MEDICALOGIC/MEDSCAPE INC
SC 13D, EX-99.D, 2001-01-17
COMPUTER PROCESSING & DATA PREPARATION
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                                                            Page 21 of 92 Pages

                 PREFERRED STOCK AND WARRANT PURCHASE AGREEMENT

     THIS PREFERRED STOCK AND WARRANT PURCHASE  AGREEMENT is made as of December
22, 2000 by and among  MedicaLogic/Medscape,  Inc., an Oregon  corporation  (the
"Company"),  and the  Investors  listed  on  Schedule  A  attached  hereto  (the
"Investors").

     THE PARTIES HEREBY AGREE AS FOLLOWS:

     1. Purchase and Sale of Preferred Stock and Warrants.

          1.1 Sale and Issuance of Preferred Stock and Warrants.

               (a) The Company  shall adopt and file with the Secretary of State
          of Oregon on or before the Closing (as defined  below) the articles of
          amendment of its 1999 Restated Articles of  Incorporation,  as amended
          (the "Amended Articles") in the form attached hereto as Exhibit A.

               (b) Subject to the terms and  conditions of this  Agreement,  the
          Investors  severally and not jointly agree to purchase at the Closing,
          and the  Company  agrees  to sell and  issue to the  Investors  at the
          Closing,  (i)  that  number  of  shares  of  the  Company's  Series  1
          Convertible  Redeemable  Preferred  Stock  (the  "Series  1  Preferred
          Stock") set forth opposite each  Investor's  name on Schedule A hereto
          for the  purchase  price set  forth  thereon,  and (ii) a  warrant  to
          purchase  that  number of shares of the  Company's  Common  Stock (the
          "Common  Stock") set forth opposite each Investor's name on Schedule A
          hereto for the purchase price set forth thereon, such warrant to be in
          substantially  the form attached hereto as Exhibit B (the "Warrants").
          The rights, privileges and preferences of the Series 1 Preferred Stock
          will be as stated in the Amended Articles.

          1.2 Closings.  Unless this Agreement shall have terminated pursuant to
     Section 7, and subject to the  satisfaction or waiver of the conditions set
     forth in Sections 5 and 6, the  purchase and sale of the Series 1 Preferred
     Stock and Warrants  shall take place at one or more closings at the offices
     of Stoel Rives LLP, 900 SW Fifth Avenue,  Suite 2300,  Portland,  Oregon at
     such times and places as the Company and the Investors  mutually agree upon
     orally  or  in  writing  (which  times  and  places  are  designated  as  a
     "Closing").  At the  Closing  the Company  shall  deliver to each  Investor
     purchasing  Series 1 Preferred Stock and Warrants at such Closing  Warrants
     and  stock  certificates  representing  the  number  of  shares of Series 1
     Preferred  Stock and  Warrants  that such  Investor is  purchasing  against
     payment  of the  purchase  price  therefor  by  check or wire  transfer  in
     immediately available funds.

     2.  Representations  and  Warranties  of the  Company.  The Company  hereby
represents and warrants to the Investors that, except as set forth on a Schedule
of  Exceptions  (the  "Schedule  of  Exceptions")  furnished  to the  Investors,
specifically  identifying the relevant  subparagraph  hereof,  which  exceptions
shall be deemed to be representations and warranties as if made hereunder:

          2.1 Organization,  Valid Existence and Qualification. The Company is a
     corporation duly organized and validly existing under the laws of the state
     of Oregon and has all


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                                                            Page 22 of 92 Pages

     requisite  corporate  power and  authority  to carry on its business as now
     conducted.  Each of the corporations or other persons in which the Company,
     directly or  indirectly,  holds 50% or more of (i) the voting  power of the
     outstanding  voting  equity  securities  or (ii) the  outstanding  economic
     equity interest (each, a "Subsidiary")  is a corporation  duly organized or
     limited  liability  company duly formed and validly existing under the laws
     of the  state of its  incorporation  or  formation,  and has all  requisite
     corporate or limited  liability company power and authority to carry on its
     business as now conducted. The Company and each of its Subsidiaries is duly
     qualified to transact business and is in good standing in each jurisdiction
     in which the conduct of its business requires such qualification.

          2.2  Subsidiaries.  Neither the Company nor any  Subsidiary  presently
     owns or  controls,  directly  or  indirectly,  any  interest  in any  other
     corporation,  association  or other  entity.  Neither  the  Company nor any
     Subsidiary is a participant in any joint venture,  partnership,  or similar
     arrangement.

          2.3  Authorization.  All corporate  action on the part of the Company,
     its   officers,   directors   and   shareholders   necessary  for  (a)  the
     authorization, execution and delivery of this Agreement and the 2000 Second
     Amended and Restated  Investor Rights  Agreement of even date herewith,  by
     and  among  the  Company  and  the  Investors  (as  defined  therein)  (the
     "Investors'  Rights  Agreement")  and  the  Warrants   (collectively,   the
     "Transaction  Documents"),  (b) the  performance of all  obligations of the
     Company  hereunder  and  thereunder,  (c) the  authorization,  issuance (or
     reservation  for  issuance),  sale and  delivery  of the Series 1 Preferred
     Stock and Warrants  being sold  pursuant to this  Agreement  and the Common
     Stock  issuable  upon  conversion  of the  Series 1  Preferred  Stock  (the
     "Conversion Shares") and the exercise of the Warrants (the "Warrant Shares"
     and,  together  with the  Conversion  Shares,  the  "Shares"),  and (d) the
     authorization  and adoption of the Amended  Articles has been taken or will
     be taken prior to the Closing,  and the  Transaction  Documents  constitute
     valid and  legally  binding  obligations  of the  Company,  enforceable  in
     accordance with their respective terms, except (i) as limited by applicable
     bankruptcy,  insolvency,  reorganization,  moratorium,  and  other  laws of
     general application  affecting  enforcement of creditors' rights generally,
     (ii)  as  limited  by  laws  relating  to  the   availability  of  specific
     performance,  injunctive relief, or other equitable remedies,  and (iii) to
     the extent the indemnification  provisions contained in the Investor Rights
     Agreement may be limited by applicable federal or state securities laws.

          2.4 Valid Issuance of Preferred and Common Stock.

               (a) The Series 1 Preferred  Stock that is being  purchased by the
          Investors pursuant to this Agreement,  when issued, sold and delivered
          in accordance  with the terms of this Agreement for the  consideration
          expressed  herein,  will be duly and validly  issued,  fully paid, and
          nonassessable,  will be issued in compliance with the registration and
          qualification   requirements  of  all  applicable  federal  and  state
          securities laws and will be free and clear


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                                                            Page 23 of 92 Pages

          of all Liens (as defined in Section  2.6) other than  restrictions  on
          transfer  under the Amended  Articles,  this  Agreement  and the other
          Transaction   Documents  and  under   applicable   state  and  federal
          securities  laws.  The Shares have been duly and validly  reserved for
          issuance and, (i) in the case of the Conversion Shares,  upon issuance
          in accordance with the terms of the Amended  Articles and, (ii) in the
          case of the Warrant Shares, upon issuance in accordance with the terms
          of the  Warrants,  will be duly and validly  issued,  fully paid,  and
          nonassessable  and will be free  and  clear of all  Liens  other  than
          restrictions   on  transfer   under  this   Agreement  and  the  other
          Transaction   Documents  and  under   applicable   state  and  federal
          securities laws.

               (b) The issuance of the Series 1 Preferred Stock and the Warrants
          is not  subject to any  preemptive  rights or  similar  rights and the
          issuance of the Conversion  Shares upon the conversion of the Series 1
          Preferred  Stock  and the  Warrant  Shares  upon the  exercise  of the
          Warrants  will not be  subject  to any  preemptive  rights or  similar
          rights.  The Company has denied  preemptive rights to its shareholders
          as contemplated  by Section 60.174 of the Business  Corporation Act of
          Oregon,  as amended.  There are no approvals  or consents  required by
          Section  60.810 or Section 60.835 of the Oregon  Business  Corporation
          Act in  order  to  consummate  the  transactions  contemplated  by the
          Transaction Documents.

