UROMED CORP
DEF 14A, 2000-04-05
SURGICAL & MEDICAL INSTRUMENTS & APPARATUS
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                            SCHEDULE 14A INFORMATION

                  Proxy Statement Pursuant to Section 14(a) of
            the Securities Exchange Act of 1934 (Amendment No.    )

    Filed by the Registrant /X/
    Filed by a party other than the Registrant / /

    Check the appropriate box:
    / /  Preliminary Proxy Statement
    / /  Confidential, for Use of the Commission Only (as permitted by Rule
         14a-6(e)(2))
    /X/  Definitive Proxy Statement
    / /  Definitive Additional Materials
    / /  Soliciting Material Pursuant to Section 240.14a-11(c) or Section
         240.14a-12

                               UROMED CORPORATION
  ------------------------------------------------------------------------------
                (Name of Registrant as Specified In Its Charter)

  ------------------------------------------------------------------------------
    (Name of Person(s) Filing Proxy Statement, if other than the Registrant)

Payment of Filing Fee (Check the appropriate box):

/X/  No fee required

/ /  Fee computed on table below per Exchange Act Rules 14a-6(i)(1)
     and 0-11

    (1) Title of each class of securities to which transaction applies:

        ------------------------------------------------------------------------
    (2) Aggregate number of securities to which transaction applies:

        ------------------------------------------------------------------------
    (3) Per unit price or other underlying value of transaction computed
        pursuant to Exchange Act Rule 0-11 (set forth the amount on which the
        filing fee is calculated and state how it was determined):

        ------------------------------------------------------------------------
    (4) Proposed maximum aggregate value of transaction:

        ------------------------------------------------------------------------
    (5) Total fee paid:

        ------------------------------------------------------------------------

/ / Fee paid previously with preliminary materials.

/ / Check box if any part of the fee is offset as provided by Exchange Act Rule
    0-11(a)(2) and identify the filing for which the offsetting fee was paid
    previously. Identify the previous filing by registration statement number,
    or the Form or Schedule and the date of its filing.

    (1) Amount Previously Paid:

        ------------------------------------------------------------------------
    (2) Form, Schedule or Registration Statement No.:

        ------------------------------------------------------------------------
    (3) Filing Party:

        ------------------------------------------------------------------------
    (4) Date Filed:

        ------------------------------------------------------------------------


<PAGE>
                               UROMED CORPORATION

April 10, 2000

Dear Stockholder:

     You are cordially  invited to attend the Special Meeting of Stockholders of
UroMed  Corporation (the "Company"),  to be held at 9:00 a.m. on Friday, May 12,
2000  at  the  offices  of  Bingham  Dana  LLP,  150  Federal  Street,   Boston,
Massachusetts (the "Meeting").

     The Notice of Special  Meeting and Proxy Statement that follow describe the
business to be considered and acted upon by the stockholders at the Meeting.

     The Board of Directors of the Company  encourages your participation in the
Company's  corporate  governance and, to that end,  solicits your proxy. You may
give your proxy by  completing,  dating,  and  signing  the  enclosed  proxy and
returning it promptly in the enclosed  envelope.  You are urged to do so even if
you plan to attend the  Meeting.  We hope you will be able to join us on May 12,
2000.

Sincerely,

John G. Simon
Chairman of the Board






















              1400 Providence Highway, Norwood, Massachusetts 02062

<PAGE>

                               UROMED CORPORATION

                    NOTICE OF SPECIAL MEETING OF STOCKHOLDERS

                           To Be Held On May 12, 2000
                           --------------------------

     Notice is hereby  given that a Special  Meeting of  Stockholders  of UroMed
Corporation (the "Company") will be held at the offices of Bingham Dana LLP, 150
Federal  Street,  Boston,  Massachusetts  on Friday,  May 12, 2000 at 9:00 a.m.,
local time, to consider and act upon the following matters:

     1) A proposal to elect two Class III directors of the Company, each to hold
a three-year term.
     2) A proposal to adopt the Company's Second Amended and Restated 1991 Stock
Option Plan.
     3) A proposal to ratify the  appointment of  PricewaterhouseCoopers  LLP as
independent accountants of the Company for the current fiscal year.
     4) To transact such other  business as may properly come before the Meeting
or any adjournments thereof.


     This  Special  Meeting  is  being  held  in lieu of an  annual  meeting  of
stockholders  in 2000.  Stockholders of record at the close of business on March
15,  2000 will  receive  notice of the  Meeting  and be  entitled to vote at the
Meeting or any adjournment  thereof.  All stockholders are cordially  invited to
attend the Meeting.  Information  relating to the matters to be  considered  and
voted on at the Special Meeting is set forth in the proxy statement accompanying
this Notice.

                       BY ORDER OF THE BOARD OF DIRECTORS

April 10, 2000

     THE BOARD OF DIRECTORS IS SOLICITING THE ENCLOSED PROXY. WHETHER OR NOT YOU
EXPECT TO BE PRESENT AT THE MEETING,  COMPLETE, DATE AND SIGN THE ENCLOSED PROXY
AND RETURN IT IN THE PRE-ADDRESSED  ENVELOPE  PROVIDED FOR THAT PURPOSE.  IF YOU
ATTEND THE MEETING,  YOU MAY  WITHDRAW THE ENCLOSED  PROXY GIVEN BY YOU AND VOTE
YOUR SHARES IN PERSON


  /s/ Donald-Bruce Abrams
___________________________
           CLERK
<PAGE>

                               UROMED CORPORATION
                             1400 Providence Highway
                                Norwood, MA 02062

                                 ---------------
                                 PROXY STATEMENT
                                ----------------

     INTRODUCTION.  This Proxy  Statement is furnished  in  connection  with the
solicitation  by the Board of Directors of UroMed  Corporation,  a Massachusetts
corporation  (the  "Company"),  of  proxies  for  use at a  Special  Meeting  of
Stockholders  (the "Meeting") to be held at the offices of Bingham Dana LLP, 150
Federal Street, Boston, Massachusetts on Friday May 12, 2000 at 9:00 a.m., local
time, and at any adjourned  session thereof.  This Special Meeting is being held
in lieu of an annual meeting of  stockholders  in 2000. This Proxy Statement and
the enclosed Annual Report to Stockholders  for the Company's  fiscal year ended
December 31, 1999 are being mailed to  stockholders  on or about April 10, 1999.
The Annual Report does not constitute any part of this Proxy Statement.

     SOLICITATION.  The entire cost of preparing,  assembling,  and mailing this
proxy  material  will be borne by the  Company.  In  addition,  the  Company may
reimburse  brokerage  firms and other persons  representing  certain  beneficial
owners of shares for their reasonable  expenses in sending proxy material to and
obtaining proxies from such beneficial owners.

     REVOCATION.  A proxy may be revoked by a  stockholder  at any time prior to
its use by giving written notice of such revocation to the Clerk of the Company,
by appearing at the Meeting and voting in person,  or by returning a later dated
proxy in the form enclosed.

     QUORUM AND  VOTING.  Stockholders  of record as of the close of business on
March 15, 2000 will be entitled to vote at the Meeting.  As of such record date,
there were issued and outstanding  and entitled to vote 5,175,162  shares of the
common  stock,  no par value,  of the Company (the "Common  Stock").  Holders of
shares of Common  Stock are  entitled  to one vote for each  share  owned at the
record  date on all  matters to come  before the  Meeting  and any  adjournments
thereof.  The  presence  in person or by proxy of holders  of a majority  of the
shares of Common Stock entitled to vote at the Meeting  constitutes a quorum for
the transaction of business.

     TABULATION  OF VOTES.  All  proxies  will be voted in  accordance  with the
instructions  contained  therein.  If no  choice  is  specified  for one or more
proposals  in a proxy  submitted  by or on behalf of a  stockholder,  the shares
represented  by such proxy will be voted in favor of such  proposals and, in the
discretion of the named  proxies,  with respect to any other  proposals that may
properly come before the Meeting.  Broker  non-votes (if the broker has voted on
at least one proposal) and proxies that withhold  authority to vote for election
of a director or that reflect abstentions will be deemed present for the purpose
of  determining  the presence of a quorum for the  transaction  of  business.  A
broker  non-vote will have no effect on the outcome of voting on such  proposal.
An abstention  with respect to a proposal will have the effect of a vote against
such proposal.

     The Board of  Directors  does not know of any matters  that will be brought
before the Meeting other than those matters specifically set forth in the Notice
of Special Meeting of Stockholders.  However, if any other matter properly comes
before the Meeting,  it is intended  that the persons named in the enclosed form
of proxy, or their  substitute  acting  thereunder,  will vote on such matter in
accordance with their best judgment.


                                       1
<PAGE>

            STOCK OWNERSHIP OF PRINCIPAL STOCKHOLDERS AND MANAGEMENT

     The following table sets forth certain information regarding the beneficial
ownership of the Company's Common Stock as of March 10, 2000 for (i) each person
who is known by the Company to own beneficially  more than 5% of the outstanding
shares of Common  Stock (ii) each  director  of the  Company,  (iii) each of the
executive  officers of the Company as named in the Summary  Compensation  Table,
and (iv) all of the directors and officers of the Company as a group.

<TABLE>
<CAPTION>
                                                                     Shares Beneficially Owned (1)
                                                                     _____________________________
<S>                                                                      <C>            <C>
Name and address                                                         Number         Percent
- ----------------                                                         _________      _______
John G. Simon........................................................    562,056(2)      10.8%
     c/o UroMed Corporation, Building No. 2
     1400 Providence Highway, Norwood, MA 02062
Daniel Muscatello....................................................      8,677(3)        *
Richard A. Sandberg..................................................      1,834(4)        *
Thomas E. Tierney....................................................      2,400(5)        *
Elizabeth B. Connell, M.D............................................      7,850(6)        *
E. Kevin Hrusovsky(7)................................................       --             --
Domenic C. Micale....................................................      1,110(8)        *
All directors and executive officers as a group (7 persons)........      562,090(9)      10.8%
</TABLE>

- --------------------------

*   Less than 1%.

     (1) Unless  otherwise  indicated in these  footnotes,  each stockholder has
sole voting and investment power with respect to the shares  beneficially owned.
Includes  shares  issuable upon exercise of options  exercisable as of March 10,
2000 or within 60 days after such date.
     (2) Includes (i) 6,584 shares held by The Clarendon 1993 Irrevocable Trust,
of which Mr. Simon is a Trustee and over which Mr. Simon shares  investment  and
voting control,  (ii) 10,694 shares issuable upon exercise of stock options, and
(iii) 21,837  shares  issuable  upon exercise of stock options held by directors
and  officers  of the Company  with respect to which Mr. Simon has the right to
direct the vote pursuant to  contractual  relationships  between the Company and
such persons.
     (3) Represents 8,677 shares issuable upon exercise of stock options.
     (4) Includes  1,800 shares  issuable  upon exercise of stock  options.
     (5) Represents 2,400 shares issuable upon exercise of stock options.
     (6) Represents 7,850 shares issuable upon exercise of stock options.
     (7) Mr.  Hrusovsky  was elected to the Board of Directors on March 29, 2000
and filled the vacancy created by Mr. David P. Fialkow who resigned effective as
of that date.
     (8) Represents 1,110 shares issuable upon exercise of stock options.
     (9)  Includes  32,531  shares  issuable  upon  exercise  of stock  options,
including  21,837  shares  issuable  upon  exercise  of  stock  options  held by
directors  and officers of the Company,  all of the  ownership of which has been
attributed soley to Mr. Simon.


