John Hancock Institutional Series Trust
Supplement to the Prospectus dated January 10, 2000
John Hancock Active Bond Fund
On page 4, the "Portfolio Managers" section for the John Hancock Active Bond
Fund has been changed as follows:
PORTFOLIO MANAGERS
James K. Ho, CFA
Executive vice president of adviser
Joined team in 1995
Joined adviser in 1985
Began business career in 1977
Benjamin A. Matthews
Vice president of adviser
Joined team in 1995
Joined adviser in 1995
Began business career in 1970
5/22/00