          2.5 Capitalization.

               (a) At the Closing the  authorized  capital  stock of the Company
          shall consist of 100,000,000 shares of Common Stock, 50,000,000 shares
          of  preferred  stock,  of  which  5,766,666  shares  shall  have  been
          designated Series 1 Preferred Stock. At December 17, 2000,  55,719,682
          shares of Common Stock (which  includes  shares of  restricted  Common
          Stock  described  below) and no shares of preferred  stock were issued
          and  outstanding.  At December  17, 2000,  2,287,844  shares of Common
          Stock  remained  available  for  issuance  under  the  Company's  1999
          Employee  Stock  Purchase  Plan.  At December 17, 2000,  the aggregate
          number of shares of restricted stock and options to purchase shares of
          Common Stock  available to be issued or granted  pursuant to any stock
          option plan or stock  incentive  plan of the Company or any Subsidiary
          was  959,779.  At December  17,  2000,  options to purchase  9,143,282
          shares  of Common  Stock  were  outstanding  and  2,210,750  shares of
          restricted  Common Stock had been issued under such plans.  Except for
          the Series 1 Preferred  Stock and the Warrants,  shares issuable under
          the Company's  1999 Employee Stock Purchase Plan and the stock options
          referred to in the preceding  sentence (as may be updated  pursuant to
          Section 5.16), there are no options, warrants,  conversion privileges,
          subscription or purchase rights or other rights presently  outstanding
          to purchase or  otherwise  acquire (x) any  authorized  but  unissued,
          unauthorized or treasury shares of the Company's  capital stock or (y)
          any  securities  of the Company  convertible  into or  exercisable  or
          exchangeable for shares of Common Stock, and there are no commitments,
          contracts, agreements, arrangements or understanding by the Company to
          issue any such securities.

               (b) The Company  owns all of the issued and  outstanding  capital
          stock of the  Subsidiaries,  free and clear of all Liens.  All of such
          shares of capital stock are duly  authorized,  validly  issued,  fully
          paid  and  nonassessable,  and  were  issued  in  compliance  with the
          registration and qualification  requirements of all applicable federal
          and state and foreign securities laws. There are no options, warrants,
          conversion privileges, subscription or purchase rights or other rights
          presently  outstanding to purchase or otherwise acquire any authorized
          but  unissued,  unauthorized  or treasury  shares of capital  stock or
          other  securities  of,  or any  proprietary  interest  in,  any of the
          Subsidiaries,  and  there  is no  outstanding  security  of  any  kind
          convertible  into or  exchangeable  for  such  shares  or  proprietary
          interest.

          2.6 No  Conflicts.  The  execution,  delivery and  performance  of the
     Transaction Documents by the Company and the consummation by the Company of
     the  transactions


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<PAGE>
                                                            Page 24 of 92 Pages

     contemplated  hereby  and  thereby  (including,   without  limitation,  the
     Company's  issuance of the Series 1 Preferred  Stock and  Warrants  and the
     reservation for issuance and issuance of the Shares) will not (i) result in
     a violation of the Company's 1999 Restated  Articles of  Incorporation,  as
     amended by the Amended Articles and as in effect on the date hereof, or the
     Company's  Bylaws,  as  amended  and as in effect on the date  hereof  (the
     "Bylaws") or (ii)  conflict  with, or constitute a breach or default (or an
     event which with  notice or lapse of time or both would  result in a breach
     or  default)  under,  or result in the  creation of any  mortgage,  deed of
     trust, pledge, hypothecation,  assignment,  encumbrance, lien (statutory or
     other)  or  preference,  priority,  right or  other  security  interest  or
     preferential  arrangement  of any  kind  or  nature  whatsoever  (excluding
     preferred stock and equity related  preferences)  (each, a "Lien"), or give
     to  others  any  rights  of   termination,   amendment,   acceleration   or
     cancellation of, any material  agreement,  indenture or instrument to which
     the Company or any  Subsidiary is a party  (except for possible  conflicts,
     breaches, defaults, terminations, amendments or other events that would not
     result in a  material  adverse  development  in the  business,  properties,
     operations,  financial condition, results of operations or prospects of the
     Company  and its  Subsidiaries,  taken  as a  whole  (a  "Material  Adverse
     Effect")),  or result in a violation of any law, rule,  regulation,  order,
     judgment  or  decree  (including  federal  and  state  securities  laws and
     regulations),  applicable to the Company or any  Subsidiary or by which any
     property or asset of the Company or any  Subsidiary  is bound or  affected.
     Except as  specifically  contemplated  by this Agreement in connection with
     (i) the listing of the Shares on Nasdaq  National Market  ("Nasdaq"),  (ii)
     registration  of the resale of the Series 1 Preferred  Stock and the Shares
     under the Securities Act of 1933, as amended (the "Act"),  as  contemplated
     by the  Investors'  Rights  Agreement,  and (iii) the filing of one of more
     Forms D with  respect  to the  Series 1  Preferred  Stock and the Shares as
     required  under  Regulation  D, the  Company is not  required to obtain any
     consent,  authorization  or order  of, or make any  filing or  registration
     with, any court or governmental agency or any regulatory or self-regulatory
     agency  in  order  for  it to  execute,  deliver  or  perform  any  of  its
     obligations   under  or  contemplated  by  the  Transaction   Documents  in
     accordance  with the terms hereof or thereof.  The Company is not, and upon
     consummation of the transactions  contemplated by the Transaction Documents
     will not be, in violation of the listing requirements of Nasdaq.

          2.7 Offering.  Assuming the accuracy of the Investors' representations
     set forth in Section 3 of this Agreement,  the offer,  sale and issuance of
     the  Units  as   contemplated   by  this  Agreement  are  exempt  from  the
     registration   requirements   of  the  Act  and  from   the   qualification
     requirements of the Oregon  Securities Law, and neither the Company nor any
     authorized  agent acting on its behalf will take any action  hereafter that
     would cause the loss of such exemption.

          2.8  SEC  Documents;  Financial  Statements.  As of the  Closing,  the
     Company  shall have filed all reports,  schedules,  forms,  statements  and
     other documents required to be filed by it with the Securities and Exchange
     Commission ("SEC") pursuant to the reporting requirements of the Securities
     Exchange  Act of 1934,  as amended  (the "1934 Act") (all of the  foregoing
     filed  prior to the date  hereof  and all  exhibits  included  therein  and
     financial  statements and schedules  thereto and documents  incorporated by
     reference therein being hereinafter referred to as the "SEC Documents"). As
     of their  respective  dates,  the SEC  Documents  complied in all  material
     respects  with  the  requirements  of  the  1934  Act  and  the  rules  and
     regulations  of the  SEC  promulgated  thereunder  applicable  to  the  SEC
     Documents,  and none of the SEC Documents, at the time they were filed with
     the SEC,  contained  any untrue  statement of a material fact or


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                                                            Page 25 of 92 Pages

     omitted to state a material fact required to be stated therein or necessary
     in order  to make the  statements  therein,  in light of the  circumstances
     under which they were made, not misleading.  As of their respective  dates,
     the  financial  statements  of the Company  included  in the SEC  Documents
     complied as to form in all material  respects  with  applicable  accounting
     requirements  and the  published  rules  and  regulations  of the SEC  with
     respect thereto. Such financial statements have been prepared in accordance
     with generally accepted accounting principles, consistently applied, during
     the periods involved (except in the case of unaudited  interim  statements,
     to the extent they may exclude  footnotes  or may be  condensed  or summary
     statements)  and fairly  present in all  material  respects  the  financial
     position  of the  Company as of the dates  thereof  and the  results of its
     operations and cash flows for the periods then ended (subject,  in the case
     of unaudited  statements,  to normal year-end audit adjustments).  No other
     information  provided by or on behalf of the Company to the Investors which
     is not included in the SEC  Documents  contains  any untrue  statement of a
     material  fact or omits to state any  material  fact  necessary in order to
     make the statements  therein,  in the light of the circumstance under which
     they are or were made, not misleading.