                                   PROPOSAL 1

                              ELECTION OF DIRECTORS

     The Company's  Board of Directors is divided into three classes,  with each
class having two directors  each,  with the members of each such class serving a
three year term.  Each year the Company's  stockholders  have the opportunity to
elect the  members of one class.  At the  Meeting,  the terms of the  members of
Class III, Mr. John G. Simon and Richard A. Sandberg,  expire. Mr. Simon and Mr.
Sandberg are the only nominees for election as Class III  Directors,  for a term
to expire at the 2003 Annual Meeting of Stockholders.

     Unless  authority is withheld,  it is the  intention of the persons  voting
under the  enclosed  proxy to vote such  proxy in favor of the  election  of Mr.
Simon and Mr.  Sandberg to be  directors  of the  Company  until the 2003 Annual
Meeting of  Stockholders  and until their  successors are elected and qualified.
The  affirmative  vote of a plurality of the shares of Common  Stock  present or
represented  at the Meeting by proxy is required  for the  election of Mr. Simon
and Mr. Sandberg as Class III directors.


                                       2
<PAGE>

     The Class I directors of the Company with terms expiring at the 2001 Annual
Meeting of Stockholders are Daniel Muscatello and Dr. Elizabeth E. Connell.  The
Class II directors of the Company with terms expiring at the 2002 Annual Meeting
of  Stockholders  are Mr.  Thomas E.  Tierney  and Mr. E. Kevin  Hrusovsky.  Mr.
Hrusovsky  was elected a Director by vote of the Board of Directors on March 29,
2000 in order to fill the vacancy created by Mr. David P. Fialkow's  resignation
as a Director on that date.


     THE BOARD OF DIRECTORS  UNANIMOUSLY  RECOMMENDS THAT ALL STOCKHOLDERS  VOTE
"FOR" EACH OF THE NOMINEES.


     The following table sets forth, with respect to the members of the Board of
Directors,  the name,  age,  length of service as a director  and any service on
committees of the Board of Directors of the Company.  For information  regarding
the number of shares of the Company's Common Stock owned by each nominee and all
directors as of March 10, 2000, see "Stock  Ownership of Principal  Stockholders
and  Management." The address for each person listed below is c/o the Company at
1400 Providence Highway, Norwood, MA 02062.
<TABLE>
<CAPTION>
                                                               Year First    Positions and
                                                               Became        offices with
Name                                                  Age      Director      the Company
- -----                                                 ---     ----------     -------------
<S>                                                   <C>        <C>         <C>
John G. Simon...................................      37         1990        Chairman of the
                                                                             Board, Director
                                                                             and former
                                                                             President and Chief
                                                                             Executive Officer
Daniel Muscatello...............................      44         1999        Director, President
                                                                             and Chief Executive
                                                                             Officer
Elizabeth B. Connell, M.D.......................      74         1994        Director
Richard A. Sandberg (l).........................      57         1991        Director
Thomas E. Tierney (l)...........................      72         1991        Director
E. Kevin Hrusovsky (1)(2).......................      38         2000        Director
</TABLE>
- --------------------------
     (1) Member of the  Compensation  Committee and Audit Committee of the Board
of Directors.
     (2) Mr.  Hrusovsky  was  elected  to the Board of  Directors on March 29,
2000 to replace David P. Fialkow who resigned at that date.

BACKGROUND OF DIRECTORS

     John G. Simon, Chairman of the Board of Directors, and former President and
Chief Executive  Officer.  Mr. Simon is the founder of the Company and served as
President and Chief Executive  Officer of the Company from its inception in 1990
until  December  1999,  and as Chairman of the Board of Directors of the Company
since its inception in 1990.

     Daniel Muscatello,  Director,  President and Chief Executive  Officer.  Mr.
Muscatello  joined the Company in February 1997 as Director of Marketing and was
appointed  Vice  President  of  Marketing  and Sales in 1998.  He was  appointed
President and Chief Executive Officer in December 1999 at which time he was also
elected a member of the  Company's  Board of  Directors.  Prior to  joining  the
Company,  Mr.  Muscatello  held management  positions as Healthcare  Consultant,
Corporate  Account Executive and Region Manager with Baxter Healthcare from 1993
to 1997.  Prior to that,  Mr.  Muscatello  was Director of  Marketing  for Alcon
Laboratories, Inc. Systems Division from 1991 to 1993.

     Elizabeth B. Connell,  M.D., Director. Dr. Connell has served as a Director
of the Company  since 1994.  Since  1981,  she has served as a professor  in the
Department of Gynecology and Obstetrics at Emory  University  School of Medicine
in Atlanta,  Georgia and was appointed  Professor  Emeritus effective January 1,
1997.  Dr.  Connell also  currently  serves as a consultant to the U.S. Food and
Drug Administration's OB/GYN Devices Panel.

                                       3
<PAGE>

     Richard A. Sandberg, Director. Mr. Sandberg has served as a Director of the
Company since 1991. Mr. Sandberg is a private investor and serves as Chairman of
the Board of  Directors of numerous  private  companies.  From 1983 to 1997,  he
served in a variety  of  positions  at DIANON  Systems  Inc.,  an  oncology  and
gynecology  marketing  and  database  firm which he  co-founded,  most  recently
serving as Chairman and Chief Executive  Officer.  Mr. Sandberg is a director of
Matritech, Inc. a manufacturer of oncology diagnostic test technologies.

     Thomas E. Tierney,  Director.  Mr.  Tierney has served as a Director of the
Company since 1991. He has served as the Chairman of T.E.T. Associates, a health
care  consulting  firm,  since 1988 and as the  Chairman of  Warehouse  Products
Testing  Corp.  from 1994 to 1996.  He was  formerly  with Kendall Co., a health
products  firm,  from 1951 to 1988 where he held  numerous  positions  including
Executive  Vice  President and General  Manager of the  Healthcare  Division and
Group Executive for the Health Care Business.  Mr. Tierney is also a Director of
Procyte Corporation.

     E. Kevin Hrusovsky,  Director.  Mr. Hrusovsky was elected a Director of the
Company on March 29, 2000. He has served as the  President  and Chief  Executive
Officer of Zymark Corporation, a provider of products, technologies and services
for laboratory applications since 1996. He was formerly with FMC Corporation,  a
producer of chemicals and machinery for industry and  agriculture,  from 1992 to
1996, where he held management positions as International Director, Agricultural
Products Group, Division Manager,  Pharmaceutical and Global Sales and Marketing
Director, Pharmaceutical.


                   BOARD OF DIRECTORS MEETINGS AND COMMITTEES

     During the  Company's  fiscal year ended  December 31,  1999,  the Board of
Directors held five meetings.

     Each  of the  Audit  Committee  of  the  Board  of  Directors  (the  "Audit
Committee")  and the  Compensation  Committee  of the  Board of  Directors  (the
"Compensation Committee") presently are composed of three directors:  Richard A.
Sandberg, Thomas E. Tierney and E. Kevin Hrusovsky. Mr. Hrusovsky was elected to
the Audit Committee and Compensation  Committee on March 29, 2000 and filled the
vacancies  on those  committees  created by Mr.  David P.  Fialkow who  resigned
effective  as of that  date.  Responsibilities  of the Audit  Committee  include
engagement of  independent  accountants,  review of audit fees,  supervision  of
matters relating to audit functions,  review of internal policies and procedures
regarding audits, accounting and other financial controls, and reviewing related
party  transactions.  During  1999,  the  Audit  Committee  held  two  meetings.
Responsibilities of the Compensation  Committee include approval of remuneration
arrangements  for  executive  officers of the  Company,  review and  approval of
compensation  plans  relating to  executive  officers and  directors,  including
grants of stock  options  and other  benefits  under the  Company's  Amended and
Restated  1991 Stock  Option Plan (the "1991 Stock  Option  Plan"),  and general
review  of the  Company's  employee  compensation  policies.  During  1999,  the
Compensation Committee held two meetings.

           COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION

     The Company's  Compensation  Committee  currently consists of three outside
directors,  Richard A. Sandberg,  Thomas E. Tierney and E. Kevin Hrusovsky.  Mr.
Hrusovsky was elected to the Compensation Committee on March 29, 2000 and filled
the vacancy  created by Mr. David P.  Fialkow who resigned  effective as of that
date. No member of the Compensation  Committee is a former or current officer or
employee  of the  Company.  To the  Company's  knowledge,  there  were no  other
relationships  involving  members of the  Committee  or other  directors  of the
Company requiring disclosure in this Proxy Statement.


                                       4
<PAGE>


                             EXECUTIVE COMPENSATION

     The following  table sets forth certain  compensation  information  for the
fiscal  years  ended  December  31,  1999,  1998 and 1997  with  respect  to the
Company's Chief Executive  Officer,  former Chief Executive  Officer and all the
other most highly  compensated  executive  officers  of the Company  whose total
salary and bonuses for the fiscal year indicated exceeded $100,000.


                           SUMMARY COMPENSATION TABLE

<TABLE>
<CAPTION>


<S>                                           <C>     <C>         <C>        <C>           <C>
                                                                             SECURITIES    ALL OTHER
                                                                             UNDERLYING    COMPEN-
NAME AND PRINCIPAL POSITION                   YEAR    SALARY      BONUS       OPTIONS       SATION
- ---------------------------------------       -----   ----------  ---------  ----------    ---------
John G. Simon
  Chairman of the Board and former            1999    $225,000(1) $63,000(2)      --       $  --
  Chief Executive Officer & President         1998     225,000(1)  39,375(2)   12,992(3)      --
                                              1997     167,522       --         2,900(3)      --
Daniel Muscatello
  President and Chief Executive Officer       1999     147,896     30,040(2)   85,989         --
                                              1998     138,202     17,000(2)   29,400(4)      --
                                              1997     119,827     16,000(2)    3,200(4)    52,000(5)
Domenic C. Micale
  Vice President Finance and Treasurer        1999      93,333     15,582(2)    3,000         --
                                              1998      71,249      4,620(2)   18,600(6)      --
                                              1997      64,347      6,250(2)    1,080(6)      --

</TABLE>

- -------------------------
     (1) Includes  $56,475 of deferred salary for 1998 that was paid in February
1999.
     (2) Bonus amounts  reflected  for 1999,  1998 and 1997 relate to such years
but were paid in February 2000, 1999 and 1998, respectively.
     (3) 1998 stock option grants include 12,992 stock options that were granted
in prior years and repriced in 1998. The options repriced were originally issued
as  follows:  3,292 in 1993,  2,400 in 1995,  4,400 in 1996,  and 2,900 in 1997.
These options were both canceled and reissued in 1998.
     (4) 1998 stock option grants include 7,200 stock options, originally issued
in 1998 and repriced  later in 1998. Of these  repriced  options in 1998,  3,200
were originally issued in 1997. These options were both canceled and reissued in
1998.
     (5) 1997 amount pertains to relocation and related payments.
     (6) 1998 stock option grants include 1,800 stock options, originally issued
in 1998 and repriced  later in 1998. Of these  repriced  options in 1998,  1,080
options were  originally  issued in 1997.  These  options were both canceled and
reissued in 1998.



