP: 65333B106
- ---------------------
- ----------- --------------------------------------------------------------------
1 NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Warburg, Pincus & Co. ID# 13-6358475
- ----------- --------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a)[ ]
(b)[X]
- ----------- --------------------------------------------------------------------
3 SEC USE ONLY
- ----------- --------------------------------------------------------------------
4 SOURCE OF FUNDS*
N/A
- ----------- --------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED PURSUANT TO
ITEMS 2(d) or 2(e) [ ]
- ----------- --------------------------------------------------------------------
6 CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
- --------------------- --------- ------------------------------------------------
7 SOLE VOTING POWER
NUMBER OF
SHARES 0
BENEFICIALLY
--------- ------------------------------------------------
OWNED BY 8 SHARED VOTING POWER
EACH
REPORTING 8,013,547
PERSON
WITH
--------- ------------------------------------------------
9 SOLE DISPOSITIVE POWER
0
--------- ------------------------------------------------
10 SHARED DISPOSITIVE POWER
8,013,547
- ----------- --------------------------------------------------------------------
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH PERSON
8,013,547
- ----------- --------------------------------------------------------------------
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN
SHARES* [ ]
- ----------- --------------------------------------------------------------------
13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
28.0%
- ----------- --------------------------------------------------------------------
14 TYPE OF REPORTING PERSON*
PN
- ----------- --------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
INCLUDE BOTH SIDES OF THE COVER PAGE, RESPONSES TO ITEMS 1-7
(INCLUDING EXHIBITS) OF THE SCHEDULE, AND THE SIGNATURE
ATTESTATION.
<PAGE>
SCHEDULE 13D
- ---------------------
CUSIP: 65333B106
- ---------------------
- ----------- --------------------------------------------------------------------
1 NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
E.M. Warburg, Pincus & Co., LLC ID# 13-3536050
- ----------- --------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a)[ ]
(b)[X]
- ----------- --------------------------------------------------------------------
3 SEC USE ONLY
- ----------- --------------------------------------------------------------------
4 SOURCE OF FUNDS*
N/A
- ----------- --------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED PURSUANT TO
ITEMS 2(d) or 2(e) [ ]
- ----------- --------------------------------------------------------------------
6 CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
- --------------------- --------- ------------------------------------------------
7 SOLE VOTING POWER
NUMBER OF
SHARES 0
BENEFICIALLY
--------- ------------------------------------------------
OWNED BY 8 SHARED VOTING POWER
EACH
REPORTING 8,013,547
PERSON
WITH
--------- ------------------------------------------------
9 SOLE DISPOSITIVE POWER
0
--------- ------------------------------------------------
10 SHARED DISPOSITIVE POWER
8,013,547
- ----------- --------------------------------------------------------------------
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH PERSON
8,013,547
- ----------- --------------------------------------------------------------------
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN
SHARES* [ ]
- ----------- --------------------------------------------------------------------
13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
28.0%
- ----------- --------------------------------------------------------------------
14 TYPE OF REPORTING PERSON*
OO
- ----------- --------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
INCLUDE BOTH SIDES OF THE COVER PAGE, RESPONSES TO ITEMS 1-7
(INCLUDING EXHIBITS) OF THE SCHEDULE, AND THE SIGNATURE
ATTESTATION.
<PAGE>
SCHEDULE 13D
- ---------------------
CUSIP: 65333B106
- ---------------------
- ----------- --------------------------------------------------------------------
1 NAME OF REPORTING PERSON
S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON
Warburg, Pincus Capital Partners Liquidating Trust ID# 13-7130441
- ----------- --------------------------------------------------------------------
2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a)[ ]
(b)[X]
- ----------- --------------------------------------------------------------------
3 SEC USE ONLY
- ----------- --------------------------------------------------------------------
4 SOURCE OF FUNDS*
N/A
- ----------- --------------------------------------------------------------------
5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDING IS REQUIRED PURSUANT TO
ITEMS 2(d) or 2(e) [ ]
- ----------- --------------------------------------------------------------------
6 CITIZENSHIP OR PLACE OF ORGANIZATION
Delaware
- --------------------- --------- ------------------------------------------------
7 SOLE VOTING POWER
NUMBER OF
SHARES 0
BENEFICIALLY
--------- ------------------------------------------------
OWNED BY 8 SHARED VOTING POWER
EACH
REPORTING 8,013,547
PERSON
WITH
--------- ------------------------------------------------
9 SOLE DISPOSITIVE POWER
0
--------- ------------------------------------------------
10 SHARED DISPOSITIVE POWER
8,013,547
- ----------- --------------------------------------------------------------------
11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH PERSON
8,013,547
- ----------- --------------------------------------------------------------------
12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN
SHARES* [ ]
- ----------- --------------------------------------------------------------------
13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
28.0%
- ----------- --------------------------------------------------------------------
14 TYPE OF REPORTING PERSON*
OO
- ----------- --------------------------------------------------------------------
*SEE INSTRUCTIONS BEFORE FILLING OUT!
INCLUDE BOTH SIDES OF THE COVER PAGE, RESPONSES TO ITEMS 1-7
(INCLUDING EXHIBITS) OF THE SCHEDULE, AND THE SIGNATURE
ATTESTATION.
<PAGE>
Introductory Note.
This Amendment No. 3 amends the Schedule 13D filed by Warburg, Pincus
Investors, L.P., a Delaware limited partnership ("WPI"), Warburg, Pincus Capital
Partners Liquidating Trust (as successor to Warburg, Pincus Capital Partners,
L.P.)("WPCP Liquidating Trust"), Warburg, Pincus & Co., a New York general
partnership ("WP") and E.M. Warburg, Pincus & Co., LLC, a New York limited
liability company (as successor in interest to E.M. Warburg, Pincus & Company)
("EMW LLC"), on March 3, 1995, as amended by Amendments Nos. 1 and 2 thereto
filed on September 15, 1995 and October 31, 1997, respectively (as so amended,
the "Schedule 13D"), relating to the Common Stock, par value $.01 per share
("Company Common Stock"), of NeXstar Pharmaceuticals, Inc. (formerly known as
NeXagen, Inc.), a Delaware corporation (the "Company"). This Amendment No. 3 is
being filed pursuant to Rule 13d-2 of the General Rules and Regulations under
the Securities Exchange Act of 1934, as amended (the "Exchange Act"). Unless
otherwise indicated, all capitalized terms used but not defined herein shall
have the same meaning as set forth in the Schedule 13D.
The Reporting Entities are filing this Amendment to report (i) certain
dispositions of Company Common Stock by WPCP Liquidating Trust subsequent to
October 30, 1997 (as described below in Item 4) and (ii) certain voting
agreements (as described below in Item 6), each dated February 28, 1999, by and
between Gilead Sciences, Inc. ("Gilead") and each of PCP Liquidating Trust and
WPI.
Item 4. Purpose of Transaction
Item 4 of the Schedule 13D is hereby amended by deleting the sixth
paragraph thereof and restating such paragraph as follows:
On September 30, 1997, the partnership agreement of
Warburg, Pincus Capital Partners, L.P. (predecessor to WPCP
Liquidating Trust) ("WPCP") terminated. In connection with such
termination, WPCP "net exercised" a warrant held by it (which
warrant was exercisable for 1,035,294 share of Company Common Stock)
and had the 753,577 shares issued upon such net exercise delivered to
WPCP Liquidating Trust. Concurrently therewith, WPCP distributed to
certain of its limited partners, 1,325,682 shares of Company Common
Stock, and to WPCP Liquidating Trust, all remaining shares of Company
Common Stock then held by it (3,209,106 shares). In addition, in
December 1997 and September 1998 WPCP Liquidating Trust distributed
49,916 and 311,975 shares of Company Common Stock, respectively, to
certain of its beneficiaries. Following the WPCP Liquidating
Distribution and the subsequent distributions described in the
preceding
<PAGE>
sentence, the Reporting Entities continued to be the Company's largest
stockholders.
Item 5. Interest in Securities of the Issuer.
Item 5 of the Schedule 13D is hereby amended by deleting paragraph (a)
thereof and restating paragraph (a) as follows:
(a) As of the date of this Report, (i) WPI has direct
ownership of 4,412,755 shares of Company Common Stock, including
125,000 shares issuable upon exercise of a warrant and (ii) WPCP
Liquidating Trust has direct ownership of 3,600,792 shares of Company
Common Stock (the 4,412,755 shares of Company Common Stock owned
directly by WPI and the 3,600,792 shares of Company Common Stock owned
directly by WPCP Liquidating Trust are collectively referred to as the
"Shares"). By reason of the provisions of Rule 13d-3 under the Act, the
Reporting Entities may together be deemed to own beneficially the
shares of Common Stock owned by WPI and WPCP Liquidating Trust. The
shares of Company Common Stock held by the Reporting Entities represent
approximately 28.0% of the outstanding shares of Company Common Stock.
Item 6. Contracts, Arrangements, Understandings or Relationships with Respect
to Securities of the Issuer.
Item 6 of the Schedule 13D is hereby amended by deleting the final
paragraph thereof and restating such paragraph as follows:
On February 28, 1999, the Company entered into (i) an
Agreement and Plan of Merger (the "Merger Agreement") by and among
Gilead, Gazelle Acquisition Sub, Inc. ("Sub") and the Company, pursuant
to which Sub will be merged into the Company, the Company will survive
as a wholly owned subsidiary of Gilead (the "Merger"), and each issued
and outstanding share of Company Common Stock will be converted into
the right to receive that number of shares of Gilead common stock, par
value $.001 per share ("Gilead Shares") equal to the "Exchange Ratio."
The "Exchange Ratio" equals 0.425, provided, however, that if the
Gilead Share Value (defined as the average of the closing prices of the
Gilead Shares as reported on the Nasdaq National Market for the 20
consecutive trading days ending on the third trading day preceding the
date on which the stockholders of the Company vote on the Merger at the
special meeting of the Company's stockholders called to approve and
adopt the Merger
<PAGE>
Agreement and the Merger) is (i) less than $36.47, then the
Exchange Ratio shall be equal to the lesser of 0.5000 or a fraction
having a numerator equal to $15.50 and having a denominator equal to
the Gilead Share Value, or (ii) greater than $45.88, then the Exchange
Ratio shall be equal to the greater of 0.3786 or a fraction having a
numerator equal to $19.50 and having a denominator equal to the Gilead
Share Value.
In connection with the execution of the Merger Agreement, WPI
and WPCP Liquidating Trust, each in its capacity as a stockholder of
the Company, agreed to vote its respective shares of Company Common
Stock in favor of the approval and adoption of the Merger Agreement and
the Merger. If, however, the Gilead Share Value drops below $27.00, the
obligation to vote such shares in favor of the Merger becomes
terminable.
Item 7. Material to be Filed as Exhibits.
Exhibit 1 Agreement and Plan of Merger dated February 28, 1999 by and among
Gilead Sciences, Inc., Gazelle Acquisition Sub, Inc. and NeXstar
Pharmaceuticals, Inc.
Exhibit 2 Voting Agreement, dated February 28, 1999, by and between Gilead
Sciences, Inc. and Warburg, Pincus Investors, L.P.
Exhibit 3 Voting Agreement, dated February 28, 1999, by and between Gilead
Sciences, Inc. and Warburg, Pincus Capital Partners Liquidating
Trust.
<PAGE>
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.
Dated: March 8, 1999
Warburg, Pincus Investors, L.P.
By: Warburg, Pincus & Co., General Partner
By: /s/ Reuben Leibowitz
---------------------
Partner
Warburg, Pincus & Co.
By: /s/ Reuben Leibowitz
---------------------
Partner
E.M. Warburg, Pincus & Co., LLC
By: /s/ Reuben Leibowitz
--------------------
Member
Warburg, Pincus Capital Partners Liquidating Trust
By: /s/ Reuben Leibowitz
--------------------
Trustee
<PAGE>
================================================================================
AGREEMENT AND PLAN OF MERGER
BY AND AMONG
GILEAD SCIENCES, INC.,
GAZELLE ACQUISITION SUB, INC.
AND
NEXSTAR PHARMACEUTICALS, INC.
DATED AS OF FEBRUARY 28, 1999
================================================================================
<PAGE>
TABLE OF CONTENTS
PAGE
----
ARTICLE I. THE MERGER
SECTION 1.1. The Merger.....................................................2
SECTION 1.2. Effective Time of the Merger...................................2
SECTION 1.3. Effects of the Merger..........................................2
SECTION 1.4. Certificate of Incorporation of the Surviving Corporation......2
SECTION 1.5. By-Laws of the Surviving Corporation...........................2
SECTION 1.6. Directors and Officers of the Surviving Corporation............2
ARTICLE II. CONVERSION OF SHARES
SECTION 2.1. Conversion of Shares...........................................3
(a) Capital Stock of Sub.............................................3
(b) Cancellation of Treasury Stock...................................3
(c) Exchange Ratio for Company Common Stock..........................3
(d) Cancellation of Company Common Stock.............................3
SECTION 2.2. Surrender of Certificates......................................4
SECTION 2.3. Fractional Shares..............................................6
SECTION 2.4. Closing........................................................7
SECTION 2.5. Stock Option Plans.............................................7
SECTION 2.6. Employee Stock Purchase Plan...................................8
ARTICLE III. REPRESENTATIONS AND WARRANTIES
SECTION 3.1. Representations and Warranties of the Company..................8
(a) Due Organization, Good Standing and Power.........................8
(b) Authorization and Validity of Agreement...........................8
(c) Capitalization....................................................9
(d) Consents and Approvals; No Violations............................12
(e) Company Reports and Financial Statements; Accounting Records.....13
(f) Absence of Certain Changes.......................................14
(g) Regulatory Compliance............................................14
(h) Compliance with Laws.............................................17
(i) Litigation.......................................................19
(j) Employee Benefit Plans...........................................19
(k) Employment Agreements............................................22
(l) Taxes............................................................22
(m) Absence of Undisclosed Liabilities...............................24
(n) Patents, Trademarks, Etc.........................................25
(o) Transactions with Directors, Officers and Affiliates.............25
(p) Broker's or Finder's Fee.........................................26
(q) Opinion of Financial Advisor.....................................26
(r) Vote Required....................................................26
(s) Material Contracts...............................................26
(t) Accounting Matters...............................................28
<PAGE>
(u) Tax Treatment....................................................28
(v) Certain Business Practices.......................................28
(w) Governmental Authorizations......................................28
(x) Insurance........................................................29
(y) Y2K Compliance...................................................29
(z) Supply...........................................................30
(aa) Receivables.....................................................30
SECTION 3.2. Representations and Warranties of Parent and Sub..............31
(a) Due Organization, Good Standing and Power........................31
(b) Authorization and Validity of Agreement..........................31
(c) Capitalization...................................................32
(d) Consents and Approvals; No Violations............................33
(e) Parent Reports and Financial Statements; Accounting Records......34
(f) Absence of Certain Changes.......................................35
(g) Compliance with Laws.............................................35
(h) Litigation.......................................................37
(i) Taxes............................................................37
(j) Parent Employee Benefit Plans....................................39
(k) Patents, Trademarks, Etc.........................................40
(l) Broker's or Finder's Fee.........................................41
(m) Accounting Matters...............................................41
(n) Tax Treatment....................................................41
(o) Operations of Sub................................................41
(p) Absence of Undisclosed Liabilities...............................41
(q) Regulatory Compliance............................................42
(r) Certain Business Practices.......................................43
(s) Governmental Authorizations......................................43
(t) Y2K Compliance...................................................44
ARTICLE IV. CONDUCT OF BUSINESS; TRANSACTIONS PRIOR
TO CLOSING DATE; ADDITIONAL AGREEMENTS
SECTION 4.1. Conduct of Business of the Company............................45
SECTION 4.2. Conduct of Business of Parent.................................47
SECTION 4.3. Access to Information Concerning Business and Records.........47
SECTION 4.4. Confidentiality...............................................48
SECTION 4.5. Registration Statement/Joint Proxy Statement; Quotation
on Nasdaq National Market..............................48
SECTION 4.6. Employee Benefits.............................................50
SECTION 4.7. Stockholder Approvals; Recommendations........................50
SECTION 4.8. Stock Options.................................................51
SECTION 4.9. Letters of the Company's Accountants..........................52
SECTION 4.10. Letters of Parent's Accountants..............................52
SECTION 4.11. Notices of Certain Events....................................52
SECTION 4.12. HSR Act......................................................53
SECTION 4.13. Indemnification; Officers' and Directors' Insurance..........53
SECTION 4.14. Efforts......................................................54
SECTION 4.15. Rule 145.....................................................54
SECTION 4.16. No Solicitation..............................................55
-ii-
<PAGE>
SECTION 4.17. Tax Reorganization...........................................57
SECTION 4.18. Convertible Debentures.......................................58
SECTION 4.19. Warrants.....................................................58
ARTICLE V. CONDITIONS PRECEDENT TO MERGER
SECTION 5.1. Conditions Precedent to Obligations of Parent, Sub and
the Company............................................58
(a) Approval of Stockholders.........................................58
(b) HSR Act..........................................................58
(c) No Restraints....................................................58
(d) Statutes.........................................................59
(e) Nasdaq National Market Quotation.................................59
(f) Effectiveness of Registration Statement..........................59
(g) Market Events....................................................59
(h) Accounting Treatment.............................................59
SECTION 5.2. Conditions Precedent to Obligations of Parent and Sub.........59
(a) Accuracy of Representations and Warranties.......................59
(b) Performance by Company...........................................59
(c) Affiliate Agreements.............................................60
(d) Tax Opinion......................................................60
(e) Accountants' Letters.............................................60
(f) Consents.........................................................60
(g) No Governmental Litigation.......................................60
SECTION 5.3. Conditions Precedent to Obligation of the Company.............61
(a) Accuracy of Representations and Warranties.......................61
(b) Performance by Parent and Sub....................................61
(c) Tax Opinion......................................................61
(d) Registration Rights Agreement....................................61
(e) Undertakings.....................................................61
ARTICLE VI. TERMINATION AND ABANDONMENT
SECTION 6.1. Termination...................................................62
SECTION 6.2. Effect of Termination.........................................64
ARTICLE VII. MISCELLANEOUS
SECTION 7.1. Fees and Expenses.............................................64
SECTION 7.2. Representations, Warranties and Agreements....................65
SECTION 7.3. Extension; Waiver.............................................65
SECTION 7.4. Public Announcements..........................................66
SECTION 7.5. Notices.......................................................66
SECTION 7.6. Entire Agreement..............................................67
SECTION 7.7. Binding Effect; Benefit; Assignment...........................67
SECTION 7.8. Amendment and Modification....................................67
SECTION 7.9. Further Actions...............................................68
SECTION 7.10. Headings.....................................................68
SECTION 7.11. Counterparts.................................................68
SECTION 7.12. Applicable Law...............................................68
SECTION 7.13. Severability.................................................68
-iii-
<PAGE>
SECTION 7.14. Enforcement of Agreement.....................................68
SECTION 7.15. "Person" Defined.............................................68
SECTION 7.16. Submission to Jurisdiction...................................68
SECTION 7.17. Subsidiaries.................................................69
EXHIBITS
Exhibit A Form of Affiliate Agreement
Exhibit B Form of Registration Rights Agreement
Exhibit C Form of Undertaking
-iv-
<PAGE>
AGREEMENT AND PLAN OF MERGER
AGREEMENT AND PLAN OF MERGER, dated as of February 28, 1999 (the
"Agreement"), by and among GILEAD SCIENCES, INC., a Delaware corporation
("Parent"), GAZELLE ACQUISITION SUB, INC., a Delaware corporation and a wholly
owned subsidiary of Parent ("Sub"), and NEXSTAR PHARMACEUTICALS, INC., a
Delaware corporation (the "Company").
WHEREAS, the respective Boards of Directors of the Company and
Parent have each determined that it is in the best interests of their respective
companies and stockholders that Parent acquire the business of the Company
pursuant to the terms and conditions set forth in this Agreement;
WHEREAS, the respective Boards of Directors of Parent, Sub and the
Company, and Parent acting as the sole stockholder of Sub, have approved the
merger of Sub into the Company (the "Merger"), pursuant and subject to the terms
and conditions of this Agreement, whereby each issued and outstanding share of
common stock, par value $.01 per share, of the Company ("Company Common Stock")
will be converted into the right to receive shares of common stock, par value
$.001 per share, of Parent ("Parent Shares") in accordance with Section 2.1 of
this Agreement;
WHEREAS, the respective Boards of Directors of the Company and
Parent have each determined that the Merger is fair to, and in the best
interests of, their respective companies and stockholders and have approved the
Merger, and the Board of Directors of the Company has recommended the approval
and adoption of this Agreement by the Company's stockholders;
WHEREAS, in order to induce Parent to enter into this Agreement and
to consummate the Merger, the Company and Parent are entering into a Stock
Option Agreement of even date herewith (the "Share Option Agreement") pursuant
to which the Company is granting to Parent an option to purchase certain shares
of Company Common Stock from the Company under the circumstances specified in
the Share Option Agreement;
WHEREAS, for United States federal income tax purposes, it is
intended that the Merger shall qualify as a reorganization within the meaning of
Section 368(a) of the Internal Revenue Code of 1986, as amended, and the rules
and regulations promulgated thereunder (the "Code"); and
WHEREAS, it is intended that the Merger shall be recorded for
accounting purposes as a pooling of interests under United States generally
accepted accounting principles ("US GAAP");
<PAGE>
NOW, THEREFORE, in consideration of the promises and of the mutual
representations, warranties, covenants and agreements herein contained, the
parties hereto agree as follows:
ARTICLE I.
THE MERGER
SECTION 1.1. THE MERGER. Subject to the terms and conditions of this
Agreement, at the time of the Closing (as defined in Section 2.4 hereof), a
certificate of merger (the "Certificate of Merger") effecting the merger of Sub
with and into the Company, shall be duly executed by the Company in accordance
with the Delaware General Corporation Law (the "DGCL") and shall be filed on the
Closing Date (as defined in Section 2.4 hereof). The Merger shall become
effective upon the filing of the Certificate of Merger with the Secretary of
State of the State of Delaware or at such time thereafter as is provided in the
Certificate of Merger in accordance with the provisions and requirements of the
DGCL. The date and time when the Merger shall become effective is hereinafter
referred to as the "Effective Time."
SECTION 1.2. EFFECTIVE TIME OF MERGER. At the Effective Time, Sub
shall be merged with and into the Company and the separate corporate existence
of Sub shall cease, and the Company shall continue as the surviving corporation
under the laws of the State of Delaware (the "Surviving Corporation").
SECTION 1.3. EFFECTS OF THE MERGER. From and after the Effective
Time, the Merger shall have the effects set forth in Section 259(a) of the DGCL.
SECTION 1.4. CERTIFICATE OF INCORPORATION OF THE SURVIVING
CORPORATION. The Certificate of Incorporation of the Company shall be the
Certificate of Incorporation of the Surviving Corporation after the Effective
Time, and thereafter may be amended in accordance with its terms and as provided
by law and this Agreement.
SECTION 1.5. BY-LAWS OF THE SURVIVING CORPORATION. The By-Laws of
Sub, as in effect immediately prior to the Effective Time, shall be the By-Laws
of the Surviving Corporation.
SECTION 1.6. DIRECTORS AND OFFICERS OF THE SURVIVING CORPORATION.
The directors of Sub immediately prior to the Effective Time shall be the
directors of the Surviving Corporation, and the officers of the Company
immediately prior to the Effective Time shall be the officers of the Surviving
Corporation, in each case until their respective successors are duly elected and
qualified.
-2-
<PAGE>
ARTICLE II.
CONVERSION OF SHARES
SECTION 2.1. CONVERSION OF SHARES. At the Effective Time, by virtue
of the Merger and without any action on the part of the holder of any shares of
Company Common Stock or any holder of capital stock of Sub:
(a) CAPITAL STOCK OF SUB. Each share of capital stock of Sub then
issued and outstanding shall become one fully paid and nonassessable share
of common stock, $0.01 par value per share, of the Surviving Corporation.
(b) CANCELLATION OF TREASURY STOCK. All shares of Company Common
Stock that are owned by the Company as treasury stock shall be canceled
and retired and shall cease to exist and no Parent Shares or other
consideration shall be delivered in exchange therefor.
(c) EXCHANGE RATIO FOR COMPANY COMMON STOCK. Each issued and
outstanding share of Company Common Stock (other than shares to be
canceled in accordance with Section 2.1(b)) shall be converted into the
right to receive that number of Parent Shares equal to the Exchange
Ratio (the Parent Shares issuable upon exchange of shares of Company
Common Stock are referred to as the "Merger Consideration"). For
purposes of this Agreement: (i) "Exchange Ratio" means a fraction equal
to 0.4250, PROVIDED, HOWEVER, that (A) if the Parent Share Value is less
than $36.47, then the Exchange Ratio shall be equal to the lesser of
0.5000 or a fraction having a numerator equal to $15.50 and having a
denominator equal to the Parent Share Value, and (B) if the Parent Share
Value is greater than $45.88, then the Exchange Ratio shall be equal to
the greater of 0.3786 or a fraction having a numerator equal to $19.50
and having a denominator equal to the Parent Share Value; and (ii)
"Parent Share Value" means the average of the closing prices of the
Parent Shares as reported on the Nasdaq National Market for the 20
consecutive trading days ending on the third trading day preceding the
date on which the stockholders of the Company vote on the Merger at the
Special Meeting (as defined in Section 4.7 hereof). If between the date
of this Agreement and the Effective Time the outstanding Parent Shares
or the outstanding Company Common Stock shall be changed into a
different number of shares by reason of any stock dividend, subdivision,
reclassification, split-up, combination or the like, the Exchange Ratio
shall be appropriately adjusted.
(d) RIGHTS OF FORMER HOLDERS OF COMPANY COMMON STOCK. All shares of
Company Common Stock converted into the right to receive Merger
Consideration pursuant to this Section 2.1 shall no longer be outstanding,
and each holder of a
-3-
<PAGE>
certificate representing any such shares shall cease to have any rights
with respect thereto, except the right to receive Merger Consideration to
be issued in consideration therefor upon the surrender of such certificate
in accordance with Section 2.2, without interest.
SECTION 2.2. SURRENDER OF CERTIFICATES. (a) Concurrently with or
prior to the Effective Time, the parties hereto shall designate ChaseMellon
Shareholder Services to act as agent (the "Exchange Agent") for purposes of
exchanging certificates representing shares of Company Common Stock as provided
in Section 2.1. As soon as practicable after the Effective Time, Parent shall
cause the Exchange Agent to mail or make available to each holder of record of a
certificate or certificates which immediately prior to the Effective Time
represented outstanding shares of Company Common Stock whose shares were
converted into the right to receive Merger Consideration pursuant to Section 2.1
a notice and letter of transmittal advising such holder of the effectiveness of
the Merger and the procedure for surrendering to the Exchange Agent such
certificate or certificates which immediately prior to the Effective Time
represented outstanding shares of Company Common Stock in exchange for Merger
Consideration deliverable in respect thereof pursuant to this Article II.
(b) Each holder of shares of Company Common Stock that has been
converted into a right to receive Merger Consideration, upon surrender to the
Exchange Agent of a certificate or certificates representing such Company Common
Stock, together with a properly completed letter of transmittal covering such
shares of Company Common Stock and such other documents as may reasonably be
required by the Exchange Agent or Parent, will be entitled to receive Merger
Consideration in respect of each share of Company Common Stock surrendered.
Until so surrendered, each share of Company Common Stock shall, after the
Effective Time, represent for all purposes, only the right to receive Merger
Consideration. Such letter of transmittal shall be in customary form and contain
such provisions as Parent may reasonably specify (including a provision
confirming that delivery of the certificates which immediately prior to the
Effective Time represented shares of Company Common Stock shall be effected, and
risk of loss and title to such certificates shall pass, only upon delivery of
such certificates to the Exchange Agent).
(c) If any Merger Consideration is to be issued to a Person (as
defined in Section 7.15 hereof) other than the registered holder of the Company
Common Stock represented by the certificate or certificates surrendered with
respect thereto, it shall be a condition to such issuance that the certificate
or certificates so surrendered shall be properly endorsed or otherwise be in
proper form for transfer and that the Person requesting such delivery shall pay
to the Exchange Agent any transfer or other taxes required as a result of such
issuance to
-4-
<PAGE>
a Person other than the registered holder of such Company Common Stock or
establish to the satisfaction of the Exchange Agent that such tax has been paid
or is not payable. If any certificate which immediately prior to the Effective
Time represented shares of Company Common Stock shall have been lost, stolen or
destroyed, Parent may, in its discretion and as a condition precedent to the
issuance of any certificate representing Parent Shares, require the owner of
such lost, stolen or destroyed certificate to provide an appropriate affidavit
and to deliver a bond (in such sum as Parent may reasonably direct) as indemnity
against any claim that may be made against the Exchange Agent, Parent or the
Surviving Corporation with respect to such certificate.
(d) As of the Effective Time, there shall be no further registration
of transfers of shares of Company Common Stock that were outstanding prior to
the Merger. After the Effective Time, certificates representing shares of
Company Common Stock presented to the Surviving Corporation for transfer shall
be canceled and exchanged for the consideration provided for, and in accordance
with the procedures set forth, in this Article II.