          2.9 Absence of Certain Changes.  Since the Company's Form 10-Q for the
     quarter ended September 30, 2000 (the "Most Recent Filing"), there has been
     no  material  adverse  change and no  development  that  would  result in a
     Material  Adverse Effect.  Neither the Company nor any of its  Subsidiaries
     has taken any steps,  and does not currently  expect to take any steps,  to
     seek protection  pursuant to any bankruptcy law nor does the Company or any
     of its  Subsidiaries  have any  knowledge  or  reason to  believe  that its
     creditors intend to initiate involuntary bankruptcy proceedings.

          2.10  Liabilities.  Neither  the Company  nor any  Subsidiary  has any
     direct or indirect obligation or liability and, to the Company's knowledge,
     there is no existing condition,  event or arrangement that could reasonably
     be expected to give rise to such an obligation or liability, other than (a)
     those  provided  for in  the  financial  statements  included  in  the  SEC
     Documents  and (b)  those  incurred  since  the Most  Recent  Filing in the
     ordinary course of business consistent with past practices.

          2.11 Material Contracts. Each of the agreements, contracts, leases and
     other  commitments  listed as an exhibit to any SEC  Document  filed  since
     January 1, 2000 (each, a "Material Contract") is a legal, valid and binding
     agreement of the Company or a Subsidiary,  and is in full force and effect,
     except to the extent such agreement has been fully  performed or terminated
     pursuant to its terms, and, to the Company's knowledge, no party thereto is
     in default or breach,  and there exists no event or circumstance  that with
     notice  or lapse of time or both  would  constitute  a  default  or  breach
     thereunder, except in each case for those defaults and breaches which could
     not reasonably be expected,  either  individually  or in the aggregate,  to
     result in a Material Adverse Effect.

          2.12 Absence of Litigation.  Except as set forth in the SEC Documents,
     there is no action, suit, proceeding, inquiry or investigation before or by
     any court, public board, government agency, self-regulatory organization or
     body pending or, to the  knowledge of the  Company,  threatened  against or
     affecting  the  Company,  any  Subsidiary  or any of the  Company's  or any
     Subsidiary's  officers or directors in their  capacities as such that would
     have a Material


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                                                            Page 26 of 92 Pages

     Adverse Effect and, to the knowledge of the Company, there is no reasonable
     basis for any of the foregoing.

          2.13 Intellectual Property.

               (a) The Company or one of its  Subsidiaries  owns, or has a valid
          license to use, all patents,  trademarks,  service marks, trade names,
          copyrights,   trade  secrets,  domain  names,  software,   technology,
          know-how and other intellectual property (the "Intellectual Property")
          necessary to or used in the conduct of the business of the Company and
          its Subsidiaries as now conducted and as proposed to be conducted. All
          Intellectual  Property owned by the Company or any of its Subsidiaries
          is owned by them free and clear of all Liens.  To the knowledge of the
          Company,   the  conduct  of  the  business  of  the  Company  and  its
          Subsidiaries  does not conflict with or infringe upon any Intellectual
          Property  rights of any other  person  and no  claims of  conflict  or
          infringement  are pending or threatened  against the Company or any of
          its Subsidiaries  which, in any event, would reasonably be expected to
          have a Material Adverse Effect.

               (b)  All  of the  Intellectual  Property  licenses,  sublicenses,
          distributor agreements and other agreements under which the Company or
          any   Subsidiary  is  either  a  licensor,   licensee  or  distributor
          (excluding  those  related  to  off-the-shelf   software  commercially
          available  on a retail  basis and used solely on the  computers of the
          Company  and/or any  Subsidiary)  are valid,  enforceable  and in full
          force and  effect,  and neither  the  Company  nor any  Subsidiary  is
          required to pay any  royalty  payment  pursuant to any such  agreement
          (except for such  agreements  that were  entered  into in the ordinary
          course of business consistent with past practice). Except as set forth
          in the SEC  Documents,  no  former  employer  of any  employee  of the
          Company or any  Subsidiary,  and no  current  or former  client of any
          consultant of the Company or any Subsidiary,  has made a claim against
          the Company or any Subsidiary or, to the Company's knowledge,  against
          any other  person,  that such  employee  or  consultant  is  utilizing
          Intellectual Property of such former employer or client.

               (c) The Company has policies and procedures that provide that all
          employees  of the  Company  and each  Subsidiary  execute  and deliver
          proprietary  invention  agreements with the Company,  and be obligated
          under the terms thereof to assign all  inventions  made by them during
          the course of  employment to the Company or such  Subsidiary,  and the
          Company  uses  its  best  efforts  to  abide  by  those  policies  and
          procedures.

          2.14  Compliance with Other  Instruments.  Neither the Company nor any
     Subsidiary  is in violation or default in any respect (i) of any  provision
     of its 1999 Restated Articles of  Incorporation,  as amended by the Amended
     Articles (when filed),  or Bylaws,  or (ii) of any judgment,  order,  writ,
     decree to which it is a party or by which it is bound,  or of any provision
     of any federal or state  statute,  rule or regulation  applicable to it, or
     (iii) of any  agreement,  indenture  or  instrument  to which it is a party
     (except for  violations  or defaults with respect to clauses (ii) and (iii)
     that would not have a Material Adverse Effect). The execution, delivery and
     performance  of the  Transaction  Documents,  and the  consummation  of the
     transactions  contemplated  hereby and thereby  will not result in any such
     violation or be in conflict with or constitute, with or without the passage
     of time and giving of notice,  either a default  under any such  provision,
     instrument,  judgment,  order,  writ,  decree or  contract or an


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                                                            Page 27 of 92 Pages

     event  that  results  in the  creation  of any Lien upon any  assets of the
     Company  or  the  suspension,   revocation,   impairment,   forfeiture,  or
     nonrenewal  of any  material  permit,  license,  authorization  or approval
     applicable to the Company,  its business or operations or any of its assets
     or properties (except for violations,  conflicts, defaults, liens, damages,
     encumbrances,  suspensions,  revocations,  impairments or forfeitures  that
     would not, either individually or in the aggregate, have a Material Adverse
     Effect).

          2.15  Related-Party  Transactions.  Except  as set  forth  in the  SEC
     Documents,  no 5% or  greater  shareholder  of  the  Company,  officer,  or
     director of the Company or any Subsidiary or member of his or her immediate
     family is  indebted  to the  Company  in any  material  amount,  nor is the
     Company indebted (or committed to make loans or extend or guarantee credit)
     to any of  them  in any  material  amount.  To the  best  of the  Company's
     knowledge,  none of the  Company's  officers or directors has any direct or
     indirect  ownership  interest  in any firm or  corporation  with  which the
     Company or any  Subsidiary  is  affiliated or with which the Company or any
     Subsidiary has a business  relationship,  or any firm or  corporation  that
     competes  with the  Company or any  Subsidiary,  except  that  officers  or
     directors  of the Company and members of their  immediate  families may own
     less than 2% of the outstanding stock in a publicly traded company that may
     compete with the Company.  No member of the immediate family of any officer
     or director of the Company is  directly  or  indirectly  interested  in any
     material contract with the Company.  None of the foregoing  transactions is
     currently contemplated by the Company.

          2.16  Permits.  The  Company  and  each of its  Subsidiaries  have all
     franchises,  permits,  licenses and any similar authority necessary for the
     conduct of its business as now being  conducted or proposed to be conducted
     by it, the lack of which could  result in a Material  Adverse  Effect.  The
     Company  is not in  default  in any  material  respect  under  any of  such
     franchises, permits, licenses, or other similar authority.