                                       5
<PAGE>



                        Option Grants in Last Fiscal Year
                                Individual Grants
<TABLE>
<CAPTION>
                                                                           Potential Realizable Value
                    Number of       % of Total                             at Assumed Annual Rate of
                   Securities      Options Granted                         Stock Price Appreciation
                    Underlying     to Employees in    Exercise    Expiration    for Option Term
                 Options Granted    Fiscal Year    Price ($/sh)   Date            5%           10%
                       (1)
                 ---------------  ---------------- ------------  --------- ---------------------------
<S>                    <C>             <C>           <C>         <C>            <C>          <C>
John G. Simon            --              --          $ --           --          $  --        $   --


Daniel Muscatello      12,000           8.57%         1.38        8/11/09        10,377        26,297
                       73,989          52.85%         1.09       12/16/09        50,905       129,004

Domenic C. Micale       3,000           2.14%         1.38        8/11/09         2,594         6,574


</TABLE>

- -------------------------

     (1) Grants under the 1991 Stock Option Plan. These options have a four-year
vesting period,  with 12.5% vesting after the first six months and the remainder
monthly at a rate of 2.08% per month for the remaining  forty-two  months.  Such
options  are not  transferable,  other than by will or the laws of  descent  and
distribution.




     Option Exercises in Last Fiscal Year and Fiscal Year End Option Values

<TABLE>
<CAPTION>
                                                                             Value of Unexercised
                    Number of     Value    Number of Securities Underlying       In-the-Money
               Shares Acquired  Realized   Unexercised Options at 12/31/99    Options at 12/31/99(2)
Name             on Exercise       (1)     Exercisable      Unexercisable   Exercisable  Unexercisable
- -----          ---------------  --------   -------------------------------- --------------------------
<S>                   <C>        <C>            <C>           <C>              <C>         <C>
John G. Simon         --         $  --          9,925           3,067          $  --       $  --
Daniel Muscatello     --            --          5,543         102,646             --          --
Domenic C. Micale     --            --          4,370          15,430             --          --

</TABLE>
 - ------------------------

     (1) Value realized is based on the fair market value of the Common Stock as
of the date of exercise minus the exercise price.
     (2) Value is based on the closing  sale price of the Common Stock as of the
last business day of the year, minus the exercise price.



                                       6
<PAGE>

                  EMPLOYMENT AGREEMENTS WITH EXECUTIVE OFFICERS

     The  Company  entered  into an amended  employment  agreement  with  Daniel
Muscatello as President  and Chief  Executive  Officer on December 1, 1999.  The
agreement  is  renewable  at the option of both  parties and provides for (i) an
annual base salary of $200,000 subject to annual review and increase,  (ii) such
incentive bonus payments as the Company may from time to time  determine,  (iii)
severance  payments  equal to twelve  months' base salary and medical  insurance
costs in the event that Mr.  Muscatello's  employment  terminates other than for
cause. Mr. Muscatello's employment agreement also provides for assignment to the
Company of his rights to inventions  and  proprietary  information  and contains
confidentiality and non-competition provisions.

     The Company has entered into an "at-will" employment agreement with Domenic
C. Micale for an initial term of five years, dated as of September 30, 1996. The
agreement  with Mr. Micale  provides for such  incentive  bonus  payments as the
Company may from time to time determine. The current semi-monthly salary for Mr.
Micale is $4,375. This salary is subject to annual review and adjustment.

     The employment agreement between the Company and John G. Simon with respect
to Mr.  Simon's  position as President and Chief  Executive  Officer  expired on
March 17, 1999.  That agreement  provided for an annual base salary of $225,000.
See "Director  Compensation"  below for a description  of the new agreement with
Mr. Simon with respect to his capacity as Chairman of the Board of Directors.


                              DIRECTOR COMPENSATION

     The  Company  pays  the  travel  expenses  of  non-employee  directors  for
attendance at meetings of the Board of Directors and  committees  thereof.  Cash
compensation  of $500 per meeting and a $2,000  annual  retainer  per person was
paid to the Directors in 1999. In 2000, cash  compensation of $1,000 per meeting
and a $5,000 annual retainer per person will be paid to the Directors.

     In addition,  under the terms of the 1991 Stock  Option  Plan,  as amended,
each non-employee  director of the Company receives  quarterly grants of options
to purchase  500 shares of the Common Stock  effective  as of May 12, 2000,  and
each  non-employee  director who is first  elected to the Board after January 1,
2000 will receive options to purchase 10,000 shares of Common Stock.

     The Company  entered into an employment  agreement  with John G. Simon with
respect  to his  position  as  Chairman  of the  Board of  Directors  commencing
December 1, 1999 and  continuing  until March 31,  2001.  The  agreement  may be
extended  thereafter only by written agreement of the Company and Mr. Simon. The
agreement with Mr. Simon provides for an annual salary of $225,000.


             COMPENSATION COMMITTEE REPORT ON EXECUTIVE COMPENSATION

     COMPENSATION PHILOSOPHY

     The objectives of the Company's executive compensation program are to align
compensation with business objectives and individual performance,  and to enable
the Company to attract,  retain and reward executive  officers who contribute to
the  long-term  success of the Company.  The  Company's  executive  compensation
philosophy is based on the following principles:

     - Competitive and Fair Compensation

     The Company is committed to  providing  an executive  compensation  program
that helps  attract  and retain  highly  qualified  executives.  To ensure  that
compensation is competitive,  the Company  compares its  compensation  practices
with those of  comparable  medical  products and other  relevant  companies in a
similar stage of development. The Company also seeks to achieve a balance of the
compensation paid to a particular  individual and the compensation paid to other
executives both inside the Company and at comparable companies.

                                       7
<PAGE>

     - Short-term Cash Compensation

     Cash  compensation  consists  of two  components:  annual  salary  and cash
incentive  compensation.  The annual  salaries  of the  executive  officers  are
evaluated based upon corporate and individual performance. Corporate performance
is evaluated by reviewing the extent to which  strategic and business plan goals
and  milestones  are met.  Individual  performance  is  evaluated  by  reviewing
attainment of specified  individual  objectives and milestones and the degree to
which teamwork and Company values are fostered.  Cash incentive  compensation is
based upon the achievement of functional, divisional and corporate goals as well
as individual performance.

     - Long-term Incentive Compensation

     Because not all short-term management  accomplishments are directly related
to changes in short-term  stockholder value, the Compensation Committee believes
that management should also have a long-term  compensation  component related to
increasing  stockholder  value.  To assure that  executive  officers'  goals and
accomplishments  are linked with increasing  stockholder value, the Compensation
Committee  believes that the grant of options to purchase the  Company's  Common
Stock that  become  exercisable  over an  extended  period of time  should be an
integral part of the overall compensation philosophy.


     COMPENSATION PROGRAM COMPONENTS

     Annual compensation for the Company's executive officers currently consists
of  three   elements  -  salary,   cash   incentive   compensation   and  equity
participation.  Executive  officers are also entitled to participate in the same
benefit plans available to other employees.  In setting the base salaries of the
Company's  executive officers,  the Compensation  Committee reviews the range of
compensation  paid to  employees  in similar  positions  of the  companies  in a
similar state of development in the medical and other relevant industries. While
industry-wide  practices are deemed to be important  indicators  of  appropriate
compensations  levels,  the Compensation  Committee  believes the most important
considerations  are  individual  and  corporate   performance,   in  setting  an
executive's base salary and cash incentive compensation.

     On an annual basis, goals for Company  performance and individual goals and
objectives  for each of the Company's  executive  officers  (including the Chief
Executive  Officer) are  established by the  Compensation  Committee.  Every six
months,  all  executive  officers  other than the Chief  Executive  Officer  are
evaluated by the Chief Executive  Officer on their  performance  with respect to
their  individual  short-term  goals  and  objectives.  At  this  time,  revised
quarterly goals and objectives are established, if appropriate. Based upon their
performance relative to their goals and objectives, the base salary of executive
officers other than the Chief Executive  Officer is generally  adjusted once per
year by the Compensation Committee.

     On an annual basis, the Compensation Committee evaluates the achievement of
the annual goals and objectives  established for the Chief Executive Officer and
his contribution to the Company.

     In February 2000, the Company paid cash bonuses aggregating $108,622 to its
Chief  Executive  Officer,  Vice President of Finance and former Chief Executive
Officer.  The  Compensation  Committee  intended for these  bonuses to represent
compensation   for  such  officers'   contributions   to  the   development  and
achievements of the Company to December 31, 1999,  including  reducing operating
losses,  reducing debt levels and disposing of assets unrelated to the Company's
prostate  cancer focus.  For the Company's  2000 fiscal year,  the  Compensation
Committee has set additional  goals and objectives for Company  performance,  as
well as  additional  individual  goals and  objectives,  with the  intention  of
reviewing the appropriateness of additional incentive cash compensation for such
year.  Please refer to the table entitled  "Summary  Compensation"  elsewhere in
this Proxy  Statement  for  information  relating to the base  salaries and cash
bonus  payments made during the Company's last three  completed  fiscal years to
certain of its executive officers.


                                       8
<PAGE>

    Stock  option  awards are  designed  to promote the  identity of  long-term
interests between the Company's employees and its stockholders and assist in the
retention of executives.  The size of option grants is generally intended by the
Compensation  Committee to reflect the executive's position with the Company and
his or her actual or potential  contributions  to the Company in relation to his
or her overall  compensation.  The  Compensation  Committee  believes that stock
options  have  been  and  remain  an  excellent  vehicle  for  compensating  its
employees.  Because the option  exercise  price of the employee is generally the
fair market value of the stock on the date of grant,  employees recognize a gain
only if the value of the stock increases. Thus, employees with stock options are
rewarded for their efforts to improve the  long-term  value of the Common Stock.
Stock options, moreover, have been used to reward substantially all employees of
the  Company,  not just at the  executive  officer  level.  The  option  program
typically uses a four-year or greater  vesting period to encourage  employees to
continue  in the  employ of the  Company.  Please  refer to the  table  entitled
"Option  Grants in Last  Fiscal  Year"  elsewhere  in this Proxy  Statement  for
information regarding option grants to certain executive officers.



      1999 COMPENSATION FOR THE CHAIRMAN AND FORMER CHIEF EXECUTIVE OFFICER

     The amount and means of determining Mr. Simon's base annual salary for 1999
was fixed by the terms of his employment  agreement with the Company,  which was
effective as of March 17, 1997. That employment agreement provided for an annual
base salary for 1999 of $225,000.  On December 1, 1999, the Company entered into
a new  employment  agreement  with Mr.  Simon with  respect to his  position  as
Chairman of the Board of Directors,  which provides for the same $225,000 annual
base salary.

                1999 COMPENSATION FOR THE CHIEF EXECUTIVE OFFICER

     The amount and means of determining Mr. Muscatello's base annual salary for
1999  was  fixed by the  terms  of his  amended  employment  agreement  with the
Company,  which was  effective as of December 1, 1999.  This amended  employment
agreement  provides  for an annual  base salary of  $200,000,  subject to yearly
review and  increase,  and such  incentive  bonus  payments as the  Compensation
Committee  may from time to time  determine.  Mr.  Muscatello's  current  annual
salary is $200,000.