(e) At the close of business on the Effective Time, the stock ledger
of the Company with respect to the issuance of Company Common Stock shall be
closed. Six months after the Effective Time, any Merger Consideration made
available to the Exchange Agent and any portion of the Common Stock Trust (as
defined in Section 2.3) that remains unclaimed by the holders of shares of
Company Common Stock shall be returned to Parent upon demand. Any such holder
who has not delivered his certificates which immediately prior to the Effective
Time represented shares of Company Common Stock to the Exchange Agent in
accordance with Section 2.2 prior to that time shall thereafter look only to
Parent and the Surviving Corporation for issuance of Parent Shares in respect of
shares of Company Common Stock. Notwithstanding the foregoing, neither Parent
nor the Surviving Corporation shall be liable to any holder or former holder of
shares of Company Common Stock for any securities delivered or any amount paid
to a public official pursuant to applicable abandoned property laws. Any Parent
Shares remaining unclaimed by holders of shares of Company Common Stock three
years after the Effective Time (or such earlier date immediately prior to such
time as such securities would otherwise escheat to or become property of any
governmental entity or as is otherwise provided by applicable law) shall, to the
extent permitted by applicable law, be free and clear of any claims or interest
of any Person previously entitled thereto.
(f) No dividends, interest or other distributions with respect to
securities of Parent or the Surviving Corporation issuable with respect to
Merger Consideration shall be paid to the holder of any unsurrendered
certificates which formerly
-5-
<PAGE>
represented Company Common Stock until such certificates are surrendered as
provided in this Section. Upon such surrender, there shall be paid, without
interest, to the Person in whose name the Parent Shares representing such
securities are registered, all dividends and other distributions payable in
respect of such securities on a date subsequent to, and in respect of a record
date after, the Effective Time, subject to the effect of applicable abandoned
property laws.
SECTION 2.3. FRACTIONAL SHARES. No fraction of a Parent Share will
be issued, and such fractional interest shall not entitle the owner thereof to
vote or to any rights as a security holder of Parent. In lieu of any such
fractional interest, each holder of certificates which immediately prior to the
Effective Time represented shares of Company Common Stock otherwise entitled to
a fraction of a Parent Share (after aggregating all fractional Parent Shares
issuable to such holder) will be entitled to receive at the time such holder
receives Parent Shares pursuant to Section 2.2(b) hereof and in accordance with
the provisions of this Section 2.3 from the Exchange Agent a cash payment
representing such holder's proportionate interest in the net proceeds
(determined after deducting all commissions, transfer taxes and other
transaction costs) from the sale by the Exchange Agent on behalf of all such
holders of the aggregate of the fractions of Parent Shares which would otherwise
be issued (the "Excess Parent Shares"). The sale of the Excess Parent Shares by
the Exchange Agent shall be executed on the Nasdaq National Market through one
or more market makers in the Parent Shares and shall be executed in round lots
to the extent practicable. Until the net proceeds of such sale or sales have
been distributed to the former holders of shares of the Company Common Stock,
the Exchange Agent will, subject to Section 2.2(e), hold such proceeds in trust
for the former holders of shares of Company Common Stock (the "Common Stock
Trust"). Parent shall pay all commissions, transfer taxes and other
out-of-pocket transaction costs, including the expenses and compensation, of the
Exchange Agent incurred in connection with such sale of the Excess Parent
Shares. The Exchange Agent shall determine the portion of the Common Stock Trust
to which each former holder of shares of Company Common Stock shall be entitled,
if any, by multiplying the amount of the aggregate net proceeds comprising the
Common Stock Trust by a fraction the numerator of which is the amount of the
fractional Parent Share interest to which such former holder of shares of
Company Common Stock is entitled and the denominator of which is the aggregate
amount of fractional Parent Shares to which all former holders of shares of
Company Common Stock are entitled. As soon as practicable after the
determination of the amount of cash, if any, to be paid to former holders of
shares of Company Common Stock in lieu of any fractional Parent Shares, the
Exchange Agent shall make available such amounts to such former holders of
shares of the Company Common Stock without interest.
-6-
<PAGE>
SECTION 2.4. CLOSING. The closing of the Merger (the "Closing")
shall take place at the offices of Willkie Farr & Gallagher, 787 Seventh Avenue,
New York, New York 10019, as soon as practicable after the last of the
conditions set forth in Article V hereof is fulfilled or waived (subject to
applicable law) but in no event later than the fifth business day thereafter, or
at such other time and place and on such other date as Parent and the Company
shall mutually agree (the "Closing Date").
SECTION 2.5. STOCK OPTION PLANS. (a) Prior to the Effective Time,
but subject to the consummation of the Merger, the Board of Directors of the
Company and the committee appointed by the Board to administer the Company's
stock option plans shall use its best efforts to take all action reasonably
necessary or appropriate to provide that each option outstanding under the
Company's 1988 Stock Option Plan, 1993 Incentive Stock Plan, as amended, and
1995 Director Option Plan, as amended (collectively, the "Stock Option Plans"),
shall be converted into and become rights with respect to Parent Shares, and
Parent shall assume each such option in accordance with the terms (as in effect
as of the date of this Agreement) of the Stock Option Plan under which it was
issued and the stock option agreement by which it is evidenced. From and after
the Effective Time, (i) each option assumed by Parent in accordance with this
Section 2.5(a) may be exercised solely for Parent Shares, (ii) the number of
Parent Shares subject to each such option shall be equal to the number of shares
of Company Common Stock subject to such option immediately prior to the
Effective Time multiplied by the Exchange Ratio, rounding down to the nearest
whole share (with cash, less the applicable exercise price, being payable for
any fraction of a share), (iii) the per share exercise price under each such
option shall be adjusted by dividing the per share exercise price under such
option by the Exchange Ratio and rounding up to the nearest cent and (iv) any
restriction on the exercise of any such option shall continue in full force and
effect and the term, exercisability, vesting schedule and other provisions of
such option shall otherwise remain unchanged; PROVIDED, HOWEVER, that each
option assumed by Parent in accordance with this Section 2.5(a) shall, in
accordance with its terms, be subject to further adjustment as appropriate to
reflect any stock dividend, subdivision, reclassification, split-up, combination
or the like subsequent to the Effective Time. Parent shall file with the
Commission, no later than 5 business days after the Effective Time, a
registration statement on Form S-8 relating to Parent Shares issuable with
respect to the options assumed by Parent in accordance with this Section 2.5(a).
(b) The Company shall take all action reasonably necessary (under
the Stock Option Plans and otherwise) to effectuate the provisions of this
Section 2.5 and to ensure that, from and after the Effective Time, holders of
options have no
-7-
<PAGE>
rights with respect thereto other than those specifically provided in this
Section 2.5.
SECTION 2.6. EMPLOYEE STOCK PURCHASE PLAN. Prior to the Effective
Time, but subject to the consummation of the Merger, the Board of Directors of
the Company shall take all action reasonably necessary or appropriate to use the
accumulated payroll deductions in accounts of participants in the Company's
Employee Stock Purchase Plan (the "Stock Purchase Plan") to purchase shares of
Company Common Stock and immediately thereafter terminate the Stock Purchase
Plan.
ARTICLE III.
REPRESENTATIONS AND WARRANTIES
SECTION 3.1. REPRESENTATIONS AND WARRANTIES OF THE COMPANY. The
Company hereby represents and warrants to Parent and Sub as follows:
(a) DUE ORGANIZATION, GOOD STANDING AND POWER. Each of the Company
and its Subsidiaries (as that term is defined in Section 7.17 hereof) is a
corporation duly organized, validly existing and in good standing under
the laws of the jurisdiction of its incorporation and each such
corporation has all requisite power and authority to own, lease and
operate its properties and to carry on its business as now being
conducted. Each of the Company and its Subsidiaries is duly qualified or
licensed to do business and is in good standing in each jurisdiction in
which the property owned, leased or operated by it or the nature of the
business conducted by it makes such qualification necessary, except in
such jurisdictions where the failure to be so qualified or licensed and in
good standing would not have a material adverse effect on the business,
properties, assets, liabilities, condition (financial or otherwise),
operations or results of operations (the "Condition") of the Company and
its Subsidiaries taken as a whole.
(b) AUTHORIZATION AND VALIDITY OF AGREEMENT. The Company has full
corporate power and authority to execute and deliver this Agreement and
the Share Option Agreement, to perform its obligations hereunder and
thereunder and, subject, in the case of this Agreement, to obtaining any
necessary stockholder approval of the Merger, to consummate the
transactions contemplated hereby and thereby. The execution, delivery and
performance of this Agreement and the Share Option Agreement by the
Company, and the consummation by it of the transactions contemplated
hereby and thereby, have been duly authorized by all necessary corporate
action on the part of the Company (including the authorization and
approval of the Board of Directors of the
-8-
<PAGE>
Company), subject (in the case of this Agreement) to the approval of the
Merger by the Company's stockholders in accordance with the DGCL. The
Board of Directors of the Company (at a meeting duly called and held) has
(a) determined that the Merger is advisable and fair and in the best
interests of the Company and its stockholders, and (b) recommended the
approval and adoption of this Agreement and approval of the Merger by the
holders of Company Common Stock and directed that this Agreement and the
Merger be submitted for consideration by the Company's stockholders at the
Special Meeting. The Board of Directors of the Company has taken all
action necessary to render inapplicable, as it relates to Parent, the
provisions of Section 203 of the DGCL. No other corporate action on the
part of the Company is necessary to authorize the execution, delivery and
performance of this Agreement and the Share Option Agreement by the
Company and the consummation of the transactions contemplated hereby and
thereby (other than, in the case of this Agreement, the approval of the
Merger by the holders of at least a majority of the outstanding Company
Common Stock). To the Company's knowledge, no other state takeover statute
or similar statute or regulation applies or purports to apply to the
Merger, this Agreement, the Share Option Agreement or the transactions
contemplated hereby and thereby. This Agreement and the Share Option
Agreement have been duly executed and delivered by the Company and each is
a valid and binding obligation of the Company enforceable against the
Company in accordance with its terms, except to the extent that its
enforceability may be subject to applicable bankruptcy, insolvency,
reorganization, moratorium and similar laws affecting the enforcement of
creditors' rights generally and by general equitable principles.
(c) CAPITALIZATION. (i) The authorized capital stock of the Company
consists of 50,000,000 shares of Company Common Stock, $0.01 par value,
and 5,000,000 shares of preferred stock, $1.00 par value (the "Preferred
Stock"). As of January 31, 1999, (1) 28,670,645 shares of Company Common
Stock were issued and outstanding, (2) 3,169,785 shares of Company Common
Stock were reserved for issuance upon the exercise of outstanding options
granted under the Stock Option Plans, (3) 256,286 shares of Company Common
Stock were reserved for issuance upon exercise of outstanding warrants,
(4) 4,740,740 shares of Company Common Stock were reserved for issuance
upon the conversion of the Company's 6 1/4% Convertible Subordinated
Debentures Due 2004 (the "Convertible Debentures"), (5) no shares of
Preferred Stock were issued and outstanding, and (6) no shares of Company
Common Stock were held in the Company's treasury. All issued and
outstanding shares of Company Common Stock have been duly authorized and
validly issued in compliance with all applicable securities laws and are
fully paid and
-9-
<PAGE>
nonassessable, and none of such shares are subject to, nor were they
issued in violation of, any preemptive rights. None of the outstanding
shares of Company Common Stock is subject to any right of first refusal or
similar right of the Company or any of its Subsidiaries, and, except as
set forth in Schedule 3.1(c)(i) delivered to Parent by the Company prior
to the execution of this Agreement, there is no contract or arrangement
relating to the voting or registration of, or restricting any Person from
purchasing, selling, pledging or otherwise disposing of (or granting any
option or similar right with respect to), any shares of Company Common
Stock. Except as set forth in this Section 3.1(c) or on Schedule 3.1(c)(i)
delivered to Parent by the Company prior to the execution of this
Agreement and except for purchases pursuant to the Company's Stock
Purchase Plan, and except for changes since January 31, 1999 resulting
from the exercise of employee or director stock options or warrants, or
conversion of Convertible Debentures outstanding on such date, (i) there
are no shares of capital stock of the Company authorized, issued or
outstanding and (ii) there are not as of the date hereof, and at the
Effective Time there will not be, any outstanding options, warrants,
rights, subscriptions, claims of any character, agreements, obligations,
convertible or exchangeable securities or other commitments, contingent or
otherwise, relating to Company Common Stock or any other shares of capital
stock of the Company, pursuant to which the Company is or may become
obligated to issue, sell, grant or purchase, redeem or otherwise acquire
shares of Company Common Stock, any other shares of its capital stock or
any securities convertible into, exchangeable for, or evidencing the right
to subscribe for, any shares of the capital stock of the Company. Neither
the Company nor any of its predecessors has ever adopted any stockholder
rights plan (or similar plan commonly referred to as a "poison pill").
(ii) Schedule 3.1(c)(ii) delivered to Parent by the Company
prior to the execution of this Agreement sets forth the following
information with respect to each employee stock option and director stock
option of the Company outstanding as of February 26, 1999: (a) the
particular Stock Option Plan (if any) pursuant to which such option was
granted; (b) the name of the optionee; (c) the number of shares of Company
Common Stock subject to such option; (d) the exercise price of such
option; (e) the date on which such option was granted; (f) the extent to
which such option is vested and exercisable as of February 26, 1999; and
(g) the date on which such option expires. The Company has made available
to Parent accurate and complete copies of all stock option plans pursuant
to which the Company or any of its predecessor entities has ever granted
stock options, and the forms of all stock option agreements evidencing
such options.
-10-
<PAGE>
(iii) Schedule 3.1(c)(iii) delivered to Parent by the Company
prior to the execution of this Agreement sets forth the following
information with respect to each warrant to purchase shares of Company
Common Stock of the Company outstanding as of the date of this Agreement:
(a) the name of the holder of such warrant; (b) the number of shares of
Company Common Stock subject to such warrant; (c) the exercise price of
such warrant; (d) the date on which such warrant was granted; and (e) the
date on which such warrant expires. The Company has made available to
Parent accurate and complete copies of all warrants outstanding as of the
date of this Agreement, and all agreements relating thereto.
(iv) Schedule 3.1(c)(iv) delivered to Parent by the Company
prior to the execution of this Agreement lists all of the Company's
Subsidiaries (except for corporate Subsidiaries with no material assets or
liabilities, contingent or otherwise). Except as set forth on Schedule
3.1(c)(iv), all issued and outstanding shares of capital stock of the
Company's Subsidiaries (other than director's qualifying shares) have been
validly issued, are fully paid and nonassessable, are not subject to, nor
were they issued in violation of, any preemptive rights, and are owned, of
record and beneficially, directly or indirectly, by the Company, free and
clear of all liens, encumbrances, options or claims whatsoever. No shares
of capital stock of any of the Company's Subsidiaries are reserved for
issuance and there are no outstanding or authorized options, warrants,
rights, subscriptions, claims of any character, agreements, obligations,
convertible or exchangeable securities, or other commitments, contingent
or otherwise, relating to the capital stock of any of the Company's
Subsidiaries, pursuant to which such Subsidiary, the Company or any other
affiliate of such Subsidiary is or may become obligated to issue, sell,
grant or purchase or otherwise acquire any shares of capital stock of such
Subsidiary or any securities convertible into, exchangeable for, or
evidencing the right to subscribe for, any shares of capital stock of such
Subsidiary. Except as set forth in Schedule 3.1(c)(iv) or as provided by
applicable law, there are no restrictions of any kind which prevent the
payment of dividends by any of the Company's Subsidiaries. Except (A) for
the Company's Subsidiaries listed on Schedule 3(c)(iv), (B) as otherwise
listed on Schedule 3.1(c)(iv), (C) for ordinary course portfolio
investments in marketable securities and cash equivalents and (D) for
corporate Subsidiaries of the Company with no material assets or
liabilities, contingent or otherwise, the Company does not own, directly
or indirectly, any capital stock or other equity interest in any Person or
have any direct or indirect equity or ownership interest in any Person and
neither the Company nor any of its Subsidiaries is subject to any
obligation or requirement to make any material loan, capital contribution,
-11-
<PAGE>
investment or similar expenditure to or in any Person, except for loans,
capital contributions, investments or similar expenditures by the Company
or any of its Subsidiaries to any existing wholly owned Subsidiary of the
Company or to the Company.
(d) CONSENTS AND APPROVALS; NO VIOLATIONS. Assuming, in the case of
this Agreement, that (i) the filings required under the Hart-Scott-Rodino
Antitrust Improvements Act of 1976, as amended (the "HSR Act"), are made
and the waiting period thereunder has been terminated or has expired; (ii)
the filing with the Securities and Exchange Commission (the "Commission")
of a definitive joint proxy statement (the "Joint Proxy Statement")
relating to the meetings of the Company's stockholders and Parent's
stockholders to be held in connection with the Merger is made; (iii) the
Registration Statement of Parent to be filed with the Commission on Form
S-4 in connection with the issuance of Parent Shares (the "Registration
Statement") is declared effective; (iv) the filing of the Certificate of
Merger and other appropriate merger documents, if any, as required by the
laws of the State of Delaware, is made; and (v) approval of the Merger by
a majority of the outstanding Company Common Stock is obtained, the
execution and delivery of this Agreement and the Share Option Agreement by
the Company and the consummation by the Company of the transactions
contemplated hereby and thereby will not: (1) violate any provision of the
Certificate of Incorporation, as amended, or By-Laws or other charter or
organizational documents of the Company or any of its Subsidiaries, or any
resolution adopted by the stockholders of the Company or the Board of
Directors of the Company or any of its Subsidiaries or any committee
thereof; (2) to the knowledge of the Company, violate any statute,
ordinance, rule, regulation, order or decree of any court or of any
governmental or regulatory body, agency or authority applicable to the
Company or any of its Subsidiaries or by which any of their respective
properties or assets may be bound, including without limitation, any
consent decrees, court orders or judgments; (3) require any filing with,
or permit, consent or approval of, or the giving of any notice to, any
governmental or regulatory body, agency or authority, domestic or foreign
(a "Governmental Entity"), including without limitation, any Governmental
Entity regulating the pharmaceutical business of the Company; or (4)
except as set forth on Schedule 3.1(d)(4) delivered to Parent by the
Company prior to the execution of this Agreement, result in a violation or
breach of, conflict with, constitute (with or without due notice or lapse
of time or both) a default (or give rise to any right of termination,
cancellation, payment or acceleration) under, or result in the creation of
any lien, security interest, charge or encumbrance upon any of the
properties or assets of the Company or any of its Subsidiaries under,
-12-
<PAGE>
any of the terms, conditions or provisions of any note, bond, mortgage,
indenture, license, franchise, permit, agreement, lease or other
instrument or obligation to which the Company or any of its Subsidiaries
is a party, or by which it or any of their respective properties or assets
may be bound or under which the Company or any Subsidiary of the Company
has or may acquire any rights, excluding from the foregoing clauses (2),
(3) and (4) filings, permits, consents, approvals and notices the absence
of which, and violations, breaches, conflicts, defaults and liens which,
in the aggregate, would not have a material adverse effect on the
Condition of the Company and its Subsidiaries taken as a whole.
(e) COMPANY REPORTS AND FINANCIAL STATEMENTS; ACCOUNTING Records.
(i) Since January 1, 1996, the Company has filed all forms, reports and
documents with the Commission required to be filed by it pursuant to the
U.S. federal securities laws and the rules and regulations promulgated
thereunder, and, except for preliminary filings, all such forms, reports
and documents filed with the Commission have complied in all material
respects with all applicable requirements of the U.S. federal securities
laws and the Commission rules and regulations promulgated thereunder. The
Company has heretofore made available to Parent true and complete copies
of all forms, reports, registration statements and other filings filed by
the Company with the Commission since January 1, 1996 (such forms,
reports, registration statements and other filings, together with any
amendments thereto, but excluding any preliminary filings, are sometimes
collectively referred to as the "Company Commission Filings"). As of their
respective dates, the Company Commission Filings did not contain any
untrue statement of a material fact or omit to state a material fact
required to be stated therein or necessary to make the statements therein,
in light of the circumstances under which they were made, not misleading.
(ii) The audited consolidated financial statements and the
unaudited interim financial statements of the Company included in the
Company Commission Filings comply as to form in all material respects with
applicable accounting requirements and with the rules and regulations of
the Commission with respect thereto, were prepared in accordance with US
GAAP (as in effect from time to time) applied on a consistent basis
(except as may be indicated therein or in the notes or schedules thereto)
and fairly present in all material respects the consolidated financial
position of the Company and its consolidated Subsidiaries as of the dates
thereof and the results of their operations and cash flows and changes in
stockholders' equity, as the case may be, for the periods then ended
subject, in the case of the unaudited interim financial statements, to
normal and
-13-
<PAGE>
recurring year-end audit adjustments, any other adjustments described
therein and the fact that certain information and notes have been
condensed or omitted in accordance with the Securities Exchange Act of
1934 (the "Exchange Act"), and the rules promulgated thereunder.
(iii) The unaudited consolidated financial statements of the
Company as of and for the year ended December 31, 1998 delivered to Parent
by the Company prior to the execution of this Agreement comply as to form
in all material respects with applicable accounting requirements, were
prepared in accordance with US GAAP (applied on a basis consistent with
the basis on which the financial statements referred to in Section
3.1(e)(ii) were prepared) and fairly present in all material respects the
consolidated financial position of the Company and its consolidated
Subsidiaries as of December 31, 1998, and the results of their operations
for the year ended December 31, 1998, except that such financial
statements do not include a consolidated statement of cash flows or
stockholders' equity or notes.
(iv) The Company and its Subsidiaries keep proper accounting
records in which all material assets and liabilities, and all material
transactions, of the Company and its Subsidiaries are recorded in
conformity with applicable accounting principles. Except as described on
Schedule 3.1(e)(iv) delivered by the Company to Parent prior to the
execution of this Agreement, no part of the Company's or any Subsidiary's
accounting system or records, or access thereto, is under the control of a
Person who is not an employee of the Company or such Subsidiary.
(f) ABSENCE OF CERTAIN CHANGES. Except as disclosed on Schedule
3.1(f) delivered to Parent by the Company prior to the execution of this
Agreement, since September 30, 1998 (i) there has not been any material
adverse change in the Condition of the Company and its Subsidiaries taken
as a whole; (ii) the businesses of the Company and its Subsidiaries have
been conducted in all material respects only in the ordinary course; (iii)
the Company and its Subsidiaries have not, other than in the ordinary
course of business, increased the compensation of any officer or granted
any general salary or benefits increase to their employees; and (iv)
neither the Company nor any of its Subsidiaries has taken, approved,
authorized or agreed or committed to take any action referred to in
Section 4.1 hereof except as expressly permitted or required thereby.
(g) REGULATORY COMPLIANCE. (i) As to each product subject to the
jurisdiction of the U.S. Food and Drug Administration ("FDA") under the
Federal Food, Drug and Cosmetic Act and the regulations thereunder
("FDCA") (each such product, a "Pharmaceutical Product") that is
-14-
<PAGE>
manufactured, tested, distributed and/or marketed by the Company or any of
its Subsidiaries, such Pharmaceutical Product is being manufactured,
tested, distributed and/or marketed in substantial compliance with all
applicable requirements under FDCA and similar state and foreign laws and
regulations, including but not limited to those relating to
investigational use, premarket clearance, good manufacturing practices,
labeling, advertising, record keeping, filing of reports and security.
(ii) Schedule 3.1(g)(ii) delivered by the Company to Parent
prior to the execution of this Agreement sets forth a list of each
Pharmaceutical Product manufactured, marketed, sold or licensed by the
Company or any Subsidiary as of the date hereof.
(iii) No Pharmaceutical Products have been recalled,
withdrawn, suspended or discontinued by the Company or any of its
Subsidiaries in the United States and outside the United States (whether
voluntarily or otherwise) during the period commencing January 1, 1996 and
ending on the date hereof. No proceedings in the United States and outside
of the United States of which the Company has knowledge (whether completed
or pending) seeking the recall, withdrawal, suspension or seizure of any
Pharmaceutical Product are pending against the Company or any of its
Subsidiaries, nor have any such proceedings been pending at any time
during the period commencing January 1, 1996 and ending on the date
hereof.
(iv) Schedule 3.1(g)(iv) delivered by the Company to Parent
prior to the execution of this Agreement sets forth a list of each of the
Company's and its Subsidiaries' pending and approved New Drug Applications
("NDAs"), Investigational New Drug applications ("INDs") and similar state
or foreign regulatory filings, as of the date hereof. True and complete
copies of such NDAs and INDs, including all supplements, amendments, and
annual reports, have heretofore been made available to Parent. Copies of
correspondence from the FDA, and similar state or foreign regulatory
authorities, and the Company's and its Subsidiaries' responses have
heretofore been made available to Parent. As to each drug for which such
an application has been approved, the Company and its Subsidiaries are in
substantial compliance with 21 U.S.C. ss.ss. 355 or 21 C.F.R. Parts 312,
314 or 430 ET SEQ., respectively, and similar state and foreign laws and
regulations and all terms and conditions of such applications. As to each
such drug, the Company and any relevant Subsidiary, and the officers,
employees or agents of the Company or such Subsidiary have included in the
application for such drug, where required, the certification described in
21 U.S.C. ss. 335a(k)(1) or any similar state or foreign laW or regulation
and the list
-15-
<PAGE>
described in 21 U.S.C. ss. 335a(k)(2) or any similar state or foreign law
or regulation, and such certification and such list was in each case true
and accurate when made and remained true and accurate thereafter. In
addition, the Company and its Subsidiaries are in substantial compliance
with all applicable registration and listing requirements set forth in 21
U.S.C. ss. 360 and 21. C.F.R. Part 207 and all similar state and foreign
laws and regulations.
(v) Each article of drug manufactured and/or distributed by
the Company or any of its Subsidiaries is not adulterated within the
meaning of 21 U.S.C. ss. 351 (or similar state or foreign laws or
regulations) or misbranded within the meaning of 21 U.S.C. ss. 352 (or
similar state or foreign laws or regulations), and is not a product that
is in violation of 21 U.S.C. ss. 355 (or similar state or foreign laws or
regulations).
(vi) Schedule 3.1(g)(vi) delivered by the Company to Parent
prior to the execution of this Agreement sets forth a list of (A) Form
483s, (B) Notices of Adverse Findings and (C) warning letters or other
correspondence from the FDA or state or foreign regulatory authorities in
which the FDA or any such authority asserted that the operations of the
Company or any Subsidiary may not be in compliance with applicable laws,
regulations, orders, judgments or decrees, in each case received by the
Company or such Subsidiary from the FDA or any such authority since
January 1, 1996 to the date hereof and the response of the Company or such
Subsidiary to the FDA or any such authority to such notices from the FDA
or any such authority. True and complete copies of such Form 483s, Notices
of Adverse Findings, letters and other correspondence and the Company's or
Subsidiary's responses have heretofore been made available to Parent.
Except as set forth in Schedule 3.1(g)(vi), all manufacturing operations
of the Company and its Subsidiaries have been and are being conducted in
substantial compliance with the good manufacturing practice regulations
set forth in 21 C.F.R. Parts 210 and 211 and similar state or foreign
regulations.
(vii) Schedule 3.1(g)(vii) delivered by the Company to Parent
prior to the execution of this Agreement sets forth Adverse Reaction
Reports filed by the Company and its Subsidiaries with the FDA or state or
foreign regulatory authorities during the period commencing January 1,
1996 and ending on the date hereof.
(viii) Neither the Company, nor any Subsidiary, nor any
officer, employee or agent of either the Company or any Subsidiary has
made an untrue statement of a material fact or fraudulent statement to the
FDA or any state or foreign regulatory authority, failed to disclose a
material
-16-
<PAGE>
fact required to be disclosed to the FDA or any state or foreign
regulatory authority, or committed an act, made a statement, or failed to
make a statement that, at the time such disclosure was made, could
reasonably be expected to provide a basis for the FDA or any state or
foreign regulatory authority to invoke its policy respecting "Fraud,
Untrue Statements of Material Facts, Bribery, and Illegal Gratuities", set
forth in 56 Fed. Reg. 46191 (September 10, 1991) or any similar policy.
Neither the Company nor any Subsidiary, nor any officer, employee or agent
of either the Company or any Subsidiary, has been convicted of any crime
or engaged in any conduct for which debarment is mandated by 21 U.S.C. ss.
335a(a) or any similar state or foreign law or regulation or authorized by
21 U.S.C. ss. 335a(b) or any similar state or foreign law or regulation.
Schedule 3.1(g)(viii) delivered by the Company to Parent prior to the
execution of this Agreement is an accurate representation of certain
efficacy and safety data from the AmBisome and Abelcet comparative
clinical trial conducted by Fujisawa Healthcare, Inc. (Study No. 034)
(ix) Except as disclosed in the Company Commission Filings
filed with the Commission prior to the date hereof, neither the Company
nor any Subsidiary has received any written notice that the FDA or any
state or foreign regulatory authority has commenced, or threatened to
initiate, any action to withdraw its approval or request the recall of any
product of the Company or any Subsidiary, or commenced, or overtly
threatened to initiate, any action to enjoin production at any facility of
the Company or any Subsidiary.