          2.17 Outstanding  Borrowing.  Except as set forth in the SEC Documents
     and  incurred  in the  ordinary  course of  business  consistent  with past
     practices,  since the Most  Recent  Filing,  neither  the  Company  nor any
     Subsidiary has (a) any obligation  for borrowed money  (including,  without
     limitation,  reimbursement  or other  obligations  with  respect  to surety
     bonds, letters of credit and bankers' acceptances, whether or not matured),
     (b) any  obligation  to pay the  deferred  purchase  price of  property  or
     services,  except trade  accounts  payable and accrued  commercial or trade
     liabilities  arising in the ordinary  course of  business,  (c) any payment
     obligation, whether periodic or upon the occurrence of a contingency, under
     any interest rate or currency  swap,  cap,  collar or similar  agreement or
     hedging device,  (d) indebtedness  created or arising under any conditional
     sale or other title retention  agreement with respect to property  acquired
     by such party (even  though the rights and remedies of the seller or lender
     under such agreement in the event of default are limited to repossession or
     sale of such property),  (e) any obligation under leases which have been or
     should be, in accordance  with generally  accepted  accounting  principles,
     recorded as capital leases, (f) any indebtedness secured by any Lien (other
     than Liens in favor of lessors  under leases other than leases  included in
     clause (e)) on any property or asset owned or held by such party regardless
     of whether the indebtedness secured thereby shall have been assumed by that
     party or is nonrecourse to the credit of that party,  and (g) any direct or
     indirect  liability  with respect to any obligation of a third party of the
     type  described in clauses (a) through (e) of this  section  (the  "Primary
     Obligation"),  whether or not


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                                                            Page 28 of 92 Pages

     contingent,  (i) to purchase,  repurchase or otherwise acquire such Primary
     Obligation  or  any  property  constituting  direct  or  indirect  security
     therefor,  (ii) to advance or provide funds for the payment or discharge of
     any such  Primary  Obligation  or to  maintain  working  capital  or equity
     capital  of the  third  party or to  otherwise  maintain  the net  worth or
     solvency of any balance sheet item, level of income or financial  condition
     of such third party,  (iii) to purchase  property,  securities  or services
     primarily  for the  purpose  of  assuring  the  owner of any  such  Primary
     Obligation  of the  ability  of such  third  party to make  payment of such
     Primary Obligation,  or (iv) to otherwise assure or hold harmless the owner
     of any such  Primary  Obligation  against  loss or failure or  inability to
     perform in respect thereof.

          2.18 Environmental and Safety Laws. The Company is not in violation of
     any applicable  statute,  law or regulation  relating to the environment or
     occupational health and safety, and no material expenditures are or will be
     required  in  order  to  comply  with any  such  existing  statute,  law or
     regulation.

          2.19  Manufacturing and Marketing Rights.  The Company has not granted
     rights  to  manufacture,  produce,  assemble,  license,  market or sell its
     products to any other person and is not bound by any agreement that affects
     the  Company's   exclusive   right  to  develop,   manufacture,   assemble,
     distribute, market or sell its products.

          2.20  Disclosure.  Neither  the  Transaction  Documents  nor any other
     statements  or  certificates  made or  delivered  in  connection  therewith
     contains  any  untrue  statement  of a  material  fact or  omits to state a
     material fact necessary to make the  statements  made herein or therein not
     misleading.

          2.21  Registration  Rights.  Except as provided in the Investor Rights
     Agreement,  the Company has not granted or agreed to grant any registration
     rights, including piggyback rights, to any person or entity.

          2.22 Title to  Property  and Assets.  The Company and each  Subsidiary
     owns their  respective  properties  and assets free and clear of all Liens,
     except such Liens that arise in the ordinary  course of business and do not
     materially  impair  the  Company's  ownership  or use of such  property  or
     assets.  With respect to the property and assets it leases,  the Company is
     in compliance with such leases and, to the best of the Company's knowledge,
     such  leases are in full force and  effect  and the  Company  holds a valid
     leasehold  interest  free of any  Liens.  No other  property  or assets are
     necessary  to the  conduct of their  respective  businesses,  as  presently
     conducted or as proposed to be conducted.

          2.23 Taxes.

               (a) The Company and each of its Subsidiaries has timely filed all
          income,  franchise and other material tax returns,  reports, forms and
          other such documents ("Tax Returns")  required to be filed by it prior
          to the date  hereof.  Such Tax  Returns  are true and  correct  in all
          material  respects.  The Company and each of its Subsidiaries has paid
          or caused to be paid all Tax  liabilities  for all  fiscal  years that
          have not been  examined and closed by any Tax  authority (or closed by
          applicable  statutes).  No additional Tax  assessment,  Tax deficiency
          (whether  assessed  or  unassessed)  or  claim  for  additional  Taxes
          (including interest thereon and


                                       8
<PAGE>
                                                            Page 29 of 92 Pages

          penalties in connection  therewith)  has been  heretofore  proposed or
          threatened  by any Tax  authority  and no audit is in progress  and no
          extension  of time is in force  with  respect to any date on which any
          Tax Return is to be filed and no waiver or  agreement  is in force for
          the  extension  of time  for the  assessment  or  payment  of any Tax.
          Neither  the  Company nor any  Subsidiary  has made an election  under
          Section 341(f) of the Code

               (b) There are no Liens  for Taxes  (other  than for taxes not yet
          due and payable) upon the assets of the Company or any Subsidiary.

               (c) Neither the  Company or any  Subsidiary  (i) is a party to or
          bound by, or has any obligations  under, any tax allocation,  sharing,
          indemnity or similar  agreement or arrangement,  (ii) is or has been a
          member of any consolidated, combined or unitary group of corporations,
          other  than a group of which the  Company is the  common  parent,  for
          purposes of filing tax returns or paying taxes and (iii) other than as
          a result  of being a member of a  consolidated,  combined  or  unitary
          group of  corporations  of which the Company is the common parent,  is
          liable for the taxes of any other Person,  under Treasury  Regulations
          section 1.1502-6 (or any similar provision of foreign,  state or local
          law) or as a transferee, successor or otherwise.

               (d)  Neither the  Company  nor any  Subsidiary  is a party to any
          agreement,  contract,  arrangement  or plan that has resulted or would
          result,  separately or in the aggregate, in the payment of any "excess
          parachute  payments" within the meaning of section 280G of the Code or
          any similar provision of foreign,  state or local law as a result of a
          transaction occurring on or before the date hereof.

               (e)  Neither  the  Company  nor any  Subsidiary  has ever  been a
          "United States real property holding corporation" (a "USRPHC") as that
          term is  defined  in Section  897(c)(2)  of the Code and the  treasury
          regulations promulgated thereunder (the "Treasury  Regulations").  (f)
          There are no (i) outstanding rulings of, or requests for rulings with,
          the Internal  Revenue Service or any other Tax authority  addressed to
          the  Company  or any  Subsidiary,  that are,  or if  issued  would be,
          binding on the Company or any Subsidiary, (ii) closing agreements with
          any Tax authority and (iii) other binding agreements entered into with
          any Tax authority.  The Company and each  Subsidiary have provided the
          Investors with copies of any such rulings,  ruling  requests,  closing
          agreement or other binding agreements.

               (g)  Neither  the   Company  nor  any   Subsidiary   has  been  a
          "distributing  corporation" or a "controlled  corporation" (within the
          meaning  of  Section  355 of the  Code)  in a  distribution  of  stock
          qualifying for tax-free treatment under Section 355 of the Code in the
          two years prior to the date of this Agreement.