              COMPLIANCE WITH INTERNAL REVENUE CODE SECTION 162 (M)

     The  Compensation  Committee has not yet had the occasion to adopt a policy
on the 1993  amendment  to the Internal  Revenue  Code of 1986,  as amended (the
"Code"),  disallowing  deduction  on  compensation  in excess of $1 million  for
certain  executives  of public  companies.  The Company  believes  that  options
granted  under the 1991 Stock  Option Plan are exempt from the  limitation,  and
other  compensation  expected  to be paid  during  fiscal year 1998 is below the
compensation limitation.

Compensation Committee


Richard A. Sandberg
Thomas E. Tierney
E. Kevin Hrusovsky
                                       9
<PAGE>

                      SHAREHOLDER RETURN PERFORMANCE GRAPH

     The following graph compares the performance of the Company's  Common Stock
to the NASDAQ Stock Market  Total Return Index for U.S.  Companies  (the "NASDAQ
Stock  Market-U.S.  Index") and the  Chase H&Q Growth Index ("Chase H&Q Growth
Index") over the period from the time of the Company's  initial public  offering
of Common Stock on March 16, 1994 to December 31, 1999.  The graph  assumes that
the value of an investment in the Company's Common Stock and each index was $100
at March 16, 1994 and that all dividends were reinvested.

                   TABLE OF PLOT POINTS FOR PERFORMANCE GRAPH
 <TABLE>
<CAPTION>
                                                                   NASDAQ STOCK
   DATES              UROMED CORP.        CHASE H&Q GROWTH          MARKET-U.S.
   ------             -----------         ----------------         -------------
   <S>                  <C>                    <C>                    <C>
   Dec-94               100.00                 100.00                 100.00
   Jan-95               107.95                  99.44                 100.53
   Feb-94               129.55                 106.35                 105.81
   Mar-95               125.00                 111.54                 108.95
   Apr-95               127.27                 112.24                 112.38
   May-95               111.36                 111.79                 115.29
   Jun-95               147.73                 126.16                 124.62
   Jul-95               154.55                 144.12                 133.77
   Aug-95               172.73                 147.92                 136.49
   Sep-95               181.82                 157.36                 139.63
   Oct-95               193.18                 158.37                 138.83
   Nov-95               184.09                 164.92                 142.09
   Dec-95               234.09                 166.89                 141.33
   Jan-96               243.18                 166.38                 142.04
   Feb-96               254.55                 172.78                 147.46
   Mar-96               209.09                 172.18                 147.95
   Apr-96               190.91                 199.58                 160.21
   May-96               220.45                 210.76                 167.56
   Jun-96               250.00                 188.55                 160.01
   Jul-96               231.82                 156.97                 145.76
   Aug-96               188.64                 169.86                 153.94
   Sep-96               200.00                 188.45                 165.70
   Oct-96               184.09                 174.73                 163.87
   Nov-96               165.91                 172.23                 174.04
   Dec-96               177.27                 174.68                 173.89
   Jan-97               156.82                 183.73                 186.23
   Feb-97               147.73                 163.93                 175.93
   Mar-97               134.09                 140.95                 164.46
   Apr-97                70.45                 133.26                 169.58
   May-97                86.36                 161.33                 188.79
   Jun-97                63.64                 164.62                 194.59
   Jul-97                68.18                 175.28                 215.10
   Aug-97               105.68                 179.56                 214.79
   Sep-97               120.45                 198.43                 227.52
   Oct-97               105.68                 186.48                 215.67
   Nov-97                90.91                 178.51                 216.81
   Dec-97                64.20                 179.41                 213.07
   Jan-98                69.32                 177.66                 219.82
   Feb-98                42.61                 199.28                 240.49
   Mar-98                29.55                 213.37                 249.36
   Apr-98                37.50                 218.73                 253.57
   May-98                28.86                 197.96                 239.49
   Jun-98                20.23                 214.69                 256.21
   Jul-98                 9.43                 196.90                 253.22
   Aug-98                 4.66                 147.22                 203.17
   Sep-98                 4.66                 176.51                 231.37
   Oct-98                 5.91                 186.86                 241.36
   Nov-98                 7.16                 222.58                 263.78
   Dec-98                 5.23                 260.24                 300.25
   Jan-99                 7.50                 322.68                 343.91
   Feb-99                 5.57                 288.08                 313.08
   Mar-99                 4.32                 322.58                 335.86
   Apr-99                 5.91                 345.45                 345.30
   May-99                 5.57                 331.61                 337.34
   Jun-99                 5.00                 369.51                 367.47
   Jul-99                 4.66                 361.50                 362.12
   Aug-99                 4.32                 376.51                 376.46
   Sep-99                 4.09                 400.30                 375.85
   Oct-99                 4.20                 445.02                 403.16
   Nov-99                 3.75                 537.33                 446.17
   Dec-99                 3.98                 729.00                 542.43
</TABLE>


                                       10
<PAGE>

                                   PROPOSAL 2

                    Adoption of the Company's Second Amended
                       and Restated 1991 Stock Option Plan

     Effective  August 15, 1995,  the Company's  Amended and Restated 1991 Stock
Option Plan (the  "Amended  and  Restated  Plan") was amended for the purpose of
providing for the grant of formula stock options ("Formula Grants") to directors
who are not  officers or employees  of the Company  (the  "Outside  Directors").
Prior to the adoption of such amendments,  members of the Compensation Committee
were ineligible for grants of options under the 1991 Stock Option Plan.

     The Board of Directors has  considered and approved  certain  amendments to
the Amended and Restated 1991 Stock Option Plan, resulting in the Second Amended
and Restated 1991 Stock Option Plan (the "Second  Amended and Restated  Plan" or
the "Plan") and is proposing the Second  Amended and Restated Plan, as it amends
the existing Amended and Restated Plan, for stockholder approval.

     Because as of March 10,  2000,  options to purchase an aggregate of 287,394
shares of Common Stock have been granted and  exercised  from 1991 to date,  and
options to  purchase  274,377  shares of Common  Stock are  currently  issued to
current  employees,  officers and directors,  only 78,229 shares of Common Stock
remain  available  for issuance in the future.  Among other  things,  the Second
Amended  and  Restated  Plan  increases  the  number of  shares of Common  Stock
authorized  for issuance in an effort to replace  those  options which have been
granted and exercised since 1991.

     The Second  Amended and Restated  Plan amends the Amended and Restated Plan
by making the following changes:

     1. Increasing the number of authorized  shares of Common Stock reserved for
issuance pursuant to stock options from 640,000 shares to 890,000 shares;

     2. Changing the number of shares issuable pursuant to stock options granted
to Outside  Directors elected after January 1, 2000 on the date of such election
from 4,000 shares to 10,000 shares ("Up-Front Formula Grants");

     3. Changing the vesting  period for such Up-Front  Formula  Grants from six
(6) equal  installments over six (6) years to three (3) equal  installments over
three (3) years;

     4.  Changing  the number of shares of Common  Stock  issuable  pursuant  to
quarterly Formula Grants ("Quarterly Formula Grants") commencing on May 15, 2000
from 150 shares to 500 shares; and

     5.  Eliminating the restriction  that no Outside  Director may receive more
than 24 Quarterly Formula Grants.

     As of March 10, 2000, 37  individuals  were eligible to  participate in the
Plan. As of March 10, 2000, 561,771 shares were issued or issuable upon exercise
of options granted  according to the Plan, and options to purchase an additional
78,229 shares remained available for grant.

     The Board of Directors  has directed  that the Second  Amended and Restated
Plan be submitted to the  stockholders  in its entirety for approval in order to
meet the requirements of the Nasdaq Stock Market,  Inc.  applicable to companies
with securities listed on the Nasdaq SmallCap Market.

     The Board of Directors  believes that the Second  Amended and Restated Plan
will  enable the Company to continue  its general  practice of making  grants of
stock options to employees,  Outside  Directors and  consultants to the Company,
thereby  encouraging  stock  ownership by such persons and providing  additional
incentives for them to promote the success of the Company's business.

                                       11
<PAGE>

     Set forth below is a summary of certain  provisions  of the Second  Amended
and  Restated  Plan and a general  description  of the Federal  income tax rules
applicable  to the grant and  exercise of stock  options  under such Plan.  This
summary does not purport to be complete  and is subject to and  qualified in its
entirety by reference to the  complete  text of the Second  Amended and Restated
Plan,  which is  attached  hereto as  Appendix 1 and is  incorporated  herein by
reference.

     Purpose of the Plan.  The purpose of the Plan is to encourage  ownership of
the Company's  Common Stock by employees,  Outside  Directors and consultants to
the Company and its subsidiaries and to provide  additional  incentives for them
to endeavor for the success of the Company's business.

     Administration.  The Plan is  administered by the  Compensation  Committee.
Subject to the provisions of the Plan, the Compensation Committee has discretion
to determine  when awards are made,  which  employees  are granted  awards,  the
number of shares  subject  to each  award  and all other  relevant  terms of the
awards.  The  Compensation  Committee also has broad  discretion to construe and
interpret the Plan and adopt rules and regulations thereunder.

     Eligibility.  Awards  may be  granted  under  the Plan to  persons  who are
employees,  Outside  Directors or  consultants  to the Company or a  subsidiary.
These eligible  employees include officers and directors of the Company,  except
that no member of the  Compensation  Committee  is eligible  to receive  options
under the Plan other than pursuant to Formula Grants.

     Shares  Subject to the Plan.  The Plan provides that options to purchase up
to an aggregate of 890,000 shares of Common Stock may be granted.  This limit is
subject to adjustment for stock dividends,  stock splits or other changes in the
Company's capitalization. In addition, any option that expires or terminates for
any reason  without  having been exercised may be reissued under the Plan. As of
December  31,  1999,  246,696  shares had been issued  upon  exercise of options
granted  under  the  Plan,   312,975  shares  were  issuable  upon  exercise  of
outstanding  options under the Plan and 80,329 shares were  available for future
grants of options under the Plan. The last sale price of a share of Common Stock
on the Nasdaq SmallCap Market on March 10, 2000 was $6.563.

     Terms of Options.  The  Compensation  Committee in its discretion may issue
stock  options  which  qualify as incentive  stock options under the Code (to be
issued to employees only) or non-statutory stock options (which may be issued to
any eligible employee or consultant). Under the Plan, the Compensation Committee
will determine the time or times when each stock option becomes exercisable, the
period within which it remains  exercisable  and the applicable  exercise price.
However,  no incentive stock option may be exercised more than 10 years after it
is granted (5 years,  in the case of any incentive  stock option  granted to the
owner of 10% or more of the voting power of the Common Stock (a "10%  Holder")),
and the exercise  price of any  incentive  stock option may not be less than the
fair  market  value of the Common  Stock on the date of grant  (110% of the fair
market value in the case of any 10% Holder).

     Payment for shares  purchased  upon  exercise of any option  under the Plan
must be made in full when the option is exercised,  with such payment to be made
by cash,  check or the  surrender of shares of Common Stock having a fair market
value equal to the  aggregate  exercise  price of the options  being  exercised.
Except for certain permitted  transfers of nonstatutory stock options to certain
immediate  family  members,  no option may be transferred  except by will or the
laws of descent and  discretion  and  distribution  and,  during the  optionee's
lifetime,  the option may be exercised  only by the  optionee.  If an optionee's
employment or association with the Company terminates for any reason,  including
without  limitation  by reason of voluntary  severance,  involuntary  severance,
death or retirement,  any option  exercisable on the date of termination  may be
exercised by the optionee  but only for the period  specified in the  applicable
option agreement.