(x) The Company and its Subsidiaries are, and have at all
times since January 1, 1996 been, in substantial compliance with the
Medicare Anti-kickback Statute, 42 U.S.C. ss. 1320a-7b(b), and
implementing regulations codified at 42 C.F.R. ss. 1001 and with all
similar state or foreign laws and regulations.
(h) COMPLIANCE WITH LAWS. (i) GENERAL. Except with respect to
FDA-related regulatory matters (which are covered by Section 3.1(g)
hereof) and environmental matters (which are covered by Section 3.1(h)(ii)
below), the Company and its Subsidiaries are and at all times since
January 1, 1996 have been in compliance with all applicable laws,
regulations, orders, judgments and decrees, except where the failure to so
comply would not have a material adverse effect on the Condition of the
Company and its Subsidiaries taken as a whole. Since January 1, 1996,
neither the Company nor any of its Subsidiaries has received any written
notice from any Governmental Entity regarding any actual or possible
material violation of, or material failure to comply with, any law,
regulation, order, judgment or decree.
-17-
<PAGE>
(ii) ENVIRONMENTAL MATTERS. Except to the extent that the
inaccuracy of any of the following (or the circumstances giving rise to
such inaccuracy), individually and in the aggregate, would not reasonably
be expected to have a material adverse effect on the Condition of the
Company and its Subsidiaries taken as a whole (after taking into account
any reserves therefor reflected in the consolidated balance sheet of the
Company as of September 30, 1998 contained in its most recently filed
Report on Form 10-Q (the "Company Balance Sheet")) or as set forth on
Schedule 3.1(h)(ii) delivered to Parent by the Company prior to the
execution of this Agreement (none of which scheduled items is expected to
have a material adverse effect on the Condition of the Company and its
Subsidiaries taken as a whole):
(A) the Company, its predecessor entities and its
Subsidiaries are and have been at all relevant times in
compliance with all applicable Environmental Laws and any
permits, authorizations, licenses and certificates issued by
any governmental regulatory authority or entity pursuant to
Environmental Laws;
(B) the Company and its Subsidiaries have
obtained, or made timely application for, all permits required
for their operations under Environmental Laws;
(C) there have been no Releases of any Hazardous
Materials for which the Company or any of its Subsidiaries is
liable or, to the Company's or any of its Subsidiaries'
knowledge, may be held liable, at any location, and there are
no uncontrolled Hazardous Materials present in the environment
or, to the Company's or any of its Subsidiaries' knowledge,
imminent threatened Releases of Hazardous Materials into the
environment at any of the Company's or its Subsidiaries'
facilities; and
(D) neither the Company nor its Subsidiaries have
received any written notice that it is or may be liable for
cleanup or other costs relating to environmental matters as a
result of (1) any Hazardous Materials in the environment at
any facility owned or operated by the Company or its
Subsidiaries or (2) the off-site disposal of Hazardous
Materials generated by the Company or its Subsidiaries at any
of its facilities.
For purposes of this Agreement, the following terms shall have the
following meanings:
-18-
<PAGE>
"Environmental Laws" means all applicable federal, state, local and
foreign statutes, rules, regulations, ordinances, orders, decrees and the
common law relating in any manner to the contamination, pollution or
protection of human health and safety or the environment including without
limitation the Comprehensive Environmental Response, Compensation and
Liability Act ("CERCLA"), the Solid Waste Disposal Act, the Resource
Conservation and Recovery Act, the Clean Air Act, the Clean Water Act, the
Toxic Substance Control Act, the Occupational Safety and Health Act and
similar state laws.
"Hazardous Materials" means all hazardous or toxic substances,
wastes, materials or chemicals, petroleum (including crude oil or any
fraction thereof) and petroleum products, asbestos and asbestos-containing
materials, pollutants, contaminants, which are regulated pursuant to any
applicable Environmental Law and such other materials and substances as
are regulated pursuant to any applicable Environmental Laws.
"Release" shall have the meaning set forth in CERCLA, Section
9601(22).
(i) LITIGATION. Except as disclosed in the Company Commission
Filings filed with the Commission prior to the date hereof or as set forth
on Schedule 3.1(i) delivered to Parent by the Company prior to the
execution of this Agreement, there is no action, suit, proceeding at law
or in equity, or any arbitration or any administrative or other proceeding
by or before (or to the knowledge of the Company any investigation by) any
governmental or other instrumentality or agency, pending, or, to the
knowledge of the Company, threatened, against or affecting the Company or
any of its Subsidiaries, or any of their properties or rights which if
adversely determined would be reasonably likely to have a material adverse
effect on the Condition of the Company and its Subsidiaries taken as a
whole. Except as disclosed in the Company Commission Filings filed with
the Commission prior to the date hereof, neither the Company nor any of
its Subsidiaries is subject to any judgment, order or decree entered in
any lawsuit, proceeding or arbitration which is reasonably likely to have
a material adverse effect on the Condition of the Company and its
Subsidiaries taken as a whole or on the ability of the Company or any
Subsidiary of the Company to conduct its business as presently conducted.
(j) EMPLOYEE BENEFIT PLANS. (i) Schedule 3.1(j) delivered by the
Company to Parent prior to the execution of this Agreement sets forth: (x)
all "employee benefit plans," as defined in Section 3(3) of the Employee
Retirement Income Security Act of 1974, as amended
-19-
<PAGE>
("ERISA"), and all other employee benefit programs and arrangements,
including, without limitation, severance pay, salary continuation for
disability, retirement, deferred or other executive compensation, bonus,
stock purchase, hospitalization, medical insurance, and life insurance,
maintained by the Company or any of its Subsidiaries or to which the
Company or any such Subsidiary is obligated to contribute for current or
former employees of the Company or any such Subsidiary in each case (the
"Employee Benefit Plans "). The Company has made available to Parent true
and complete copies of all Employee Benefit Plans, as in effect, together
with all amendments thereto which will become effective at a later date,
as well as the latest Internal Revenue Service ("IRS") determination
letters obtained with respect to any Employee Benefit Plan intended to be
qualified under Section 401(a) of the Code. True and complete copies of
the (i) most recent annual actuarial valuation report, if any, (ii) last
filed Form 5500 together with all applicable schedules, (iii) summary plan
description (as defined in ERISA), if any, and all modifications thereto
communicated to employees, (iv) most recent annual and periodic accounting
of related plan assets, if any, and (v) such other materials with respect
to the Employee Benefit Plans reasonably requested by Parent in each case,
relating to the Employee Benefit Plans, have been made available to Parent
and are correct in all material respects.
(ii) Except to the extent that any of the following, alone
and in the aggregate, would not reasonably be expected to have a material
adverse effect on the Condition of the Company and its Subsidiaries taken
as a whole: (i) neither the Company nor any of its Subsidiaries nor, to
the Company's knowledge, any of its or its Subsidiaries' directors,
officers, employees or agents has, with respect to any Employee Benefit
Plan, engaged in or been a party to any "prohibited transaction", as such
term is defined in Section 4975 of the Code or Section 406 of ERISA, which
could result in the imposition of either a penalty assessed pursuant to
Section 502(i) of ERISA or a tax imposed by Section 4975 of the Code, in
each case applicable to the Company or any of its Subsidiaries, or any
Employee Benefit Plan; (ii) all Employee Benefit Plans are and have been
at all times in compliance in all respects with the applicable
requirements prescribed by all statutes, orders, or governmental rules or
regulations with respect to such Employee Benefit Plans, including, but
not limited to, ERISA and the Code (except for such requirements that are
not required to be adopted as of the effective date of the applicable
requirement) and, to the knowledge of the Company, there are no pending or
threatened claims, lawsuits or arbitrations (other than routine claims for
benefits), relating to any of the Employee Benefit Plans, which have
-20-
<PAGE>
been asserted or instituted against the Company or any of its
Subsidiaries, any Employee Benefit Plan or the assets of any trust or
group annuity contract for any Employee Benefit Plan; (iii) each Employee
Benefit Plan intended to be qualified under Section 401(a) of the Code has
heretofore been determined by the IRS to be so qualified whether by
determination letter or otherwise; (iv) neither the Company nor any of its
Subsidiaries nor any trade or business which, together with the Company
and its Subsidiaries, is treated as a single employer under Section 414(t)
of the Code (an "ERISA Affiliate") has, or at any time in the last six
years has had, an obligation to contribute to a "defined benefit plan" as
defined in Section 3(35) of ERISA, a pension plan subject to the funding
standards of Section 302 of ERISA or Section 412 of the Code, a
"multiemployer plan" within the meaning of Section 3(37) or 4001(a)(13) of
ERISA or Section 414(f) of the Code or a "multiple employer plan" within
the meaning of Section 210(a) of ERISA or Section 413(c) of the Code; (v)
all (A) insurance premiums required to be paid with respect to, (B)
benefits, expenses, and other amounts due and payable under and (C)
contributions, transfers, or payments required to be made to, any Employee
Benefit Plan prior to the Effective Time will have been paid, made or
accrued on or before the Effective Time;(vi) no Employee Benefit Plan
provides benefits, including, without limitation, death or medical
benefits, beyond termination of service or retirement other than (A)
coverage mandated by law, (B) death or retirement benefits under any
qualified Employee Benefit Plan, (C) deferred compensation benefits
reflected on the books of the Company or (D) arrangements listed on
Schedule 3.1(j); (vii) except as disclosed in Schedule 3.1(j), the
execution and performance of this Agreement will not (A) constitute a
stated triggering event under any Employee Benefit Plan that will result
in any payment (whether of severance pay or otherwise) becoming due from
the Company or any of the Company's Subsidiaries to any officer, employee,
or former employee (or dependents of such employee or former employee), or
(B) accelerate the time of payment to or vesting of, or increase the
amount of, compensation due to any employee, officer or director of the
Company or any Subsidiary of the Company; and (viii) except as disclosed
in Schedule 3.1(j), any amount that could be received (whether in cash or
property or the vesting of property) as a result of any of the
transactions contemplated by this Agreement by any employee, officer or
director of the Company or any Subsidiary of the Company or any of their
affiliates who is a "disqualified individual" (as such term is defined in
proposed Treasury Regulation Section 1.280G-1) under any employment,
severance or termination agreement, other compensation arrangement or
Employee Benefit Plan currently in effect would not be
-21-
<PAGE>
characterized as an "excess parachute payment" (as such term is defined in
Section 280G(b)(1) of the Code).
(k) EMPLOYMENT AGREEMENTS. Except as set forth on Schedule 3.1(k)
delivered to Parent by the Company prior to the execution of this
Agreement, there exists (i) no union, guild or collective bargaining
agreement to which the Company or any Subsidiary is a party, (ii) no
employment, consulting or severance agreement between the Company or any
Subsidiary of the Company and any Person (except for consulting agreements
that individually, and in the aggregate, are not material to the Company),
and (iii) no employment, consulting, severance or indemnification
agreement or other agreement or plan to which the Company or any
Subsidiary is a party that would be altered or result in any bonus, golden
parachute, severance or other payment or obligation to any Person, or
result in any acceleration of the time of payment or in the provision or
vesting of any benefits, as a result of the execution or performance of
this Agreement or as a result of the Merger or the other transactions
contemplated hereby.
(l) TAXES.
(i) Each material Tax Return required to be filed by or on
behalf of the Company and each material Tax Return required to be filed by
or on behalf of the Company's Subsidiaries or any predecessor entities
with any Governmental Entity with respect to any taxable period ending on
or before the Closing Date (the "Company Returns") (i) has been or will be
filed on or before the applicable due date, and (ii) has been, or will be
when filed, prepared in all material respects in compliance with all
applicable laws, regulations, orders, judgments and decrees. All amounts
shown on the Company Returns to be due on or before the Closing Date have
been or will be paid on or before the Closing Date.
(ii) The Company Balance Sheet fully accrues all actual and
contingent liabilities for Taxes with respect to all periods through the
date of the Company Balance Sheet in accordance with US GAAP. The Company
and its Subsidiaries will establish, in the ordinary course of business
and consistent with their past practices, reserves adequate for the
payment of all Taxes that accrue during the period from September 30, 1998
through the Closing Date. Since the date of the Company Balance Sheet,
neither the Company nor any of its Subsidiaries has incurred any material
liability (accrued, unaccrued, matured, unmatured, contingent or
otherwise) for any Tax other than in the ordinary course of its business.
-22-
<PAGE>
(iii) Except as set forth on Schedule 3.1(l)(iii) delivered to
Parent by the Company prior to the execution of this Agreement, no Company
Return has ever been examined or audited by any Governmental Entity. No
extension or waiver of the limitation period applicable to any Company
Returns has been granted (by the Company, any Subsidiary of the Company or
any other Person), and no such extension or waiver has been requested from
the Company or any Subsidiary of the Company.
(iv) No claim or action, suit, proceeding or arbitration is
pending or, to the knowledge of the Company, has been threatened against
or with respect to the Company or any Subsidiary of the Company in respect
of any material Tax. No claim has ever been made by an authority in a
jurisdiction where the Company or any of its Subsidiaries does not file
Tax Returns that it is or may be subject to taxation by that jurisdiction.
There are no unsatisfied liabilities for material Taxes (including
liabilities for interest, additions to tax and penalties thereon and
related expenses) with respect to any notice of deficiency or similar
document received by the Company or any Subsidiary of the Company with
respect to any material Tax (other than liabilities for Taxes asserted
under any such notice of deficiency or similar document which are being
contested in good faith by the Company or any Subsidiary of the Company
and with respect to which adequate reserves for payment have been
established on the Company Balance Sheet). There are no liens or other
security interests for material Taxes upon any of the assets of the
Company or any Subsidiary of the Company except liens for current Taxes
not yet due and payable. Neither the Company nor any Subsidiary of the
Company has entered into or become bound by any agreement or consent
pursuant to Section 341(f) of the Code (or any comparable provision of
state or foreign Tax laws). Neither the Company nor any Subsidiary of the
Company has been, and neither the Company nor any Subsidiary of the
Company will be, required to include any adjustment in taxable income for
any tax period (or portion thereof) pursuant to Section 481 or 263A of the
Code (or any comparable provision under state or foreign Tax laws) as a
result of transactions or events occurring, or accounting methods
employed, prior to the Closing.
(v) There is no contract or arrangement covering any employee
or independent contractor or former employee or independent contractor of
the Company or any Subsidiary of the Company that, considered individually
or considered collectively with any other such contracts and arrangements,
could reasonably be expected to give rise directly or indirectly to the
payment of any amount that would not be deductible pursuant to Section 162
of the Code (or any comparable provision under state or foreign Tax laws).
-23-
<PAGE>
Neither the Company nor any Subsidiary of the Company is, or has ever
been, a party to or bound by any tax indemnity agreement, tax sharing
agreement, tax allocation agreement or similar contract or arrangement.
(vi) For purposes of this Agreement, the following terms shall
have the following meanings:
"Tax" means any tax (including any income tax, franchise
tax, capital gains tax, gross receipts tax, value-added tax, surtax,
estimated tax, unemployment tax, national health insurance tax,
excise tax, AD VALOREM tax, transfer tax, stamp tax, sales tax, use
tax, property tax, business tax, withholding tax or payroll tax),
levy, assessment, tariff, duty (including any customs duty) or
deficiency, and any related charge or amount (including any fine,
penalty or interest), imposed, assessed or collected by or under the
authority of any Governmental Entity.
"Tax Return" means any return (including any information
return), report, statement, declaration, estimate, schedule, notice,
notification, form, election, certificate or other document or
information filed with or submitted to, or required to be filed with
or submitted to, any Governmental Entity in connection with the
determination, assessment, collection or payment of any Tax or in
connection with the administration, implementation or enforcement of
or compliance with any applicable laws, regulations, orders,
judgments and decrees relating to any Tax.
(m) ABSENCE OF UNDISCLOSED LIABILITIES. Except with respect to
environmental matters (which are covered in Section 3.1(h)(ii) hereof) and
FDA-related regulatory matters (which are covered in Section 3.1(g)
hereof), neither the Company nor any of its Subsidiaries has any
indebtedness or liability, absolute or contingent, accrued, unaccrued,
matured or unmatured, direct or indirect, except for: (a) liabilities
identified as such in the "liabilities" column on the Company Balance
Sheet or in the notes thereto; (b) liabilities described on Schedule
3.1(m) delivered to Parent by the Company prior to the execution of this
Agreement; (c) liabilities incurred or accrued in the ordinary course of
business (including liens of current taxes and assessments not in default)
since September 30, 1998; and (d) liabilities that, individually and in
the aggregate, are immaterial in amount. Except as reserved on the Company
Balance Sheet or shown in Schedule 3.1(m), neither the Company nor any of
its Subsidiaries is directly or indirectly liable upon or with respect to
(by discount, repurchase agreements or otherwise), or obligated in any
other way to provide funds in respect of, or to guarantee or
-24-
<PAGE>
assume, any material debt, obligation or dividend of any Person, except
endorsements in the ordinary course of business in connection with the
deposit of items for collection.
(n) PATENTS, TRADEMARKS, ETC. Except as referenced in Schedule
3.1(n) delivered to Parent by the Company prior to the execution of this
Agreement, the Company and its Subsidiaries have obtained or applied for
all material patents, trademarks, trade names, service marks and
copyrights, maintained all material trade secrets and obtained all
licenses and other proprietary intellectual property rights and licenses
as are necessary in connection with the businesses of the Company and its
Subsidiaries. Except as referenced in Schedule 3.1(n), the Company does
not have any knowledge of any conflict with the intellectual property
rights of the Company or any of its Subsidiaries by others which, insofar
as reasonably can be foreseen, could have a material adverse effect on the
Condition of the Company and its Subsidiaries taken as a whole. Except as
referenced in Schedule 3.1(n), the Company does not have any knowledge of
any conflict by the Company or any of its Subsidiaries with the
intellectual property rights of others which, insofar as reasonably can be
foreseen, could have a material adverse effect on the Condition of the
Company and its Subsidiaries taken as a whole.
(o) TRANSACTIONS WITH DIRECTORS, OFFICERS AND AFFILIATES. Except as
disclosed in Schedule 3.1(o) delivered by the Company to Parent prior to
the execution of this Agreement or in the Company Commission Filings filed
with the Commission prior to the date hereof, since January 1, 1996, there
have been no transactions between the Company or any of its Subsidiaries
and any director, officer, employee, stockholder or "Affiliate" (as
defined in Rule 405 under the Securities Act of 1933, as amended (the
"Securities Act")) of the Company or any of its Subsidiaries, including,
without limitation, loans, guarantees or pledges to, by or for the Company
or any of the Company's Subsidiaries from, to, by or for any of such
Persons. Except as disclosed in such Schedule 3.1(o) or in the Company
Commission Filings filed with the Commission prior to the date hereof,
since January 1, 1996, none of the officers or directors of the Company or
any of its Subsidiaries, and no spouse or relative of any of such Persons,
has been a director or officer of, or has had any material direct or
indirect interest in, any Person which during such period has been a
supplier, customer or sales agent of the Company or any of its
Subsidiaries or has competed with or been engaged in any business of the
kind being conducted by the Company or any of its Subsidiaries. Schedule
3.1(o) identifies each Person who is or may be (in
-25-
<PAGE>
the reasonable judgment of the Company) an Affiliate of the Company as of
the date of this Agreement.
(p) BROKER'S OR FINDER'S FEE. Except for Morgan Stanley & Co.
Incorporated (whose fees and expenses as financial advisors to the Company
will be paid by the Company in accordance with the Company's agreement
with such firm, a true and correct copy of which has been previously
delivered to Parent by the Company), no agent, broker, Person or firm
acting on behalf of the Company or any of its Subsidiaries is, or will be,
entitled to any fee, commission or broker's or finder's fees from any of
the parties hereto, or from any Person controlling, controlled by, or
under common control with any of the parties hereto, in connection with
this Agreement or any of the transactions contemplated hereby.
(q) OPINION OF FINANCIAL ADVISOR. The Company has received the
opinion of Morgan Stanley & Co. Incorporated, dated the date hereof, to
the effect that, as of such date, the Merger Consideration is fair from a
financial point of view to the holders of Company Common Stock.
(r) VOTE REQUIRED. The approval of the Merger by the affirmative
vote of a majority of the votes that holders of the outstanding shares of
Company Common Stock are entitled to cast is the only vote of the holders
of any class or series of the Company's capital stock necessary to approve
the transactions contemplated hereby. Holders of Company Common Stock will
not have any appraisal rights or similar rights in connection with the
Merger or any of the other transactions contemplated hereby.
(s) MATERIAL CONTRACTS. Schedule 3.1(s) delivered to Parent by the
Company prior to the execution of this Agreement lists all material
contracts and agreements to which, as of the date hereof, the Company or
any Subsidiary is a party or by which the Company or any Subsidiary is
bound or under which the Company or any Subsidiary has or may acquire any
rights, which were not filed prior to the date hereof as exhibits to the
Company Commission Filings, which involve or relate to (i) obligations of
the Company or any Subsidiary for borrowed money or other indebtedness
where the amount of such obligations exceeds $100,000 individually, (ii)
the lease by the Company or any Subsidiary, as lessee or lessor, of real
property for rent of more than $100,000 per annum, (iii) the purchase or
sale of goods (other than raw material to be purchased by the Company on
terms that are customary and consistent with the past practice of the
Company and in amounts and at prices substantially consistent with past
practices of the Company) or services with an aggregate minimum purchase
price of more than $100,000 per annum, (iv) rights to manufacture and/or
-26-
<PAGE>
distribute any Pharmaceutical Product which accounted for more than
$100,000 of the consolidated revenues of the Company and its Subsidiaries
during the fiscal year ended December 31, 1998 or under which the Company
or any Subsidiary received or paid license or other fees in excess of
$100,000 during any year, (v) the purchase or sale of assets or properties
not in the ordinary course of business having a purchase price in excess
of $100,000, (vi) the right (whether or not currently exercisable) to use,
license (including any "in-license" or "outlicense"), sublicense or
otherwise exploit any intellectual property right or other proprietary
asset of the Company or of any of Subsidiary of the Company or any other
Person which, when considered together with all such other rights, is
material to the Company; (vii) any material collaboration or joint venture
or similar arrangement; (viii) the restriction on the right or ability of
the Company or any Subsidiary of the Company (A) to compete with any other
Person, (B) to acquire any product or other asset or any services from any
other Person, (C) to solicit, hire or retain any Person as an employee,
consultant or independent contractor, (D) to develop, sell, supply,
distribute, offer, support or service any product or any technology or
other asset to or for any other Person, (E) to perform services for any
other Person, or (F) to transact business or deal in any other manner with
any other Person; (ix) any currency hedging; or (x) individual capital
expenditures or commitments in excess of $100,000. All such contracts and
agreements are duly and validly executed by the Company or such
Subsidiary, and are in full force and effect. Neither the Company nor any
of its Subsidiaries has violated or breached, or committed any default
under, any contract or agreement, and, to the knowledge of the Company, no
other Person has violated or breached, or committed any default under, any
contract or agreement, which violation, breach or default (alone or in
combination with other violations, breaches or defaults under such
contract or agreement or under other contracts or agreements) has had or
may reasonably be expected to have a material adverse effect on the
Company and its Subsidiaries taken as a whole. No event has occurred
which, after notice or the passage of time or both, would constitute a
default by the Company or any Subsidiary of the Company under any contract
or agreement or give any Person the right to (A) declare a default or
exercise any remedy under any contract or agreement, (B) receive or
require a rebate, chargeback, penalty or change in delivery schedule under
any contract or agreement, (C) accelerate the maturity or performance of
any contract or agreement, or (D) cancel, terminate or modify any contract
or agreement, in each case which, together with all other events of the
types referred to in clauses (A), (B), (C) and (D) of this sentence has
had or may reasonably be expected to have a material adverse effect on the
Company or any of its Subsidiaries taken as a whole. Except as
-27-
<PAGE>
disclosed on Schedule 3.1(s), all such contracts and agreements will
continue, after the Effective Time, to be binding in accordance with their
respective terms until their respective expiration dates. As soon as
practicable after the date hereof, the Company shall provide Parent with a
list of all leases for real property for rent of more than $30,000 per
annum which are not listed on Schedule 3.1(s).
(t) ACCOUNTING MATTERS. The Company knows of no reasons why the
Merger will not be capable of being treated as a pooling of interest
transaction under APB 16. Neither the Company nor any of its Subsidiaries
nor (to the Company's knowledge) any other Affiliate of the Company has
taken any action that will prevent the Merger from being recorded as a
pooling of interest transaction under APB 16.
(u) TAX TREATMENT. Neither the Company nor any of its Subsidiaries
has taken or agreed to take any action that would prevent the Merger from
qualifying as a reorganization within the meaning of Section 368(a) of the
Code.
(v) CERTAIN BUSINESS PRACTICES. Neither the Company nor any of its
Subsidiaries nor (to the knowledge of the Company) any director, officer,
agent or employee of the Company or any of its Subsidiaries has (i) used
any funds for unlawful contributions, gifts, entertainment or other
unlawful expenses relating to political activity, (ii) made any unlawful
payment to foreign or domestic government officials or employees or to
foreign or domestic political parties or campaigns or violated any
provision of the Foreign Corrupt Practices Act of 1977, as amended, or
(iii) made any other unlawful payment.
(w) GOVERNMENTAL AUTHORIZATIONS. The Company and its Subsidiaries
hold all permits, consents, approvals, variances, licenses, registrations
and other governmental authorizations necessary to enable them to conduct
their respective businesses in the manner in which such businesses are
currently being conducted, except where the failure to hold such permits,
consents, approvals, variances, licenses, registrations and other
governmental authorizations, when considered together with all such other
failures, has not had and would not reasonably be expected to have a
material adverse effect on the Condition of the Company and its
Subsidiaries taken as a whole. All such permits, consents, approvals,
variances, licenses, registrations and other governmental authorizations
are valid and in full force and effect except where the failure to be
valid and in full force and effect, when considered together with all
other such failures, has not had and would not reasonably be expected to
have a material adverse effect on the Company and its Subsidiaries taken
as a whole. The Company and its Subsidiaries are, and at all times since
January 1, 1996
-28-
<PAGE>
have been, in substantial compliance with the terms and requirements of
such permits, consents, approvals, variances, licenses, registrations and
other governmental authorizations, except where the failure, when
considered together with all such other failures, to be in compliance with
the terms and requirements of such permits, consents, approvals,
variances, licenses, registrations and other governmental authorizations
has not had and would not reasonably be expected to have a material
adverse effect on the Condition of the Company and its Subsidiaries taken
as a whole. Neither the execution, delivery or performance of this
Agreement or the Share Option Agreement, nor the consummation of the
Merger or any of the other transactions contemplated by this Agreement and
the Share Option Agreement will (with or without notice or lapse of time)
give any Governmental Entity or other Person the right to revoke,
withdraw, suspend, cancel, terminate or modify: (i) any material grant,
incentive, subsidy, provided to the Company or any of its Subsidiaries; or
(ii) any material permit, consent, approval, variance, license,
registration or other governmental authorization.
(x) INSURANCE. The Company has made available to Parent a summary of
all material insurance policies and all material self insurance programs
and arrangements relating to the business, assets and operations of the
Company and its Subsidiaries. Each of such insurance policies is in full
force and effect. Since January 1, 1996, neither the Company nor any of
its Subsidiaries has received any notice or other communication regarding
any actual or possible (i) cancellation or invalidation of any material
insurance policy, (ii) refusal of any coverage or rejection of any
material claim under any insurance policy, or (iii) material adjustment in
the amount of the premiums payable with respect to any insurance policy.
Except as set forth in Schedule 3.1(x) delivered to Parent by the Company
prior to the execution of this Agreement, there is no pending workers'
compensation or other claim under or based upon any insurance policy of
the Company or any of its Subsidiaries other than claims incurred in the
ordinary cause of business.
(y) Y2K COMPLIANCE. To the knowledge of the Company and its
Subsidiaries, except as set forth in Schedule 3.1(y) delivered to Parent
by the Company prior to the execution of this Agreement, each computer,
computer program and other item of software (whether installed on a
computer or on any other piece of equipment, including firmware) that is
owned, licensed or used by the Company or any of its Subsidiaries for its
internal business operations is Year 2000 Compliant. Except as set forth
in Schedule 3.1(y) delivered to Parent by the Company prior to the
execution of this Agreement, the Company and each of its Subsidiaries has
conducted
-29-
<PAGE>
sufficient Year 2000 compliance testing for each computer, computer
program and item of software referred to in the preceding sentence to be
able to determine whether such computer, computer program or item of
software is Year 2000 Compliant, and to the Company's knowledge, each of
the Company's principal suppliers' products or services provided by such
suppliers to the Company and its Subsidiaries is Year 2000 Compliant
except, in each case where the failure to be Year 2000 Compliant, when
considered together with all such other failures, would not reasonably be
expected to have a material adverse effect on the Company and its
Subsidiaries taken as a whole. A computer, computer program or other item
of software will be deemed "Year 2000 Compliant" only if: (i) the
functions, calculations, and other computing processes of such computer,
program or software (collectively, "Processes") perform in a consistent
and correct manner without interruption regardless of the date on which
the Processes are actually performed and regardless of the date input to
the applicable computer system (whether before, on, or after January 1,
2000); (ii) such computer, program or software accepts, calculates,
compares, sorts, extracts, sequences, and otherwise processes date inputs
and date values, and returns and displays date values, in a consistent and
correct manner regardless of the dates used (whether before, on, or after
January 1, 2000); (iii) such computer, program or software accepts and
responds to year input, if any, in a manner that resolves any ambiguities
as to century in a defined, predetermined and appropriate manner; (iv)
such computer, program or software stores and displays date information in
ways that are unambiguous as to the determination of the century; and (v)
leap years are determined by the following standard: (A) if dividing the
year by 4 yields an integer, it is a leap year, except for years ending in
00, but (B) a year ending in 00 is a leap year if dividing it by 400
yields an integer.