               (h) As  used  in this  Agreement,  "Tax"  or  "Taxes"  means  any
          federal,  state,  county,  local,  foreign and other taxes (including,
          without  limitation,  income,  profits,  premium,  estimated,  excise,
          sales,  use,  occupancy,   gross  receipts,   franchise,  ad  valorem,
          severance,   capital   levy,   production,    transfer,   withholding,
          employment,  unemployment  compensation,  payroll and property  taxes,
          import duties and other governmental charges and assessments), whether
          or not  measured  in whole  or in part by net  income,  and  including
          deficiencies,  interest,  additions to tax or interest,  and penalties
          with  respect  thereto,   and


                                       9
<PAGE>
                                                            Page 30 of 92 Pages

          including expenses associated with contesting any proposed adjustments
          related  to any of the  foregoing,  except  that  they do not  contain
          footnotes or normal period-end adjustments.

          2.24 Insurance.  The Company and each of its  Subsidiaries has in full
     force and effect insurance  policies in such amounts and against such risks
     as are customarily maintained and insured against by comparable businesses.
     The Company has in full force and effect products  liability and errors and
     omissions  insurance in amounts customary for companies similarly situated.
     All such policies are listed on the Schedule of  Exceptions,  together with
     the effective date and coverage amounts with respect thereto.

          2.25  Labor  Agreements  and  Actions.  Neither  the  Company  nor any
     Subsidiary  is bound by or subject to (and none of its assets or properties
     is  bound by or  subject  to) any  written  or oral,  express  or  implied,
     contract,  commitment  or  arrangement  with any labor union,  and no labor
     union has requested or, to the best of the Company's knowledge,  has sought
     to represent any of the employees, representatives or agents of the Company
     or any Subsidiary.  There is no strike or other labor dispute involving the
     Company  or any  Subsidiary  pending,  or to  the  best  of  the  Company's
     knowledge,  threatened,  that could have a Material Adverse Effect,  nor is
     the  Company  aware  of  any  labor  organization  activity  involving  its
     employees.  To the  best of the  Company's  knowledge,  no  officer  or key
     employee,  or any  group  of key  employees,  intends  to  terminate  their
     employment  with the  Company or any  Subsidiary.  The  employment  of each
     officer and employee of the Company or any  Subsidiary is terminable at the
     will of the  Company or any  Subsidiary,  and  neither  the Company nor any
     Subsidiary has an employment  agreement  with any officer.  The Company and
     each Subsidiary has complied in all respects with all applicable  state and
     federal equal employment opportunity and other laws related to employment.

          2.26  "Company's  Knowledge"  Defined.  As used in this Section 2, the
     terms "to the best of the Company's  knowledge,"  "to the best knowledge of
     the  Company,"  or "known to the Company"  shall mean the  knowledge of the
     Company,  its  Subsidiaries  and the officers,  directors and management of
     each,  after  careful  consideration  of  the  matters  set  forth  in  the
     representation that is so qualified.

          2.27 Eligibility. As of December 9, 2000, the Company will be eligible
     to register  the resale of the Unit Shares on a  registration  statement on
     Form S-3 under the Act.

          2.28 Employee  Benefit  Plans.  The Company does not have any Employee
     Benefit Plan as defined in the Employee  Retirement  Income Security Act of
     1974, as amended.

     3. Representations and Warranties of the Investors. Each Investor severally
and not jointly hereby represents and warrants that:

          3.1 Authorization. Such Investor has full power and authority to enter
     into the  Transaction  Documents  to which  it is a  party,  and each  such
     agreement constitutes its valid and legally binding obligation  enforceable
     in  accordance  with  its  terms,  except  (i)  as  limited  by  applicable
     bankruptcy,  insolvency,  reorganization,  moratorium,  and  other  laws of
     general application  affecting  enforcement of creditors' rights generally,
     (ii)  as  limited  by  laws  relating  to  the   availability  of  specific
     performance,  injunctive relief, or other equitable remedies,  and (iii) to

                                       10
<PAGE>
                                                            Page 31 of 92 Pages

     the extent the indemnification  provisions contained in the Investor Rights
     Agreement may be limited by applicable federal or state securities laws.

          3.2 Purchase Entirely for Own Account. This Agreement is made with the
     Investors in reliance upon such Investor's  representations to the Company,
     that the  Series 1  Preferred  Stock and  Warrant  to be  received  by such
     Investor and the Shares (the  "Securities") will be acquired for investment
     for such Investor's own account in the ordinary course of business,  not as
     a nominee or agent,  and not with a view to the resale or  distribution  of
     any  part  thereof,  and  that  such  Investor  has no  present  intention,
     agreements or understandings,  directly or indirectly, of selling, granting
     any participation in, or otherwise distributing the same. By executing this
     Agreement,  such  Investor  further  represents  that it does  not have any
     contract,  undertaking,  agreement or arrangement  with any person to sell,
     transfer or grant  participations  to such  person or to any third  person,
     with respect to any of the Securities.

          3.3 Disclosure of  Information.  Such Investor  represents that it has
     had an  opportunity  to ask questions and receive  answers from the Company
     regarding  the  terms  and  conditions  of the  offering  of the  Series  1
     Preferred  Stock and Warrant and the  business,  properties,  prospects and
     financial condition of the Company. The foregoing,  however, does not limit
     or modify the representations and warranties of the Company in Section 2 of
     this Agreement or the right of such Investor to rely thereon.

          3.4 Investment Experience.  Such Investor is an investor in securities
     of companies in the development stage and acknowledges that it can bear the
     economic risk of its  investment,  and has such knowledge and experience in
     financial or business  matters that it is capable of evaluating  the merits
     and risks of the  investment in the Series 1 Preferred  Stock and Warrants.
     Such  Investor  has not been  organized  for the purpose of  acquiring  the
     Series 1 Preferred Stock and Warrants.

          3.5 Accredited  Investor.  Such Investor is an  "accredited  investor"
     within the meaning of Rule 501  promulgated  under the Act, as presently in
     effect.

          3.6  Restricted   Securities.   Such  Investor  understands  that  the
     Securities it is purchasing are  characterized  as "restricted  securities"
     under the federal  securities laws inasmuch as they are being acquired from
     the Company in a transaction not involving a public offering and that under
     such laws and applicable regulations such securities may be resold, without
     registration under the Act, only in certain limited circumstances.  In this
     connection,  such  Investor  represents  that it is familiar  with Rule 144
     promulgated  under the Act, as presently  in effect,  and  understands  the
     resale limitations imposed thereby and by the Act.

          3.7 Further  Limitations on  Disposition.  Without in any way limiting
     the  representations  set forth above,  such  Investor  (and,  by accepting
     delivery of the Securities, each transferee) further agrees not to make any
     disposition  of all or any portion of the Securities  that are  "restricted
     securities" under the Act unless,  if reasonably  requested by the Company,
     such Investor  shall have furnished the Company with an opinion of counsel,
     reasonably  satisfactory  to the  Company  that such  disposition  will not
     require  registration  of such shares under the Act. Such opinion shall not
     be required if there is then in effect a Registration  Statement  under the

                                       11
<PAGE>
                                                            Page 32 of 92 Pages

     Act covering  such proposed  disposition  and such  disposition  is made in
     accordance with such Registration Statement.

          3.8 Legends.  It is understood  that the  certificates  evidencing the
     Securities may bear legends similar to the following:

               (a) THE SECURITIES  REPRESENTED  HEREBY HAVE NOT BEEN  REGISTERED
          UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE "ACT"), OR UNDER THE
          SECURITIES  LAWS OF CERTAIN  STATES.  THESE  SECURITIES ARE SUBJECT TO
          RESTRICTIONS  ON  TRANSFERABILITY  AND RESALE AND MAY NOT BE  OFFERED,
          SOLD OR  OTHERWISE  TRANSFERRED,  PLEDGED  OR  HYPOTHECATED  EXCEPT AS
          PERMITTED  UNDER THE ACT AND THE  APPLICABLE  STATE  SECURITIES  LAWS,
          PURSUANT TO REGISTRATION OR EXEMPTION THEREFROM.  EACH INVESTOR SHOULD
          BE AWARE THAT IT MAY BE REQUIRED TO BEAR THE  FINANCIAL  RISKS OF THIS
          INVESTMENT  FOR AN  INDEFINITE  PERIOD  OF TIME.  THE  ISSUER OF THESE
          SECURITIES  MAY  REQUIRE AN  OPINION OF COUNSEL IN FORM AND  SUBSTANCE
          SATISFACTORY TO THE ISSUER TO THE EFFECT THAT ANY PROPOSED TRANSFER OR
          RESALE IS IN COMPLIANCE WITH THE ACT, UNLESS THE SECURITIES ARE RESOLD
          IN COMPLIANCE WITH RULE 144, AND ANY APPLICABLE STATE SECURITIES LAWS.