     Notwithstanding  any other provision of the Plan, the aggregate fair market
value  (determined  as of the date of grant) of the shares with respect to which
incentive  stock options are  exercisable  for the first time by any employee in
any  calendar  year may not exceed  $100,000  (with any  excess  portion of such
options to be treated as non-statutory stock options).

                                      12
<PAGE>

     Formula  Grants.  Members  of the  Compensation  Committee  may be  granted
options  under the Plan  only by  Formula  Grants  thereunder.  Options  granted
pursuant to a Formula Grant are  non-statutory  stock  options.  Formula  Grants
require no action by the  Compensation  Committee or the Board of Directors  and
occur as follows:


     1. Each  individual who is elected to the Board of Directors  after January
1, 2000 but during the term of the Plan and who was never before a member of the
Board and is not, immediately prior to such election,  an officer or employee of
the  Company,  shall be granted an option to  purchase  10,000  shares of Common
Stock.  These Formula Grants become  exercisable in three (3) equal installments
on each of the next three (3) annual meetings of the stockholders of the Company
(or special meetings in lieu of such annual  meetings)  provided the director is
an Outside  Director  on the day  immediately  prior to such date and has been a
director of the Company  since the last annual  meeting of  shareholders  of the
Company  (or  special  meeting  in lieu  thereof).  In the event that an Outside
Director was not elected at an annual meeting of  stockholders of the Company or
at a special meeting in lieu thereof, the Formula Grant shall become exercisable
for the first  installment  of vested shares on the date of the  Company's  next
annual meeting of stockholders of the Company or special meeting in lieu thereof
following  the first (1st)  anniversary  of the date of such Outside  Director's
election or appointment to the Board and thereafter for additional  installments
on the next two following annual meetings of the stockholders of the Company (or
special meetings in lieu thereof),  provided the director is an Outside Director
on the day immediately prior to such date and has been a director of the Company
since the last annual meeting of shareholders of the Company (or special meeting
in lieu thereof). As of December 31, 1999, formula options under the Amended and
Restated  1991 Stock  Option Plan (i.e.,  options to  purchase  4,000  shares of
Common Stock under the old formula  option  provisions) to purchase an aggregate
of 10,800  shares of Common  Stock had been granted to directors of the Company,
and no new formula  options  under the Second  Amended and  Restated  1991 Stock
Option Plan had been granted to directors of the Company.

     2.  Commencing  on May 15,  2000,  each  Outside  Director  (including  any
incumbent  Outside  Directors)  who, on any  February  15, May 15,  August 15 or
November  15 of any year after the first  anniversary  of the date on which such
Outside  Director was first elected to the Board of Directors,  is a director of
the Company,  shall be granted an option to purchase 500 shares of Common Stock.
Each of these  options  are  exercisable  immediately  upon their  grant.  As of
December 31, 1999,  under the old Quarterly  Formula  Grants  (i.e.,  options to
purchase 150 shares of Common Stock granted  quarterly),  options to purchase an
aggregate of 10,800  shares had been granted to Richard A.  Sandberg,  Thomas E.
Tierney,  David P. Fialkow and Elizabeth B. Connell under this  provision of the
Plan.

     Non-statutory  options granted  pursuant to Formula Grants have an exercise
price  equal to the fair  market  value of the Common  Stock on the date of such
Formula Grant and have a term of ten years.  Options granted pursuant to Formula
Grants to outside  directors who are not reelected or are removed from the Board
of  Directors  are  exercisable  thereafter  only  until the  earlier of (i) the
expiration  date  specified  for such  options in the  applicable  option  award
agreement or (ii) ninety days after such director's term of service expires,  in
the case of non-reelection, or is terminated, in the case of removal.

     Summary  of  Tax  Consequences.  The  following  is  a  brief  and  general
discussion of the federal income tax rules  applicable to stock options  granted
under the Plan.  With respect to an incentive  stock  option,  an employee  will
generally not be taxed at the time of grant or exercise, although exercise of an
incentive  option will give rise to an item of tax preference that may result in
an alternative  minimum tax, and the Company will not be entitled to a deduction
for  federal  income tax  purposes  as a result of the grant or  exercise of the
option.  If an optionee holds the shares  acquired upon exercise of an incentive
stock  option  until at least one year after  issuance  and two years  after the
option grant, he or she will have long-term  capital gain, or loss, based on the
difference between the amount realized on the sale or disposition and his or her
option  price,  and the Company  will not be entitled to a deduction at the time
the  options  sells  such  option  shares.  If  these  holding  periods  are not
satisfied,  then upon  disposition  of the shares the  optionee  will  recognize
ordinary income equal, in general, to the excess of the fair market value of the
shares at time of exercise over the option  price,  plus capital gain in respect
of any  additional  appreciation,  and the Company will  generally be allowed an
income tax  deduction in the same amount at the time of such  disposition.  With
respect to a non-statutory  stock option under the Plan, an optionee will not be
taxed at the time of grant;  upon  exercise,  he or she will  generally  realize
compensation  income  to the  extent  the then  fair  market  value of the stock
exceeds the option price. The Company will generally have a tax deduction to the
extent that, and at the time that, an optionee realizes compensation income with
respect to an option.

                                       13
<PAGE>

     Termination.  The Plan will terminate on March 29, 2010.

     Options  Granted under the Plan.  As of December 31, 1999,  options for the
purchase of a total of 312,975 shares of Common Stock were outstanding under the
Plan (of which 83,069 were  exercisable  as of such date),  and options or other
awards to purchase an  additional  80,329  shares  remained  available for grant
under the Plan.  The following  table sets forth  information as of December 31,
1999 with respect to stock options  which have been received  since the Plan was
adopted by the Company by (i) each of the  Company's  Chief  Executive  Officer,
former Chief Executive  Officer and the other  executive  officer of the Company
named in the Summary  Compensation  Table,  (ii) all  executive  officers of the
Company  as a  group,  (iii)  each of the  directors  of the  Company,  (iv) all
directors  of the Company,  other than those who are  executive  officers,  as a
group, and (v) all employees of the Company,  excluding executive officers, as a
group.


                   Option Grants under 1991 Stock Option Plan
<TABLE>
<CAPTION>
<S>                                                             <C>
                                                               Option
Name                                                          (shares)(1)
- ----------------                                              -----------
John G. Simon...............................................     12,992
Daniel Muscatello...........................................    108,189
Richard A. Sandberg.........................................     12,576
Thomas E. Tierney...........................................     12,576
Elizabeth B. Connell, M.D...................................      7,700
E. Kevin Hrusovsky..........................................       --
Domenic C. Micale...........................................     19,800
All executive officers as a group...........................    127,989
All directors of the Company,
 excluding executive officers as a group....................     45,844
All employees of the Company
 excluding executive officers as a group....................    385,838
</TABLE>

- --------------------------

     (1) Excludes options issued and subsequently terminated.


     The Board of  Directors  believes  that  approval of the  Company's  Second
Amended and  Restated  1991 Stock  Option Plan is in the best  interests  of all
stockholders  and recommends  that the  stockholders  vote "FOR" Proposal 2. The
enclosed  proxy  will be so  voted  unless a  contrary  vote is  indicated.  The
affirmative  vote of the  holders  of a majority  of the shares of Common  Stock
voted on the issue at the Meeting,  in person or by proxy, is required to ratify
the adoption of the Second Amended and Restated Plan by the Board of Directors.

     If the  proposal  to adopt the  Second  Amended  and  Restated  Plan is not
approved at the Meeting,  the  Company's  Amended and Restated 1991 Stock Option
Plan as previously adopted by the Board of Directors of the Company and approved
by the stockholders of the Company will remain in full force and effect.


                                       14
<PAGE>


                                   PROPOSAL 3

             RATIFICATION OF APPOINTMENT OF INDEPENDENT ACCOUNTANTS

     PricewaterhouseCoopers LLP, independent accountants,  have been independent
accountants  of the Company since 1991.  The Board of Directors has  recommended
that the stockholders ratify the reappointment of PricewaterhouseCoopers  LLP as
the Company's independent accountants for the current year.

     A representative of PricewaterhouseCoopers LLP is expected to be present at
the Meeting and will be afforded an  opportunity  to make a  statement,  if such
representative desires to do so, and will be available to answer any appropriate
questions.

     The Board of  Directors  recommends  that the  stockholders  vote "FOR" the
proposal  to ratify  the  appointment  of  PricewaterhouseCoopers  LLP,  and the
enclosed  proxy  will be so  voted  unless a  contrary  vote is  indicated.  The
affirmative  vote of the  holders  of a majority  of the shares of Common  Stock
entitled  to  vote  on  this  proposal  is  required  for  ratification  of  the
appointment  of  PricewaterhouseCoopers  LLP.  In the event the  appointment  of
PricewaterhouseCoopers LLP should not be ratified by the stockholders, the Board
of  Directors  will make  another  appointment  to be  effective at the earliest
possible time.


                              STOCKHOLDER PROPOSALS

     The Board will make provision for presentation of proposals by stockholders
at the 2001 Annual Meeting of Stockholders  (or special meeting in lieu thereof)
provided such proposals are submitted by eligible stockholders who have complied
with the relevant  regulations of the Securities and Exchange  Commission.  Such
proposals  must be received by the Company no later than December 11, 2000 to be
considered  for  inclusion to the  Company's  proxy  materials  relating to that
meeting.

             SECTION 16(a) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE

     Under the securities  laws of the United States,  the Company's  directors,
its executive (and certain other) officers and any persons holding more than ten
percent of the Common Stock are required to report their ownership of the Common
Stock  and  any  changes  in  that  ownership  to the  Securities  and  Exchange
Commission.  Specific due dates for these reports have been  established and the
Company is  required  to report in this Proxy  Statement  any failure to file by
these dates during  1999.  To the best  knowledge  of the Company,  all of these
filing requirements were satisfied by the Company's directors,  officers and ten
percent  holders  with the  following  exceptions.  Messrs.  Simon,  Muscatello,
Micale, Sandberg,  Fialkow, Tierney and Dr. Connell made late Form 5 filings. In
making these statements,  the Company has relied upon the written representation
of its directors, officers and its ten percent holders and copies of the reports
that they have filed with Securities and Exchange Commission.

                                     GENERAL

     The Board of  Directors  of the Company  knows of no matter  other than the
foregoing to be brought  before the Meeting.  However,  the enclosed proxy gives
discretionary authority in the event any additional matters should be presented.

     THE COMPANY  WILL  PROVIDE  FREE OF CHARGE TO ANY  STOCKHOLDER  FROM WHOM A
PROXY IS SOLICITED  PURSUANT TO THIS PROXY STATEMENT,  UPON WRITTEN REQUEST FROM
SUCH  STOCKHOLDER,  A  COPY  OF THE  COMPANY'S  ANNUAL  REPORT  FILED  WITH  THE
SECURITIES  AND EXCHANGE  COMMISSION ON FORM 10-K FOR THE COMPANY'S  FISCAL YEAR
ENDED  DECEMBER  31, 1999.  REQUESTS  FOR SUCH REPORT  SHOULD BE DIRECTED TO THE
MANAGER OF INVESTOR RELATIONS AT UROMED  CORPORATION,  1400 PROVIDENCE  HIGHWAY,
BUILDING 2, NORWOOD, MASSACHUSETTS, 02062.