(z) SUPPLY. To the knowledge of the Company, there are no
circumstances or facts concerning third party suppliers of active
ingredients, bulk product and finished product to the Company or any of
its Subsidiaries (as they relate to DaunoXome, AmBisome or MiKasome) that
would have a material adverse effect on the continued and timely supply of
such materials.
(aa) RECEIVABLES. Except as set forth in Schedule 3.1(aa) delivered
to Parent by the Company prior to the execution of this Agreement, all
existing accounts receivable of the Company and its Subsidiaries
(including those accounts receivable reflected on the Company Balance
Sheet that have not yet been collected and those accounts receivable that
have arisen since September 30, 1998 and have not yet been collected)
represent valid obligations of
-30-
<PAGE>
customers of the Company and its Subsidiaries arising from bona fide
transactions entered into in the ordinary course of business. Annexed to
such Schedule 3.1(aa) is an accounts receivable aging report as of
December 31, 1998 which report is true and complete in all material
respects.
SECTION 3.2. REPRESENTATIONS AND WARRANTIES OF PARENT AND SUB.
Parent and Sub represent and warrant to the Company as follows:
(a) DUE ORGANIZATION, GOOD STANDING AND POWER. Each of Parent and
its Subsidiaries (including Sub) is a corporation duly organized, validly
existing and in good standing (where applicable) under the laws of its
jurisdiction of incorporation and each such corporation has all requisite
power and authority to own, lease and operate its properties and to carry
on its business as now being conducted. Each of Parent and its
Subsidiaries is duly qualified or licensed to do business and is in good
standing (where applicable) in each jurisdiction in which the property
owned, leased or operated by it or the nature of the business conducted by
it makes such qualification necessary, except in such jurisdictions where
the failure to be so qualified or licensed and in good standing (where
applicable) would not have a material adverse effect on the Condition of
Parent and its Subsidiaries taken as a whole.
(b) AUTHORIZATION AND VALIDITY OF AGREEMENT. Each of Parent and Sub
has full power and authority to execute and deliver this Agreement, to
perform its obligations hereunder and, subject to obtaining any necessary
stockholder approval of the issuance of Parent Shares in the Merger, to
consummate the transactions contemplated hereby. The execution, delivery
and performance of this Agreement by each of Parent and Sub, and the
consummation by it of the transactions contemplated hereby, have been duly
authorized by all necessary corporate action on the part of Parent and
Sub, subject to the approval of the issuance of Parent Shares in the
Merger by Parent's stockholders in accordance with the rules of the
National Association of Securities Dealers, Inc., and no other corporate
action on the part of either of Parent or Sub is necessary to authorize
the execution, delivery and performance of this Agreement by each of
Parent and Sub and the consummation of the transactions contemplated
hereby (other than the approval of the issuance of Parent Shares in the
Merger in accordance with the rules of the National Association of
Securities Dealers, Inc.). This Agreement has been duly executed and
delivered by each of Parent and Sub and is a valid and binding obligation
of each of Parent and Sub, enforceable against each of Parent and Sub in
accordance with its terms, except to the extent that its enforceability
may be subject to applicable bankruptcy, insolvency, reorganization,
-31-
<PAGE>
moratorium and similar laws affecting the enforcement of creditors' rights
generally and by general equitable principles.
(c) CAPITALIZATION. (i) The authorized capital stock of Parent
consists of 5,000,000 shares of preferred stock (of which 400,000 shares
have been designated Series A Junior Participating Preferred Stock and
1,133,786 shares have been designated Series B Preferred Stock) and
60,000,000 Parent Shares. As of January 31, 1999, (i) there were no shares
of Series A Junior Participating Preferred Stock, 1,133,786 shares of
Series B preferred stock and 30,775,227 Parent Shares issued and
outstanding and (ii) options to subscribe for an aggregate of 4,518,120
Parent Shares were outstanding. All such issued and outstanding Parent
Shares and all Parent Shares issued in connection with the Merger have
been, or will be, as the case may be, duly authorized and validly issued
in compliance with applicable securities laws as fully paid or credited as
fully paid and were not and, in the case of Parent Shares issued in
connection with the Merger, will not have been, issued in violation of any
preemptive right. None of the outstanding shares of Parent Common Stock is
subject to any right of first refusal or similar right of Parent or any of
its Subsidiaries, and, except as set forth in Schedule 3.2(c) delivered to
the Company by Parent prior to the execution of this Agreement, there is
no contract or arrangement relating to the voting or registration of, or
restricting any Person from purchasing, selling, pledging or otherwise
disposing of (or granting any option or similar right with respect to),
any Parent Shares and Parent is under no obligation, nor is it bound by
any contract or arrangement pursuant to which it may become obligated, to
repurchase, redeem or otherwise acquire any outstanding Parent Shares.
Except as set forth in this Section 3.2(c) or on Schedule 3.2(c) delivered
to the Company by Parent and except for changes since January 31, 1999
resulting from the granting or exercise of options or stock purchase
rights under any applicable Parent Employee Benefit Plan (defined below)
or the conversion of shares of convertible preferred stock into Parent
Shares, (i) there is no capital stock of Parent authorized, issued or
outstanding and (ii) there are not as of the date hereof, and at the
Effective Time there will not be, any outstanding options, warrants,
rights, subscriptions, claims of any character, agreements, obligations,
convertible or exchangeable securities, or other commitments, contingent
or otherwise, relating to Parent Shares or any other capital stock of
Parent, pursuant to which Parent is or may become obligated to issue,
sell, grant or purchase, redeem or otherwise acquire Parent Shares or any
other capital stock or securities convertible into, exchangeable for, or
evidencing the right to subscribe for, any capital stock of Parent.
-32-
<PAGE>
(ii) All of the outstanding shares of capital stock of each
of Parent's Subsidiaries (other than directors' qualifying shares), except
for corporate Subsidiaries with no material assets or liabilities,
contingent or otherwise, have been validly issued as fully paid or
credited as fully paid, were not issued in violation of any preemptive
rights and are beneficially owned, directly or indirectly, by Parent, free
and clear of all liens, encumbrances, options or claims whatsoever.
(d) CONSENTS AND APPROVALS; NO VIOLATIONS. Assuming that (i) the
filings required under the HSR Act are made and the waiting period
thereunder has been terminated or has expired; (ii) the filing of the
Joint Proxy Statement is made; (iii) the Registration Statement is
declared effective; (iv) the filing of the Certificate of Merger and other
appropriate merger documents, if any, as required by the laws of the State
of Delaware is made; (v) approval of the issuance of Parent Shares in the
Merger by a majority of the total votes cast at the Parent Stockholders'
Meeting (as defined in Section 4.7(b)) is obtained; and (vi) any
applicable state securities or Blue Sky laws are complied with, the
execution and delivery of this Agreement by Parent and Sub and the
consummation by Parent and Sub of the transactions contemplated hereby
will not: (1) violate any provision of the Certificate of Incorporation or
Bylaws of Parent or the Certificate of Incorporation or By-Laws of Sub, or
any resolution adopted by the stockholders of Parent or the Board of
Directors of Parent or Sub or any committee thereof; (2) to the knowledge
of Parent and Sub, violate any statute, ordinance, rule, regulation, order
or decree of any court or of any governmental or regulatory body, agency
or authority applicable to Parent or any of its Subsidiaries or by which
any of their respective properties or assets may be bound, including,
without limitation, any consent decrees, court orders or judgments; (3)
require any filing with, or permit, consent or approval of, or the giving
of any notice to any Governmental Entity; or (4) except as set forth on
Schedule 3.2(d) delivered to the Company by Parent prior to the execution
of this Agreement, result in a violation or breach of, conflict with,
constitute (with or without due notice or lapse of time or both) a default
(or give rise to any right of termination, cancellation or acceleration)
under, or result in the creation of any lien, security interest, charge or
encumbrance upon any of the properties or assets of Parent or any of its
Subsidiaries under, any of the terms, conditions or provisions of any
note, bond, mortgage, indenture, license, franchise, permit, agreement,
lease or other instrument or obligation to which Parent or any of its
Subsidiaries is a party, or by which it or any of their respective
properties or assets may be bound or under which Parent or any of its
Subsidiaries has or may acquire any rights, excluding from the foregoing
clauses (2), (3)
-33-
<PAGE>
and (4) filings, permits, consents, approvals and notices, the absence of
which, and violations, breaches, defaults, conflicts and liens which, in
the aggregate, would not have a material adverse effect on the Condition
of Parent and its Subsidiaries taken as a whole.
(e) PARENT REPORTS AND FINANCIAL STATEMENTS; ACCOUNTING Records. (i)
Since January 1, 1996, Parent has filed all forms, reports and documents
with the Commission required to be filed by it pursuant to the U.S.
federal securities laws and the rules and regulations promulgated
thereunder, and, except for preliminary filings, all such forms, reports
and documents filed with the Commission have complied in all material
respects with all applicable requirements of the U.S. federal securities
laws and the Commission rules and regulations promulgated thereunder.
Parent has heretofore made available to the Company true and complete
copies of all forms, reports, registration statements and other filings
filed by the Company with the Commission since January 1, 1996 (such
forms, reports, registration statements and other filings, together with
any amendments thereto, but excluding any preliminary filings, are
sometimes collectively referred to as the "Parent Commission Filings"). As
of their respective dates, the Parent Commission Filings did not contain
any untrue statement of a material fact or omit to state a material fact
required to be stated therein or necessary to make the statements therein,
in light of the circumstances under which they were made, not misleading.
(ii) The audited consolidated financial statements included
in the Parent Commission Filings comply as to form in all material
respects with applicable accounting requirements and with the rules and
regulations of the Commission with respect thereto, were prepared in
accordance with US GAAP (as in effect from time to time), applied on a
consistent basis (except as may be indicated therein or in the notes or
schedules thereto) and fairly present in all material respects the
consolidated financial position of Parent and
-34-
<PAGE>
its consolidated Subsidiaries as of the dates thereof and the results of
their operations and cash flows and changes in stockholders' equity, as
the case may be, for the periods then ended. The unaudited interim
financial statements included in the Parent Commission Filings comply as
to form in all material respects with applicable accounting regulations
and with the rules and regulations of the Commission with respect thereto,
were prepared in accordance with US GAAP (as in effect from time to time)
applied on a basis consistent with the basis on which the audited
financial statements referred to in the preceding sentence were prepared
(except as may be indicated therein or in the notes or schedules thereto)
and fairly present the consolidated financial position of Parent and its
consolidated Subsidiaries as of the dates thereof and the results of their
operations and cash flows and changes in stockholders' equity, as the case
may be, for the periods then ended subject to normal and recurring
year-end audit adjustments and any other adjustments described therein and
the fact that certain information and notes have been condensed or omitted
in accordance with the Exchange Act and the rules promulgated thereunder.
(iii) The audited consolidated financial statements of Parent
as of and for the year ended December 31, 1998 delivered to the Company by
Parent prior to the execution of this Agreement comply as to form in all
material respects with applicable accounting requirements, were prepared
in accordance with US GAAP applied on a basis consistent with the basis on
which the financial statements referred to in Section 3.2(e)(ii) were
prepared and fairly present in all material respects the consolidated
financial position of Parent and its consolidated Subsidiaries as of
December 31, 1998, and the results of their operations and cash flows and
changes in stockholders' equity for the year ended December 31, 1998.
(iv) Parent and its Subsidiaries keep proper accounting
records in which all material assets and liabilities, and all material
transactions, of Parent and its Subsidiaries are recorded in conformity
with applicable accounting principles. No part of Parent's or any
Subsidiary's accounting system or records, or access thereto, is under the
control of a Person who is not an employee of Parent or such Subsidiary.
(f) ABSENCE OF CERTAIN CHANGES. Except as disclosed on Schedule
3.2(f) delivered to the Company by Parent, since December 31, 1998: (i)
there has not been any material adverse change in the Condition of Parent
and its Subsidiaries taken as a whole; (ii) the businesses of Parent and
its Subsidiaries have been conducted in all material respects only in the
ordinary course; and (iii) Parent and its Subsidiaries have not, other
than in the ordinary course of business, increased the compensation of any
officer or granted any general salary or benefits increase to their
employees.
(g) COMPLIANCE WITH LAWS. (i) GENERAL. Except with respect to
FDA-related regulatory matters (which are covered by Section 3.2(q)
hereof) and environmental matters (which are covered by Section 3.2(g)(ii)
below), Parent and its Subsidiaries are, and at all times since January 1,
1996 have been, in compliance with all applicable laws, regulations,
orders, judgments and decrees, except where the failure to so comply would
not have a material adverse effect on the Condition of Parent and its
Subsidiaries taken
-35-
<PAGE>
as a whole. Since January 1, 1996, neither Parent nor any of its
Subsidiaries has received any notice or other communication from any
Governmental Entity or other Person regarding any actual or possible
material violation of, or material failure to comply with, any law,
regulation, order, judgment or decree.
(ii) ENVIRONMENTAL MATTERS. Except to the extent that the
inaccuracy of any of the following (or the circumstances giving rise to
such inaccuracy), individually or in the aggregate, would not reasonably
be expected to have a material adverse effect on the Condition of Parent
and its Subsidiaries taken as a whole (after taking into account any
reserves therefor reflected in the audited consolidated balance sheet of
Parent as of December 31, 1998) or as set forth on Schedule 3.2(g)(ii)
delivered to the Company by Parent prior to the execution of this
Agreement (none of which scheduled items are expected to have a material
adverse effect on the Condition of the Parent and its Subsidiaries taken
as a whole):
(A) Parent and its Subsidiaries are and have been
at all relevant times in compliance with all applicable
Environmental Laws and any permits, authorizations, licenses
and certificates issued by any governmental regulatory
authority or entity pursuant to Environmental Laws;
(B) Parent and its Subsidiaries have obtained, or
made timely application for, all permits required for their
operations under Environmental Laws;
(C) there have been no Releases of any Hazardous
Materials for which the Parent or any of its Subsidiaries is
liable or, to Parent's or any of its Subsidiaries' knowledge,
may be held liable, at any location, and there are no
uncontrolled Hazardous Materials present in the environment
or, to Parent's or any of its Subsidiaries' knowledge,
imminent threatened Releases of Hazardous Materials into the
environment at any of Parent's or its Subsidiaries'
facilities; and
(D) neither Parent nor its Subsidiaries have
received any written notice that it is or may be liable for
cleanup or other costs relating to environmental matters as a
result of (1) any Hazardous Materials in the environment at
any facility owned or operated by Parent or its Subsidiaries
or (2) the off-site disposal of
-36-
<PAGE>
Hazardous Materials generated by Parent or its Subsidiaries at
any of its facilities.
(h) LITIGATION. Except as disclosed in Parent Commission Filings
filed with the Commission prior to the date hereof or as set forth on
Schedule 3.2(h) delivered to the Company by Parent, there is no action,
suit or proceeding at law or in equity, or any arbitration or any
administrative or other proceeding by or before (or to the knowledge of
Parent any investigation by) any governmental or other instrumentality or
agency, pending, or, to the knowledge of Parent, threatened, against or
affecting Parent or any of its Subsidiaries, or any of their properties or
rights which if adversely determined would be reasonably likely to have a
material adverse effect on the Condition of Parent and its Subsidiaries
taken as a whole. Except as disclosed in Parent Commission Filings filed
with the Commission prior to the date hereof, neither Parent nor any of
its Subsidiaries is subject to any judgment, order or decree entered in
any lawsuit, proceeding or arbitration which is reasonably likely to have
a material adverse effect on the Condition of Parent and its Subsidiaries
taken as a whole or on the ability of Parent or any Subsidiary of Parent
to conduct its business as presently conducted.
(i) TAXES. Each material Tax Return required to be filed by or
on behalf of Parent and each material Tax Return required to be filed by
or on behalf of Parent's Subsidiaries with any Governmental Entity with
respect to any taxable period ending on or before the Closing Date (the
"Parent Returns") (a) has been or will be filed on or before the
applicable due date, and (b) has been, or will be when filed, prepared in
all material respects in compliance with all applicable laws, regulations,
orders, judgments and decrees. All amounts shown on the Parent Returns to
be due on or before the Closing Date have been or will be paid on or
before the Closing Date.
(ii) Parent's audited consolidated balance sheet as of
December 31, 1998 (the "Parent Balance Sheet") fully accrues all actual
and contingent liabilities for Taxes with respect to all periods through
December 31, 1998 in accordance with US GAAP. Parent and its Subsidiaries
will establish, in the ordinary course of business and consistent with
their past practices, reserves adequate for the payment of all Taxes that
accrue during the period from December 31, 1998 through the Closing Date.
Since December 31, 1998, neither Parent nor any of its Subsidiaries has
incurred any material liability (accrued, unaccrued, matured, unmatured,
contingent or otherwise) for any Tax other than in the ordinary course of
its business.
-37-
<PAGE>
(iii) No material Parent Return has ever been examined or
audited by any Governmental Entity. No extension or waiver of the
limitation period applicable to any material Parent Returns has been
granted (by Parent, any Subsidiary of Parent or any other Person), and no
such extension or waiver has been requested from Parent or any Subsidiary
of Parent.
(iv) No claim or action, suit, proceeding or arbitration is
pending or, to the knowledge of Parent, has been threatened against or
with respect to Parent or any Subsidiary of Parent in respect of any
material Tax. No claim has ever been made by an authority in a
jurisdiction where Parent or any of its Subsidiaries does not file Tax
Returns that it is or may be subject to taxation by that jurisdiction.
There are no unsatisfied liabilities for material Taxes (including
liabilities for interest, additions to tax and penalties thereon and
related expenses) with respect to any notice of deficiency or similar
document received by Parent or any Subsidiary of Parent with respect to
any material Tax (other than liabilities for Taxes asserted under any such
notice of deficiency or similar document which are being contested in good
faith by Parent or any Subsidiary of Parent and with respect to which
adequate reserves for payment have been established on the Parent Balance
Sheet). There are no liens or other security interests for material Taxes
upon any of the assets of Parent or any Subsidiary of Parent except liens
for current Taxes not yet due and payable. Neither Parent nor any
Subsidiary of Parent has entered into or become bound by any agreement or
consent pursuant to Section 341(f) of the Code (or any comparable
provision of state or foreign Tax laws). Neither Parent nor any Subsidiary
of Parent has been, and neither Parent nor any Subsidiary of Parent will
be, required to include any adjustment in taxable income for any tax
period (or portion thereof) pursuant to Section 481 or 263A of the Code
(or any comparable provision under state or foreign Tax laws) as a result
of transactions or events occurring, or accounting methods employed, prior
to the Closing.
(v) There is no contract or arrangement covering any employee
or independent contractor or former employee or independent contractor of
Parent or any Subsidiary of Parent that, considered individually or
considered collectively with any other such contracts and arrangements,
could reasonably be expected to give rise directly or indirectly to the
payment of any amount that would not be deductible pursuant to Section 162
of the Code (or any comparable provision under state or foreign Tax laws).
Neither Parent nor any Subsidiary of Parent is, or has ever been, a party
to or bound by any tax indemnity agreement, tax sharing
-38-
<PAGE>
agreement, tax allocation agreement or similar contract or arrangement.
(j) PARENT EMPLOYEE BENEFIT PLANS. Except to the extent that any of
the following, either alone or in the aggregate, would not reasonably be
expected to have a material adverse effect on the Condition of Parent and
its Subsidiaries taken as a whole: (i) neither Parent nor its Subsidiaries
nor, to Parent's knowledge, any of its or its Subsidiaries' directors,
officers, employees or agents, with respect to any employee benefit plan,
as defined in Section 3(3) of ERISA, and all other employee benefit
programs and arrangements, including, without limitation, severance pay,
salary continuation for disability, retirement, deferred or other
executive compensation, bonus, stock purchase, hospitalization, medical
insurance, and life insurance, maintained by Parent or its Subsidiaries or
to which Parent or any such Subsidiary is obligated to contribute
thereunder for current or former employees of Parent or its Subsidiaries
(the "Parent Employee Benefit Plans") has engaged in or been a party to
any "prohibited transaction", as such term is defined in Section 4975 of
the Code or Section 406 of ERISA, which could result in the imposition of
either a penalty assessed pursuant to Section 502(i) of ERISA or a tax
imposed by Section 4975 of the Code, in each case applicable to Parent or
any of its Subsidiaries or any Parent Employee Benefit Plan; (ii) except
as disclosed on Schedule 3.2(j) delivered to the Company by Parent prior
to the execution of this Agreement, all Parent Employee Benefit Plans are
and have been at all times in compliance in all respects with the
applicable requirements prescribed by all statutes, orders, or
governmental rules or regulations with respect to such Parent Employee
Benefit Plans, including, but not limited to, ERISA and the Code (except
for such requirements that are not required to be adopted as of the
effective date of the applicable requirement) and, to the knowledge of
Parent, there are no pending or threatened claims, lawsuits or
arbitrations (other than routine claims for benefits), relating to any of
the Parent Employee Benefit Plans, which have been asserted or instituted
against Parent or any of its Subsidiaries, any Parent Employee Benefit
Plan or the assets of any trust or group annuity contract for any Parent
Employee Benefit Plan; (iii) each Parent Employee Benefit Plan intended to
be qualified under Section 401(a) of the Code has heretofore been
determined by the IRS to be so qualified whether by determination letter
or otherwise; (iv) neither Parent nor any of its Subsidiaries or any trade
or business which, together with Parent and its Subsidiaries, is treated
as a single employer under Section 414(t) of the Code (a "Parent ERISA
Affiliate") has, or at any time within the last six years has had, an
obligation to contribute to a "defined benefit plan" as defined in Section
3(35) of ERISA, a
-39-
<PAGE>
pension plan subject to the funding standards of Section 302 of ERISA or
Section 412 of the Code, a "multiemployer plan" within the meaning of
Section 3(37) or 4001(a)(13) of ERISA or Section 414(f) of the Code or a
"multiple employer plan" within the meaning of Section 210(a) of ERISA or
Section 413(c) of the Code; (v) all (A) insurance premiums required to be
paid with respect to, (B) benefits, expenses, and other amounts due and
payable under and (C) contributions, transfers, or payments required to be
made to, any Parent Employee Benefit Plan prior to the Effective Time will
have been paid, made or accrued on or before the Effective Time;(vi) no
Parent Employee Benefit Plan provides benefits, including, without
limitation, death or medical benefits, beyond termination of service or
retirement other than (A) coverage mandated by law, (B) death or
retirement benefits under any qualified Parent Employee Benefit Plan, or
(C) deferred compensation benefits reflected on the books of Parent or (D)
arrangements listed on Schedule 3.2(j); (vii) except as disclosed in
Schedule 3.2(j), the execution and performance of this Agreement will not
(A) constitute a stated triggering event under any Parent Employee Benefit
Plan that will result in any payment (whether of severance pay or
otherwise) becoming due from Parent or any of Parent's Subsidiaries to any
officer, employee, or former employee (or dependents of such employee), or
(B) accelerate the time of payment or vesting, or increase the amount of
compensation due to any employee, officer or director of Parent or any
Subsidiary of Parent; and (viii) except as disclosed in Schedule 3.2(j),
any amount that could be received (whether in cash or property or the
vesting of property) as a result of any of the transactions contemplated
by this Agreement by any employee, officer or director of Parent or any
Subsidiary of Parent or any of its affiliates who is a "disqualified
individual" (as such term is defined in proposed Treasury Regulation
Section 1.280G-1) under any employment, severance or termination
agreement, other compensation arrangement or Parent Employee Benefit Plan
currently in effect would not be characterized as an "excess parachute
payment" (as such term is defined in Section 280G(b)(1) of the Code).
(k) PATENTS, TRADEMARKS, ETC. Except as referenced in Schedule
3.2(k) provided by Parent to the Company prior to the execution of this
Agreement, Parent and its Subsidiaries have obtained or applied for all
material patents, trademarks, trade names, service marks and copyrights,
maintained all material trade secrets and obtained all material licenses
and other proprietary intellectual property rights and licenses and other
proprietary intellectual property rights as are necessary in connection
with the businesses of Parent and its Subsidiaries. Except as referenced
in Schedule 3.2(k), Parent does not have any knowledge of any conflict
with the intellectual property
-40-
<PAGE>
rights of Parent or any of its Subsidiaries by others or any knowledge of
any conflict by Parent or any of its Subsidiaries with the intellectual
property rights of others which, insofar as reasonably can be foreseen,
could have a material adverse effect on the Condition of Parent and its
Subsidiaries taken as a whole.
(l) BROKER'S OR FINDER'S FEE. Except for J.P. Morgan
Securities, Inc. (whose fees and expenses as financial advisor to
Parent will be paid by Parent in accordance with Parent's agreement
with such firm), no agent, broker, Person or firm acting on behalf of
Parent or Sub is, or will be, entitled to any fee, commission or
broker's or finder's fees from any of the parties hereto, or from any
Person controlling, controlled by, or under common control with any of
the parties hereto, in connection with this Agreement or any of the
transactions contemplated hereby.
(m) ACCOUNTING MATTERS. Parent knows of no reason why the Merger
will not be capable of being treated as a pooling of interest transaction
under APB 16. Neither Parent nor any of its Subsidiaries nor to its
knowledge any other Affiliate of Parent has taken any action that will
prevent the Merger from being recorded as a pooling of interest
transaction under APB 16.
(n) TAX TREATMENT. Neither Parent nor any of its Subsidiaries has
taken or agreed to take any action that would prevent the Merger from
qualifying as a reorganization within the meaning of Section 368(a) of the
Code.
(o) OPERATIONS OF SUB. Sub was formed solely for the purpose of
engaging in the transactions contemplated hereby, has engaged in no other
material business activities and has conducted its operations only as
contemplated hereby.
(p) ABSENCE OF UNDISCLOSED LIABILITIES. Except with respect to
environmental matters (which are covered in Section 3.2 (g)(ii) hereof)
and FDA-related regulatory matters (which are covered in Section 3.2(q)
hereof), Parent does not have any indebtedness or liability except for (a)
liabilities identified as such in the "liabilities" column on the Parent
Balance Sheet or in the notes thereto; (b) liabilities described in Parent
Commission Filings filed with the Commission prior to the date hereof or
on Schedule 3.2(p) delivered to the Company by Parent prior to the
execution of this Agreement; (c) liabilities incurred or accrued in the
ordinary course of business (including liens of current taxes and
assessments not in the default) since December 31, 1998; and (d)
liabilities that, individually and in the aggregate, are immaterial in
amount. Except as reserved on the Parent Balance Sheet or shown in
Schedule 3.2(p), neither Parent nor Sub is directly or indirectly
-41-
<PAGE>
liable upon or with respect to (by discount, repurchase agreements or
otherwise), or obligated in any other way to provide funds in respect of,
or to guarantee or assume, any material debt, obligation or dividend of
any Person, except endorsements in the ordinary course of business in
connection with the deposit of items for collection.
(q) REGULATORY COMPLIANCE. (i) As to each Pharmaceutical Product
that is manufactured, tested, distributed and/or marketed by Parent or any
of its Subsidiaries, such product is being manufactured, tested,
distributed and/or marketed in substantial compliance with all applicable
requirements under FDCA and similar state and foreign laws and
regulations, including but not limited to those relating to
investigational use, premarket clearance, good manufacturing practices,
labeling, advertising, record keeping, filing of reports and security.
(ii) As to each drug manufactured, marketed, sold or
licensed by Parent in the United States for which an NDA and similar state
or foreign regulatory filings, has been approved or an IND has been
submitted to the FDA and become effective, Parent and its Subsidiaries are
in substantial compliance with 21 U.S.C. ss.ss. 355 or 357 or 21 C.F.R.
Parts 312, 314 or 430 ET SEQ., 512, or 514 ET SEQ., respectively, and
similar state and foreign laws and regulations and all terms and
conditions of such applications. As to each such drug, Parent and any
relevant Subsidiary, and the officers, employees or agents of Parent or
such Subsidiary have included in the application for such drug, where
required, the certification described in 21 U.S.C. ss. 335a(k)(1) or any
similar state or foreign law or regulation and the list described in 21
U.S.C. ss. 335a(k)(2) or any similar state or foreign law or regulation,
and such certification and such list was in each case true and accurate
when made and remained true and accurate thereafter. In addition, Parent
and its Subsidiaries are in substantial compliance with all applicable
registration and listing requirements set forth in 21 U.S.C. ss. 360 and
21 C.F.R. Part 207 and all similar state and foreign laws and regulations.
(iii) Each article of drug manufactured and/or distributed by
Parent or any of its Subsidiaries is not adulterated within the meaning of
21 U.S.C. ss. 351 (or similar state or foreign laws or regulations) or
misbranded within the meaning of 21 U.S.C. ss. 352 (or similar state or
foreign laws or regulations), and is not a product that is in violation of
21 U.S.C. ss. 355 (or similar state or foreign laws or regulations).
(iv) Except as set forth in Schedule 3.2(q)(iv) delivered to
the Company by Parent prior to the execution of this Agreement, all
manufacturing operations of Parent and
-42-
<PAGE>
its Subsidiaries in the United States have been and are being conducted in
substantial compliance with the good manufacturing practice regulations
set forth in 21 C.F.R. Parts 210 and 211 and similar state or foreign
regulations.