               (b) A  FULL  STATEMENT  OF  THE  DESIGNATIONS,  RELATIVE  RIGHTS,
          PREFERENCES  AND  LIMITATIONS  OF THE SHARES OF EACH CLASS OF STOCK OF
          THE ISSUER,  THE  VARIATIONS  IN THE RELATIVE  RIGHTS AND  PREFERENCES
          BETWEEN THE SHARES OF EACH SERIES OF  PREFERRED  STOCK SO FAR AS FIXED
          AND  DETERMINED,  AND THE  AUTHORITY  OF THE  BOARD  OF  DIRECTORS  TO
          DETERMINE  VARIATIONS  FOR FUTURE SERIES MAY BE OBTAINED AT NO COST BY
          WRITTEN  REQUEST MADE BY THE RECORD HOLDER OF THIS  CERTIFICATE TO THE
          SECRETARY OF THE ISSUER AT ITS PRINCIPAL OFFICE.

               (c) THE SHARES  REPRESENTED  BY THIS  CERTIFICATE  ARE SUBJECT TO
          CERTAIN  TRANSFER  RESTRICTIONS  AS  SET  FORTH  IN  A  UNIT  PURCHASE
          AGREEMENT TO WHICH THE ORIGINAL  HOLDER OF THESE SHARES IS A PARTY,  A
          COPY OF WHICH MAY BE OBTAINED AT THE  PRINCIPAL  OFFICE OF THE ISSUER.
          SUCH TRANSFER RESTRICTIONS ARE BINDING ON TRANSFEREES OF THESE SHARES.

     4. Covenants of the Company.

          4.1 Conduct of  Business.  From the date of this  Agreement  until the
     Closing,  the Company  will (a) conduct its  business in a  reasonable  and
     prudent manner and in accordance with its normal  practices;  (b) engage in
     no transaction (including, without limitation, capital expenditures) out of
     the ordinary course of its business and consistent with past practices; (c)
     not dispose of any of its assets or  properties  except to the extent these
     are used,  retired or replaced in the ordinary course of its business;  (d)
     conduct its business in accordance  with all applicable  laws,  regulations
     and ordinances;  (e) maintain and keep in force any governmental  licenses,
     permits,  authorizations,  consents or approvals required by the Company to
     own its assets and


                                       12
<PAGE>
                                                            Page 33 of 92 Pages

     properties or to carry on its business as currently conducted; (f) maintain
     and keep in  force  its  Intellectual  Property  rights;  (g)  perform  all
     material  obligations  required  to be  performed  by it  under  any of the
     Material  Contracts;  (h) refrain  from  entering  into  transactions  with
     affiliates  of the Company;  (i) not pay dividends to, or redeem the shares
     of,  stockholders of the Company other than pursuant to existing restricted
     stock  purchase  agreement  with current or former  employees;  and (j) not
     amend the 1999 Restated Articles of Incorporation or Bylaws of the Company.

          4.2 Anti-dilution.

               (a) The Company shall not,  without first  obtaining  shareholder
          approval, issue shares of Common Stock or Other Securities (as defined
          in the Amended Articles) for a per share  consideration  less than (i)
          the then-current Conversion Price (as defined in the Amended Articles)
          or (ii) the Fair Market Price (as defined in the Amended  Articles) of
          the Common Stock at the time of such issuance,  if such issuance would
          violate Nasdaq Marketplace Rule 4460(i)(1)(D)(i).

               (b) The  Company  shall  use  its  best  efforts  to  obtain  the
          shareholder approval necessary to allow it to make any adjustments (i)
          to the  Conversion  Price or otherwise  required by the  anti-dilution
          provisions  set forth in the Amended  Articles  and (ii) the  Exercise
          Price  (as  defined  in the  Warrant)  or  otherwise  required  by the
          anti-dilution   provisions  set  forth  in  the  Warrant  without  any
          subsequent shareholder approval, in compliance with Nasdaq Marketplace
          Rule 4460(i)(1)(D)(i),  at its next regularly scheduled annual meeting
          of shareholders following the Closing.

          4.3  Registration.  The  Company  shall use its efforts to prepare and
     file with the SEC,  within  sixty  (60) days  after the  Closing  and after
     giving  Investors' legal counsel  reasonable time to review and comment,  a
     registration  statement  to  register  the  resale  of  the  Shares  by the
     Investors  from time to time under the Act.  This  filing and  registration
     shall  be  treated  as a  request  for  registration  pursuant  to  Section
     1.2(a)(iii)  of the  Investors'  Rights  Agreement  and shall  otherwise be
     governed by the terms and  conditions  set forth in the  Investors'  Rights
     Agreement.

     5. Conditions of Investors'  Obligations at Closing. The obligations of the
Investors  under  subsection  1.1(b)  of  this  Agreement  are  subject  to  the
fulfillment  on or before the Closing of each of the following  conditions,  the
waiver of which shall not be effective against any Investor who does not consent
in writing thereto:

          5.1 Representations and Warranties. The representations and warranties
     of the  Company  contained  in  Section  2 shall  be  true in all  material
     respects  on and as of the  Closing  with the same  effect as  though  such
     representations  and warranties had been made on and as of the date of such
     Closing.

          5.2 Performance.  The Company shall have performed and complied in all
     material respects with all agreements, obligations and conditions contained
     in this  Agreement that are required to be performed or complied with by it
     on or before the Closing.



                                       13
<PAGE>
                                                            Page 34 of 92 Pages

          5.3 Compliance Certificate. The President of the Company shall deliver
     to the Investors at the Closing a certificate  stating that the  conditions
     specified  in Sections  5.1 and 5.2 have been  fulfilled  and stating  that
     there shall have been no material adverse change in the business,  affairs,
     prospects, operations, properties, assets or condition of the Company since
     the date of the financial statements contained in the Most Recent Filing.

          5.4 Qualifications. All authorizations, approvals, or permits, if any,
     of any governmental authority or regulatory body of the United States or of
     any state that are required in connection with the lawful issuance and sale
     of the  Securities  pursuant to this  Agreement  shall be duly obtained and
     effective as of the Closing.

          5.5 Proceedings and Documents.  All corporate and other proceedings in
     connection  with  the  transactions  contemplated  at the  Closing  and all
     documents  incident  thereto shall be reasonably  satisfactory  in form and
     substance  to  the  Investors,  and  they  shall  have  received  all  such
     counterpart  original and  certified  or other copies of such  documents as
     they may reasonably request.

          5.6 Board of  Directors.  The  directors  of the Company as of Closing
     shall consist of the following individuals, and may include up to two other
     individuals to be appointed by the Board of Directors:

                           Bruce Fried
                           C. Martin Harris, M.D.
                           Ronald H. Kase
                           Mark Leavitt, M.D.
                           Arthur Leibowitz, M.D.
                           George Lundberg, M.D.
                           David C. Moffenbeier
                           Neal Moszkowski
                           Mark A. Stevens

          5.7 Articles of  Amendment.  The Company  shall have filed the Amended
     Articles with the Secretary of State of Oregon and the Investors shall have
     received evidence of such filing prior to the Closing.