     The Company  expects to hold its next  stockholder  meeting on May 18, 2001
and proxy  materials in  connection  with that meeting are expected to be mailed
approximately 30 days prior to the meeting.



John G. Simon
Chairman of the Board
                                     15

<PAGE>


                               UroMed Corporation
    Proxy for the Special Meeting of Stockholders to be held on May 12, 2000
           THIS PROXY IS SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS

     The  undersigned,  revoking all prior  proxies,  hereby  appoint(s)  Daniel
Muscatello  and  Domenic  C.  Micale,  and  each of  them,  with  full  power of
substitution,  as proxies to represent and vote as designated herein, all shares
of stock of UroMed  Corporation  which the undersigned would be entitled to vote
if personally  present at the Special  Meeting of Stockholders of the Company to
be held at Bingham Dana LLP, 150 Federal Street, Boston, Massachusetts on Friday
May 12, 2000 at 9:00 a.m., or any adjourned session thereof.

     In their  discretion,  the proxies are  authorized  to vote upon such other
matters as may properly come before the meeting or any adjournment thereof.

     This proxy,  when properly  executed,  will be voted in the manner directed
herein by the undersigned stockholder. IF NO DIRECTION IS GIVEN, THIS PROXY WILL
BE  VOTED  FOR  PROPOSALS  1,  2 AND 3 OF THE  BOARD  OF  DIRECTORS,  AND IN THE
DISCRETION OF THE BOARD OF DIRECTORS ON SUCH OTHER BUSINESS AS MAY PROPERLY COME
BEFORE THE  MEETING.  Attendance  of the  undersigned  at the  meeting or at any
adjournment  thereof  will  not be  deemed  to  revoke  this  proxy  unless  the
undersigned shall vote in person at such meeting or revoke this proxy in writing
before it is exercised.

                PLEASE VOTE, DATE AND SIGN ON REVERSE AND RETURN
                        PROMPTLY IN THE ENCLOSED ENVELOPE

     Please sign this Proxy  exactly as your  name(s)  appear(s)  on the reverse
side  hereof.  Joint  owners  should each sign  personally.  Trustees  and other
fiduciaries should indicate the capacity in which they sign, and where more than
one name appears, a majority must sign. If a corporation,  this signature should
be that of an authorized officer who should state his or her title.

    HAS YOUR ADDRESS CHANGED?                        DO YOU HAVE ANY COMMENTS?


   -------------------------                         ------------------------




                                       16
<PAGE>

[X] PLEASE MARK VOTES AS IN THIS EXAMPLE

     1. To elect the following  persons as Class III Directors (except as marked
below):
                              John G. Simon
                              Richard A. Sandberg
<TABLE>
<CAPTION>
<S>                            <C>           <C>
FOR ALL NOMINEES               WITHHOLD      FOR ALL EXCEPT
     [ ]                          [ ]             [ ]
</TABLE>
     NOTE: If you do not wish your shares voted "For" a particular nominee, mark
the "For All Except" box and strike a line through the name of the nominee. Your
shares will be voted for the remaining nominee.

     2) A proposal to adopt the Company's Second Amended and Restated 1991 Stock
Option Plan.
<TABLE>
<CAPTION>
     <S>                         <C>             <C>
     FOR                         AGAINST         ABSTAIN
     [ ]                           [ ]             [ ]
</TABLE>
     3. To ratify the appointment of  PricewaterhouseCoopers  LLP as independent
accountants of the Company for the 2000 fiscal year.
<TABLE>
<CAPTION>
     <S>                         <C>             <C>
     FOR                         AGAINST         ABSTAIN
     [ ]                           [ ]             [ ]
</TABLE>
     4. To transact such other  business as may properly come before the meeting
or at any adjourned session of the meeting.

    UROMED CORPORATION

    CONTROL NUMBER:

    RECORD DATE SHARES:

    Please be sure to sign and date this Proxy.

    Date  ________________

    Stockholder sign here  -------------------------
    Co-owner sign here     -------------------------

    Mark box at right if an address or comment has been noted on the reverse
    side of this card.  [ ]

DETACH CARD                                                      DETACH CARD


    UROMED CORPORATION

Dear Stockholder:

     Please take note of the  important  information  enclosed  with this Proxy.
There are a number of issues  related to the  management  and operations of your
Company that require your immediate attention and approval.  These are discussed
in detail in the enclosed proxy materials.

     Your vote counts, and you are strongly encouraged to exercise your right to
vote your shares.

     Please mark the boxes on this proxy card to  indicate  how your shares will
be voted,  then sign the card,  detach it and return it in the enclosed  postage
paid envelope.

     Your vote must be received prior to the Special  Meeting of Stockholders of
the Company on Friday, May 12, 2000.

     Thank you in advance for your prompt consideration of these matters.

Sincerely,

UroMed Corporation

                                       17
<PAGE>



                                   Appendix 1


                             As Amended and Restated
                              as of March 29, 2000


                               UROMED CORPORATION
               SECOND AMENDED AND RESTATED 1991 STOCK OPTION PLAN


     1.  Definitions.  As used in this Second  Amended and  Restated  1991 Stock
Option Plan of UroMed Corporation,  the following terms shall have the following
meanings:

     1.1. Awarded Option means all Options other than Formula Options.

     1.2. Board means the Company's Board of Directors.

     1.3. Code means the federal Internal Revenue Code of 1986, as amended.

     1.4. Committee means the Compensation  Committee of the Board, or any other
committee appointed by the Board, responsible for the administration of the Plan
as provided in section 5 of the Plan.

     1.5. Company means UroMed Corporation, a Massachusetts corporation.

     1.6. Employment  Agreement means an agreement,  if any, between the Company
and an Optionee, setting forth, inter alia, conditions and restrictions upon the
transfer of shares of Stock.

     1.7.  Fair  Market  Value means on any date (i) if the Stock is traded on a
stock exchange or on the Nasdaq SmallCap  Market,  the closing price on the date
in question or, if no trades were  reported on such date,  the closing  price on
the most recent trading day preceding such date on which a trade  occurred,  and
(ii) if the Stock is not traded on a stock  exchange  or on the Nasdaq  National
Market,  the  value  of a share  of  Stock  on such  date as  determined  by the
Committee.

     1.8.  First  Amended  and  Restated  Plan means the  Company's  Amended and
Restated 1991 Stock Option Plan effective August 15, 1995.

     1.9. Formula Grant means a grant of Options pursuant to Section 8.1.

     1.10. Formula Grant Date shall have the meaning specified in Section 8.1

     1.11. Formula Options means Options granted pursuant to Section 8.

     1.12.  Grant  Date  means  the date as of which an Option  is  granted,  as
determined under Section 7.1.

     1.13.  Incentive Option means an Option which by its terms is to be treated
as an "incentive stock option" within the meaning of Section 422 of the Code.

     1.14. Nonstatutory Option means any Option that is not an Incentive Option.

     1.15.  Option means an Awarded Option or Formula Option to purchase  shares
of Stock granted under the Plan.

     1.16.  Option  Agreement  means an  agreement  between  the  Company and an
Optionee, setting forth the terms and conditions of an Option.

     1.17. Option Price means the price paid by an Optionee for a share of Stock
upon exercise of an Option.

     1.18. Optionee means a person eligible to receive an Option, as provided in
Section 6, to whom an Option shall have been granted under the Plan.

     1.19.  Outside  Director  shall  mean a member  of the  Board who is not an
officer or an employee of the Company or any Subsidiary.

                                       18
<PAGE>

     1.20. Plan means this Second Amended and Restated 1991 Stock Option Plan of
the Company, as amended from time to time.

     1.21. Stock means Common Stock, no par value, of the Company.

     1.22.  Subsidiary means any corporation  which qualifies as a subsidiary of
the Company under the definition of "subsidiary  corporation"  in Section 424(f)
of the Code.

     1.23.  Ten Percent  Owner means a person who owns,  or is deemed within the
meaning of Section  422(b)(6) of the Code to own, stock possessing more than 10%
of the total  combined  voting  power of all classes of stock of the Company (or
its parent or subsidiary corporations).  Whether a person is a Ten Percent Owner
shall be  determined  with  respect to each Option  based on the facts  existing
immediately prior to the Grant Date of such Option.

     1.24.  Termination of Service with respect to any Outside Director shall be
deemed to have  occurred  at the close of business on the last day on which such
Outside Director is a director of the Company.

     1.25.  Vested Shares, as of any date, means those shares of Stock available
at that date for  purchase by exercise of a Formula  Option  pursuant to Section
8.4.

     1.26.  Vesting  Year for any  portion  of any  Incentive  Option  means the
calendar year in which that portion of the Option first becomes exercisable.

     2.  Purpose.  This Plan is  intended  to  encourage  ownership  of Stock by
employees  and  outside  directors  of and  consultants  to the  Company and its
Subsidiaries  and to  provide  additional  incentives  for them to  promote  the
success of the Company's business. The Plan is intended to be an incentive stock
option  plan  within the  meaning of Section 422 of the Code but not all Options
granted hereunder are required to be Incentive Options.

     3. Term of the Plan.  Options may be granted  hereunder  at any time in the
period  commencing on the approval of the Plan by the Board and ending not later
than ten (10) years  after the  earlier of  adoption of the Plan by the Board or
approval of the Plan by shareholders.

     4.  Stock  Subject  to the Plan.  At no time  shall the number of shares of
Stock then outstanding which are attributable to the exercise of Options granted
under the  Plan,  plus the  number of shares  then  issuable  upon  exercise  of
outstanding  Options  granted under the Plan,  exceed 890,000  shares,  subject,
however,  to the provisions of Section 13 of the Plan.  Shares to be issued upon
the  exercise of Options  granted  under the Plan may be either  authorized  but
unissued  shares or shares  held by the Company in its  treasury.  If any Option
expires or terminates  for any reason without having been exercised in full, the
shares not purchased  thereunder shall again be available for Options thereafter
to be granted.

     5.  Administration.  The Plan shall be  administered  by the Committee.  No
member of the Committee  shall receive a grant of an Option other than a Formula
Option during service on the Committee and,  except for Options granted prior to
December 31, 1993 and for Formula Options, no member of the Committee shall have
received a grant of an Option during the one-year period preceding such service.
Subject  to the  provisions  of the Plan,  the  Committee  shall  have  complete
authority,  in its  discretion,  to make or to select  the  manner of making the
following  determinations  with  respect  to each  Option,  other than a Formula
Option, to be granted by the Company:  (a) the employee or consultant to receive
the  Option;  (b)  whether  the Option (if  granted to an  employee)  will be an
Incentive  Option or Nonstatutory  Option;  (c) the time of granting the Option;
(d) the number of shares  subject to the Option;  (e) the Option Price;  (f) the
Option  period;  and (g) the  Option  exercise  date or dates.  In  making  such
determinations,  the  Committee may take into account the nature of the services
rendered  by  the  respective  employees  and  consultants,  their  present  and
potential contributions to the success of the Company and its Subsidiaries,  and
such other  factors as the  Committee  in its  discretion  shall deem  relevant.
Subject to the  provisions of the Plan,  the Committee  shall also have complete
authority to  interpret  the Plan,  to  prescribe,  amend and rescind  rules and
regulations  relating  to it,  to  determine  the terms  and  provisions  of the
respective  Option  Agreements  (which  need not be  identical)  other  than for
Formula Options, and to make all other determinations necessary or advisable for
the  administration  of the Plan. The Committee's  determinations on the matters
referred to in this Section 5 shall be conclusive.