(v) Except as disclosed in the Parent Commission Filings filed
with the Commission prior to the date hereof, neither Parent nor any of
its Subsidiaries has received any written notice that the FDA or any other
state or foreign regulatory authority has commenced, or threatened to
initiate, any action to withdraw its approval or request the recall of any
product of Parent or any of its Subsidiaries, or commenced, or overtly
threatened to initiate, any action to enjoin production at any facility of
Parent or any of its Subsidiaries.
(vi) Neither Parent, nor any of its Subsidiaries, nor any
officer, employee or agent of either Parent or any of its Subsidiaries has
made an untrue statement of a material fact or fraudulent statement to the
FDA or any state or foreign regulatory authority, failed to disclose a
material fact required to be disclosed to the FDA or any state or foreign
regulatory authority, or committed an act, made a statement, or failed to
make a statement that, at the time such disclosure was made, could
reasonably be expected to provide a basis for the FDA or any state or
foreign regulatory authority to invoke its policy respecting "Fraud,
Untrue Statements of Material Facts, Bribery, and Illegal Gratuities", set
forth in 56 Fed. Reg. 46191 (September 10, 1991) or any similar policy.
Neither Parent nor any of its Subsidiaries, nor any officer, employee or
agent of either Parent or any of its Subsidiaries, has been convicted of
any crime or engaged in any conduct for which debarment is mandated by 21
U.S.C. ss. 335a(a) or any similar state or foreign law or regulation or
authorized by 21 U.S.C. ss. 335a(b) or any similar state or foreign law or
regulation.
(r) CERTAIN BUSINESS PRACTICES. Neither Parent nor any of its
Subsidiaries nor (to the knowledge of Parent) any director, officer, agent
or employee of Parent or any of its Subsidiaries has (i) used any funds
for unlawful contributions, gifts, entertainment or other unlawful
expenses relating to political activity, (ii) made any unlawful payment to
foreign or domestic government officials or employees or to foreign or
domestic political parties or campaigns or violated any provision of the
Foreign Corrupt Practices Act of 1977, as amended, or (iii) made any other
unlawful payment.
(s) GOVERNMENTAL AUTHORIZATIONS. Parent and its Subsidiaries hold
all permits, consents, approvals, variances, licenses, registrations and
other governmental authorizations necessary to enable them to conduct
their
-43-
<PAGE>
respective businesses in the manner in which such businesses are currently
being conducted, except where the failure to hold such permits, consents,
approvals, variances, licenses, registrations and other governmental
authorizations has not had and would not reasonably be expected to have a
material adverse effect on the Condition of Parent and its Subsidiaries
taken as a whole. All such permits, consents, approvals, variances,
licenses, registrations and other governmental authorizations are valid
and in full force and effect except where the failure to be valid and in
full force and effect, when considered together will all other such
failures, has not had and would not reasonably be expected to have a
material adverse effect on the Condition of Parent and its Subsidiary
taken as a whole. Parent and its Subsidiaries are, and at all times since
January 1, 1996 have been, in substantial compliance with the terms and
requirements of such permits, consents, approvals, variances, licenses,
registrations and other governmental authorizations, except where the
failure to be in compliance with the terms and requirements of such
permits, consents, approvals, variances, licenses, registrations and other
governmental authorizations has not had and would not reasonably be
expected to have a material adverse effect on the Condition of Parent and
its Subsidiaries taken as a whole. Neither the execution, delivery or
performance of this Agreement nor the consummation of the Merger or any of
the other transactions contemplated by this Agreement will (with or
without notice or lapse of time) give any Governmental Entity or other
Person the right to revoke, withdraw, suspend, cancel, terminate or
modify: (i) any material grant, incentive, subsidy provided to Parent or
any of its Subsidiaries or (ii) any material permit, consent, approval,
variance, license, registration or other governmental authorization.
(t) Y2K COMPLIANCE. To the knowledge of Parent and its Subsidiaries,
except as set forth in Schedule 3.2(t) delivered to the Company by Parent
prior to the execution of this Agreement, each computer, computer program
and other item of software (whether installed on a computer or on any
other piece of equipment, including firmware) that is owned, licensed or
used by Parent or any of its Subsidiaries for its internal business
operations is Year 2000 Compliant. Except as set forth in Schedule 3.2(t)
delivered to the Company by Parent prior to the execution of this
Agreement, Parent and each of its Subsidiaries has conducted sufficient
Year 2000 compliance testing for each computer, computer program and item
of software referred to in the preceding sentence to be able to determine
whether such computer, computer program or item of software is Year 2000
Compliant, and to Parent's knowledge each of Parent's principal supplier's
products or services provided by such suppliers to Parent and its
Subsidiaries is Year 2000 Compliant
-44-
<PAGE>
except, in each case where the failure to be Year 2000 Compliant would not
reasonably be expected to have a material adverse effect on the Condition
of Parent and its Subsidiaries taken as a whole.
ARTICLE IV.
CONDUCT OF BUSINESS; TRANSACTIONS PRIOR
TO CLOSING DATE; ADDITIONAL AGREEMENTS
SECTION 4.1. CONDUCT OF BUSINESS OF THE COMPANY. The Company agrees
that, except as expressly permitted, required or contemplated by this Agreement
or otherwise consented to or approved in writing by Parent, during the period
commencing on the date hereof and ending on the Closing Date:
(a) The Company and each of its Subsidiaries will conduct their
respective operations in all material respects only according to their
ordinary and usual course of business and will use their reasonable
efforts to preserve intact their respective business organizations, keep
available the services of their directors, officers and employees,
preserve in full force and effect all material licenses and approvals held
by them and maintain satisfactory relationships with suppliers,
distributors, clients and others having material business relationships
with them;
(b) Neither the Company nor any of its Subsidiaries will (i) make
any change in or amendment to its Certificate of Incorporation or By-Laws
or other charter or organizational documents; (ii) issue or sell any
shares of its capital stock or share capital (other than in connection
with the exercise of options granted under the Stock Option Plans and
warrants or convertible securities outstanding on the date hereof or
pursuant to the Stock Purchase Plan) or any other securities, or issue,
sell or grant any securities exchangeable for or convertible into, or
options (other than employee stock options to purchase no more than a
total of 250,000 shares of Company Common Stock, which may be granted to
employees in the ordinary course of business), warrants or rights to
purchase or subscribe to, or enter into any arrangement or contract with
respect to the issuance, grant or sale of, any shares of its capital stock
or any of its other securities, or make any other changes in its capital
structure; (iii) declare, pay or make any dividend or other distribution
or payment with respect to, or split, combine, redeem or reclassify, any
shares of its capital stock or other securities; (iv) make or authorize
any capital expenditures in excess of those set forth in Schedule 4.1(b)
delivered to Parent by the Company prior to the execution of
-45-
<PAGE>
this Agreement or in excess of $200,000, individually, or $1,000,000, in
the aggregate; (v) enter into or amend in any material respect any other
material contracts or commitments except for contracts and amendments made
in the ordinary course of business, consistent with past practice and
containing only normal and customary terms; (vi) acquire, lease or license
any rights or other assets (other than as contemplated by clause (iv)
above), other than in the ordinary course of business and consistent with
past practice, or acquire, lease or license any rights or other assets
having a value in an amount in excess of $200,000, individually, or
$1,000,000, in the aggregate, or dispose of (including by way of sale,
lease, license or encumbrance), other than in the ordinary course of
business and consistent with past practice, a material amount of assets or
release, relinquish or assign any material rights under any material
contract; (vii) except as contemplated by this Agreement (including
Section 2.5 hereof) or as may be required by law, establish, adopt, enter
into, accelerate the vesting under or amend any employee or non-employee
benefit plan or program, employment agreement, option, license agreement
or retirement agreement, or pay any bonus or contingent compensation
(except any bonuses or other payments required under any existing
compensation programs or benefit plans or arrangements and severance
payments under any existing severance plans in each case listed on
Schedule 3.1(j)), or increase the amount of the wages, salary,
commissions, fringe benefits or other compensation or remuneration payable
to any of its directors, officers or employees (except that the Company
may provide routine, reasonable salary increases to its non-officer
employees in connection with the Company's customary employee review
process); (viii) hire any employee with an annual base salary in excess of
$100,000; (ix) change any of its sales policies, revenue recognition
policies, product return policies, personnel policies or other business
policies outside the ordinary course of business; (x) take or permit to be
taken any action that would adversely affect its ability to consummate the
Merger or the other transactions contemplated hereby or could preclude
Parent from accounting for the Merger as a "pooling of interests"; (xi)
take or permit to be taken any action that could reasonably be expected to
prevent the Merger from constituting a reorganization within the meaning
of Section 368(a) of the Code; (xii) make any material Tax election;
(xiii) form or acquire any Subsidiary; (xiv) enter into any hedging,
option or derivative or other similar transaction or any foreign exchange
position or contract for the exchange of currency outside the ordinary
course of business or inconsistent with past practices; (xv) suspend,
terminate or otherwise discontinue or materially modify (except as
required by a Governmental Entity) any planned or ongoing clinical trials
or similar activities relating to DaunoXome, AmBisome,
-46-
<PAGE>
MiKasome, NX211 or NX1838; (xvi) lend money to any Person or incur any
indebtedness for borrowed money (other than by drawing under current
revolving credit agreements (as such agreements are in effect on the date
hereof and without giving effect to any waivers of any of the provisions
of such agreements)) or guarantee any indebtedness or issue or sell any
debt securities or warrants or rights to acquire any debt securities of
the Company or any of its Subsidiaries or guarantee any debt securities of
others; (xvii) agree, in writing or otherwise, to take any of the
foregoing actions; (xviii) make any material change in its method of
accounting or record keeping not otherwise required by US GAAP; or (xix)
commence or agree to the settlement of any material litigation;
(c) The Company will not, nor will the Company permit any of its
Subsidiaries to, purchase or acquire, or offer to purchase or acquire, any
shares of its capital stock; and
(d) The Company will deliver to Parent all of the Company's monthly
and quarterly, if any, financial statements for periods and dates
subsequent to December 31, 1998, as soon as practicable after the same are
available to the Company.
SECTION 4.2. CONDUCT OF BUSINESS OF PARENT. Parent agrees that,
except as set forth on Schedule 4.2, and except as expressly permitted, required
or contemplated by this Agreement, or otherwise consented to or approved in
writing by the Company, during the period commencing on the date hereof and
ending on the Closing Date, Parent and each of its Subsidiaries will conduct
their respective operations in all material respects only according to their
ordinary and usual course of business and will use their reasonable efforts to
preserve intact their respective business organizations, keep available the
services of their directors, officers and employees, preserve in full force and
effect all material licenses and approvals held by them and maintain
satisfactory relationships with suppliers, distributors, clients and others
having material business relationships with them.
SECTION 4.3. ACCESS TO INFORMATION CONCERNING BUSINESS AND RECORDS.
(a) During the period commencing on the date hereof and ending on the Closing
Date, the Company shall, upon reasonable notice, afford to Parent and Parent's
counsel, accountants and other authorized representatives, reasonable access
during normal business hours to the properties, personnel, advisors, books and
records of the Company and its Subsidiaries in order that they may have the
opportunity to make such investigations as they shall desire of the affairs of
the Company and its Subsidiaries; such investigation shall not, however, affect
the representations and warranties made in this Agreement. The Company agrees to
cause its officers and employees to furnish
-47-
<PAGE>
such additional financial and operating data and other information and respond
to such inquiries as Parent shall from time to time request.
(b) During the period commencing on the date hereof and ending on
the Closing Date, Parent shall, upon reasonable notice, afford to the Company
and the Company's counsel, accountants and other authorized representatives,
reasonable access during normal business hours to the properties, personnel,
advisors, books and records of Parent and its Subsidiaries in order that they
may have the opportunity to make such investigations as they shall desire of the
affairs of Parent and its Subsidiaries; such investigation shall not, however,
affect the representations and warranties made in this Agreement. Parent agrees
to cause its officers and employees to furnish such additional financial and
operating data and other information and respond to such inquiries as the
Company shall from time to time request.
SECTION 4.4. CONFIDENTIALITY. Information obtained by Parent and the
Company pursuant to this Agreement shall be subject to the provisions of the
Confidential Disclosure Agreement between the Company and Parent dated as of May
21, 1997, as amended (the "Confidential Disclosure Agreement").
SECTION 4.5. REGISTRATION STATEMENT/JOINT PROXY STATEMENT; QUOTATION
ON NASDAQ NATIONAL MARKET. (a) As promptly as practicable after the execution of
this Agreement, the Company and Parent shall prepare and file with the
Commission preliminary proxy materials which shall constitute the preliminary
Joint Proxy Statement and a preliminary prospectus with respect to the Parent
Shares to be issued in connection with the Merger. In connection with the Joint
Proxy Statement, counsel to the Company and counsel to Parent shall each provide
their opinion with respect to the tax disclosure contained therein for filing as
exhibits to the Registration Statement. At or prior to the filing of the
preliminary Joint Proxy Statement, the Company and Parent shall provide to such
counsel such tax representation letters as may be reasonably requested. As
promptly as practicable after comments are received from the Commission with
respect to the preliminary proxy materials and after the furnishing by the
Company and Parent of all information required to be contained therein
(including, without limitation, financial statements and supporting schedules
and certificates and reports of independent public accountants), the Company and
Parent shall file with the Commission the definitive Joint Proxy Statement and
Parent shall file with the Commission the Registration Statement, which Joint
Proxy Statement and Registration Statement shall each comply in all material
respects with the applicable requirements of the Exchange Act and Securities
Act, respectively, and the applicable rules and regulations of the Commission
thereunder. Parent and the Company shall use their reasonable efforts to cause
the Registration Statement to become effective as soon
-48-
<PAGE>
thereafter as practicable. The definitive Joint Proxy Statement shall contain
the opinion of Morgan Stanley & Co. Incorporated referred to in Section 3.1(q)
of this Agreement.
(b) The Company and Parent shall cause the Joint Proxy Statement to
be mailed to their respective stockholders and, if necessary, after the Joint
Proxy Statement shall have been so mailed, promptly circulate amended,
supplemental or supplemented proxy material and, if required in connection
therewith, resolicit proxies.
(c) Each of Parent and Sub, on the one hand, and the Company, on the
other hand, warrants to the other that the information provided and to be
provided by Parent and Sub and the Company, respectively (or incorporated by
reference to filings made with the Commission by Parent and the Company,
respectively), for use in each of the Registration Statement, on the date the
Registration Statement becomes effective, and the Joint Proxy Statement, on the
date the Joint Proxy Statement is filed with the Commission and on the date it
is first mailed to the Company's stockholders and the date it is first mailed to
Parent's stockholders, shall not contain any untrue statement of a material fact
or omit to state any material fact necessary in order to make the statements
therein, in light of the circumstances under which they were made, not
misleading. Each of Parent and Sub, on the one hand, and the Company, on the
other, shall notify the other parties promptly of the receipt of any comments by
the Commission and of any request by the Commission for amendments or
supplements to the preliminary Joint Proxy Statement, the Joint Proxy Statement
or the Registration Statement or for additional information, and shall supply
one another with copies of all correspondence with the Commission with respect
to any of the foregoing. If at any time prior to the Special Meeting, any event
should occur relating to Parent or Sub (or any of their respective affiliates,
directors or officers) which should be described in an amendment or supplement
to the Joint Proxy Statement or the Registration Statement, Parent shall
promptly inform the Company. If at any time prior to the Parent Stockholders'
Meeting, any event should occur relating to the Company, its Subsidiaries or any
of their respective affiliates, directors or officers which should be described
in an amendment or supplement to the Joint Proxy Statement or the Registration
Statement, the Company shall promptly inform Parent. Whenever any event occurs
which should be described in an amendment or supplement to the Joint Proxy
Statement or the Registration Statement, Parent and the Company shall, upon
learning of such event, cooperate with each other promptly to file and clear
with the Commission and, if applicable, mail such amendment or supplement to the
stockholders of the Company and Parent.
(d) Parent shall use its best efforts to obtain approval for
quotation on the Nasdaq National Market, upon
-49-
<PAGE>
official notice of issuance, of the Parent Shares to be issued pursuant to the
Merger.
(e) Parent and the Company shall make all necessary filings with
respect to the Merger under the Securities Act and the Exchange Act and the
rules and regulations thereunder and under applicable blue sky or similar laws
and shall use their reasonable efforts to obtain required approvals and
clearances with respect thereto; PROVIDED, HOWEVER, that Parent shall not be
required (i) to qualify to do business as a foreign corporation in any
jurisdiction in which it is not now qualified or (ii) to file a general consent
to service of process in any jurisdiction in which it is not now required to do
so.
SECTION 4.6. EMPLOYEE BENEFITS. Immediately after the Effective
Time, Parent or the Surviving Corporation shall cause to be provided to the
Surviving Corporation's employees for not less than one year from and after the
Closing Date Current Benefits (as defined below) that are, in the aggregate,
substantially as favorable to such employees as the Current Benefits available
to them as of the date of this Agreement under the Employee Benefit Plans.
Without limiting the generality of the foregoing, for not less than one year
from and after the Closing Date (a) all Surviving Corporation employees will
continue to be provided with the same level of severance benefits provided to
them immediately prior to the date of this Agreement under those severance plans
specified in Schedule 3.1(j) delivered to Parent by the Company prior to the
execution of this Agreement, of which the Company has provided Parent with
accurate and complete copies prior to the date hereof and (b) to the extent that
any employee of the Surviving Corporation participates in any Parent Employee
Benefit Plan after the Effective Time, Parent shall use reasonable efforts to
ensure (i) that such employee receives credit for his or her service with the
Company, to the same extent as such service was credited under any similar
Employee Benefit Plan immediately prior to the Effective Time, for purposes of
determining eligibility to participate in and vesting under, and for purposes of
calculating the benefits under, such Parent Employee Benefit Plan, (ii) that any
pre-existing condition limitations, waiting periods or similar limitations under
such Parent Employee Benefit Plan are waived, and (iii) that such employee
receives credit for any co-payments previously made and any deductible
previously satisfied under any similar Employee Benefit Plan. For purposes of
this Section 4.6, "Current Benefits" shall refer to benefits available under
Employee Benefit Plans or Parent Employee Benefit Plans, other than benefits
available under stock option plans, stock purchase plans and other equity-based
benefit plans.
SECTION 4.7. STOCKHOLDER APPROVALS; RECOMMENDATIONS. (a) The
Company, acting through its Board of Directors, shall (i) call, give notice of,
convene and hold a special meeting of the holders of Company Common Stock for
the purpose of voting
-50-
<PAGE>
upon this Agreement and the Merger (the "Special Meeting") and (ii) subject to
Section 4.16(b), include in the Joint Proxy Statement the recommendation of its
Board of Directors that holders of Company Common Stock approve and adopt this
Agreement and approve the Merger at the Special Meeting. The Special Meeting
will be held as promptly as practicable after the Registration Statement is
declared effective under the Securities Act. The Company shall ensure that the
Special Meeting is called, noticed, convened, held and conducted, and that all
proxies solicited, in connection with the Special Meeting are solicited in
compliance with all applicable laws, regulations, orders, judgments and decrees.
The Company's obligation to call, give notice of, convene and hold the Special
Meeting in accordance with this Section 4.7(a) shall not be limited or otherwise
affected by the disclosure, announcement, commencement, submission or making of
any Superior Proposal or other Takeover Proposal, or by any withdrawal or
modification of the recommendation of the Board of Directors of the Company with
respect to the Merger. The Company shall not be permitted to delay, adjourn,
postpone or reschedule the Special Meeting, or delay the vote of the Company's
stockholders on the Merger, without Parent's prior written consent (which
consent will not be unreasonably withheld or delayed if the need for the delay,
adjournment, postponement or rescheduling of the Special Meeting or the delay in
such vote is attributable solely to factors outside the Company's control).
(b) Parent, acting through its Board of Directors, shall (i) call,
give notice of, convene and hold a special meeting of its stockholders for the
purpose of voting upon the issuance of Parent Shares in the Merger (the "Parent
Stockholders' Meeting"), and (ii) include in the Joint Proxy Statement the
recommendation of its Board of Directors that its stockholders vote in favor of
the issuance of Parent Shares in the Merger at the Parent Stockholders' Meeting.
The Parent Stockholders' Meeting will be held as promptly as practicable after
(and, to the extent feasible, on the same day as) the Special Meeting. Parent
shall ensure that the Parent Stockholders' Meeting is called, noticed, convened,
held and conducted, and that all proxies solicited in connection with the Parent
Stockholders' Meeting are solicited, in compliance with all applicable laws,
regulations, orders, judgments and decrees.
(c) Notwithstanding anything to the contrary contained in this
Section 4.7, the Company's Board of Directors shall be permitted to withdraw or
modify its recommendation in favor of the Merger only in accordance with the
provisions of Section 4.16(b).
SECTION 4.8. STOCK OPTIONS. The Company shall take such actions
as may be permitted under the Stock Option Plans to effect the actions
described in Section 2.5.
-51-
<PAGE>
SECTION 4.9. LETTERS OF THE COMPANY'S ACCOUNTANTS. The Company shall
diligently seek to cause to be delivered to Parent a letter of Ernst & Young
LLP, the Company's independent auditors, dated a date within two business days
before the date of the Proxy Statement and a second bring-down letter, dated a
date within two business days before the Effective Time, in each case addressed
to Parent and its board of directors, in form and substance reasonably
satisfactory to Parent and customary in scope and substance for letters
delivered by independent public accountants in connection with registration
statements similar to the Registration Statement. The Company shall diligently
seek to cause Ernst & Young LLP to deliver to Parent and the Company a letter
(which may contain customary qualifications and assumptions), dated as of the
Closing Date, confirming the concurrence of Ernst & Young LLP with the Company's
management's conclusion that no conditions exist related to the Company that
would preclude Parent from accounting for the Merger as a pooling of interests
if the Merger is consummated in accordance with this Agreement.
SECTION 4.10. LETTERS OF PARENT'S ACCOUNTANTS. Parent shall
diligently seek to cause to be delivered to the Company a letter of Ernst &
Young LLP, Parent's independent auditors, dated a date within two business days
before the date on which the Registration Statement shall become effective and a
second bring-down letter, dated a date within two business days before the
Effective Time, in each case addressed to the Company and its board of
directors, in form and substance reasonably satisfactory to the Company and
customary in scope and substance for letters delivered by independent public
accountants in connection with registration statements similar to the
Registration Statement. Parent and the Company shall diligently seek to cause
Ernst & Young LLP to deliver the letter referred to in Section 5.1(h).
SECTION 4.11. NOTICES OF CERTAIN EVENTS. Each party hereto shall
promptly notify the other parties of:
(a) the receipt by such party or any of such party's Subsidiaries of
any notice or other communication from any Person alleging that the
consent of such Person is or may be required in connection with the
transactions contemplated by this Agreement;
(b) the receipt by such party or any of such party's Subsidiaries of
any notice or other communication from any Governmental Entity in
connection with the transactions contemplated by this Agreement;
(c) such party's obtaining knowledge of any actions, suits, claims,
investigations or proceedings commenced or threatened against, relating to
or involving or otherwise affecting any of Parent, Sub or the Company, as
the case may
-52-
<PAGE>
be, or any of their respective Subsidiaries which relate to the
consummation of the transactions contemplated by this Agreement; and
(d) such party's obtaining knowledge of the occurrence, or failure
to occur, of any event which occurrence or failure to occur will be likely
to cause (A) any representation or warranty contained in this Agreement to
be untrue or inaccurate in any material respect, or (B) any material
failure of any party to comply with or satisfy any covenant, condition or
agreement to be complied with or satisfied by it under this Agreement;
PROVIDED, HOWEVER, that no such notification shall affect the
representations, warranties or obligations of the parties or the
conditions to the obligations of the parties hereunder.
SECTION 4.12. HSR ACT. The Company and Parent shall, as soon as
practicable after the date of this Agreement, file Notification and Report Forms
under the HSR Act with the Federal Trade Commission (the "FTC") and the
Antitrust Division of the Department of Justice (the "Antitrust Division") and
shall use their reasonable efforts to respond as promptly as practicable to all
inquiries received from the FTC or the Antitrust Division for additional
information or documentation.
SECTION 4.13. INDEMNIFICATION; OFFICERS' AND DIRECTORS' Insurance.
(a) From and after the Effective Time, the Surviving Corporation shall
indemnify, defend and hold harmless each person who is now, or who becomes prior
to the Effective Time, an officer or director of the Company (the "Indemnified
Parties") against all losses, expenses, claims, damages, liabilities, costs,
expenses, judgments or amounts that are paid in settlement with the approval of
the indemnifying party (which approval will not be unreasonably withheld)
arising out of any action or omission of such Indemnified Party in his or her
capacity as an officer or director of the Company in connection with the
transactions contemplated by this Agreement to the fullest extent provided for
under the Company's Certificate of Incorporation and By Laws as in effect as of
the date hereof or permitted or required by applicable law, including without
limitation the advancement of expenses. Parent agrees that all rights to
indemnification existing in favor of the Indemnified Parties as provided in the
Company's Certificate of Incorporation or By-Laws, as in effect as of the date
hereof, with respect to matters occurring through the Effective Time, shall
survive the Merger and shall continue in full force and effect for a period of
not less than six years from the Effective Time, and Parent hereby guarantees
the due and prompt performance in full of such indemnification obligations of
the Surviving Corporation. Parent agrees to use its best efforts to cause the
Surviving Corporation to maintain in effect for not less than three years after
the Effective Time the current policies of directors' and officers' liability
insurance maintained by the
-53-
<PAGE>
Company with respect to matters occurring prior to the Effective Time; PROVIDED,
HOWEVER, that (i) the Surviving Corporation may substitute therefor policies of
at least the same coverage (with carriers comparable to the Company's existing
carriers) containing terms and conditions which are no less advantageous to the
Indemnified Parties and (ii) the Surviving Corporation shall not be required to
pay a premium at a rate for such insurance in excess of 200% of the annual
premium rate represented by the last premium paid prior to the date hereof, but
in such case shall purchase as much coverage as possible for such amount and
(iii) any or all of the Indemnified Parties shall have the right to provide
funds to the Surviving Corporation to fund premiums to the extent they exceed
such 200% level.
(b) The provisions of this Section 4.13 are intended for the benefit
of, and shall be enforceable by, each Indemnified Party and his or her heirs and
personal representatives.
SECTION 4.14. EFFORTS. Each of the Company, Parent and Sub shall,
and shall cause each of their respective Subsidiaries to, cooperate and use
their reasonable efforts to take, or cause to be taken, all appropriate action,
and to make, or cause to be made, all filings necessary, proper or advisable
under applicable laws and regulations to consummate and make effective the
transactions contemplated by this Agreement, including, without limitation,
their reasonable efforts to (i) obtain, prior to the Closing Date, all licenses,
permits, consents, approvals, authorizations, qualifications and orders of
governmental authorities and parties to contracts with the Company and its
Subsidiaries and Parent and its Subsidiaries and (ii) defend against and respond
to any action, suit, proceeding or investigation relating to the transactions
contemplated by this Agreement, in each case as are necessary for consummation
of the transactions contemplated by this Agreement and to fulfill the conditions
to the Merger.
SECTION 4.15. RULE 145. Contemporaneously with the execution and
delivery of this Agreement, the Company is delivering to Parent a list of names
and addresses of those persons who are, in the Company's reasonable judgment,
"affiliates" (each such person, an "Affiliate") of the Company within the
meaning of Rule 145 of the rules and regulations promulgated under the
Securities Act. The Company shall use all reasonable efforts to deliver or cause
to be delivered to Parent, from each of the Affiliates of the Company identified
in the foregoing list (and from any Person who becomes, or could reasonably be
deemed to be, an Affiliate after the date of this Agreement), as promptly as
practicable after the date hereof (with respect to Persons identified on such
list), and no later than the date such Person becomes an Affiliate (with respect
to Persons who become Affiliates after the date hereof), an Affiliate Agreement
in the form attached hereto as Exhibit A (an "Affiliate Agreement"). Parent
shall be entitled to place
-54-
<PAGE>
legends as specified in such Affiliate Agreements on the certificates evidencing
any Parent Shares to be received by such Affiliates pursuant to the terms of
this Agreement, and to issue appropriate stop transfer instructions to the
transfer agent for the Parent Shares, consistent with the terms of such
Affiliate Agreements.