          5.8 Opinion of Company Counsel. The Investors shall have received from
     Stoel Rives LLP,  counsel  for the  Company,  an  opinion,  dated as of the
     Closing, in the form attached hereto as Exhibit C.

          5.9 Certificate of Existence.  The Company shall have delivered to the
     Investors a  certificate  dated as of a recent date issued by the Secretary
     of State of the State of Oregon to the effect  that the  Company is validly
     existing.

          5.10 Secretary's Certificate.  The Company shall have delivered to the
     Investors a  certificate  executed by the Secretary of the Company dated as
     of the Closing,  certifying the following matters:  (a) resolutions adopted
     by  the  Company's  Board  of  Directors   relating  to  the   transactions
     contemplated by this Agreement;  (b) Amended  Articles of the


                                       14
<PAGE>
                                                            Page 35 of 92 Pages

     Company;  (c) Bylaws of the  Company;  (d)  incumbency  of  officers of the
     Company;  and (e)  such  other  matters  as the  Investors  may  reasonably
     request.

          5.11 Investor  Rights  Agreement.  The Company,  the Investors and the
     holders of a majority of the outstanding Registrable Securities (as defined
     in the 2000 Amended and Restated Investor Rights  Agreement,  dated May 19,
     2000, among the Company and the shareholders  signatory thereto) shall have
     entered into the Investor Rights  Agreement in the form attached as Exhibit
     D.

          5.12 Minimum Investment.  The Company shall have received an aggregate
     minimum investment from the Investors of $17,000,000.

          5.13 Nasdaq  Approval.  The Investors  shall have received  reasonably
     satisfactory  evidence that Nasdaq has approved (i) the proposals set forth
     by the Company in (a) the letter dated  December 6, 2000 and (b) the letter
     dated  December  11, 2000 from the Company to the office of Nasdaq  Listing
     Qualifications  and (ii) the  Shares for  listing  on the  Nasdaq  National
     Market.

          5.14  Due  Diligence.  The  Investor's  counsel  shall  be  reasonably
     satisfied  with the  results of its due  diligence  inquiry  regarding  the
     outstanding litigation of the Company and its Subsidiaries.

          5.15 Adverse Change.  There shall have been no material adverse change
     in the  Company's  business  from that  reported in the Most Recent  Filing
     prior to the Closing.  For purposes of this Section 5.13, "material adverse
     change" means a circumstance,  fact, change, development or effect (i) that
     has been, could or could reasonably be expected to be materially adverse to
     the properties,  business,  prospects,  results of operations or condition,
     financial  or  otherwise,  of the  Company  taken as a whole  or (ii)  that
     adversely effects the ability of the Company to consummate the transactions
     contemplated by the Transaction  Documents or materially  impairs or delays
     the  ability  of the  Company  to effect  the  Closing  or (iii) that could
     reasonably  be  expected  to require a material  expenditure  by any of the
     Company, a Subsidiary or the Investors.

          5.16 Capitalization  Schedule. The Company shall have delivered to the
     Investors a schedule reasonably  satisfactory to the Investors  reflecting,
     after giving effect to the transactions contemplated by this Agreement, (i)
     the Company's authorized, issued and outstanding shares of Common Stock and
     Series 1  Preferred  Stock  and (ii) the  aggregate  number  of  shares  of
     restricted  stock and options to purchase  shares of Common Stock which may
     be issued and which have been granted  pursuant to any stock option plan or
     stock  incentive  plan of the  Company or any  Subsidiary  or are  issuable
     pursuant  to  the  Company's   1999  Employee   Stock  Purchase  Plan.  The
     information in such Schedule shall be as of the Closing.

          5.17 Viacom  Waiver.  The  Investors  shall have  received a copy of a
     waiver, in form reasonably satisfactory to Investor's counsel,  executed by
     Viacom waiving its right of participation in the transactions  contemplated
     by this Agreement.



                                       15
<PAGE>
                                                            Page 36 of 92 Pages

     6. Conditions of the Company's  Obligations at Closing.  The obligations of
the Company to the Investors under this Agreement are subject to the fulfillment
on or before the Closing of each of the following conditions by the Investors:

          6.1 Representations and Warranties. The representations and warranties
     of the  Investors  contained  in  Section  3 shall be true on and as of the
     Closing with the same effect as though such  representations and warranties
     had been made on and as of the Closing.

          6.2 Payment of Purchase Price.  The Investors shall have delivered the
     purchase price specified in Section 1.

          6.3 Qualifications. All authorizations, approvals, or permits, if any,
     of any governmental authority or regulatory body of the United States or of
     any state that are required in connection with the lawful issuance and sale
     of the  Securities  pursuant to this  Agreement  shall be duly obtained and
     effective as of the Closing.

          6.4 Minimum  Investment.  The Company shall have received an aggregate
     minimum investment from the Investors of $17,000,000.

     7. Termination.

          7.1 Right to  Termination.  This  Agreement may be terminated  and the
     proposed transactions abandoned:

               (a) At any time,  by mutual  written  consent of the  Company and
          Investors  committed  to purchase a majority of the Series 1 Preferred
          Stock;

               (b) At the  option of an  Investor  and by notice to the  Company
          stating  the  reasons  for such  action,  (i) in the event the Closing
          shall not have  occurred  by January  31, 2001 (or any other date that
          the  parties  may  designate  by  mutual  agreement)  by reason of the
          failure of any of the conditions set forth in Section 5 or (ii) at any
          time prior to the Closing, in the event of a material breach of any of
          the  representations or warranties by the Company set forth in Section
          2 or a material  breach of any of the  covenants  of the  Company  set
          forth in Section 4; or

               (c) At the option of the Company  and by notice to the  Investors
          stating  the  reasons  for such  action,  (i) in the event the Closing
          shall not have  occurred  by January  31, 2001 (or any other date that
          the  parties  may  designate  by  mutual  agreement)  by reason of the
          failure of any of the conditions set forth in Section 6 or (ii) at any
          time prior to the Closing, in the event of a material breach of any of
          the  representations  or  warranties  of the  Investors  set  forth in
          Section 3.

          7.2  Effect  of  Termination.  Termination  by  a  party  pursuant  to
     subsection  7.1(b) or  subsection  7.1(c) shall not  adversely  affect such
     party's other available rights and remedies. The rights and remedies of the
     party   terminating  this  Agreement   pursuant  to  subsection  7.1(b)  or
     subsection  7.1(c),  whether  contained  in  this  Agreement  or  conferred
     pursuant to applicable law or in equity, shall be cumulative and concurrent
     and may be pursued singly,  successively or together,  at the discretion of
     the holder thereof.



                                       16
<PAGE>
                                                            Page 37 of 92 Pages

     8. Miscellaneous.

          8.1  Survival  of  Warranties.  The  warranties,  representations  and
     covenants of the Company and the Investors contained in or made pursuant to
     this  Agreement  shall survive the execution and delivery of this Agreement
     and the Closing and shall in no way be affected by any investigation of the
     subject  matter  thereof  made  by or on  behalf  of the  Investors  or the
     Company.

          8.2 Successors and Assigns.  Except as otherwise  provided herein, the
     terms and conditions of this Agreement shall inure to the benefit of and be
     binding  upon  the  respective   successors  and  assigns  of  the  parties
     (including  transferees  of any  Securities).  Nothing  in this  Agreement,
     express or  implied,  is  intended  to confer upon any party other than the
     parties  hereto or their  respective  successors  and  assigns  any rights,
     remedies, obligations, or liabilities under or by reason of this Agreement,
     except as expressly provided in this Agreement.

          8.3 Governing Law. This  Agreement  shall be governed by and construed
     under the laws of the state of Oregon.

          8.4  Counterparts.  This  Agreement  may be  executed  in two or  more
     counterparts,  each of which shall be deemed an original,  but all of which
     together shall constitute one and the same instrument.