                                       19
<PAGE>

     6.  Eligibility.  An  Option  shall  be  granted  only  to an  employee  or
consultant  of one or more  of the  Company  or any  Subsidiary  or any  Outside
Director. As provided in Section 5, no member of the Committee shall be eligible
to receive an Option other than a Formula Option.

     7. Awarded Options.

     7.1. Time of Granting Options. The granting of an Awarded Option shall take
place at the time  specified  in the  Option  Agreement.  Only if  expressly  so
provided in the Option  Agreement,  shall the Grant Date be the date on which an
Option  Agreement shall have been duly executed and delivered by the Company and
the Optionee.

     7.2.  Option  Price.  The Option Price under each  Awarded  Option shall be
determined by the Committee but, in the case of any Incentive  Option,  shall be
not less than 100% of the Fair Market  Value of Stock on the Grant Date,  or not
less  than  110% of the Fair  Market  Value of  Stock on the  Grant  Date if the
Optionee is a Ten Percent Owner. The Option Price under each Nonstatutory Option
shall not be so limited solely by reason of this Section 7.2.

     7.3.  Option Period.  No Incentive  Option may be exercised  later than the
tenth (10th)  anniversary  of the Grant Date, but in any case not later than the
fifth  (5th)  anniversary  of the Grant Date,  if the  Optionee is a Ten Percent
Owner. The Option period under each Nonstatutory  Option shall not be so limited
solely by reason of this Section 7. An Awarded Option may become  exercisable in
such installments, cumulative or non-cumulative, as the Committee may determine.
In the case of an Awarded Option not otherwise immediately  exercisable in full,
the Committee may accelerate the  exercisability of such Awarded Option in whole
or in part at any time,  provided the acceleration of the  exercisability of any
Incentive  Option would not cause the Awarded  Option to fail to comply with the
provisions of Section 422 of the Code.

     7.4. Limit on Incentive Option Characterization.  No Incentive Option shall
be considered an Incentive  Option to the extent  pursuant to its terms it would
permit the  Optionee  to purchase  for the first time in any Vesting  Year under
that  Incentive  Option  more than the number of shares of Stock  calculated  by
dividing  the  current  limit by the Option  Price.  The  current  limit for any
Optionee for any Vesting Year shall be $100,000  minus the aggregate Fair Market
Value at the date of  grant of the  number  of  shares  of Stock  available  for
purchase  for the first time in the  Vesting  Year  under  each other  Incentive
Option  granted to the Optionee  under the Plan after December 31, 1986 and each
other  incentive  stock option  granted to the Optionee  after December 31, 1986
under any other  incentive  stock  option  plan of the  Company  (and any parent
corporation and Subsidiaries).

     7.5. Exercise of Option. An Awarded Option may be exercised by the Optionee
giving  written  notice,  in the manner  provided in Section 17,  specifying the
number  of  shares  with  respect  to which the  Awarded  Option  is then  being
exercised.  The notice shall be  accompanied  by payment in the form of cash, or
certified  or bank check  payable to the order of the Company in an amount equal
to the option price of the shares to be purchased plus any required  withholding
tax as provided in Section 11; provided,  however,  that after the date that any
shares  of Stock  have been  registered  under the  Securities  Act of 1933,  as
amended  (the  "Securities  Act"),  for sale to the public,  such payment may be
made,  at the election of the  Optionee or other  person or persons  entitled to
exercise the Awarded Option:  (1) in cash or certified or bank check as provided
above;  (2) in the form of Stock owned by the Optionee (based on the Fair Market
Value of the Stock on the day the  Awarded  Option is  exercised)  evidenced  by
negotiable stock certificates registered in the sole name of the Optionee or the
names of the Optionee and spouse; or (3) in any combination of the consideration
referred  to in (1) and (2)  above.  Receipt by the  Company of such  notice and
payment  shall  constitute  the exercise of the Awarded  Option.  Within 30 days
thereafter  but subject to the  remaining  provisions  of the Plan,  the Company
shall  deliver  or  cause  to be  delivered  to  the  Optionee  or his  agent  a
certificate or certificates for the number of shares then being purchased.  Such
shares shall be fully paid and nonassessable.

     7.6.  Termination  of  Association  with  the  Company.  If the  Optionee's
employment or association with the Company is terminated, whether voluntarily or
otherwise,  the Awarded Option,  to the extent the Awarded Option is exercisable
on the date of  termination,  may be  exercised by the Optionee but only for the
period  specified in the Option  Agreement.  Military or sick leave shall not be
deemed a termination of employment,  provided that it does not exceed the longer
of 90 days or the period during which the absent Optionee's reemployment rights,
if any, are guaranteed by statute or by contract.

                                       20
<PAGE>

     8. Formula Options.

     8.1.  Directors  Elected For First Time. (a) Each individual who is elected
to the Board after  September  1, 1995 but during the term of the First  Amended
and Restated Plan,  and was never before a member of the Board,  and who is not,
immediately  prior to his or her  election  to the  Board,  either an officer or
employee  of the  Company  or any  Subsidiary,  whether  elected at an annual or
special  stockholders'  meeting or by action of the Board, shall be granted,  on
the date of such meeting or other appointment, a Nonstatutory Option to purchase
4,000 shares of Stock.

     (b) Each  individual who is elected to the Board of Directors after January
1, 2000 and  during the term of the Plan,  and was never  before a member of the
Board,  and who is not,  immediately  prior to his or her election to the Board,
either an officer or employee of the Company or any Subsidiary,  whether elected
at an annual or special  stockholders'  meeting or by action of the Board, shall
be granted, on the date of such meeting or other appointment (as used in or with
reference  to this  Section 8.1  with  respect to the  election  or  appointment
referred  to in  paragraph  (a) or (b) of this  Section  8.1, a  "Formula  Grant
Date"), a Nonstatutory Option to purchase 10,000 shares of Stock.

     8.2.  Quarterly  Formula  Grants.  Commencing  with  August  15,  1995  and
continuing  until  but  not  including  May  15,  2000,  each  Outside  Director
(including  any incumbent  Outside  Directors)  who, on any February 15, May 15,
August 15, or November 15 occurring  after the first  anniversary of the date on
which the Outside Director's was first elected to the Board (also referred to as
a "Formula  Grant  Date"),  is a  director  of the  Company,  shall be granted a
Nonstatutory  Option on such date to purchase 150 shares of Stock,  all of which
shall be considered Vested Shares at the time of grant.  Commencing with May 15,
2000, each such Outside Director shall be granted a Nonstatutory  Option on such
date to purchase 500 shares of Stock,  all of which shall be  considered  Vested
Shares at the time of grant.

     8.3. Terms of Formula  Options.  Each Formula Option granted to an Optionee
under  Section 8  shall have an exercise  price equal to 100% of the Fair Market
Value of the Stock on the  applicable  Formula Grant Date.  Each Formula  Option
granted under Section 8.1(a) hereof shall become  exercisable  for Vested Shares
in six (6) equal installments,  with the Formula Option becoming exercisable for
the first  installment of Vested Shares on the date of the Company's next annual
meeting of  stockholders  of the Company or special  meeting of  stockholders in
lieu of an annual  meeting,  as the case may be, and additional  installments of
Vested Shares shall become  exercisable on the day of each of the Company's next
five (5) annual meetings of  stockholders of the Company or special  meetings in
lieu of an annual  meeting,  in each case if the  Optionee  remains  an  Outside
Director of the Company on the day immediately preceding the applicable date and
has been a director for the previous  year.  Each Formula  Option  granted under
Section  8.1(b) hereof shall become  exercisable  for Vested Shares in three (3)
equal installments,  with the Formula Option becoming  exercisable for the first
installment of Vested Shares on the date of the Company's next annual meeting of
stockholders  of the Company or special  meeting of  stockholders  in lieu of an
annual meeting, as the case may be, following the annual meeting of stockholders
of the Company or special meeting in lieu thereof at which the Outside  Director
was  elected,  and  additional   installments  of  Vested  Shares  shall  become
exercisable on the day of each of the Company's next two (2) annual  meetings of
stockholders of the Company or special meetings in lieu thereof, in each case if
the Optionee  remains an Outside  Director of the Company on the day immediately
preceding the  applicable  date and was a director for the previous year. In the
event  that an  Outside  Director  was  not  elected  at an  annual  meeting  of
stockholders of the Company or at a special meeting in lieu thereof, the Formula
Option shall become  exercisable  for the first  installment of Vested Shares on
the date of the Company's next annual meeting of  stockholders of the Company or
special  meeting in lieu thereof  following the first (1st)  anniversary  of the
date of such  Outside  Director's  election  or  appointment  to the  Board  and
thereafter as described for additional  installments in the preceding  sentence.
Each Formula Option  granted under Section 8.2 shall be  exercisable  for Vested
Shares on the applicable  Formula Grant Date. No Formula Option granted pursuant
to this Section 8 is intended to qualify as an incentive stock option within the
meaning of Section 422 of the Code.  The Formula  Grants  shall be  evidenced by
Option  Agreements.  The Option Agreements shall contain  provisions  consistent
with this Section 8, and the Option Agreements shall contain identical terms and
conditions,  except (i) as otherwise required by this Section 8 and (ii) for any
restrictions imposed with respect to Formula Grants granted prior to the receipt
of any  stockholders'  approval  required  pursuant to Rule  16b-3(b)  under the
Securities Exchange Act of 1934, as amended.

                                       21
<PAGE>

     8.4.  Option  Period.  The Option  Period for any  Formula  Option  granted
pursuant to this Section 8 shall be ten years from the date of grant. No Formula
Option  may be  exercised  at any time  unless the  Formula  Option is valid and
outstanding as provided in this Section 8 and represent Vested Shares.

     8.5.  Exercisability.  A Formula Option may be exercised,  so long as it is
valid and  outstanding,  from time to time in part or as a whole for that number
of Vested Shares then subject to such Formula Option.

     8.6. Method of Exercise.  A Formula Option may be exercised by the Optionee
giving  written  notice,  in the manner  provided in Section 17,  specifying the
number  of  shares  with  respect  to which the  Formula  Option  is then  being
exercised.  The notice shall be  accompanied  by payment in the form of cash, or
certified or bank check payable to the order of the Company,  in an amount equal
to the Option Price of the shares to be purchased plus any required  withholding
tax as provided in Section 11; provided,  however,  that after the date that any
shares of Stock have been  registered  under the Securities Act, for sale to the
public,  such  payment may be made,  at the  election  of the  Optionee or other
person or persons  entitled  to  exercise  the  Formula  Option:  (1) in cash or
certified or bank check as provided above; (2) in the form of Stock owned by the
Optionee  (based on the Fair  Market  Value of the Stock on the day the  Formula
Option is exercised)  evidenced by negotiable stock  certificates  registered in
the sole name of the Optionee or the names of the Optionee and spouse; or (3) in
any combination of the consideration  referred to in (1) and (2) above.  Receipt
by the Company of such notice and payment shall  constitute  the exercise of the
Formula  Option.  Within  30  days  thereafter  but  subject  to  the  remaining
provisions  of the Plan,  the Company  shall deliver or cause to be delivered to
the Optionee or his agent a certificate or certificates for the number of shares
then  being   purchased.   Such   shares  of  Stock  shall  be  fully  paid  and
nonassessable.