SECTION 4.16. NO SOLICITATION. (a) The Company shall not, nor shall
it permit any of its Subsidiaries to, nor shall it authorize or permit any
officer or director of, or any investment banker, attorney or other advisor or
representative ("Representative") of, the Company or any of its Subsidiaries to,
directly or indirectly, (i) solicit, initiate or encourage the submission or
announcement of any Takeover Proposal, (ii) participate in any discussions or
negotiations regarding, or furnish to any Person any information with respect or
in response to, or take any other action to facilitate any inquiries or the
making of any proposal that constitutes, or may reasonably be expected to lead
to, any Takeover Proposal; PROVIDED, HOWEVER, that if (1) neither the Company
nor any Subsidiary or Representative of the Company or any Subsidiary shall have
violated any of the restrictions set forth in this Section 4.16, (2) the Board
of Directors of the Company determines in good faith, based upon the advice of
outside counsel, that such action is required in order for the Board of
Directors of the Company to comply with its fiduciary duties to the Company's
stockholders under applicable law, and (3) the Company has given Parent the
notice referred to in Section 4.16(c) and at least two business days have
elapsed since the delivery to Parent of the notice and information referred to
in Section 4.16(c), then the Company may, prior to the adoption and approval of
this Agreement by the stockholders of the Company, in response to a Takeover
Proposal that has not been withdrawn and that (but for the inclusion of a "due
diligence condition" as part of such Takeover Proposal) constitutes a Superior
Proposal (as defined in Section 4.16(b)), furnish information with respect to
the Company to the Person who made such Takeover Proposal (but only information
that has been previously furnished by the Company to Parent or that the Company
simultaneously furnishes to both such Person and Parent) pursuant to a customary
confidentiality agreement (containing terms and provisions that are no less
favorable to and protective of the Company than the terms and provisions of the
Confidential Disclosure Agreement) and participate in discussions or
negotiations with such Person regarding such Takeover Proposal. Without limiting
the foregoing, it is understood that any violation of the restrictions set forth
in the preceding sentence by any officer or director of the Company or any of
its Subsidiaries or any investment banker, attorney or other advisor or other
Representative of the Company or any of its Subsidiaries, whether or not such
Person is purporting to act on behalf of the Company or any of its Subsidiaries
or otherwise, shall be deemed to be a breach of this Section 4.16(a) by the
Company. The Company shall immediately cease and cause to be
-55-
<PAGE>
terminated any existing discussions or negotiations with any Person that relate
to any Takeover Proposal. For purposes of this Agreement, "Takeover Proposal"
means any (i) offer, inquiry or proposal for, relating to or contemplating a
merger, consolidation, amalgamation, share exchange, business combination,
issuance of securities, acquisition of securities, tender offer, exchange offer
or other similar transaction or series of transactions (A) in which the Company
or any of its material Subsidiaries is a constituent company, (B) in which a
Person or "group" (as defined in the Exchange Act and the rules promulgated
thereunder) of Persons directly or indirectly acquires the Company or any
material Subsidiary of the Company or more than 20% of the Company's business or
directly or indirectly acquires beneficial or record ownership of securities
representing, or exchangeable for or convertible into, more than 20% of the
outstanding securities of any class of voting securities of the Company or any
material Subsidiary of the Company, or (C) in which the Company or any material
Subsidiary of the Company issues securities representing more than 20% of the
outstanding securities of any class of voting securities of the Company or such
material Subsidiary of the Company, or (ii) offer, inquiry or proposal for,
relating to or contemplating a transaction (including any joint venture,
collaboration or similar transaction) involving the sale, lease, exchange,
transfer, license, acquisition or disposition or sharing of control of any
material portion of the intellectual property rights or other rights or assets
of the Company or any material Subsidiary of the Company, other than the
transactions contemplated by this Agreement.
(b) Neither the Board of Directors of the Company nor any committee
thereof shall (i) withdraw or modify, or propose or resolve to withdraw or
modify, in a manner adverse to Parent or Sub, the approval or recommendation by
such Board of Directors or any such committee of this Agreement or the Merger,
(ii) approve or recommend, or propose to approve or recommend, any Takeover
Proposal or (iii) enter into any agreement or letter of intent with respect to
any Takeover Proposal. Notwithstanding the foregoing, in the event that, prior
to the adoption and approval of this Agreement by the stockholders of the
Company, (i) the Board of Directors of the Company receives a Superior Proposal
that is not withdrawn, (ii) neither the Company nor any Subsidiary or
Representative of the Company or any Subsidiary shall have violated any of the
restrictions set forth in this Section 4.16, (iii) the Board of Directors of the
Company concludes in good faith, based upon the advice of its outside counsel,
that, in light of such Superior Proposal, the withdrawal or modification of such
recommendation is required in order for the Board of Directors of the Company to
comply with its fiduciary obligations to the Company's stockholders under
applicable law, (iv) the Company shall have provided Parent with at least two
business days' prior notice of any meeting of the Company's Board of Directors
at which such Board of Directors is
-56-
<PAGE>
expected to consider such Superior Proposal, and (v) the Company's Board of
Directors does not withdraw or modify its recommendation in favor of the Merger
for at least two business days after the Company provides Parent with the name
of the Person making such Superior Proposal and a copy of such Superior
Proposal, then the Board of Directors may appropriately withdraw or modify its
approval or recommendation of this Agreement or the Merger. Nothing contained in
this Section 4.16 shall limit the Company's obligation to call, give notice of,
convene and hold the Special Meeting (regardless of whether the recommendation
of the Board of Directors of the Company shall have been withdrawn or modified).
For purposes of this Agreement, a "Superior Proposal" means any unsolicited bona
fide written offer made by a third party (1) to enter into a merger or business
combination with the Company whereby the shares of Company Common Stock and
other equity securities of the Company that are outstanding immediately before
such merger or business combination shall be exchanged for or converted into
shares of common stock and other equity securities of such third party that (on
a fully diluted basis) represent less than 50% of the common stock of such third
party outstanding immediately after such merger or business combination or (2)
to purchase for cash or a combination of cash and securities more than 50% of
the outstanding shares of Company Common Stock (provided that, in cases in which
holders of Company Common Stock receive common stock or other equity securities
of a third party, such common stock and other securities represent less than 50%
of the common stock (on a fully diluted basis) of such third party outstanding
immediately after such transaction), in either case on terms which the Board of
Directors of the Company determines in its good faith reasonable judgment (based
upon the written opinion of a financial advisor of nationally recognized
reputation) to be more favorable to the Company's stockholders than the Merger;
PROVIDED, HOWEVER, that any such offer shall not be deemed to be a "Superior
Proposal" if any financing required to consummate the transaction contemplated
by such offer is not committed and is not likely to be obtained by such third
party on a timely basis.
(c) In addition to the obligations of the Company set forth in
Sections 4.16(a) and (b) above, the Company shall promptly advise Parent orally
and in writing of any request for information or of any Takeover Proposal, or
any inquiry with respect to or which could reasonably be expected to lead to any
Takeover Proposal, the material terms and conditions of such request, Takeover
Proposal or inquiry, and the identity of the Person making any such Takeover
Proposal or inquiry. The Company shall use its best efforts to keep Parent fully
informed of the status and details of any such request, Takeover Proposal or
inquiry.
SECTION 4.17. TAX REORGANIZATION. Prior to the Closing Date, each
party shall use its best efforts to cause the Merger to qualify as a
reorganization within the meaning of
-57-
<PAGE>
Section 368(a) of the Code, and will not take any action reasonably likely to
cause the Merger not to so qualify.
SECTION 4.18. CONVERTIBLE DEBENTURES. From and after the Effective
Time, Parent shall cause the Surviving Corporation to comply with the provisions
of the indenture dated as of July 31, 1997 between the Company and IBJ Schroder
Bank & Trust Company, a New York banking corporation, as trustee, in its
entirety, including without limitation Sections 1311 and 1401 therein.
SECTION 4.19. WARRANTS. Prior to the Closing Date, the Company shall
comply with the provisions of each outstanding warrant to purchase Company
Common Stock. Without limiting the generality of the foregoing, the Company
shall, on a timely basis, provide all notices required under each such warrant.
ARTICLE V.
CONDITIONS PRECEDENT TO MERGER
SECTION 5.1. CONDITIONS PRECEDENT TO OBLIGATIONS OF PARENT, SUB AND
THE COMPANY. The respective obligations of Parent and Sub, on the one hand, and
the Company, on the other hand, to effect the Merger are subject to the
satisfaction or waiver (subject to applicable law) at or prior to the Effective
Time of each of the following conditions:
(a) APPROVAL OF STOCKHOLDERS. This Agreement, the Merger and related
transactions shall have been approved and adopted by the requisite vote or
consent of the stockholders of the Company in accordance with applicable
law and the Company's Certificate of Incorporation and By-Laws, and the
issuance of Parent Shares in the Merger shall have been duly approved by
the requisite vote or consent of the stockholders of Parent in accordance
with the applicable rules of the National Association of Securities
Dealers, Inc.
(b) HSR ACT. Any waiting period (and any extension thereof) under
the HSR Act applicable to the Merger shall have expired or been
terminated.
(c) NO RESTRAINTS. No preliminary or permanent injunction or other
order shall have been issued by any court or by any governmental or
regulatory agency, body or authority which enjoins, restrains or prohibits
the transactions contemplated hereby, including the consummation of the
Merger, or has the effect of making the Merger illegal and which is in
effect at the Effective Time (each party agreeing to use its reasonable
efforts to have any such injunction or order lifted).
-58-
<PAGE>
(d) STATUTES. No statute, rule, regulation, executive order, decree
or order of any kind shall have been enacted, entered, promulgated or
enforced by any court or governmental authority which prohibits the
consummation of the Merger or has the effect of making the Merger illegal
and which remains in effect at the Effective Time.
(e) NASDAQ NATIONAL MARKET QUOTATION. The Parent Shares issuable to
Company stockholders pursuant to this Agreement shall have been approved
for quotation on the Nasdaq National Market upon official notice of
issuance.
(f) EFFECTIVENESS OF REGISTRATION STATEMENT. The Registration
Statement shall have become effective in accordance with the provisions of
the Securities Act and shall not be the subject of any stop order or
proceedings seeking a stop order.
(g) MARKET EVENTS. There shall not have occurred and be continuing
any general suspension or limitation of trading in the Parent Shares
(exclusive, however, of any temporary suspension or pending and ensuing
public announcement) or in securities generally on the Nasdaq National
Market.
(h) ACCOUNTING TREATMENT. Parent shall have received a letter from
Ernst & Young LLP (which may contain customary qualifications and
assumptions) confirming the concurrence of Ernst & Young LLP with Parent's
management's conclusion as to the appropriateness of accounting for the
Merger as a pooling of interests if the Merger is consummated in
accordance with this Agreement.
SECTION 5.2. CONDITIONS PRECEDENT TO OBLIGATIONS OF PARENT AND SUB.
The obligations of Parent and Sub to effect the Merger are also subject to the
satisfaction or waiver, at or prior to the Effective Time, of each of the
following conditions:
(a) ACCURACY OF REPRESENTATIONS AND WARRANTIES. All representations
and warranties of the Company contained herein shall be true and correct
in all material respects as of the date hereof and at and as of the
Closing, with the same force and effect as though made on and as of the
Closing Date unless the failure of such representations and warranties to
be true and correct in all material respects does not, individually or in
the aggregate, materially and adversely affect the value of the Company
and its Subsidiaries taken as a whole, and Parent and Sub shall have
received a certificate to this effect from a senior financial officer of
the Company.
(b) PERFORMANCE BY COMPANY. Except as otherwise agreed in writing,
the Company shall have performed in all
-59-
<PAGE>
material respects all obligations and agreements, and complied in all
material respects with all covenants, contained in this Agreement to be
performed or complied with by it on or prior to the Closing Date, and
Parent and Sub shall have received a certificate to this effect from a
senior financial officer of the Company.
(c) AFFILIATE AGREEMENTS. Each Person who could reasonably be deemed
to be an "affiliate" of the Company (as that term is used in Rule 145
under the Securities Act) shall have executed and delivered to Parent an
Affiliate Agreement.
(d) TAX OPINION. Parent shall have received the opinion of Cooley
Godward LLP, counsel to Parent, to the effect that the Merger will be
treated for United States federal income tax purposes as a reorganization
within the meaning of Section 368(a) of the Code; PROVIDED, HOWEVER, that
if Cooley Godward LLP does not render such opinion or withdraws or
modifies such opinion, the condition set forth in this Section 5.2(d)
shall nonetheless be deemed to be satisfied if Willkie Farr & Gallagher
renders such opinion to Parent. In delivering its opinion, counsel shall
be entitled to rely on the tax representation letters delivered pursuant
to Section 4.5(a).
(e) ACCOUNTANTS' LETTERS. Parent shall have received from Ernst &
Young LLP the letters referred to in Section 4.9.
(f) CONSENTS. All material consents required to be obtained (from
Governmental Entities or other Persons) in connection with the Merger and
the other transactions contemplated by this Agreement (including, without
limitation, the consents identified in Schedule 3.1(d)(4)) shall have been
obtained and shall be in full force and effect.
(g) NO GOVERNMENTAL LITIGATION. There shall not be pending and there
shall not have been threatened any action, suit or proceeding in which a
Governmental Entity is or is threatened to become a party or is otherwise
involved: (a) challenging or seeking to restrain or prohibit the
consummation of the Merger or any of the other transactions contemplated
by this Agreement; (b) relating to the Merger and seeking to obtain from
Parent or any of its Subsidiaries, or the Company or any of the Company's
Subsidiaries, any damages or other relief that are or are likely to be
material to Parent; (c) seeking to prohibit or limit in any material
respect Parent's ability to vote, receive dividends with respect to or
otherwise exercise ownership rights with respect to the stock of the
Surviving Corporation; or (d) which would materially and adversely
-60-
<PAGE>
affect the right of Parent, the Surviving Corporation or any of the
Surviving Corporation's Subsidiaries to own the assets or operate the
business of the Surviving Corporation and the Surviving Corporation's
Subsidiaries.
SECTION 5.3. CONDITIONS PRECEDENT TO OBLIGATION OF THE COMPANY. The
obligation of the Company to effect the Merger is also subject to the
satisfaction or waiver, at or prior to the Effective Time, of each of the
following conditions:
(a) ACCURACY OF REPRESENTATIONS AND WARRANTIES. All representations
and warranties of Parent and Sub contained herein shall be true and
correct in all material respects as of the date hereof and at and as of
the Closing, with the same force and effect as though made on and as of
the Closing Date unless the failure of such representations and warranties
to be true and correct in all material respects does not, individually or
in the aggregate, materially and adversely affect the value of Parent and
its Subsidiaries taken as a whole, and the Company shall have received a
certificate to this effect from a senior financial officer of Parent.
(b) PERFORMANCE BY PARENT AND SUB. Except as otherwise agreed in
writing, each of Parent and Sub shall have performed in all material
respects all obligations and agreements, and complied in all material
respects with all covenants, contained in this Agreement to be performed
or complied with by it on or prior to the Closing Date, and the Company
shall have received a certificate to this effect from a senior financial
officer of Parent.
(c) TAX OPINION. The Company shall have received the opinion of
Willkie Farr & Gallagher, counsel to the Company, to the effect that the
Merger will be treated for United States federal income tax purposes as a
reorganization within the meaning of Section 368(a) of the Code; PROVIDED,
HOWEVER, that if Willkie Farr & Gallagher does not render such opinion or
withdraws or modifies such opinion, the condition set forth in this
Section 5.3(c) shall nonetheless be deemed to be satisfied if Cooley
Godward LLP renders such opinion to the Company. In delivering its
opinion, counsel shall be entitled to rely on the tax representation
letters delivered pursuant to Section 4.5(a).
(d) REGISTRATION RIGHTS AGREEMENT. At or prior to the
Effective Time, Parent shall have executed and delivered a Registration
Rights Agreement substantially in the form of Exhibit B hereto with
Warburg, Pincus Investors, L.P. and Warburg, Pincus Capital Partners
Liquidating Trust.
(e) UNDERTAKINGS. Parent shall have delivered to the Company copies
of undertakings executed by each of its
-61-
<PAGE>
executive officers and directors in substantially the form of Exhibit C
hereto.
ARTICLE VI.
TERMINATION AND ABANDONMENT
SECTION 6.1. TERMINATION. This Agreement may be terminated and the
transactions contemplated hereby may be abandoned, at any time prior to the
Effective Time, whether before or after approval of the Merger by the
stockholders of the Company:
(a) by mutual consent of the Company, on the one hand, and of Parent
and Sub, on the other hand;
(b) by either Parent or the Company, if the Effective Time shall not
have occurred by September 30, 1999 (unless the failure to consummate the
Merger is attributable to a failure on the part of the party seeking to
terminate this Agreement to perform any material obligation required to be
performed by such party at or prior to the Effective Time);
(c) by Parent, if the required approval of the Company's
stockholders shall not have been obtained by reason of the failure to
obtain the required vote at a duly held meeting of stockholders or at any
adjournment thereof;
(d) by either Parent or the Company if the required approval of
Parent's stockholders of the issuance of Parent Shares in the Merger shall
not have been obtained by reason of the failure to obtain the required
vote at a duly held meeting of stockholders or at any adjournment thereof;
(e) by either Parent or the Company, if there shall be any law or
regulation of any Governmental Entity that makes consummation of the
Merger illegal or otherwise prohibited or if any judgment, injunction,
order or decree of any Governmental Entity prohibiting such transaction is
entered and such judgment, injunction, order or decree shall have become
final and nonappealable;
(f) by either Parent or the Company, if there has been a breach of
any covenant or a breach of any representation or warranty on the part of
the other, such that the condition set forth in Section 5.2(a) or Section
5.2(b) (in the case of any termination by Parent) or the condition set
forth in Section 5.3(a) or Section 5.3(b) (in the case of any termination
by the Company) would not be satisfied; PROVIDED that any such breach of a
covenant or representation or warranty has not been cured within 15
-62-
<PAGE>
business days following receipt by the breaching party of notice hereunder
of such breach;
(g) by Parent, if the Special Meeting is canceled or is otherwise
not held or if a final vote of the Company's stockholders has not been
taken with respect to the Merger prior to September 15, 1999, except as a
result of a judgment, injunction, order or decree of any competent
authority or events or circumstances beyond the reasonable control of the
Company; PROVIDED, HOWEVER, that such termination under this clause (g)
shall not relieve the Company of its fee obligations under Section 7.1(c)
hereof; or
(h) by Parent, if (i) the Board of Directors of the Company shall
have withdrawn or modified in a manner adverse to Parent its approval or
recommendation to the Company's stockholders of this Agreement or the
Merger; (ii) the Company shall have failed to include in the Joint Proxy
Statement the recommendation of the Board of Directors of the Company in
favor of the adoption and approval of this Agreement and the approval of
the Merger; (iii) the Board of Directors of the Company shall have
approved, endorsed or recommended any Takeover Proposal; (iv) a tender or
exchange offer relating to securities of the Company shall have been
commenced and the Company shall not have sent to its security holders,
within ten business days after the commencement of such tender or exchange
offer, a statement disclosing that the Company recommends rejection of
such tender or exchange offer; (v) the Company breaches any of its
obligations under Section 4.16 of this Agreement; (vi) subsequent to the
date of this Agreement, a Person or "group" (as defined in the Exchange
Act and the rules promulgated thereunder) of Persons directly or
indirectly becomes the beneficial or record owner of securities
representing, or exchangeable for or convertible into, at least 20% of the
outstanding securities of any class of voting securities of the Company or
any material Subsidiary of the Company; (vii) a Person or group of Persons
that, as of the date of this Agreement, directly or indirectly is the
beneficial or record owner of securities representing, or exchangeable for
or convertible into, 20% or more of the outstanding securities of any
class of voting securities of the Company or any material Subsidiary of
the Company, directly or indirectly acquires beneficial or record
ownership of an additional 5% of the outstanding securities of any class
of voting securities of the Company or any material Subsidiary of the
Company; or (viii) the Company or the Company's Board of Directors or any
committee thereof shall have resolved to do or permit any of the
foregoing; PROVIDED, HOWEVER, that such termination under this clause (h)
shall not relieve the Company of its fee obligations under Section 7.1(c)
hereof. For purposes of clause (vii)
-63-
<PAGE>
of this Section 6.1(h), a group shall be deemed to include, without
limitation, all Persons who file a Statement or Statements on Schedule 13D
as a group, whether or not such Persons disclaim the existence of a group
and whether or not such Persons disclaim beneficial ownership of any
securities.
SECTION 6.2. EFFECT OF TERMINATION. In the event of the termination
of this Agreement pursuant to Section 6.1 hereof by Parent or Sub, on the one
hand, or the Company, on the other hand, written notice thereof shall forthwith
be given to the other party or parties specifying the provision hereof pursuant
to which such termination is made, and this Agreement shall become void and have
no effect, and there shall be no liability hereunder on the part of Parent, Sub
or the Company, except that Sections 3.1(p), 3.2(l), 4.4, this Section 6.2 and
Article VII hereof shall survive any termination of this Agreement. Nothing in
this Section 6.2 shall relieve any party to this Agreement of liability for
breach of this Agreement or for representations which were incorrect when made.
ARTICLE VII.
MISCELLANEOUS
SECTION 7.1. FEES AND EXPENSES. (a) Except as provided below in this
Section 7.1, all fees and expenses incurred in connection with the Merger, this
Agreement and the transactions contemplated by this Agreement shall be paid by
the party (the Company, on the one hand, or Parent and Sub, on the other hand)
incurring such fees or expenses, whether or not the Merger is consummated;
PROVIDED, HOWEVER, that (i) Parent and the Company shall share equally all fees
and expenses, other than attorneys' fees, incurred in connection with (A) the
filing, printing and mailing of the Registration Statement and the Joint Proxy
Statement and any amendments or supplements thereto and (B) the filing by Parent
and the Company of the premerger notification and report forms relating to the
Merger under the HSR Act.
(b) If this Agreement is terminated by Parent pursuant to
Sections 6.1(c), 6.1(f), 6.1(g) or 6.1(h), the Company shall pay, or cause to be
paid, in same day funds to Parent upon demand, all actual out-of-pocket costs
and expenses of Parent and Sub incurred in connection with this Agreement and
the transactions contemplated hereby, including, without limitation, legal,
professional and service fees and expenses. If this Agreement is terminated by
the Company pursuant to Section 6.1(f), Parent shall pay, or cause to be paid,
in same day funds to the Company upon demand, all actual out-of-pocket costs and
expenses of the Company incurred in connection with this Agreement and the
transactions contemplated hereby,
-64-
<PAGE>
including, without limitation, legal, professional and service fees and
expenses.
(c) The Company shall pay, or cause to be paid, in same day funds to
Parent upon demand (in addition to any amount required to be paid pursuant to
Section 7.1(a) or 7.1(b)) a fee of $18,000,000 if:
(i) this Agreement is terminated pursuant to Section 6.1(c) and at
or prior to the time of such termination a Takeover Proposal shall have been
disclosed, announced, commenced, submitted or made; or
(ii) this Agreement is terminated by Parent pursuant to Section
6.1(g) or 6.1(h).
(d) Parent shall pay, or cause to be paid, in same day funds to the
Company upon demand (in addition to any amount required to be paid pursuant to
Section 7.1(a)) a fee of $5,000,000 if (i) this Agreement is terminated by the
Company pursuant to Section 6.1(d) and (ii) there shall not have occurred, and
no facts, events or circumstances shall have been publicly announced that are
likely to result in, a material adverse change in the Condition of the Company
and its Subsidiaries taken as a whole.
SECTION 7.2. REPRESENTATIONS, WARRANTIES AND AGREEMENTS. The
respective representations and warranties of the Company, on the one hand, and
Parent and Sub, on the other hand, contained herein or in any certificates or
other documents delivered prior to or at the Closing shall not be deemed waived
or otherwise affected by any investigation made by any party. Each and every
such representation and warranty and all agreements contained herein shall
expire with, and be terminated and extinguished by, the Closing and thereafter
none of the Company, Parent or Sub shall be under any liability whatsoever with
respect to any such representation or warranty or agreement except those
contained in Sections 2.2, 2.3, 2.5, 4.4, 4.13 and Article VII. This Section 7.2
shall have no effect upon any other obligation of the parties hereto, whether to
be performed before or after the Effective Time.
SECTION 7.3. EXTENSION; WAIVER. At any time prior to the Effective
Time, the parties hereto, by action taken by or on behalf of the respective
Boards of Directors of the Company, Parent or Sub, may (i) extend the time for
the performance of any of the obligations or other acts of the other parties
hereto, (ii) waive any inaccuracies in the representations and warranties
contained herein by any other applicable party or in any document, certificate
or writing delivered pursuant hereto by any other applicable party or (iii)
waive compliance with any of the agreements or conditions contained herein. Any
agreement on the part of any party to any such extension or waiver shall be
valid
-65-
<PAGE>
only if set forth in an instrument in writing signed on behalf of such party.
Except as provided in this Agreement, no action taken pursuant to this
Agreement, including, without limitation, any investigation by or on behalf of
any party, shall be deemed to constitute a waiver by the party taking such
action of compliance with any representations, warranties, covenants or
agreements contained in this Agreement. The waiver by any party hereto of a
breach of any provision hereunder shall not operate or be construed as a waiver
of any prior or subsequent breach of the same or any other provision hereunder.
SECTION 7.4. PUBLIC ANNOUNCEMENTS. The Company, on the one hand, and
Parent and Sub, on the other hand, agree to consult promptly with each other
prior to issuing any press release or otherwise making any public statement with
respect to the transactions contemplated hereby and shall not issue any such
press release or make any such public statement prior to such consultation and
review by the other party of a copy of such release or statement (the comments
of such party to be given reasonable consideration), unless such disclosure is
required by applicable law or the rules or regulations of any applicable
securities exchange or the Nasdaq National Market.
SECTION 7.5. NOTICES. All notices, requests, demands, waivers and
other communications required or permitted to be given under this Agreement
shall be in writing and shall be deemed to have been duly given if delivered in
Person or mailed, certified or registered mail with postage prepaid, or sent by
telex, telegram or telecopier, as follows:
if to the Company, to it at:
NeXstar Pharmaceuticals, Inc.
3035 Centre Green Drive
Boulder, CO 80301
Attention: Chief Financial Officer
Telecopy No.: (303) 413-5311
with a copy to:
Willkie Farr & Gallagher
787 Seventh Avenue
New York, New York 10019
Attention: Peter H. Jakes, Esq.
Telecopy No.: (212) 728-8111
if to either Parent or Sub, to it at:
Gilead Sciences, Inc.
333 Lakeside Drive
Foster City, CA 94404
Attention: General Counsel
Telecopy No.: (650) 522-5622
-66-
<PAGE>
with a copy to:
Cooley Godward LLP
Five Palo Alto Square
3000 El Camino Real
Palo Alto, CA 94306-2155
Attention: Richard E. Climan, Esq.
Telecopy No.: (650) 857-0663
or to such other Person or address as any party shall specify by notice in
writing to each of the other parties. All such notices, requests, demands,
waivers and communications shall be deemed to have been received on the date of
delivery unless mailed, in which case on the third business day (fifth business
day, if mailed outside the country of the recipient) after the mailing thereof
except for a notice of a change of address, which shall be effective only upon
receipt thereof.
SECTION 7.6. ENTIRE AGREEMENT. This Agreement, the schedules and the
exhibits and other documents referred to herein or delivered pursuant hereto
collectively contain the entire understanding of the parties hereto with respect
to the subject matter contained herein and therein and supersede all prior
agreements and understandings, oral and written, with respect thereto; PROVIDED,
HOWEVER, that the Confidential Disclosure Agreement is not superseded by this
Agreement and shall remain in full force and effect in accordance with its
terms.
SECTION 7.7. BINDING EFFECT; BENEFIT; ASSIGNMENT. This Agreement
shall inure to the benefit of and be binding upon the parties hereto and their
respective successors and permitted assigns, but neither this Agreement nor any
of the rights, interest or obligations hereunder shall be assigned by any of the
parties hereto without the prior written consent of the other parties.
Notwithstanding anything contained in this Agreement to the contrary, nothing in
this Agreement, expressed or implied, is intended to confer on any Person other
than the parties hereto or their respective successors and assigns any rights,
remedies, obligations or liabilities under or by reason of this Agreement;
provided that the Indemnified Parties shall be third-party beneficiaries of
Parent's agreement contained in Section 4.13 hereof.
SECTION 7.8. AMENDMENT AND MODIFICATION. Subject to applicable law,
this Agreement may be amended, modified and supplemented, or provisions hereof
waived, in writing by the parties hereto in any and all respects before the
Effective Time (notwithstanding any stockholder approval), by action taken by
the respective Boards of Directors of Parent, Sub and the Company or by the
respective officers authorized by such Boards of Directors, PROVIDED, HOWEVER,
that after any such stockholder approval, no amendment, modification, supplement
or waiver shall be made which by law requires further approval by such
-67-
<PAGE>
stockholders without such further approval. This Agreement may not be amended
except by an instrument in writing signed on behalf of each of the parties
hereto.
SECTION 7.9. FURTHER ACTIONS. Each of the parties hereto agrees
that, subject to its legal obligations, it will use its reasonable efforts to
fulfill all conditions precedent specified herein, to the extent that such
conditions are within its control, and to do all things reasonably necessary to
consummate the transactions contemplated hereby.