          8.5  Titles and  Subtitles.  The  titles  and  subtitles  used in this
     Agreement  are used for  convenience  only and are not to be  considered in
     construing or interpreting this Agreement.

          8.6  Notices.  Unless  otherwise  provided,  any  notice  required  or
     permitted  under  this  Agreement  shall be given in  writing  and shall be
     deemed effectively given upon personal delivery to the party to be notified
     or upon  deposit  with  the  United  States  Post  Office,  by  registered,
     certified mail, Federal Express, or other express courier,  postage prepaid
     and addressed to the party to be notified at the address indicated for such
     party on the signature page hereof,  or at such other address as such party
     may  designate  by ten (10)  days'  advance  written  notice  to the  other
     parties.  Any notice  given to the Company  under this Section 6.6 shall be
     copied via email to [email protected].

          8.7 Finder's Fee. Except for the Shemano Group and as otherwise as set
     forth in the Schedule of Exceptions,  each party represents that it neither
     is nor will be obligated  for any finders' fee or  commission in connection
     with  this  transaction.  The  Investors  agree  to  indemnify  and to hold
     harmless the Company from any liability for any commission or  compensation
     in the nature of a finders'  fee (and the costs and  expenses of  defending
     against such  liability or asserted  liability)  for which the Investors or
     any  of  their  officers,   partners,   employees,  or  representatives  is
     responsible.  The  Company  agrees  to  indemnify  and  hold  harmless  the
     Investors  from any liability for any  commission  or  compensation  in the
     nature of a finders' fee (and the costs and  expenses of defending  against
     such  liability or asserted  liability) for which the Company or any of its
     officers, employees or representatives is responsible.

          8.8 Expenses.  Each of the Company and the Investors  shall bear their
     own legal and other  expenses  incurred with respect to this  Agreement and
     the transactions


                                       17
<PAGE>
                                                            Page 38 of 92 Pages

     contemplated hereby; provided, however, that the Company shall pay up to an
     aggregate of $75,000 in the  reasonable  legal fees and expenses of counsel
     to the Investors,  contingent upon the Closing. The Investors shall require
     their  counsel to submit all  invoices  related to this  Agreement  and the
     transactions  contemplated  hereby to the Company's General Counsel for his
     review.

          8.9 Attorneys' Fees. If any action at law or in equity is necessary to
     enforce or interpret the terms of the Transaction Documents, the prevailing
     party shall be entitled to reasonable  attorney's fees, costs and necessary
     disbursements  in addition  to any other  relief to which such party may be
     entitled.

          8.10 Amendments and Waivers. Any term of this Agreement may be amended
     and the observance of any term or condition of this Agreement may be waived
     (either generally or in a particular  instance and either  retroactively or
     prospectively),  only  with the  written  consent  of the  Company  and the
     Investors  that have  purchased,  or, prior to the Closing,  have agreed to
     purchase,  a majority of the Shares.  Any  amendment or waiver  effected in
     accordance  with this  paragraph  shall be binding  upon each holder of any
     securities   purchased  under  this  Agreement  at  the  time   outstanding
     (including  securities  into which such securities are  convertible),  each
     future holder of all such securities, and the Company.

          8.11  Severability.  If one or more  provisions of this  Agreement are
     held to be  unenforceable  under  applicable  law, such provision  shall be
     excluded  from this  Agreement  and the balance of the  Agreement  shall be
     interpreted  as if such provision were so excluded and shall be enforceable
     in accordance with its terms.

          8.12 Entire  Agreement.  This Agreement and the documents  referred to
     herein constitute the entire agreement among the parties and no party shall
     be  liable  or bound to any other  party in any  manner by any  warranties,
     representations,  or covenants  except as specifically  set forth herein or
     therein.

          8.13  Restriction  on  Separate  Transfer  of  Warrants  and  Series 1
     Preferred Stock.  Until the first anniversary of the Closing,  no holder of
     Series 1 Preferred  Stock shall transfer,  sell,  assign or hypothecate any
     such shares without also transferring,  selling, assigning or hypothecating
     (a) Warrants to purchase a number of shares of Common Stock or (b) a number
     of shares of Common Stock  issued upon the exercise of Warrants,  in either
     case equal to one-half of the number of shares of Series 1 Preferred  Stock
     so transferred.


                                       18
<PAGE>
                                                            Page 39 of 92 Pages

     IN WITNESS WHEREOF, the parties have executed this Agreement as of the date
first above written.

                                     MEDICALOGIC/MEDSCAPE, INC.


                                     By:  _____________________________________
                                     Printed Name:  David Moffenbeier
                                     Title:  Chief Executive Officer

                                     Address:   20500 NW Evergreen Parkway
                                                Hillsboro, Oregon 97124



INVESTORS:                           QUANTUM INDUSTRIAL PARTNERS LDC


                                     By:  ______________________________________
                                     Its: ______________________________________
                                     Printed name: _____________________________


                                     Address:   c/o Curacao Corporation
                                                     Company NV
                                                Kaya Flamboyan 9,
                                                Villemstad, Curacao
                                                Netherlands Antilles



                                     SFM DOMESTIC INVESTMENTS LLC


                                     By:  ______________________________________
                                     Its: ______________________________________
                                     Printed name: _____________________________


                                     Address:  c/o Soros Private Equity Partners
                                               888 Seventh Avenue
                                               New York, NY  10106



                                       19
<PAGE>
                                                            Page 39 of 92 Pages

                                     PALLADIN GROUP


                                     By:  ______________________________________
                                     Its: ______________________________________
                                     Printed name: _____________________________

                                     Address: __________________________________
                                              __________________________________
                                              __________________________________


                                     GRUBER & McBAINE INTERNATIONAL


                                     By:  ______________________________________
                                     Its: ______________________________________
                                     Printed name: _____________________________

                                     Address: __________________________________
                                              __________________________________
                                              __________________________________


                                     HBK INVESTMENTS LP


                                     By:  ______________________________________
                                     Its: ______________________________________
                                     Printed name: _____________________________

                                     Address: __________________________________
                                              __________________________________
                                              __________________________________


                                     COLEMAN SWENSON HOFFMAN
                                     BOOTH IV, LP


                                     By:  ______________________________________
                                     Its: ______________________________________
                                     Printed name: _____________________________

                                     Address: __________________________________
                                              __________________________________
                                              __________________________________


                                       20
<PAGE>
                                                            Page 40 of 92 Pages


                                     CROSSLINK CROSSOVER FUND III, LP


                                     By:  ______________________________________
                                     Its: ______________________________________
                                     Printed name: _____________________________

                                     Address: __________________________________
                                              __________________________________
                                              __________________________________



                                     OFFSHORE CROSSLINK CROSSOVER
                                     FUND III, LP


                                     By:  ______________________________________
                                     Its: ______________________________________
                                     Printed name: _____________________________

                                     Address: __________________________________
                                              __________________________________
                                              __________________________________



                                     DELTA GROWTH, LP


                                     By:  ______________________________________
                                     Its: ______________________________________
                                     Printed name: _____________________________

                                     Address: __________________________________
                                              __________________________________
                                              __________________________________





                                       21
<PAGE>
                                                            Page 41 of 92 Pages

                                     RITCHIE CAPITAL MANAGEMENT



                                     By:  ______________________________________
                                     Its: ______________________________________
                                     Printed name: _____________________________

                                     Address: __________________________________
                                              __________________________________
                                              __________________________________



                                     CRANSHIRE CAPITAL



                                     By:  ______________________________________
                                     Its: ______________________________________
                                     Printed name: _____________________________

                                     Address: __________________________________
                                              __________________________________
                                              __________________________________


                                     LAGUNITAS PARTNERS LP


                                     By:  ______________________________________
                                     Its: ______________________________________
                                     Printed name: _____________________________

                                     Address: __________________________________
                                              __________________________________
                                              __________________________________



                                       22


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