     8.7.  Termination of Service.  After an Outside  Director's  Termination of
Service a Formula  Option shall remain  exercisable,  subject to  adjustment  as
provided in Section 13, only with  respect to the number of shares of Stock that
the  Optionee  could  have  acquired  by  an  exercise  of  the  Formula  Option
immediately  prior to the  Termination  of  Service,  but in no event  shall any
Formula Option be  exercisable  after the earlier to occur of (i) the expiration
date of the Formula Option as specified in the applicable Option  Agreement,  or
(ii) ninety (90) days after the Termination of Service.

     9. Restrictions on Issue of Shares.

     (a)  Notwithstanding  any other  provision of the Plan, if, at any time, in
the reasonable opinion of the Company the issuance of shares of Stock covered by
the exercise of any Option may  constitute a violation of law,  then the Company
may delay such issuance and the delivery of a certificate  for such shares until
(i) approval  shall have been obtained from such  governmental  agencies,  other
than the  Securities  and  Exchange  Commission,  as may be  required  under any
applicable  law, rule, or  regulation;  and (ii) in the case where such issuance
would  constitute a violation of a law  administered  by or a regulation  of the
Securities and Exchange  Commission,  one of the following conditions shall have
been satisfied:

     (1) the shares with respect to which such Option has been  exercised are at
the time of the issue of such shares effectively registered under the Securities
Act; or

     (2) a no-action letter in form and substance reasonably satisfactory to the
Company with respect to the issuance of such shares shall have been  obtained by
the Company from the Securities and Exchange Commission.

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     The Company shall make all reasonable efforts to bring about the occurrence
of said events.

     (b) Each  certificate  representing  shares  issued upon the exercise of an
Option  will  bear  restrictive  legends  which  may  refer to this  Plan and to
applicable restrictions under the Employment Agreement.

     10. Purchase for Investment; Subsequent Registration.

     (a) Unless the shares to be issued upon exercise of an Option granted under
the Plan have been effectively  registered under the Securities Act, the Company
shall be under no  obligation  to issue any shares  covered by any Option unless
the person who exercises such Option,  in whole or in part, shall give a written
representation to the Company which is satisfactory in form and substance to its
counsel  and upon  which the  Company  may  reasonably  rely,  that he or she is
acquiring  the  shares  issued  pursuant  to such  exercise  of the Option as an
investment  and  not  with a view  to,  or for  sale  in  connection  with,  the
distribution of any such shares.

     (b) Each  share of Stock  issued  pursuant  to the  exercise  of an  Option
granted   pursuant  to  this  Plan  may  bear  a  reference  to  the  investment
representation  made in accordance  with this Section 10 and to the fact that no
registration   statement  has  been  filed  with  the  Securities  and  Exchange
Commission in respect to said Stock.

     (c) If the Company  shall deem it necessary or desirable to register  under
the Securities Act or other applicable statutes any shares of Stock with respect
to which an Option  shall have been  granted,  or to qualify any such shares for
exemption from the Securities Act or other applicable statutes, then the Company
shall take such action at its own  expense.  The  Company may require  from each
Option holder,  or each holder of shares of Stock acquired pursuant to the Plan,
such information in writing for use in any registration  statement,  prospectus,
preliminary  prospectus or offering circular as is reasonably necessary for such
purpose and may require reasonable indemnity to the Company and its officers and
directors from such holder against all losses,  claims,  damage and  liabilities
arising from such use of the  information  so furnished and caused by any untrue
statement  of any  material  fact  therein or caused by the  omission to state a
material fact required to be stated  therein or necessary to make the statements
therein not misleading in the light of the  circumstances  under which they were
made.

     11.  Withholding;  Notice of  Disposition  of Stock Prior to  Expiration of
Specified Holding Period.

     (a) Whenever  shares are to be issued in  satisfaction of an Option granted
hereunder,  the Company shall have the right to require the Optionee to remit to
the  Company an amount  sufficient  to satisfy  federal,  state,  local or other
withholding  tax  requirements  if and to the extent required by law (whether so
required to secure for the  Company an  otherwise  available  tax  deduction  or
otherwise)  prior to the delivery of any  certificate or  certificates  for such
shares.

     (b) The  Company  may  require as a  condition  to the  issuance  of shares
covered by any  Incentive  Option that the party  exercising  such Option give a
written  representation  to the  Company  which  is  satisfactory  in  form  and
substance to its counsel and upon which the Company may reasonably rely, that he
or she will report to the Company any  disposition  of such shares  prior to the
expiration of the holding periods specified by Section 422(a)(1) of the Code. If
and to the extent that the  realization of income in such a disposition  imposes
upon the Company federal, state, local or other withholding tax requirements, or
any such  withholding  is  required  to  secure  for the  Company  an  otherwise
available  tax  deduction,  the Company shall have the right to require that the
recipient   remit  to  the  Company  an  amount   sufficient  to  satisfy  those
requirements;  and the Company may  require as a  condition  to the  issuance of
shares covered by an Incentive Option that the party exercising such option give
a satisfactory written representation promising to make such a remittance.

     12.  Transferability  of  Options.   Options  shall  not  be  transferable,
otherwise  than by will or the  laws of  descent  and  distribution,  and may be
exercised  during  the  life of the  Optionee  only by the  Optionee;  provided,
however,  that this  Section  shall not bar a  transfer,  assignment  or sale of
Nonstatutory  Options by an Optionee to, or for the benefit of, such  Optionee's
parents,  siblings,  spouse and issue,  spouses of such Optionee's issue, or any
trust for the benefit of, or the legal  representative  of, any of the preceding
persons (each an "Immediate  Family Member"),  who shall take and be entitled to
exercise such  Nonstatutory  Options subject to all the limitations set forth in
this  Plan  and the  applicable  Option  Agreement.  Such  Nonstatutory  Options
transferred  to an  Immediate  Family  Member  during  the  lifetime  of such an
Optionee  shall be deemed to be owned and held by such  Optionee  rather than by
the  transferee,  unless  prior to any such  transfer,  assignment  or sale such
transferee  shall execute an instrument  of adherence to the  applicable  Option
Agreement,   and  such   instrument  of  adherence  is  in  form  and  substance
satisfactory to the Company.

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<PAGE>

     13.  Adjustment  of  Number  of  Option  Shares.  In the event of any stock
dividend payable in Stock or any split-up or contraction in the number of shares
of Stock  after the date of the Option  Agreement  and prior to the  exercise in
full of the Option,  the number of shares  subject to such Option  Agreement and
the  price  to  be  paid  for  each  share   subject  to  the  Option  shall  be
proportionately  adjusted.  In the  event of any  reclassification  or change of
outstanding  shares  of Stock or in case of any  consolidation  or merger of the
Company with or into  another  company or in case of any sale or  conveyance  to
another  company  or  entity  of the  property  of the  Company  as a  whole  or
substantially as a whole, shares of stock or other securities equivalent in kind
and value to those shares an Optionee  would have received if he or she had held
the full number of shares of Stock  subject to the Option  immediately  prior to
such reclassification, change, consolidation, merger, sale or conveyance and had
continued  to hold  those  shares  (together  with all other  shares,  stock and
securities  thereafter issued in respect thereof) to the time of the exercise of
the Option  shall  thereupon  be  subject to the  Option.  Upon  dissolution  or
liquidation of the Company, the Option shall terminate,  but the Optionee (if at
the time in the employ or retained as a consultant  of the Company or any of its
subsidiaries)  shall have the right,  immediately  prior to such  dissolution or
liquidation,  to exercise the Option to the extent not theretofore exercised. No
fraction of a share shall be purchasable or  deliverable  upon exercise,  but in
the event any adjustment hereunder of the number of shares covered by the Option
shall cause such number to include a fraction of a share,  such number of shares
shall be adjusted to the nearest smaller whole number of shares. In the event of
changes  in the  outstanding  Stock by reason of any stock  dividend,  split-up,
contraction,  reclassification,  or change of outstanding shares of Stock of the
nature  contemplated by this Section 13, the number of shares of Stock available
for the  purpose  of the Plan as  stated in  Section 4 shall be  correspondingly
adjusted.

     14. Reservation of Stock. The Company shall at all times during the term of
the Option reserve or otherwise keep available such number of shares of Stock as
will be  sufficient  to satisfy the  requirements  of the Plan and shall pay all
fees and expenses necessarily incurred by the Company in connection therewith.

     15.  Limitation of Rights in Stock; No Special  Employment or Other Rights.
The  Optionee  shall not be deemed for any  purpose to be a  stockholder  of the
Company with respect to any of the shares of Stock covered by an Option,  except
to the extent that the Option shall have been  exercised  with  respect  thereto
and, in addition, a certificate shall have been issued therefor and delivered to
the  Optionee or his agent.  Any Stock  issued  pursuant to the Option  shall be
subject  to all  restrictions  upon the  transfer  thereof  which  may be now or
hereafter  imposed  by the  Certificate  of  Incorporation,  the  By-laws of the
Company, and the Employment Agreement,  if any. Nothing contained in the Plan or
in any Option  shall  confer  upon any  Optionee  any right with  respect to the
continuation  of his or her  employment  with,  or  retention  as a  consultant,
director or advisor to, the Company (or any subsidiary), or interfere in any way
with the right of the Company (or any  subsidiary),  subject to the terms of any
separate  employment  or  consulting  agreement or provision of law or corporate
articles or by-laws to the contrary,  at any time to terminate such  employment,
consulting or advisory  relationship or to increase or decrease the compensation
of the  Optionee  from the  rate in  existence  at the  time of the  grant of an
Option.

     16.  Termination  and  Amendment  of the  Plan.  The  Board may at any time
terminate  the Plan or make  such  modifications  of the  Plan as it shall  deem
advisable.  No termination or amendment of the Plan may,  without the consent of
the Optionee to whom any Option shall  theretofore have been granted,  adversely
affect the rights of such Optionee under such Option. In considering  whether to
modify or amend the Plan, the Board shall consider whether such  modification or
amendment  requires the consent of the Company's  stockholders to continue to be
eligible for the  favorable  treatment  given to the Plan pursuant to Rule 16b-3
under the  Securities  Exchange Act of 1934, as amended,  and Section 422 of the
Code.  If such  consent  would be  required  for such  amendment,  and the Board
determines that the  continuation of such treatment under Rule 16b-3 and Section
422 (or any successor  provisions) is desirable for the Company,  then the Board
shall   seek  the   appropriate   stockholder   consent   for  such   amendment.
Notwithstanding  the  foregoing,  the  provisions  of Sections 1, 5, 6, and this
Section 16, insofar as they relate to Formula  Options,  and Section 8 shall not
be amended more often than once every six (6) months, other than to comport with
changes in the Code,  the Employee  Retirement  Income  Security Act of 1974, as
amended, or the rules and regulations thereunder.

     17. Notices and Other Communications.  All notices and other communications
required or  permitted  under the Plan shall be  effective  if in writing and if
delivered or sent by certified or registered mail,  return receipt requested (a)
if to the Optionee, at his or her residence address last filed with the Company,
and (b) if to the Company, at 1400 Providence Highway,  Building #2, Norwood, MA
02062,  Attention:  President  or to such  other  persons  or  addresses  as the
Optionee or the  Company may specify by a written  notice to the other from time
to time.

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