SECTION 7.10. HEADINGS. The descriptive headings of the several
Articles and Sections of this Agreement are inserted for convenience only, do
not constitute a part of this Agreement and shall not affect in any way the
meaning or interpretation of this Agreement.
SECTION 7.11. COUNTERPARTS. This Agreement may be executed in
several counterparts, each of which shall be deemed to be an original, and all
of which together shall be deemed to be one and the same instrument.
SECTION 7.12. APPLICABLE LAW. This Agreement and the legal relations
between the parties hereto shall be governed by and construed in accordance with
the laws of the State of Delaware, without regard to the conflict of laws rules
thereof.
SECTION 7.13. SEVERABILITY. If any term, provision, covenant or
restriction contained in this Agreement is held by a court of competent
jurisdiction or other authority to be invalid, void, unenforceable or against
its regulatory policy, the remainder of the terms, provisions, covenants and
restrictions contained in this Agreement shall remain in full force and effect
and shall in no way be affected, impaired or invalidated.
SECTION 7.14. ENFORCEMENT OF AGREEMENT. The parties hereto agree
that irreparable damage would occur in the event that any of the provisions of
this Agreement was not performed in accordance with its specific terms or was
otherwise breached. It is accordingly agreed that the parties shall be entitled
to an injunction or injunctions to prevent breaches of this Agreement and to
enforce specifically the terms and provisions hereof in any Delaware Court, this
being in addition to any other remedy to which they are entitled at law or in
equity.
SECTION 7.15. "PERSON" DEFINED. "Person" shall mean and include an
individual, a partnership, a joint venture, a corporation, a partnership, a
limited liability company, a trust, an unincorporated organization and a
government or other department or agency thereof.
SECTION 7.16. SUBMISSION TO JURISDICTION. With respect to any suit,
action or proceeding initiated by a party to
-68-
<PAGE>
this Agreement arising out of, under or in connection with this Agreement, the
Company, Parent and Sub each hereby submit to the non-exclusive jurisdiction of
any state or federal court sitting in the State of Delaware and irrevocably
waive, to the fullest extent permitted by law, any objection that they may now
have or hereafter obtain to the laying of venue in any such court in any such
suit, action or proceeding.
SECTION 7.17. SUBSIDIARIES. As used in this Agreement, the word
"Subsidiary" when used with respect to any party means any corporation or other
organization or entity, whether incorporated or unincorporated, of which such
party directly or indirectly owns or controls at least a majority of the
securities or other interests having by their terms ordinary voting power to
elect a majority of the board of directors or others performing similar
functions with respect to such corporation or other organization, or any
organization of which such party is a general partner.
-69-
<PAGE>
IN WITNESS WHEREOF, each of Parent, Sub and the Company has caused
this Agreement to be executed by their respective officers or directors
thereunto duly authorized, all as of the date first above written.
GILEAD SCIENCES, INC.
/s/ MARK L. PERRY
--------------------------------
By: Mark L. Perry
Title: Senior Vice President and
Chief Financial Officer
GAZELLE ACQUISITION SUB, INC.
/s/ MARK L. PERRY
--------------------------------
By: Mark L. Perry
Title: Secretary
NEXSTAR PHARMACEUTICALS, INC.
/s/ MICHAEL E. HART
--------------------------------
By: Michael E. Hart
Title: Vice President and Chief
Financial Officer
<PAGE>
VOTING AGREEMENT
THIS VOTING AGREEMENT is entered into as of February 28, 1999, by and
between GILEAD SCIENCES, INC., a Delaware corporation ("Parent"), and WARBURG,
PINCUS INVESTORS, L.P. ("Stockholder").
RECITALS
A. Parent, Gazelle Acquisition Sub, Inc., a Delaware corporation and a
wholly owned subsidiary of Parent ("Merger Sub"), and NeXstar Pharmaceuticals,
Inc., a Delaware corporation (the "Company"), are entering into an Agreement and
Plan of Merger of even date herewith (the "Merger Agreement") which provides
(subject to the conditions set forth therein) for the merger of Merger Sub into
the Company (the "Merger").
B. In order to induce Parent and Merger Sub to enter into the Merger
Agreement, Stockholder is entering into this Voting Agreement.
AGREEMENT
The parties to this Voting Agreement, intending to be legally bound, agree
as follows:
SECTION 1. CERTAIN DEFINITIONS.
For purposes of this Voting Agreement:
(a) "COMPANY COMMON STOCK" shall mean the common stock, par value
$.01 per share, of the Company.
(b) "EXPIRATION DATE" shall mean the earlier of (i) the date upon
which the Merger Agreement is validly terminated, or (ii) the date upon which
the Merger becomes effective.
(c) Stockholder shall be deemed to "OWN" or to have acquired
"OWNERSHIP" of a security if Stockholder: (i) is the record owner of such
security; or (ii) is the "beneficial owner" (within the meaning of Rule 13d-3
under the Securities Exchange Act of 1934) of such security.
(d) "PERSON" shall mean any (i) individual, (ii) corporation, limited
liability company, partnership, trust or other entity, or (iii) governmental
authority.
(e) "SUBJECT SECURITIES" shall mean: (i) all securities of the
Company (including all shares of Company Common Stock and all options, warrants
and other rights to acquire shares of Company Common Stock) Owned by Stockholder
as of the
<PAGE>
date of this Voting Agreement; and (ii) all additional securities of the Company
(including all additional shares of Company Common Stock and all additional
options, warrants and other rights to acquire shares of Company Common Stock) of
which Stockholder acquires Ownership during the period from the date of this
Voting Agreement through the Expiration Date.
(f) A Person shall be deemed to have a effected a "TRANSFER" of a
security if such Person directly or indirectly: (i) sells, pledges, encumbers,
grants an option with respect to, transfers, distributes or disposes of such
security or any interest in such security; or (ii) enters into an agreement or
commitment contemplating the possible sale of, pledge of, encumbrance of, grant
of an option with respect to, transfer of or disposition of such security or any
interest therein.
SECTION 2. TRANSFER OF SUBJECT SECURITIES.
2.1 TRANSFEREE OF SUBJECT SECURITIES TO BE BOUND BY THIS VOTING AGREEMENT.
Stockholder agrees that, during the period from the date of this Voting
Agreement through the Expiration Date, Stockholder shall not cause or permit any
Transfer of any of the Subject Securities to be effected (whether to
Stockholder's limited partners or to any other Person or Persons) unless each
Person to which any of such Subject Securities, or any interest in any of such
Subject Securities, is or may be Transferred shall have: (a) executed a
counterpart of this Voting Agreement and a proxy in the form attached hereto as
Exhibit A (with such modifications as Parent may reasonably request); and (b)
agreed to hold such Subject Securities (or interest in such Subject Securities)
subject to all of the terms and provisions of this Voting Agreement.
2.2 NO TRANSFER OF VOTING RIGHTS. Stockholder shall ensure that, during
the period from the date of this Voting Agreement through the Expiration Date:
(a) none of the Subject Securities is deposited into a voting trust; and (b) no
proxy is granted, and no voting agreement or similar agreement is entered into,
with respect to any of the Subject Securities.
SECTION 3. VOTING OF SHARES.
3.1 VOTING AGREEMENT. Stockholder agrees that, during the period from the
date of this Voting Agreement through the Expiration Date:
(a) at any meeting of stockholders of the Company, however called,
Stockholder shall (unless otherwise directed in writing by Parent) cause
all outstanding shares of Company Common Stock that are Owned by
Stockholder as of the record date fixed for such meeting to be voted in
favor of the approval and adoption of the Merger Agreement and the approval
of the Merger, and in favor of each of the other actions contemplated by
the Merger Agreement; and
2
<PAGE>
(b) in the event written consents are solicited or otherwise sought
from stockholders of the Company with respect to the approval or adoption
of the Merger Agreement, with respect to the approval of the Merger or with
respect to any of the other actions contemplated by the Merger Agreement,
Stockholder shall (unless otherwise directed in writing by Parent) cause to
be validly executed, with respect to all outstanding shares of Company
Common Stock that are Owned by Stockholder as of the record date fixed for
the consent to the proposed action, a written consent or written consents
to such proposed action.
3.2 PROXY; FURTHER ASSURANCES.
(a) Contemporaneously with the execution of this Voting Agreement:
(i) Stockholder shall deliver to Parent a proxy in the form attached to this
Voting Agreement as Exhibit A, which shall be irrevocable to the fullest extent
permitted by law, with respect to the shares referred to therein (the "Proxy");
and (ii) Stockholder shall cause to be delivered to Parent an additional proxy
(in the form attached hereto as Exhibit A) executed on behalf of the record
owner of any outstanding shares of Company Common Stock that are owned
beneficially (within the meaning of Rule 13d-3 under the Securities Exchange Act
of 1934), but not of record, by Stockholder.
(b) Stockholder shall, at Stockholder's own expense, perform such
further acts and execute such further documents and instruments as may
reasonably be required to vest in Parent the power to carry out and give effect
to the provisions of this Voting Agreement.
SECTION 4. WAIVER OF APPRAISAL RIGHTS.
Stockholder hereby irrevocably and unconditionally waives, and agrees to
cause to be waived and to prevent the exercise of, any rights of appraisal, any
dissenters' rights and any similar rights relating to the Merger or any related
transaction that Stockholder or any other Person may have by virtue of the
ownership of any Subject Securities.
SECTION 5. NO SOLICITATION.
During the period from the date of this Voting Agreement through the
Expiration Date, Stockholder shall not, nor shall Stockholder authorize or
permit any of Stockholder's Representatives (as defined in the Merger Agreement)
to, directly or indirectly: (i) solicit, initiate or encourage the submission or
announcement of any Takeover Proposal (as defined in the Merger Agreement);
(ii) participate in any discussions or negotiations regarding, or furnish to any
Person any information with respect or in response to, or take any other action
to facilitate any inquiries or the making of any proposal that constitutes, or
may reasonably be expected to lead to, any
3
<PAGE>
Takeover Proposal; or (iii) induce or encourage any other stockholder of the
Company to vote against, or to fail to vote in favor of, the approval and
adoption of the Merger Agreement, the approval of the Merger or any of the other
actions contemplated by the Merger Agreement. Stockholder shall immediately
cease and discontinue, and Stockholder shall ensure that Stockholder's
Representatives immediately cease and discontinue, any existing discussions with
any Person that relate to any Takeover Proposal. Nothing contained in this
Section 5 shall prevent any Representative of Stockholder, when acting solely in
his capacity as a director or officer of the Company, from causing the Company
to take the actions specified in the proviso to the first sentence of Section
4.16 of the Merger Agreement (to the extent all of the conditions set forth in
such proviso have been satisfied).
SECTION 6. REPRESENTATIONS AND WARRANTIES OF STOCKHOLDER.
Stockholder hereby represents and warrants to Parent as follows:
6.1 AUTHORIZATION, ETC. Stockholder has the absolute and unrestricted
right, power, authority and capacity to execute and deliver this Voting
Agreement and the Proxy and to perform Stockholder's obligations hereunder and
thereunder. The execution, delivery and performance of this Voting Agreement
and the Proxy have been duly authorized by all necessary action by Stockholder
and Stockholder's partners, and this Voting Agreement and the Proxy constitute
legal, valid and binding obligations of Stockholder, enforceable against
Stockholder in accordance with their terms, subject to (i) laws of general
application relating to bankruptcy, insolvency and the relief of debtors, and
(ii) rules of law governing specific performance, injunctive relief and other
equitable remedies.
6.2 NO CONFLICTS OR CONSENTS.
(a) The execution and delivery of this Voting Agreement and the Proxy
by Stockholder do not, and the performance of this Voting Agreement and the
Proxy by Stockholder will not: (i) conflict with or violate (A) any of the
provisions of Stockholder's partnership agreement, certificate of limited
partnership, bylaws or other charter or organizational documents, (B) any
resolution adopted by any advisory or other committee of Stockholder, or (C) any
law, rule, regulation, order, decree or judgment applicable to Stockholder or by
which Stockholder or any of Stockholder's properties is or may be bound or
affected; or (ii) result in or constitute (with or without notice or lapse of
time) any breach of or default under, or give to any other Person (with or
without notice or lapse of time) any right of termination, amendment,
acceleration or cancellation of, or result (with or without notice or lapse of
time) in the creation of any encumbrance or restriction on any of the Subject
Securities pursuant to, any contract to which Stockholder is a
4
<PAGE>
party or by which Stockholder or any of Stockholder's affiliates or properties
is or may be bound or affected (including any letter agreement between
Stockholder or Stockholder's general partner and any of Stockholder's limited
partners), except in the case of clause (i) or (ii) above where any of such
events would not have a material adverse effect on Stockholder or otherwise
impair Stockholder's ability to satisfy Stockholder's obligations hereunder.
(b) The execution and delivery of this Voting Agreement and the Proxy
by Stockholder do not, and the performance of this Voting Agreement and the
Proxy by Stockholder will not, require any consent or approval of any Person.
6.3 TITLE TO SECURITIES. As of the date of this Voting Agreement: (a)
Stockholder holds of record (free and clear of any encumbrances or restrictions)
the number of outstanding shares of Company Common Stock set forth under the
heading "Shares Held of Record" on the signature page hereof; (b) Stockholder
holds (free and clear of any encumbrances or restrictions) the options, warrants
and other rights to acquire shares of Company Common Stock set forth under the
heading "Options and Other Rights" on the signature page hereof; (c) Stockholder
Owns the additional securities of the Company set forth under the heading
"Additional Securities Beneficially Owned" on the signature page hereof; and (d)
Stockholder does not directly or indirectly Own any shares of capital stock or
other securities of the Company, or any option, warrant or other right to
acquire (by purchase, conversion or otherwise) any shares of capital stock or
other securities of the Company, other than the shares and options, warrants and
other rights specified on the signature page hereof.
6.4 ACCURACY OF REPRESENTATIONS. The representations and warranties
contained in this Voting Agreement are accurate in all material respects as of
the date of this Voting Agreement, will be accurate in all material respects at
all times through the Expiration Date and will be accurate in all material
respects as of the date of the consummation of the Merger as if made on that
date.
SECTION 7. ADDITIONAL COVENANTS OF STOCKHOLDER.
7.1 FURTHER ASSURANCES. From time to time and without additional
consideration, Stockholder shall (at Stockholder's sole expense) execute and
deliver, or cause to be executed and delivered, such additional transfers,
assignments, endorsements, proxies, consents and other instruments, and shall
(at Stockholder's sole expense) take such further actions, as Parent may
reasonably request for the purpose of carrying out and furthering the intent of
this Voting Agreement.
7.2 LEGEND. Immediately after the execution of this Voting Agreement (and
from time to time upon the acquisition by
5
<PAGE>
Stockholder of Ownership of any shares of Company Common Stock prior to the
Expiration Date), Stockholder shall ensure that each certificate evidencing any
outstanding shares of Company Common Stock or other securities of the Company
Owned by Stockholder and which are held in certificated form bears a legend in
the following form:
THE SECURITY OR SECURITIES REPRESENTED BY THIS CERTIFICATE MAY NOT BE SOLD,
EXCHANGED OR OTHERWISE TRANSFERRED OR DISPOSED OF EXCEPT IN COMPLIANCE WITH
THE PROVISIONS OF THE VOTING AGREEMENT DATED AS OF FEBRUARY 28, 1999,
BETWEEN GILEAD SCIENCES, INC. AND WARBURG, PINCUS INVESTORS, L.P., A COPY
OF WHICH IS ON FILE AT THE PRINCIPAL EXECUTIVE OFFICES OF GILEAD SCIENCES,
INC.
SECTION 8. MISCELLANEOUS.
8.1 SURVIVAL OF REPRESENTATIONS, WARRANTIES AND COVENANTS. All
representations, warranties, covenants and obligations of Stockholder contained
in this Voting Agreement shall survive the Expiration Date.
8.2 INDEMNIFICATION. Stockholder shall hold harmless and indemnify Parent
and Parent's affiliates from and against, and shall compensate and reimburse
Parent and Parent's affiliates for, any loss, damage, claim, liability, fee
(including attorneys' fees), demand, cost or expense (regardless of whether or
not such loss, damage, claim, liability, fee, demand, cost or expense relates to
a third-party claim) that is directly or indirectly suffered or incurred by
Parent or any of Parent's affiliates, or to which Parent or any of Parent's
affiliates otherwise becomes subject, and that arises directly or indirectly
from, or relates directly or indirectly to, (a) any inaccuracy in or breach of
any representation or warranty contained in this Voting Agreement, or (b) any
failure on the part of Stockholder to observe, perform or abide by, or any other
breach of, any restriction, covenant, obligation or other provision contained in
this Voting Agreement or in the Proxy.
8.3 INDEPENDENCE OF OBLIGATIONS. The covenants and obligations of
Stockholder set forth in this Voting Agreement shall be construed as independent
of any other agreement or arrangement between Stockholder, on the one hand, and
the Company or Parent, on the other. The existence of any claim or cause of
action by Stockholder against the Company or Parent shall not constitute a
defense to the enforcement of any of such covenants or obligations against
Stockholder.
8.4 SPECIFIC PERFORMANCE. Stockholder agrees that in the event of any
breach or threatened breach by Stockholder of any covenant, obligation or other
provision contained in this Voting Agreement, Parent shall be entitled (in
addition to any other remedy that may be available to Parent) to: (a) a decree
or order of specific performance or mandamus to enforce the
6
<PAGE>
observance and performance of such covenant, obligation or other provision; and
(b) an injunction restraining such breach or threatened breach. Stockholder
further agrees that neither Parent nor any other person or entity shall be
required to obtain, furnish or post any bond or similar instrument in connection
with or as a condition to obtaining any remedy referred to in this Section 8.4,
and Stockholder irrevocably waives any right Stockholder may have to require the
obtaining, furnishing or posting of any such bond or similar instrument.
8.5 OTHER AGREEMENTS. Nothing in this Voting Agreement shall limit any of
the rights or remedies of Parent under the Merger Agreement, or any of the
rights or remedies of Parent or any of the obligations of Stockholder under any
agreement between Stockholder and Parent or any certificate or instrument
executed on behalf of Stockholder in favor of Parent; and nothing in the Merger
Agreement or in any other agreement, certificate or instrument shall limit any
of the rights or remedies of Parent or any of the obligations of Stockholder
under this Voting Agreement.
8.6 NOTICES. Any notice or other communication required or permitted to
be delivered to Stockholder or Parent under this Voting Agreement shall be in
writing and shall be deemed properly delivered, given and received when
delivered to the address or facsimile telephone number set forth beneath the
name of such party below (or to such other address or facsimile telephone number
as such party shall have specified in a written notice given to the other
party):
IF TO PARENT:
Gilead Sciences, Inc
333 Lakeside Drive
Foster City, CA 94404
Attn: General Counsel
Fax: (650) 522-5622
IF TO STOCKHOLDER:
Warburg, Pincus Investors, L.P.
466 Lexington Ave.
New York, NY 10017
Attn: Scott Arenase, Esq.
Fax: (212) 878-9200
8.7 SEVERABILITY. If any provision of this Voting Agreement or any part
of any such provision is held under any circumstances to be invalid or
unenforceable in any jurisdiction, then (a) such provision or part thereof
shall, with respect to such circumstances and in such jurisdiction, be deemed
amended to conform to applicable laws so as to be valid and enforceable to the
fullest possible extent, (b) the invalidity or unenforceability of such
provision or part thereof under such
7
<PAGE>
circumstances and in such jurisdiction shall not affect the validity or
enforceability of such provision or part thereof under any other circumstances
or in any other jurisdiction, and (c) the invalidity or unenforceability of such
provision or part thereof shall not affect the validity or enforceability of the
remainder of such provision or the validity or enforceability of any other
provision of this Voting Agreement. Each provision of this Voting Agreement is
separable from every other provision of this Voting Agreement, and each part of
each provision of this Voting Agreement is separable from every other part of
such provision.
8.8 APPLICABLE LAW; JURISDICTION. THIS VOTING AGREEMENT IS MADE UNDER,
AND SHALL BE CONSTRUED AND ENFORCED IN ACCORDANCE WITH, THE LAWS OF DELAWARE
APPLICABLE TO AGREEMENTS MADE AND TO BE PERFORMED SOLELY THEREIN, WITHOUT GIVING
EFFECT TO PRINCIPLES OF CONFLICTS OF LAW. In any action between the parties
hereto, whether arising out of this Voting Agreement or otherwise: (a) each of
the parties irrevocably and unconditionally consents and submits to the
exclusive jurisdiction and venue of the state and federal courts located in the
State of Delaware; (b) if any such action is commenced in a state court, then,
subject to applicable law, no party shall object to the removal of such action
to any federal court located in the State of Delaware; (c) each of the parties
irrevocably waives the right to trial by jury; and (d) each of the parties
irrevocably consents to service of process by first class certified mail, return
receipt requested, postage prepaid, to the address at which such party is to
receive notice in accordance with Section 8.6.
8.9 WAIVER. No failure on the part of Parent to exercise any power,
right, privilege or remedy under this Voting Agreement, and no delay on the part
of Parent in exercising any power, right, privilege or remedy under this Voting
Agreement, shall operate as a waiver of such power, right, privilege or remedy;
and no single or partial exercise of any such power, right, privilege or remedy
shall preclude any other or further exercise thereof or of any other power,
right, privilege or remedy. Parent shall not be deemed to have waived any claim
arising out of this Voting Agreement, or any power, right, privilege or remedy
under this Voting Agreement, unless the waiver of such claim, power, right,
privilege or remedy is expressly set forth in a written instrument duly executed
and delivered on behalf of Parent; and any such waiver shall not be applicable
or have any effect except in the specific instance in which it is given.
8.10 ATTORNEYS' FEES. If any legal action or other legal proceeding
relating to this Voting Agreement or the enforcement of any provision of this
Voting Agreement is brought against Stockholder, the prevailing party shall be
entitled to recover reasonable attorneys' fees, costs and disbursements (in
addition to any other relief to which the prevailing party may be entitled).
8
<PAGE>
8.11 CAPTIONS. The captions contained in this Voting Agreement are for
convenience of reference only, shall not be deemed to be a part of this Voting
Agreement and shall not be referred to in connection with the construction or
interpretation of this Voting Agreement.
8.12 FURTHER ASSURANCES. Stockholder shall execute and/or cause to be
delivered to Parent such instruments and other documents and shall take such
other actions as Parent may reasonably request to effectuate the intent and
purposes of this Voting Agreement.
8.13 ENTIRE AGREEMENT. This Voting Agreement and any Affiliate Agreement
or Registration Rights Agreement between Stockholder and Parent collectively set
forth the entire understanding of Parent and Stockholder relating to the subject
matter hereof and thereof and supersede all other prior agreements and
understandings between Parent and Stockholder relating to the subject matter
hereof and thereof.
8.14 NON-EXCLUSIVITY. The rights and remedies of Parent under this Voting
Agreement are not exclusive of or limited by any other rights or remedies which
it may have, whether at law, in equity, by contract or otherwise, all of which
shall be cumulative (and not alternative). Without limiting the generality of
the foregoing, the rights and remedies of Parent under this Voting Agreement,
and the obligations and liabilities of Stockholder under this Voting Agreement,
are in addition to their respective rights, remedies, obligations and
liabilities under common law requirements and under all applicable statutes,
rules and regulations. Nothing in this Voting Agreement shall limit any of
Stockholder's obligations, or the rights or remedies of Parent, under any
Affiliate Agreement between Parent and Stockholder; and nothing in any such
Affiliate Agreement shall limit any of Stockholder's obligations, or any of the
rights or remedies of Parent, under this Voting Agreement.
8.15 AMENDMENTS. This Voting Agreement may not be amended, modified,
altered or supplemented other than by means of a written instrument duly
executed and delivered on behalf of Parent and Stockholder.
8.16 ASSIGNMENT; BINDING EFFECT. Neither this Voting Agreement nor any of
the interests or obligations hereunder may be assigned or delegated by
Stockholder, and any attempted or purported assignment or delegation of any of
such interests or obligations shall be void. Subject to the preceding sentence,
this Voting Agreement shall be binding upon Stockholder and Stockholder's
representatives, successors and assigns, and shall inure to the benefit of
Parent and its successors and assigns. Without limiting any of the restrictions
set forth in Section 2 or elsewhere in this Voting Agreement, this Voting
Agreement shall be binding upon any Person to whom any Subject Securities are
Transferred prior to the termination of this Agreement.
9
<PAGE>
Nothing in this Voting Agreement is intended to confer on any Person (other than
Parent and its successors and assigns) any rights or remedies of any nature.
8.17 EXPENSES. All costs and expenses incurred in connection with the
transactions contemplated by this Voting Agreement shall be paid by the party
incurring such costs and expenses.
8.18 TERMINATION.
(a) This Voting Agreement shall automatically terminate on the
Expiration Date; PROVIDED, HOWEVER, that the termination of this Voting
Agreement shall not relieve Stockholder from any liability for any previous
breach of this Voting Agreement.
(b) If the Parent Share Value (as defined in the Merger Agreement) is
less than the Specified Price (as defined below), then, immediately prior to the
Special Meeting (as defined in the Merger Agreement), (i) Stockholder shall be
entitled to revoke the Proxy, and (ii) Stockholder's obligations under Sections
3.1 and 3.2(a)(ii) shall terminate; PROVIDED, HOWEVER, that (1) the termination
of such obligations shall not relieve Stockholder from any liability for any
previous breach of any of such obligations, and (2) Stockholder's obligations
under Sections 5 and 8 shall remain in full force and effect until this Voting
Agreement is otherwise terminated pursuant to Section 8.18(a). The Specified
Price shall be $27.00; PROVIDED, HOWEVER, that in the event the outstanding
Parent Shares (as defined in the Merger Agreement shall be changed into a
different number of shares by reason of any stock dividend, subdivision,
reclassification, split-up, combination or the like, the Specified Price shall
be appropriately adjusted.
8.19 COUNTERPARTS. This Voting Agreement may be executed by the parties in
separate counterparts, each of which when so executed and delivered shall be an
original, but all of which shall together constitute one and the same
instrument.
8.20 CONSTRUCTION.
(a) For purposes of this Voting Agreement, whenever the context
requires: the singular number shall include the plural, and vice versa; the
masculine gender shall include the feminine and neuter genders; the feminine
gender shall include the masculine and neuter genders; and the neuter gender
shall include masculine and feminine genders.
(b) The parties agree that any rule of construction to the effect
that ambiguities are to be resolved against the drafting party shall not be
applied in the construction or interpretation of this Voting Agreement.
10
<PAGE>
(c) As used in this Voting Agreement, the words "include" and
"including," and variations thereof, shall not be deemed to be terms of
limitation, but rather shall be deemed to be followed by the words "without
limitation."
(d) Except as otherwise indicated, all references in this Voting
Agreement to "Sections" and "Exhibits" are intended to refer to Sections of this
Voting Agreement and Exhibits to this Voting Agreement.
11
<PAGE>
IN WITNESS WHEREOF, Parent and Stockholder have caused this Voting
Agreement to be executed as of the date first written above.
GILEAD SCIENCES, INC.
By: /s/ Mark L. Perry
-------------------------------
WARBURG, PINCUS INVESTORS, L.P.
By: Warburg, Pincus & Co.,
General Partner
By: /s/ James E. Thomas
-------------------------------
Partner
SHARES HELD ADDITIONAL SECURITIES
OF RECORD OPTIONS AND OTHER RIGHTS BENEFICIALLY OWNED
- ------------ ------------------------ ---------------------
4,287,755 0 WARRANT FOR 125,000 SHARES AT
$12.50 PER SHARE
<PAGE>
EXHIBIT A
FORM OF IRREVOCABLE PROXY
The undersigned stockholder of NeXstar Pharmaceuticals, Inc., a Delaware
corporation (the "Company"), hereby irrevocably (to the fullest extent permitted
by law) appoints and constitutes John C. Martin, Mark L. Perry and Gilead
Sciences, Inc., a Delaware corporation ("Parent"), and each of them, the
attorneys and proxies of the undersigned with full power of substitution and
resubstitution, to the full extent of the undersigned's rights with respect to
(i) the outstanding shares of capital stock of the Company owned of record by
the undersigned as of the date of this proxy, which shares are specified on the
final page of this proxy, and (ii) any and all other shares of capital stock of
the Company which the undersigned may acquire on or after the date hereof. (The
shares of the capital stock of the Company referred to in clauses "(i)" and
"(ii)" of the immediately preceding sentence are collectively referred to as the
"Shares.") Upon the execution hereof, all prior proxies given by the
undersigned with respect to any of the Shares are hereby revoked, and the
undersigned agrees that no subsequent proxies will be given with respect to any
of the Shares.
This proxy is irrevocable, is coupled with an interest, is granted in
connection with the execution and delivery of the Voting Agreement, dated as of
the date hereof, between Parent and the undersigned (the "Voting Agreement") and
is granted in consideration of Parent entering into the Agreement and Plan of
Merger, dated as of the date hereof, among Parent, Gazelle Acquisition Sub, Inc.
and the Company (the "Merger Agreement"); PROVIDED, HOWEVER, that the
undersigned may revoke this proxy under the circumstances specified in Section
8.18(b) of the Voting Agreement.
The attorneys and proxies named above (and their successors) will be
empowered, and may exercise this proxy, to vote the Shares at any meeting of the
stockholders of the Company, however called, or in connection with any
solicitation of written consents from stockholders of the Company, in favor of
the approval and adoption of the Merger Agreement and the approval of the merger
contemplated thereby, and in favor of each of the other actions contemplated by
the Merger Agreement. The undersigned may vote the Shares on all other matters.
This proxy shall be binding upon the representatives, successors and
assigns of the undersigned (including any transferee of any of the Shares).
If any provision of this proxy or any part of any such provision is held under
any circumstances to be invalid or unenforceable in any jurisdiction, then (a)
such provision or part thereof shall, with respect to such circumstances and in
such jurisdiction, be deemed amended to conform to applicable laws so as to be
valid and enforceable to the fullest possible extent, (b) the invalidity or
unenforceability of such provision or part thereof under such circumstances and
in such jurisdiction shall not affect the validity or enforceability of such
provision or part thereof under any other circumstances or in any other
jurisdiction, and (c) the invalidity or unenforceability of such provision or
part thereof shall not affect the
<PAGE>
validity or enforceability of the remainder of such provision or the validity or
enforceability of any other provision of this proxy. Each provision of this
proxy is separable from every other provision of this proxy, and each part of
each provision of this proxy is separable from every other part of such
provision.
This proxy shall terminate upon the valid termination of the Voting
Agreement.
Dated: February 28, 1999
Warburg, Pincus Investors, L.P.
By: Warburg, Pincus & Co., General Partner
By: /s/ James E. Thomas
---------------------------
Partner
Number of shares of common stock of the
Company owned of record as of the date of
this proxy:
4,287,755
------------------------------
<PAGE>
VOTING AGREEMENT
THIS VOTING AGREEMENT is entered into as of February 28, 1999, by and among
GILEAD SCIENCES, INC., a Delaware corporation ("Parent"), and WARBURG, PINCUS
CAPITAL PARTNERS LIQUIDATING TRUST (the "Trust").
RECITALS
A. Parent, Gazelle Acquisition Sub, Inc., a Delaware corporation and a
wholly owned subsidiary of Parent ("Merger Sub"), and NeXstar Pharmaceuticals,
Inc., a Delaware corporation (the "Company"), are entering into an Agreement and
Plan of Merger of even date herewith (the "Merger Agreement") which provides
(subject to the conditions set forth therein) for the merger of Merger Sub into
the Company (the "Merger").
B. In order to induce Parent and Merger Sub to enter into the Merger
Agreement, the Trust and the Trustees are entering into this Voting Agreement on
behalf of the Trust.
AGREEMENT
The parties to this Voting Agreement, intending to be legally bound, agree
as follows:
SECTION 1. CERTAIN DEFINITIONS.
For purposes of this Voting Agreement:
(a) "COMPANY COMMON STOCK" shall mean the common stock, par value
$.01 per share, of the Company.
(b) "EXPIRATION DATE" shall mean the earlier of (i) the date upon
which the Merger Agreement is validly terminated, or (ii) the date upon which
the Merger becomes effective.
(c) The Trustees shall be deemed to "OWN" or to have acquired
"OWNERSHIP" of a security if any of the Trustees or the Trust: (i) is the record
owner of such security; or (ii) is the "beneficial owner" (within the meaning of
Rule 13d-3 under the Securities Exchange Act of 1934) of such security.
(d) "PERSON" shall mean any (i) individual, (ii) corporation, limited
liability company, partnership, trust or other entity, or (iii) governmental
authority.
(e) "SUBJECT SECURITIES" shall mean: (i) all securities of the
Company (including all shares of Company Common
<PAGE>
Stock and all options, warrants and other rights to acquire shares of Company
Common Stock) Owned by the Trust as of the date of this Voting Agreement; and
(ii) all additional securities of the Company (including all additional shares
of Company Common Stock and all additional options, warrants and other rights to
acquire shares of Company Common Stock) of which the Trust acquires Ownership
during the period from the date of this Voting Agreement through the Expiration
Date.
(f) A Person shall be deemed to have a effected a "TRANSFER" of a
security if such Person directly or indirectly: (i) sells, pledges, encumbers,
grants an option with respect to, transfers, distributes or disposes of such
security or any interest in such security; or (ii) enters into an agreement or
commitment contemplating the possible sale of, pledge of, encumbrance of, grant
of an option with respect to, transfer of or disposition of such security or any
interest therein.
SECTION 2. TRANSFER OF SUBJECT SECURITIES.
2.1 TRANSFEREE OF SUBJECT SECURITIES TO BE BOUND BY THIS VOTING AGREEMENT.
During the period from the date of this Voting Agreement through the Expiration
Date, the Trust shall not cause or permit any Transfer of any of the Subject
Securities to be effected (whether to the beneficiaries of the Trust or to any
other Person or Persons) unless each Person to which any of such Subject
Securities, or any interest in any of such Subject Securities, is or may be
Transferred shall have: (a) executed a counterpart of this Voting Agreement and
a proxy in the form attached hereto as Exhibit A (with such modifications as
Parent may reasonably request); and (b) agreed to hold such Subject Securities
(or interest in such Subject Securities) subject to all of the terms and
provisions of this Voting Agreement.
2.2 NO TRANSFER OF VOTING RIGHTS. The Trust shall ensure that, during the
period from the date of this Voting Agreement through the Expiration Date: (a)
none of the Subject Securities is deposited into a voting trust; and (b) no
proxy is granted, and no voting agreement or similar agreement is entered into,
with respect to any of the Subject Securities.
SECTION 3. VOTING OF SHARES.
3.1 VOTING AGREEMENT. During the period from the date of this Voting
Agreement through the Expiration Date:
(a) at any meeting of stockholders of the Company, however called,
the Trust shall (unless otherwise directed in writing by Parent) cause all
outstanding shares of Company Common Stock that are Owned by the Trust as
of the record date fixed for such meeting to be voted in favor of the
approval and adoption of the Merger Agreement and the
2
<PAGE>
approval of the Merger, and in favor of each of the other actions
contemplated by the Merger Agreement; and
(b) in the event written consents are solicited or otherwise sought
from stockholders of the Company with respect to the approval or adoption
of the Merger Agreement, with respect to the approval of the Merger or with
respect to any of the other actions contemplated by the Merger Agreement,
the Trust shall (unless otherwise directed in writing by Parent) cause to
be validly executed, with respect to all outstanding shares of Company
Common Stock that are Owned by the Trust as of the record date fixed for
the consent to the proposed action, a written consent or written consents
to such proposed action.
3.2 PROXY; FURTHER ASSURANCES.
(a) Contemporaneously with the execution of this Voting Agreement:
(i) the Trust shall deliver to Parent a proxy in the form attached to this
Voting Agreement as Exhibit A, which shall be irrevocable to the fullest extent
permitted by law, with respect to the shares referred to therein (the "Proxy");
and (ii) the Trust shall cause to be delivered to Parent an additional proxy (in
the form attached hereto as Exhibit A) executed on behalf of the record owner of
any outstanding shares of Company Common Stock that are owned beneficially
(within the meaning of Rule 13d-3 under the Securities Exchange Act of 1934),
but not of record, by the Trust.
(b) The Trust shall, at the expense of the Trust, perform such
further acts and execute such further documents and instruments as may
reasonably be required to vest in Parent the power to carry out and give effect
to the provisions of this Voting Agreement.
SECTION 4. WAIVER OF APPRAISAL RIGHTS.
The Trust hereby irrevocably and unconditionally waives, and agrees to
cause to be waived and to prevent the exercise of, any rights of appraisal, any
dissenters' rights and any similar rights relating to the Merger or any related
transaction that the Trust or any other Person may have by virtue of the
ownership of any Subject Securities.
SECTION 5. NO SOLICITATION.
During the period from the date of this Voting Agreement through the
Expiration Date, the Trust shall not, nor shall it authorize or permit any
Representative or beneficiary of the Trust to, directly or indirectly: (i)
solicit, initiate or encourage the submission or announcement of any Takeover
Proposal (as defined in the Merger Agreement); (ii) participate in any
discussions or negotiations regarding, or furnish to any Person
3
<PAGE>
any information with respect or in response to, or take any other action to
facilitate any inquiries or the making of any proposal that constitutes, or may
reasonably be expected to lead to, any Takeover Proposal; or (iii) induce or
encourage any other stockholder of the Company to vote against, or to fail to
vote in favor of, the approval and adoption of the Merger Agreement, the
approval of the Merger or any of the other Transactions contemplated by the
Merger Agreement. The Trust shall immediately cease and discontinue, and the
Trust shall ensure that any Representative of the Trust immediately cease and
discontinue, any existing discussions with any Person that relate to any
Takeover Proposal. Nothing contained in this Section 5 shall prevent any
Representative of the Trust, when acting solely in his capacity as a director or
officer of the Company, from causing the Company to take the actions specified
in the proviso to the first sentence of Section 4.16 of the Merger Agreement (to
the extent all of the conditions set forth in such proviso have been satisfied).
SECTION 6. REPRESENTATIONS AND WARRANTIES OF THE TRUSTEES.
The Trust hereby represents and warrants to Parent as follows:
6.1 AUTHORIZATION, ETC. There are no trustees of the Trust other than
Lionel I. Pincus, John L. Vogelstein and Stephen Distler. The Trustee executing
this Voting Agreement on behalf of the Trust has all necessary power and
authority, under the trust agreement for the Trust and otherwise, to by the
Trust by his sole signature and to cause the Trust to enter into this Voting
Agreement and to perform its obligations hereunder, and no action or consent on
the part of either of the other Trustees of the Trust, any of the beneficiaries
of the Trust or any other Person is necessary to permit the Trust to enter into
this Voting Agreement or to perform its obligations hereunder. This Voting
Agreement and the Proxy constitute legal, valid and binding obligations of the
Trust enforceable against the Trust in accordance with their terms, subject to
(i) laws of general application relating to bankruptcy, insolvency and the
relief of debtors, and (ii) rules of law governing specific performance,
injunctive relief and other equitable remedies.
6.2 NO CONFLICTS OR CONSENTS.
(a) The execution and delivery of this Voting Agreement and the Proxy
by the Trust do not, and the performance of this Voting Agreement and the Proxy
by the Trust will not: (i) conflict with or violate (A) any agreement or other
instrument to which the Trust is a party or by which the Trust or any of the
Subject Securities is bound or (B) any law, rule, regulation, order, decree or
judgment applicable to the Trust or by which the Trust or any of the Trust's
properties is or may be bound or affected; or (ii) result in or constitute (with
or without notice or lapse of time) any breach of or default under, or give to
any other Person (with or without notice
4
<PAGE>
or lapse of time) any right of termination, amendment, acceleration or
cancellation of, or result (with or without notice or lapse of time) in the
creation of any encumbrance or restriction on any of the Subject Securities
pursuant to, the Trust Agreement for the Trust or any contract to which the
Trust is a party or by which the Trust or any of the Trust's affiliates or
properties is or may be bound or affected, except in the case of clause (i) or
(ii) above where any of such events would not have a material adverse effect on
the Trust or otherwise impair the Trust's ability to satisfy its obligations
hereunder.
(b) The execution and delivery of this Voting Agreement and the Proxy
by the Trust does not, and the performance of this Voting Agreement and the
Proxy by the Trust will not, require any consent or approval of any Person.
6.3 TITLE TO SECURITIES. As of the date of this Voting Agreement: (a)
the Trust holds of record (free and clear of any encumbrances or restrictions)
the number of outstanding shares of Company Common Stock set forth under the
heading "Shares Held of Record" on the signature page hereof; (b) the Trust
holds (free and clear of any encumbrances or restrictions) the options, warrants
and other rights to acquire shares of Company Common Stock set forth under the
heading "Options and Other Rights" on the signature page hereof; (c) the Trust
Owns the additional securities of the Company set forth under the heading
"Additional Securities Beneficially Owned" on the signature page hereof; and (d)
the Trust does not directly or indirectly Own any shares of capital stock or
other securities of the Company, or any option, warrant or other right to
acquire (by purchase, conversion or otherwise) any shares of capital stock or
other securities of the Company, other than the shares and options, warrants and
other rights specified on the signature page hereof.
6.4 ACCURACY OF REPRESENTATIONS. The representations and warranties
contained in this Voting Agreement are accurate in all material respects as of
the date of this Voting Agreement, will be accurate in all material respects at
all times through the Expiration Date and will be accurate in all material
respects as of the date of the consummation of the Merger as if made on that
date.
SECTION 7. ADDITIONAL COVENANTS OF THE TRUSTEES.
7.1 FURTHER ASSURANCES. From time to time and without additional
consideration, the Trust shall (at the expense of the Trust) execute and
deliver, or cause to be executed and delivered, such additional transfers,
assignments, endorsements, proxies, consents and other instruments, and shall
(at the expense of the Trust) take such further actions, as Parent may
5
<PAGE>
reasonably request for the purpose of carrying out and furthering the intent of
this Voting Agreement.
7.2 LEGEND. Immediately after the execution of this Voting Agreement (and
from time to time upon the acquisition by the Trust of Ownership of any shares
of Company Common Stock prior to the Expiration Date), the Trust shall ensure
that each certificate evidencing any outstanding shares of Company Common Stock
or other securities of the Company Owned by the Trust and which are in
certificated form bears a legend in the following form:
THE SECURITY OR SECURITIES REPRESENTED BY THIS CERTIFICATE MAY NOT BE SOLD,
EXCHANGED OR OTHERWISE TRANSFERRED OR DISPOSED OF EXCEPT IN COMPLIANCE WITH
THE PROVISIONS OF THE VOTING AGREEMENT DATED AS OF FEBRUARY 28, 1999, AMONG
GILEAD SCIENCES, INC., AND THE WARBURG, PINCUS CAPITAL PARTNERS LIQUIDATING
TRUST, A COPY OF WHICH IS ON FILE AT THE PRINCIPAL EXECUTIVE OFFICES OF
GILEAD SCIENCES, INC.
SECTION 8. MISCELLANEOUS.
8.1 SURVIVAL OF REPRESENTATIONS, WARRANTIES AND COVENANTS. All
representations, warranties, covenants and obligations of the Trust contained in
this Voting Agreement shall survive the Expiration Date.
8.2 INDEMNIFICATION. The Trust shall hold harmless and indemnify Parent
and Parent's affiliates from and against, and shall compensate and reimburse
Parent and Parent's affiliates for, any loss, damage, claim, liability, fee
(including attorneys' fees), demand, cost or expense (regardless of whether or
not such loss, damage, claim, liability, fee, demand, cost or expense relates to
a third-party claim) that is directly or indirectly suffered or incurred by
Parent or any of Parent's affiliates, or to which Parent or any of Parent's
affiliates otherwise becomes subject, and that arises directly or indirectly
from, or relates directly or indirectly to, (a) any inaccuracy in or breach of
any representation or warranty contained in this Voting Agreement, or (b) any
failure on the part of any of the Trust to observe, perform or abide by, or any
other breach of, any restriction, covenant, obligation or other provision
contained in this Voting Agreement or in the Proxy.
8.3 INDEPENDENCE OF OBLIGATIONS. The covenants and obligations of the
Trust set forth in this Voting Agreement shall be construed as independent of
any other agreement or arrangement between the Trust, on the one hand, and the
Company or Parent, on the other. The existence of any claim or cause of action
by the Trust or the Trustees against the Company or Parent shall not constitute
a defense to the enforcement of any of such covenants or obligations against the
Trust.
6
<PAGE>
8.4 SPECIFIC PERFORMANCE. The Trust agrees that in the event of any
breach or threatened breach by the Trust of any covenant, obligation or other
provision contained in this Voting Agreement, Parent shall be entitled (in
addition to any other remedy that may be available to Parent) to: (a) a decree
or order of specific performance or mandamus to enforce the observance and
performance of such covenant, obligation or other provision; and (b) an
injunction restraining such breach or threatened breach. The Trust further
agrees that neither Parent nor any other person or entity shall be required to
obtain, furnish or post any bond or similar instrument in connection with or as
a condition to obtaining any remedy referred to in this Section 8.4, and the
Trust irrevocably waives any right the Trust may have to require the obtaining,
furnishing or posting of any such bond or similar instrument.
8.5 OTHER AGREEMENTS. Nothing in this Voting Agreement shall limit any of
the rights or remedies of Parent under the Merger Agreement, or any of the
rights or remedies of Parent or any of the obligations of the Trust under any
agreement between the Trust and Parent or any certificate or instrument executed
on behalf of the Trust in favor of Parent; and nothing in the Merger Agreement
or in any other agreement, certificate or instrument shall limit any of the
rights or remedies of Parent or any of the obligations of the Trust under this
Voting Agreement.
8.6 NOTICES. Any notice or other communication required or permitted to
be delivered to the Trust or Parent under this Voting Agreement shall be in
writing and shall be deemed properly delivered, given and received when
delivered to the address or facsimile telephone number set forth beneath the
name of such party below (or to such other address or facsimile telephone number
as such party shall have specified in a written notice given to the other
party):
IF TO PARENT:
Gilead Sciences, Inc
333 Lakeside Drive
Foster City, CA 94404
Attn: General Counsel
Fax: (650) 522-5622
IF TO THE TRUST OR THE TRUSTEES:
Warburg, Pincus Capital Partners Liquidating Trust
466 Lexington Avenue
New York NY 10017
Attn: Stephen Distler, Trustee
Fax: (212) 878-9200
8.7 SEVERABILITY. If any provision of this Voting Agreement or any part
of any such provision is held under any
7
<PAGE>
circumstances to be invalid or unenforceable in any jurisdiction, then (a) such
provision or part thereof shall, with respect to such circumstances and in such
jurisdiction, be deemed amended to conform to applicable laws so as to be valid
and enforceable to the fullest possible extent, (b) the invalidity or
unenforceability of such provision or part thereof under such circumstances and
in such jurisdiction shall not affect the validity or enforceability of such
provision or part thereof under any other circumstances or in any other
jurisdiction, and (c) the invalidity or unenforceability of such provision or
part thereof shall not affect the validity or enforceability of the remainder of
such provision or the validity or enforceability of any other provision of this
Voting Agreement. Each provision of this Voting Agreement is separable from
every other provision of this Voting Agreement, and each part of each provision
of this Voting Agreement is separable from every other part of such provision.
8.8 APPLICABLE LAW; JURISDICTION. THIS VOTING AGREEMENT IS MADE UNDER,
AND SHALL BE CONSTRUED AND ENFORCED IN ACCORDANCE WITH, THE LAWS OF DELAWARE
APPLICABLE TO AGREEMENTS MADE AND TO BE PERFORMED SOLELY THEREIN, WITHOUT GIVING
EFFECT TO PRINCIPLES OF CONFLICTS OF LAW. In any action between the parties
hereto, whether arising out of this Voting Agreement or otherwise: (a) each of
the parties irrevocably and unconditionally consents and submits to the
exclusive jurisdiction and venue of the state and federal courts located in the
State of Delaware; (b) if any such action is commenced in a state court, then,
subject to applicable law, no party shall object to the removal of such action
to any federal court located in the State of Delaware; (c) each of the parties
irrevocably waives the right to trial by jury; and (d) each of the parties
irrevocably consents to service of process by first class certified mail, return
receipt requested, postage prepaid, to the address at which such party is to
receive notice in accordance with Section 8.6.
8.9 WAIVER. No failure on the part of Parent to exercise any power,
right, privilege or remedy under this Voting Agreement, and no delay on the part
of Parent in exercising any power, right, privilege or remedy under this Voting
Agreement, shall operate as a waiver of such power, right, privilege or remedy;
and no single or partial exercise of any such power, right, privilege or remedy
shall preclude any other or further exercise thereof or of any other power,
right, privilege or remedy. Parent shall not be deemed to have waived any claim
arising out of this Voting Agreement, or any power, right, privilege or remedy
under this Voting Agreement, unless the waiver of such claim, power, right,
privilege or remedy is expressly set forth in a written instrument duly executed
and delivered on behalf of Parent; and any such waiver shall not be applicable
or have any effect except in the specific instance in which it is given.
8
<PAGE>
8.10 ATTORNEYS' FEES. If any legal action or other legal proceeding
relating to this Voting Agreement or the enforcement of any provision of this
Voting Agreement is brought against the Trust or the Trustees (or any of them),
the prevailing party shall be entitled to recover reasonable attorneys' fees,
costs and disbursements (in addition to any other relief to which the prevailing
party may be entitled).
8.11 CAPTIONS. The captions contained in this Voting Agreement are for
convenience of reference only, shall not be deemed to be a part of this Voting
Agreement and shall not be referred to in connection with the construction or
interpretation of this Voting Agreement.
8.12 FURTHER ASSURANCES. The Trust shall execute and/or cause to be
delivered to Parent such instruments and other documents and shall take such
other actions as Parent may reasonably request to effectuate the intent and
purposes of this Voting Agreement.
8.13 ENTIRE AGREEMENT. This Voting Agreement and any Affilate Agreement or
Registration Rights Agreement between the Trust and Parent collectively set
forth the entire understanding of Parent and the Trust relating to the subject
matter hereof and thereof and supersede all other prior agreements and
understandings between Parent and the Trust relating to the subject matter
hereof and thereof.
8.14 NON-EXCLUSIVITY. The rights and remedies of Parent under this Voting
Agreement are not exclusive of or limited by any other rights or remedies which
it may have, whether at law, in equity, by contract or otherwise, all of which
shall be cumulative (and not alternative). Without limiting the generality of
the foregoing, the rights and remedies of Parent under this Voting Agreement,
and the obligations and liabilities of the Trust under this Voting Agreement,
are in addition to their respective rights, remedies, obligations and
liabilities under common law requirements and under all applicable statutes,
rules and regulations. Nothing in this Voting Agreement shall limit any of the
obligations of the Trust or the rights or remedies of Parent, under any
Affiliate Agreement between Parent and the Trust; and nothing in any such
Affiliate Agreement shall limit any of the obligations of the Trust, or any of
the rights or remedies of Parent, under this Voting Agreement.
8.15 AMENDMENTS. This Voting Agreement may not be amended, modified,
altered or supplemented other than by means of a written instrument duly
executed and delivered on behalf of Parent and the Trust.
8.16 ASSIGNMENT; BINDING EFFECT. Neither this Voting Agreement nor any of
the interests or obligations hereunder may be assigned or delegated by the Trust
and any attempted or purported assignment or delegation of any of such interests
or
9
<PAGE>
obligations shall be void. Subject to the preceding sentence, this Voting
Agreement shall be binding upon the Trust, its Representatives, and their
respective successors and assigns, and shall inure to the benefit of Parent and
its successors and assigns. Without limiting any of the restrictions set forth
in Section 2 or elsewhere in this Voting Agreement, this Voting Agreement shall
be binding upon any Person to whom any Subject Securities are Transferred prior
to the termination of this Agreement. Nothing in this Voting Agreement is
intended to confer on any Person (other than Parent and its successors and
assigns) any rights or remedies of any nature.
8.17 EXPENSES. All costs and expenses incurred in connection with the
transactions contemplated by this Voting Agreement shall be paid by the party
incurring such costs and expenses.
8.18 TERMINATION.
(a) This Voting Agreement shall automatically terminate on the
Expiration Date; PROVIDED, HOWEVER, that the termination of this Voting
Agreement shall not relieve the Trust from any liability for any previous breach
of this Voting Agreement.
(b) If the Parent Share Value (as defined in the Merger Agreement) is
less than the Specified Price (as defined below), then, immediately prior to the
Special Meeting (as defined in the Merger Agreement), (i) the Trust shall be
entitled to revoke the Proxy, and (ii) the obligations of the Trust under
Sections 3.1 and 3.2(a)(ii) shall terminate; PROVIDED, HOWEVER, that (1) the
termination of such obligations shall not relieve the Trust from any liability
for any previous breach of any of such obligations, and (2) the obligations of
the Trust under Sections 5 and 8 shall remain in full force and effect until
this Voting Agreement is otherwise terminated pursuant to Section 8.18(a). The
Specified Price shall be $27.00; PROVIDED, HOWEVER, that in the event the
outstanding Parent Shares (as defined in the Merger Agreement) shall be changed
into a different number of shares by reason of any stock dividend, subdivision,
reclassification, split-up, combination or the like, the Specified Price shall
be appropriately adjusted.
8.19 COUNTERPARTS. This Voting Agreement may be executed by the parties in
separate counterparts, each of which when so executed and delivered shall be an
original, but all of which shall together constitute one and the same
instrument.
8.20 CONSTRUCTION.
(a) For purposes of this Voting Agreement, whenever the context
requires: the singular number shall include the
10
<PAGE>
plural, and vice versa; the masculine gender shall include the feminine and
neuter genders; the feminine gender shall include the masculine and neuter
genders; and the neuter gender shall include masculine and feminine genders.
(b) The parties agree that any rule of construction to the effect
that ambiguities are to be resolved against the drafting party shall not be
applied in the construction or interpretation of this Voting Agreement.
(c) As used in this Voting Agreement, the words "include" and
"including," and variations thereof, shall not be deemed to be terms of
limitation, but rather shall be deemed to be followed by the words "without
limitation."
(d) Except as otherwise indicated, all references in this Voting
Agreement to "Sections" and "Exhibits" are intended to refer to Sections of this
Voting Agreement and Exhibits to this Voting Agreement.
11
<PAGE>
IN WITNESS WHEREOF, Parent and the Trustees on behalf of the Trust have
caused this Voting Agreement to be executed as of the date first written above.
GILEAD SCIENCES, INC.
By: /s/ Mark L. Perry
-----------------------------
WARBURG, PINCUS CAPITAL PARTNERS
LIQUIDATING TRUST
By: /s/ Stephen Distler
-----------------------------
Stephen Distler, Trustee
SHARES HELD ADDITIONAL SECURITIES
OF RECORD OPTIONS AND OTHER RIGHTS BENEFICIALLY OWNED
- ----------- ------------------------ ---------------------
3,600,792 0
<PAGE>
EXHIBIT A
FORM OF IRREVOCABLE PROXY
The undersigned stockholder of NeXstar Pharmaceuticals, Inc., a Delaware
corporation (the "Company"), hereby irrevocably (to the fullest extent permitted
by law) appoints and constitutes John C. Martin, Mark L. Perry and Gilead
Sciences, Inc., a Delaware corporation ("Parent"), and each of them, the
attorneys and proxies of the undersigned with full power of substitution and
resubstitution, to the full extent of the undersigned's rights with respect to
(i) the outstanding shares of capital stock of the Company owned of record by
the undersigned as of the date of this proxy, which shares are specified on the
final page of this proxy, and (ii) any and all other shares of capital stock of
the Company which the undersigned may acquire on or after the date hereof. (The
shares of the capital stock of the Company referred to in clauses "(i)" and
"(ii)" of the immediately preceding sentence are collectively referred to as the
"Shares.") Upon the execution hereof, all prior proxies given by the
undersigned with respect to any of the Shares are hereby revoked, and the
undersigned agrees that no subsequent proxies will be given with respect to any
of the Shares.
This proxy is irrevocable, is coupled with an interest, is granted in
connection with the execution and delivery of the Voting Agreement, dated as of
the date hereof, between Parent and the undersigned (the "Voting Agreement") and
is granted in consideration of Parent entering into the Agreement and Plan of
Merger, dated as of the date hereof, among Parent, Gazelle Acquisition Sub, Inc.
and the Company (the "Merger Agreement"); PROVIDED, HOWEVER, that the
undersigned may revoke this proxy under the circumstances specified in Section
8.18(b) of the Voting Agreement.
The attorneys and proxies named above (and their successors) will be
empowered, and may exercise this proxy, to vote the Shares at any meeting of the
stockholders of the Company, however called, or in connection with any
solicitation of written consents from stockholders of the Company, in favor of
the approval and adoption of the Merger Agreement and the approval of the merger
contemplated thereby, and in favor of each of the other actions contemplated by
the Merger Agreement. The undersigned may vote the Shares on all other matters.
This proxy shall be binding upon the representatives, successors and
assigns of the undersigned (including any transferee of any of the Shares).
If any provision of this proxy or any part of any such provision is held under
any circumstances to be invalid or unenforceable in any jurisdiction, then (a)
such provision or
2
<PAGE>
part thereof shall, with respect to such circumstances and in such jurisdiction,
be deemed amended to conform to applicable laws so as to be valid and
enforceable to the fullest possible extent, (b) the invalidity or
unenforceability of such provision or part thereof under such circumstances and
in such jurisdiction shall not affect the validity or enforceability of such
provision or part thereof under any other circumstances or in any other
jurisdiction, and (c) the invalidity or unenforceability of such provision or
part thereof shall not affect the validity or enforceability of
3
<PAGE>
the remainder of such provision or the validity or enforceability of any other
provision of this proxy. Each provision of this proxy is separable from every
other provision of this proxy, and each part of each provision of this proxy is
separable from every other part of such provision.
This proxy shall terminate upon the sooner to occur of the valid termination of
the Voting Agreement and the valid revocation of this proxy pursuant to Section
8.18(b)(i).
Dated: February 28,1999
Warburg, Pincus Capital Partners
Liquidating Trust
By: Stephen Distler
-----------------------------
Stephen Distler, Trustee
Number of shares of common stock of the
Company owned of record as of the date of
this proxy:
3,600,792
---------------------------------
1
